Family history of hypertension and cardiovascular reactivity to mental stress--effects of stimulus intensity and environment.

abstract：OBJECTIVE:Previous studies on multicellular preparations have shown that hypertrophied cardiac muscle from the spontaneously hypertensive rat (SHR) has a prolonged action potential. The first aim of the present study was to determine whether the action potential of isolated left ventricular myocytes was similarly prolo...

journal_title：Journal of hypertension

authors： Brooksby P,Levi AJ,Jones JV

更新日期：1993-06-01 00:00:00

abstract：OBJECTIVE:Microalbuminuria (MA) is a marker of adverse outcome in hypertension. The aim of this study was to investigate the association of MA with cardiovascular risk factors and glomerular hyperfiltration in the early stage of hypertension and to assess its predictive value for the development of sustained hypertensi...

journal_title：Journal of hypertension

authors： Palatini P,Mormino P,Mos L,Mazzer A,Dorigatti F,Zanata G,Longo D,Garbelotto R,De Toni R,Graniero G,Pessina AC,HARVEST Study Group.

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:To compare the reproducibility of clinic and ambulatory blood pressure measurements in elderly hypertensive subjects. SUBJECTS:Twenty-two untreated elderly hypertensives, with a clinic systolic blood pressure (SBP) > 160 mmHg and/or diastolic blood pressure (DBP) > 95 mmHg, and a mean age of 76 years (range...

journal_title：Journal of hypertension

authors： Fotherby MD,Potter JF

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:The effects of aspirin in subjects without cardiovascular disease are controversial. In the intensively treated patients of the Hypertension Optimal Treatment (HOT) Study, randomization to low-dose aspirin (75 mg daily) versus placebo significantly reduced cardiovascular events (-15%) and myocardial infarcti...

journal_title：Journal of hypertension

authors： Zanchetti A,Hansson L,Dahlöf B,Julius S,Ménard J,Warnold I,Wedel H,HOT Study Group.

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:To investigate the association between hypertension and musculoskeletal complaints among men and women selected by a population-based sample. METHODS:A cross-sectional study, with participants selected using a multistage sampling procedure and interviewed at home, was conducted to investigate the association...

journal_title：Journal of hypertension

authors： Kerkhoff AC,Moreira LB,Fuchs FD,Fuchs SC

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the influence of renal sympathetic nerves on the production of interleukin (IL)-6 in the kidney of normotensive Wistar rats and spontaneously hypertensive rats (SHR). DESIGN:In acute studies, the left kidney was exposed and the renal nerves were electrically stimulated to...

journal_title：Journal of hypertension

authors： Nakamura A,Kohsaka T,Johns EJ

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVES:To determine whether insulin sensitivity is impaired in normotensive offspring of essential hypertensives and to investigate how it relates to disturbed calcium metabolism. DESIGN:In 10 young lean, normotensive subjects with family histories of essential hypertension and in 10 age-matched controls we invest...

journal_title：Journal of hypertension

authors： Ohno Y,Suzuki H,Yamakawa H,Nakamura M,Otsuka K,Saruta T

更新日期：1993-04-01 00:00:00

abstract：:: The term 'cardiorenal syndrome' (CRS) was introduced to describe problems related to the simultaneous existence of heart and renal insufficiency. The prevalence of anaemia in CRS is high and increases the risk of hospitalizations and death. Renin-angiotensin system (RAS) inhibition is the cornerstone therapy in card...

journal_title：Journal of hypertension

authors： Vlahakos DV,Tsioufis C,Manolis A,Filippatos G,Marathias KP,Papademetriou V,Mancia G

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:We aimed to investigate whether adjustment for frailty influences the relationship of blood pressure with mortality in elderly patients with type 2 diabetes mellitus (T2DM). METHODS:Patients aged 60 years and older (n = 858) were selected from a prospective observational cohort study of primary care patients...

journal_title：Journal of hypertension

authors： van Hateren KJ,Hendriks SH,Groenier KH,Bakker SJ,Bilo HJ,Kleefstra N,Landman GW

更新日期：2015-06-01 00:00:00

abstract：RATIONALE:Cicletanine (CIC), an anti-hypertensive compound with direct vascular and natriuretic actions, is especially effective in salt-sensitive hypertension, in which dysregulation of the sodium pump plays an important pathogenic role, and digitalis-like cardiotonic steroids contribute to increased vascular tone. Th...

journal_title：Journal of hypertension

authors： Bagrov AY,Dmitrieva RI,Dorofeeva NA,Fedorova OV,Lopatin DA,Lakatta EG,Droy-Lefaix MT

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:Although an exaggerated systolic blood pressure (SBP) response to exercise is a predictor of future hypertension and cardiovascular mortality, the underlying mechanisms are not fully understood. We tested the hypothesis that an exaggerated SBP response is associated with carotid atherosclerosis in a cross-sec...

journal_title：Journal of hypertension

authors： Jae SY,Fernhall B,Heffernan KS,Kang M,Lee MK,Choi YH,Hong KP,Ahn ES,Park WH

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:To determine whether a diuretic can also reverse the clinical, systemic, renal and glomerular haemodynamic and pathological changes caused by nephrosclerosis. METHODS:Three groups of 20-week-old spontaneously hypertensive rats (SHR) were investigated: control male SHR; a similar group, administered 50 mg/l N...

journal_title：Journal of hypertension

authors： Ono Y,Ono H,Frohlich ED

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:To validate a computer-based method for measuring the calibre of retinal blood vessels, and use it to determine the effects of ageing and arterial hypertension on the calibres of these vessels and on their ratio. METHODS:Digital eye fundus images covering a 50 degrees field and centred on the optic disc were...

journal_title：Journal of hypertension

authors： Pose-Reino A,Gomez-Ulla F,Hayik B,Rodriguez-Fernández M,Carreira-Nouche MJ,Mosquera-González A,González-Penedo M,Gude F

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVES:The apolipoprotein epsilon 4 allele (APOE/epsilon 4) increases plasma cholesterol level and the risk for the late onset type of Alzheimer's disease. However, the correlation between hypertension and APOE/epsilon 4 has not yet been clarified. To examine the APOE/epsilon 4 effect in the general population of J...

journal_title：Journal of hypertension

authors： Katsuya T,Baba S,Ishikawa K,Mannami T,Fu Y,Inamoto N,Asai T,Fukuda M,Higaki J,Ogata J,Ogihara T

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVES:We hypothesized that addressing the 24-h relationship between RR interval and systolic arterial pressure (SAP) during ambulatory blood pressure monitoring could detect alterations in circadian arterial pressure and heart rate profile and could also be linked to the ambulatory arterial stiffness index. METHO...

journal_title：Journal of hypertension

authors： Pizzinelli P,Iellamo F,Beltrami S,Lucini D,Pagani M

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVES:Activation of the nuclear factor kappa B (NF kappaB) inflammatory pathway by angiotensin II and reactive oxygen species may play an important role in the development of insulin resistance and cardiovascular injury in hypertensive and metabolic diseases. We have shown that in hypertensive Dahl salt-sensitive ...

journal_title：Journal of hypertension

authors： Zhou MS,Schulman IH,Raij L

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to examine the reproducibility of arterial baroreflex sensitivity (BRS) provided by the spontaneous baroreflex method at rest and during laboratory tests. METHODS:Twenty healthy volunteers were studied 24 h apart, in the same laboratory and under the same environmental condit...

journal_title：Journal of hypertension

authors： Iellamo F,Legramante JM,Raimondi G,Castrucci F,Massaro M,Peruzzi G

更新日期：1996-09-01 00:00:00

abstract：:Blood pressure, plethysmographically determined muscle blood flow in the calf at rest and during maximal dilatation, plasma renin activity, angiotensin II and plasma and urinary aldosterone were determined in normotensive men with a positive family history of hypertension (n = 17) and in an age- and weight-matched con...

journal_title：Journal of hypertension

authors： Gudmundsson O,Andersson OK,Aurell M,Wikstrand JM,Berglund GL

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVE:To assess the dilatory effectiveness of nitric oxide donors in resistance arteries of patients with arterial hypertension in comparison with that in those of normotensive controls. BACKGROUND:Endothelium-dependent vasodilation has been demonstrated to be impaired in arterial hypertension. Besides disturbance...

journal_title：Journal of hypertension

authors： Preik M,Kelm M,Feelisch M,Strauer BE

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:To audit the performances of the analytes used in the diagnosis of pheochromocytoma and to present a graphical guideline to help the diagnosis. DESIGN:A 5 year retrospective study. SETTINGS:Laboratory and departments of a university hospital. PARTICIPANTS:In-patients, suspected of bearing a pheochromocytom...

journal_title：Journal of hypertension

authors： Gardet V,Gatta B,Simonnet G,Tabarin A,Chêne G,Ducassou D,Corcuff JB

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:Increased endothelial production of reactive oxygen species and decreased nitric oxide bioactivity, associated with the upregulation of monocyte chemoattractant protein (MCP)-1 and lectin-like oxidized low-density lipoprotein receptor (LOX)-1, link hypertension with atherogenesis. We investigated whether the...

journal_title：Journal of hypertension

authors： Zhou MS,Schulman IH,Jaimes EA,Raij L

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Increased arterial stiffness is associated with cardiovascular morbidity and mortality among hypertensive patients. OBJECTIVES:To assess the relationship between ambulatory arterial stiffness index (AASI) and subclinical left ventricular (LV) systolic dysfunction assessed by 2-D speckle-tracking echocardiog...

journal_title：Journal of hypertension

authors： Ahmed TAN,Shams-Eddin H,Fathy MA,El-Naggar HM,Kishk YT

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The Glu298Asp, T786C and 4a/4b genetic polymorphisms within the endothelial nitric oxide synthase (e-NOS) gene may predispose to hypertension, ischaemic heart disease and renal damage, possibly by reducing the generation of nitric oxide (NO), a fundamental substance in renal and cardiovascular biology. That ...

journal_title：Journal of hypertension

authors： Dell'Omo G,Penno G,Pucci L,Fotino C,Lucchesi D,Del Prato S,Pedrinelli R

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:We assessed hypertension prevalence, blood pressure (BP)-lowering treatment and control in obese adults compared with lean/normal-weight individuals in France. METHODS:Multistage stratified random sample of 2075 adults from the French Nutrition and Health Survey (ENNS), a cross-sectional national survey carr...

journal_title：Journal of hypertension

authors： Czernichow S,Castetbon K,Salanave B,Vernay M,Barry Y,Batty GD,Hercberg S,Blacher J

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Sitagliptin, a new antidiabetic drug that inhibits dipeptidyl peptidase (DPP)-4 enzyme activity, has been reported to possess neuroprotective property. We tested the protective effects of sitagliptin against chronic cerebral hypoperfusion (CHP) in mice after bilateral carotid artery stenosis (BCAS). METHOD:...

journal_title：Journal of hypertension

authors： Tsai TH,Sun CK,Su CH,Sung PH,Chua S,Zhen YY,Leu S,Chang HW,Yang JL,Yip HK

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Recent cross-sectional studies have suggested that higher serum sodium levels may be a marker of elevated blood pressure. It is unclear whether serum sodium levels are related to the risk of developing hypertension in the community. METHODS:We investigated the association of serum sodium with longitudinal b...

journal_title：Journal of hypertension

authors： Lago RM,Pencina MJ,Wang TJ,Lanier KJ,D'Agostino RB,Kannel WB,Vasan RS

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:Night-time ambulatory blood pressure (nABP) is the most important aspect of the blood pressure profile in terms of prognosis. Novel low-cost home monitors allow automated night-time blood pressure monitoring (nHBP). This study reviewed the evidence on the association of nHBP with nABP and preclinical organ da...

journal_title：Journal of hypertension

authors： Kollias A,Ntineri A,Stergiou GS

更新日期：2017-03-01 00:00:00

abstract：:The effect of xipamide on the intracellular concentration and transmembrane fluxes of Na+ and K+ was studied in 12 normal male subjects, using a double-blind cross-over design. After a run-in period on placebo for 1 week, the subjects were treated with either placebo (n = 6) or xipamide 20 mg once a day (n = 6) for 16...

journal_title：Journal of hypertension

authors： Lijnen P,Hespel P,Fagard R,Staessen J,Goossens W,Lissens W,Amery A

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVES:Enhanced central sympathetic outflow is an indicator of the prognosis of heart failure. Although the central sympatholytic drug moxonidine is an established therapeutic strategy for hypertension, its benefits for hypertensive heart failure are poorly understood. In the present study, we investigated the effe...

journal_title：Journal of hypertension

authors： Honda N,Hirooka Y,Ito K,Matsukawa R,Shinohara K,Kishi T,Yasukawa K,Utsumi H,Sunagawa K

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Comprehensive studies have confirmed that particulate matter air pollution could trigger myocardial infarction, heart failure and reduce heart rate variability; however, its effect on blood pressure (BP) remains controversial. Therefore, we did a systematic review and meta-analysis to investigate the associa...

journal_title：Journal of hypertension

authors： Liang R,Zhang B,Zhao X,Ruan Y,Lian H,Fan Z

更新日期：2014-11-01 00:00:00