Lessons from an unpleasant surprise: a biochemical strategy for the diagnosis of pheochromocytoma.

abstract：BACKGROUND:Few studies have directly compared the effects of different angiotensin receptor blockers (ARBs) on mechanisms involved in the pathogenesis of cardiovascular disease. METHODS:We studied the ability of different ARBs to inhibit the proliferation of vascular smooth muscle cells (VSMCs) and cardiac fibroblasts...

journal_title：Journal of hypertension

authors： Benson SC,Iguchi R,Ho CI,Yamamoto K,Kurtz TW

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:In familial hyperaldosteronism type I (FH-I), glucocorticoid treatment suppresses adrenocorticotrophic hormone-regulated hybrid gene expression and corrects hyperaldosteronism. OBJECTIVE:To determine whether the wild-type aldosterone synthase genes, thereby released from chronic suppression, are capable of ...

journal_title：Journal of hypertension

authors： Stowasser M,Taylor WL,Gartside MG,Tunny TJ,Gordon RD

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:BPH/2J hypertensive mice have an exaggerated sympathetic contribution to blood pressure (BP). Premotor sympathetic neurons within the rostroventrolateral medulla (RVLM) are a major source of sympathetic vasomotor tone and major site of action of the centrally acting sympatholytic agent, rilmenidine. The relat...

journal_title：Journal of hypertension

authors： Jackson KL,Palma-Rigo K,Nguyen-Huu TP,Davern PJ,Head GA

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To investigate whether a dietary supplement of vitamin B6 could attenuate the elevation of systolic blood pressure (SBP) in Zucker obese or spontaneously hypertensive rats, or rats ingesting sucrose. METHODS:Zucker obese rats (fa/fa), Sprague-Dawley rats with sucrose-induced elevation of SBP, spontaneously h...

journal_title：Journal of hypertension

authors： Lal KJ,Dakshinamurti K,Thliveris J

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:Few data are available comparing the effects of monotherapy and combination therapy on target organ damage. The PICXEL study compared the efficacy of a strategy based on first-line combination with perindopril/indapamide versus monotherapy with enalapril in reducing left ventricular hypertrophy (LVH) in hyper...

journal_title：Journal of hypertension

authors： Dahlöf B,Gosse P,Guéret P,Dubourg O,de Simone G,Schmieder R,Karpov Y,García-Puig J,Matos L,De Leeuw PW,Degaute JP,Magometschnigg D,PICXEL Investigators.

更新日期：2005-11-01 00:00:00

abstract：:The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 confirms ischemic heart disease and stroke as the leading cause of death and that hypertension is the main associated risk factor worldwide. How best to respond to the rising prevalence of hypertension in resource-deprived settings is a topic of ongo...

journal_title：Journal of hypertension

authors： Modesti PA,Agostoni P,Agyemang C,Basu S,Benetos A,Cappuccio FP,Ceriello A,Del Prato S,Kalyesubula R,O'Brien E,Kilama MO,Perlini S,Picano E,Reboldi G,Remuzzi G,Stuckler D,Twagirumukiza M,Van Bortel LM,Watfa G,Zhao D

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:The aim of this cross-sectional study was to investigate the association between consumption of sugar-sweetened and diet soft drinks with blood pressure (BP) in adolescents. METHODS:Fifth graders of 20 public schools were invited to participate in an intervention aimed at behavioral dietary changes and had t...

journal_title：Journal of hypertension

authors： Souza Bda S,Cunha DB,Pereira RA,Sichieri R

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Left-ventricular hypertrophy (LVH) is a marker of organ damage in hypertension and helps stratifying cardiovascular risk. Initial left-ventricular mass (LVM) is also a predictor of progression to hypertension, independently of initial blood pressure (BP) and other confounders. OBJECTIVES:To evaluate whether...

journal_title：Journal of hypertension

authors： Izzo R,de Simone G,Devereux RB,Giudice R,De Marco M,Cimmino CS,Vasta A,De Luca N,Trimarco B

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Dopamine receptors induce natriuresis in kidney. Previous studies have shown interactions between different subtypes of dopamine receptors in renal proximal tubule (RPT) cells. We hypothesize that D3 receptors have an interaction with D4 receptors in RPT cells from normotensive rats (Wistar-Kyoto, WKY) and s...

journal_title：Journal of hypertension

authors： Chen X,Liu Y,Wang WE,Chen C,Ren H,Zheng S,Zhou L,Zeng C

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Fibromuscular dysplasia (FMD) and atherosclerotic renal artery stenosis (ARAS) are the most common causes of renovascular hypertension. So far, FMD is believed to cause hypertension via similar mechanisms as in ARAS, that is, a decrease in renal blood flow, which subsequently leads to increased renin secreti...

journal_title：Journal of hypertension

authors： van Twist DJ,Houben AJ,de Haan MW,de Leeuw PW,Kroon AA

更新日期：2017-04-01 00:00:00

abstract：:This paper describes the kinetics of the Na(+)-K+ pump and the Na(+)-K(+)-Cl- cotransport in sodium-loaded erythrocytes and of the Na(+)-K(+)-Cl- cotransport in erythrocyte inside-out vesicles (IOV) from Milan hypertensive (MHS) and normotensive (MNS) rats in order to evaluate the possible role of intracellular factor...

journal_title：Journal of hypertension

authors： Ferrari P,Torielli L,Cirillo M,Salardi S,Bianchi G

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVES:Many different stress echocardiographic and radionuclide perfusion imaging tests have been proposed for detecting epicardial coronary artery disease (CAD) in hypertensive patients. Their relative diagnostic and prognostic value has not been exactly established. BACKGROUND:A positive exercise electrocardiogr...

journal_title：Journal of hypertension

authors： Astarita C,Pálinkás A,Nicolai E,Maresca FS,Varga A,Picano E

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:This study was designed to evaluate the capacity of norepinephrine (NE) to induce hypertrophic remodeling of small arteries in rats, and to determine the involvement of endothelin (ET) to initiate and maintain it. DESIGN AND RESULTS:Treatment with NE (2.5 microg/kg per min) for 14 or 28 days produced a simil...

journal_title：Journal of hypertension

authors： Dao HH,Martens FM,Larivière R,Yamaguchi N,Cernacek P,de Champlain J,Moreau P

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVES:To determine whether vigorous exercise and alcohol restriction have additive and independent effects in reducing blood pressure in sedentary male alcohol drinkers. Also to assess whether 4 weeks of vigorous exercise could offset the fall in high-density lipoprotein cholesterol (HDL-cholesterol) usually obser...

journal_title：Journal of hypertension

authors： Cox KL,Puddey IB,Morton AR,Beilin LJ,Vandongen R,Masarei JR

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVE:To investigate methods to diagnose renal artery stenosis (RAS) among the general hypertensive population. METHODS:We studied the value of clinical and biochemical characteristics at the outpatient clinic to identify subjects with a renal artery narrowing of more than 50% of the luminal surface among 1047 hyp...

journal_title：Journal of hypertension

authors： Bijlstra PJ,Postma CT,de Boo T,Thien T

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVES:Scarce data exist on blood pressure (BP) and secondary effects in young athletes. Hence, we aimed to study prevalence of high BP (≥140/90 mmHg) and the association to arterial compliance, left ventricle mass and left atrium volume. METHODS:A Norwegian preparticipation cardiac screening of male professional ...

journal_title：Journal of hypertension

authors： Berge HM,Gjerdalen GF,Andersen TE,Solberg EE,Steine K

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVES:To assess the prevalence of episodes of ST-segment depression in a population of consecutive patients with mild-to-moderate essential hypertension who are free of clinical signs of coronary artery disease. METHODS:The study involved 28 Italian centers that enrolled 414 hypertensive patients (aged 50-70 year...

journal_title：Journal of hypertension

authors： Stramba-Badiale M,Bonazzi O,Casadei G,Dal Palù C,Magnani B,Zanchetti A

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:Left atrial (LA) enlargement is an index of adverse cardiovascular events. We sought to investigate any possible correlation between haemodynamic load, neurohumoral factors and LA size in the early stages of essential hypertension. METHODS:We studied 94 consecutive middle-aged subjects, with newly diagnosed ...

journal_title：Journal of hypertension

authors： Tsioufis C,Stougiannos P,Taxiarchou E,Skiadas I,Chatzis D,Thomopoulos C,Lalos S,Stefanadis C,Kallikazaros I

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVES:Female sexual dysfunction (FSD) is increasingly attracting more scientific and public interest, and represents a poorly investigated issue in patients with essential hypertension. We evaluated the prevalence of sexual dysfunction in hypertensive women compared with normotensive women according to age, hypert...

journal_title：Journal of hypertension

authors： Doumas M,Tsiodras S,Tsakiris A,Douma S,Chounta A,Papadopoulos A,Kanellakopoulou K,Giamarellou H

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:Salt sensitivity and the magnitude of systolic blood pressure have been linked to haptoglobin (Hp) polymorphism in normotensives. The aim of the present study was to investigate the indices of hypertension, the severity of complications and the occurrence of coronary and peripheral artery disease for the vari...

journal_title：Journal of hypertension

authors： Delanghe JR,Duprez DA,De Buyzere ML,Bergez BM,Callens BY,Leroux-Roels GG,Clement DL

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Contrary to lay beliefs, current perceived stress is not consistently associated with the incidence of high blood pressure (BP) in prospective studies, possibly because of moderating factors. The present prospective study examined this association and explored the potential moderating effects of sex or occup...

journal_title：Journal of hypertension

authors： Wiernik E,Nabi H,Pannier B,Czernichow S,Hanon O,Simon T,Simon JM,Thomas F,Ducolombier C,Danchin N,Limosin F,Consoli SM,Lemogne C

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:Phenotypic transformation of adventitial fibroblasts is important in the pathogenesis of hypertension. This study was designed to determine whether fibronectin type III domain containing 5 (FNDC5) alleviates the phenotypic transformation of adventitial fibroblasts in hypertension and the underlying mechanisms...

journal_title：Journal of hypertension

authors： Ling L,Chen D,Tong Y,Zang YH,Ren XS,Zhou H,Qi XH,Chen Q,Li YH,Kang YM,Zhu GQ

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:High sodium intake is associated with increased risk of end-organ damage, independent of blood pressure (BP) levels. The protective peptide adiponectin may play a role in the pathogenesis of hypertension and particularly in salt-loaded conditions. Furthermore, increased adiponectin levels were observed in sa...

journal_title：Journal of hypertension

authors： Kamari Y,Shimoni N,Koren F,Peleg E,Sharabi Y,Grossman E

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Choice of antihypertensive drugs is also based on the expected burden of adverse events associated with each class of agents, and we have recently identified treatment discontinuation for adverse events as a measure of treatment tolerability frequently reported in randomized controlled trials (RCTs). OBJECT...

journal_title：Journal of hypertension

authors： Thomopoulos C,Parati G,Zanchetti A

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:There are no studies that relate BsmI polymorphism of the vitamin D receptor (VDR) gene and with vitamin D to blood pressure (BP). OBJECTIVE:To analyze if this polymorphism and 25-hydroxyvitamin D levels (25OHD3) influence BP in a population of healthy subjects. DESIGN:Transversal study on healthy populati...

journal_title：Journal of hypertension

authors： Muray S,Parisi E,Cardús A,Craver L,Fernández E

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To determine adrenocorticotrophin dose-response relationships for increase of blood pressure and metabolic parameters of the Sprague-Dawley rat. METHODS:We injected 120 male Sprague-Dawley rats twice daily subcutaneously for 10 days with 0.5, 1, 5, 50, 100, 200 or 500 microg/kg synthetic adrenocorticotrophin...

journal_title：Journal of hypertension

authors： Turner SW,Wen C,Li M,Fraser TB,Whitworth JA

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:Various studies have suggested that a delay in the time between diagnosing hypertension and its correct control (D-C, diagnostic-control time) is linked to a worse prognosis. The aim of this study was to examine the relationship between D-C time and all-cause mortality, or the incidence of cardiovascular even...

journal_title：Journal of hypertension

authors： Martín-Fernández M,Vinyoles E,Real J,Soldevila N,Muñoz MÁ,Del-Val JL,Verdú JM,Domingo M,Mundet X

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:The prognostic role of endothelial dysfunction, as evaluated by flow-mediated vasodilatation of the brachial artery, has been demonstrated in patients at very high risk. We aimed to investigate whether flow-mediated vasodilatation predicts cardiovascular events in uncomplicated hypertensive patients. METHOD...

journal_title：Journal of hypertension

authors： Muiesan ML,Salvetti M,Paini A,Monteduro C,Galbassini G,Poisa P,Porteri E,Agabiti-Rosei C,Paderno V,Belotti E,Rizzoni D,Castellano M,Agabiti-Rosei E

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The difference between clinic and ambulatory blood pressure (BP) is a poor estimate of the true white-coat effect (WCE) measured with beat-to-beat recording. METHOD:We investigated whether the difference between clinic and home BP (home WCE) was a better estimate of true WCE than ambulatory WCE. In 73 young...

journal_title：Journal of hypertension

authors： Saladini F,Benetti E,Malipiero G,Casiglia E,Palatini P

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Widely evaluated regarding the genetic make-up of essential hypertension are the renin-angiotensin-aldosterone system (RAAS) genes polymorphisms, whereas results are often not reproducible. METHOD:We thus focused on a large Fangshan population to explore association of thirteen polymorphisms in five genes o...

journal_title：Journal of hypertension

authors： Niu W,Qi Y,Hou S,Zhai X,Zhou W,Qiu C

更新日期：2009-07-01 00:00:00