Influence of vitamin D receptor gene polymorphisms and 25-hydroxyvitamin D on blood pressure in apparently healthy subjects.

abstract：OBJECTIVE:To test the hypothesis that combination therapy might be a powerful tool to reduce blood pressure variability (BPV) in the treatment of hypertension. METHODS:In chronic studies, male spontaneously hypertensive rats were given drugs in their rat chow for 18 weeks (n = 9 or 10 for each group of rats). Doses we...

journal_title：Journal of hypertension

authors： Xie HH,Shen FM,Xu LP,Han P,Miao CY,Su DF

更新日期：2007-11-01 00:00:00

abstract：:To evaluate factors influencing hemodynamic responses to psychological and physical stress, 117 normotensive college students were studied. The standardized tests included arithmetic, Stroop word-color, mirror draw, isometric handgrip and cold pressor challenges. The responses of blood pressure and pulse during the te...

journal_title：Journal of hypertension

authors： McAdoo WG,Weinberger MH,Miller JZ,Fineberg NS,Grim CE

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVES:Retinal blood vessels may develop vasculopathy and apoptosis in response to hypertension. The present study was aimed at testing the role of losartan, a specific antagonist of angiotensin II receptor type 1 receptor in regulation of vascular apoptosis in retinal vasculature with hypertension. METHODS:Losart...

journal_title：Journal of hypertension

authors： Yang D,Zhang M,Huang X,Fang F,Chen B,Wang S,Cai J,Shi X,Qu J,Geng YJ

更新日期：2010-03-01 00:00:00

abstract：:Uptake of 45Ca was measured in rings of thoracic aorta from rabbits with hypertension, induced by cellophane perinephritis (Page hypertension: one-kidney, one wrap). Basal 45Ca uptake was increased significantly in the hypertensive group (sham: 100 +/- 3, hypertensive: 133 +/- 11 nmol/g wet weight, n = 6). 45Ca uptake...

journal_title：Journal of hypertension

authors： Dong Y,Wadsworth RM

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVES:Several studies have shown lower carotid-femoral pulse wave velocity (cfPWV) levels in women compared to men, a difference that could partially explain the increased longevity in women. However, these studies have been performed in industrial countries while few data are available in emerging populations. We...

journal_title：Journal of hypertension

authors： Temmar M,Watfa G,Joly L,Kearney-Schwartz A,Youcef M,Bensalah S,Mustapha Y,Salvi P,Gautier S,Safar M,Labat C,Benetos A

更新日期：2013-11-01 00:00:00

abstract：:We have examined the mechanisms mediating the release of renin elicited in man by reduction of renal perfusion pressure. Fifteen patients with essential hypertension and six normotensive subjects were investigated during diagnostic renal arteriography. Renal neural receptors were inhibited by propranolol (10 mg i.v.) ...

journal_title：Journal of hypertension

authors： Guazzi MD,Barbier P,Loaldi A,Montorsi P,Polese A,Tosi E,Fiorentini C

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:High sodium intake is associated with increased risk of end-organ damage, independent of blood pressure (BP) levels. The protective peptide adiponectin may play a role in the pathogenesis of hypertension and particularly in salt-loaded conditions. Furthermore, increased adiponectin levels were observed in sa...

journal_title：Journal of hypertension

authors： Kamari Y,Shimoni N,Koren F,Peleg E,Sharabi Y,Grossman E

更新日期：2010-01-01 00:00:00

abstract：:Blood pressure was measured in 864 young people aged 16-24 years, 8 years after both of their parents had their blood pressures measured as part of the screening phase of the Medical Research Council Mild Hypertension Trial. Only 29% of offspring with a conventional 'family history of hypertension', defined in terms o...

journal_title：Journal of hypertension

authors： Watt GC,Foy CJ,Holton DW,Edwards HE

更新日期：1991-01-01 00:00:00

abstract：:Medical records were examined for 1935 patients who presented sequentially to a hypertension clinic between 1971 and 1981. Patients were classified according to whether they were on a beta-blocker, methyldopa, a potassium-losing diuretic, or whether they had discontinued any of these treatments. Age-standardized morta...

journal_title：Journal of hypertension

authors： Franks PJ,Hartley K,Bulpitt PF,Bulpitt CJ,Dollery CT

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:To study 24-h ambulatory blood pressure (BP) and development of hypertension over four decades in women with childhood urinary tract infection (UTI) associated with renal damage. METHODS:A population-based group of 111 women was followed from their first UTI in childhood. The cohort was investigated at a med...

journal_title：Journal of hypertension

authors： Gebäck C,Hansson S,Himmelmann A,Sandberg T,Sixt R,Jodal U

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To examine the association between the graded exercise systolic blood pressure (SBP) response and left ventricular (LV) geometric structure in patients with untreated mild hypertension. PARTICIPANTS:The study included 80 sedentary, overweight patients (43 female and 37 male) with unmedicated high normal bloo...

journal_title：Journal of hypertension

authors： Pierson LM,Bacon SL,Sherwood A,Hinderliter AL,Babyak M,Gullette EC,Waugh R,Blumenthal JA

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:Salt sensitivity and the magnitude of systolic blood pressure have been linked to haptoglobin (Hp) polymorphism in normotensives. The aim of the present study was to investigate the indices of hypertension, the severity of complications and the occurrence of coronary and peripheral artery disease for the vari...

journal_title：Journal of hypertension

authors： Delanghe JR,Duprez DA,De Buyzere ML,Bergez BM,Callens BY,Leroux-Roels GG,Clement DL

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:To identify predictors of pregnancy-induced hypertension and pre-eclampsia in 212 nulliparous women before 20 weeks' gestation and at approximately 28 weeks' gestation. STUDY DESIGN:A randomized, prospective study in a teaching hospital. We performed standardized measurements of systolic and diastolic arteri...

journal_title：Journal of hypertension

authors： Broughton Pipkin F,Sharif J,Lal S

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVE:The main objective was to examine the role of hemodynamics in rat aortic and left ventricular hypertrophy produced by sinoaortic denervation (SAD). DESIGN AND METHODS:Rats were examined at different times after SAD or sham operation (Sham). Hemodynamics were recorded continuously in conscious unrestrained ra...

journal_title：Journal of hypertension

authors： Miao CY,Su DF

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to examine the associations of birth outcomes and longitudinally measured fetal and infant growth patterns with retinal vessel calibers in childhood. METHODS:In a population-based prospective cohort study among 4122 children, we measured growth characteristics in second and third tri...

journal_title：Journal of hypertension

authors： Gishti O,Jaddoe VW,Duijts L,Steegers E,Reiss I,Hofman A,Wong TY,Ikram MK,Gaillard R

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:We have previously shown that conduit arteries of normotensive (WKY) and hypertensive (SHR) Japanese rats differ from normotensive (LN) and hypertensive (LH) Lyon rats in terms of lower aortic thickness and higher collagen III content, whereas differences in vasoactive properties are unknown. METHODS:Aortic ...

journal_title：Journal of hypertension

authors： Chamiot-Clerc P,Legrand M,Sassard J,Safar ME,Renaud JF

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVES:Hemodialysis patients have a cardiovascular mortality rate of 20-40 times that of the general population. Aldosterone inhibition by spironolactone has exerted beneficial, prognostically significant cardiovascular effects in patients with heart failure maintained on hemodialysis or peritoneal dialysis. Our ai...

journal_title：Journal of hypertension

authors： Flevari P,Kalogeropoulou S,Drakou A,Leftheriotis D,Panou F,Lekakis J,Kremastinos D,Vlahakos DV

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Caffeine is the most widely used pharmacologically active substance. Aortic elastic properties and arterial wave reflection are important factors for the efficient performance of the cardiovascular system, as well as prognosticators of cardiovascular risk. We investigated the effect of caffeine on aortic elas...

journal_title：Journal of hypertension

authors： Vlachopoulos C,Hirata K,O'Rourke MF

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:Traditional cardiovascular risk factors do not fully account for ethnic differences in cardiovascular disease. We tested if arterial function indices, particularly augmentation index (AIx), and their determinants from childhood could underlie such ethnic variability among young British adults in the 'DASH' lo...

journal_title：Journal of hypertension

authors： Faconti L,Silva MJ,Molaodi OR,Enayat ZE,Cassidy A,Karamanos A,Nanino E,Read UM,Dall P,Stansfield B,Harding S,Cruickshank KJ

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:We investigated the impact of renal function on outcomes after percutaneous transluminal angioplasty. METHODS:A total of 139 hypertensive patients with atherosclerotic renal artery stenosis (mean age, 70 years, 80.6% men) who underwent renal percutaneous transluminal angioplasty were included. Renal function...

journal_title：Journal of hypertension

authors： Iwashima Y,Fukuda T,Horio T,Hayashi SI,Kusunoki H,Kishida M,Nakamura S,Kamide K,Kawano Y,Yoshihara F

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To assess the antihypertensive efficacy and safety of the novel AT1 receptor antagonist, telmisartan, compared with that of enalapril in elderly patients with mild to moderate hypertension. DESIGN:A 26-week, multicenter, double-blind, parallel-group, dosage titration study. METHODS:A total of 278 patients a...

journal_title：Journal of hypertension

authors： Karlberg BE,Lins LE,Hermansson K

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Cathepsin L (CTSL1) catalyzes the formation of peptides that influence blood pressure (BP). Naturally occurring genetic variation or targeted ablation of the Ctsl1 locus in mice yield cardiovascular pathology. Here, we searched for genetic variation across the human CTSL1 locus and probed its functional effe...

journal_title：Journal of hypertension

authors： Mbewe-Campbell N,Wei Z,Zhang K,Friese RS,Mahata M,Schork AJ,Rao F,Chiron S,Biswas N,Kim HS,Mahata SK,Waalen J,Nievergelt CM,Hook VY,O'Connor DT

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To compare the effects of a cardioselective beta-blocker (nebivolol) with those of an angiotensin-converting enzyme inhibitor (enalapril) on parameters of insulin sensitivity, peripheral blood flow and arterial stiffness during one extended glucose clamp experiment. DESIGN:A randomized, double-blind crossove...

journal_title：Journal of hypertension

authors： Kaiser T,Heise T,Nosek L,Eckers U,Sawicki PT

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:To describe patterns of hypertension history in patients with various types of end-stage renal disease (ESRD) and in persons with normal kidney function; and to identify risk factors for the diagnosis 'hypertensive ESRD'. DESIGN:A case-control study. SETTING:Population-based. PARTICIPANTS:Patients with ES...

journal_title：Journal of hypertension

authors： Perneger TV,Whelton PK,Klag MJ

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Anandamide (AEA), one of the endocannabinoid compounds, has an important regulatory function by serving as an autocrine/paracrine or endocrine factor throughout the body via activation of the cannabinoid receptor 1 (CB1) and/or the transient receptor potential vanilloid type 1 (TRPV1) channels. However, the ...

journal_title：Journal of hypertension

authors： Li J,Wang DH

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Contrary to lay beliefs, current perceived stress is not consistently associated with the incidence of high blood pressure (BP) in prospective studies, possibly because of moderating factors. The present prospective study examined this association and explored the potential moderating effects of sex or occup...

journal_title：Journal of hypertension

authors： Wiernik E,Nabi H,Pannier B,Czernichow S,Hanon O,Simon T,Simon JM,Thomas F,Ducolombier C,Danchin N,Limosin F,Consoli SM,Lemogne C

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:Insulin-mediated vasodilation has been shown to be impaired with hypertension and aggravated by dietary sodium restriction. Whether vascular insulin resistance in this setting could be improved by antihypertensive therapy was unknown. Therefore, we determined the effect of therapy with an angiotensin-converti...

journal_title：Journal of hypertension

authors： Feldman RD,Schmidt ND

更新日期：2001-01-01 00:00:00

abstract：:An Na+,K+-ATPase inhibitor possessing inhibitory activity against the specific binding of ouabain to Na+,K+-ATPase has been purified from the plasma of acutely saline-infused hogs. The purification was performed by a combination of Amberlite XAD-2 adsorption chromatography and five steps of high-pressure liquid chroma...

journal_title：Journal of hypertension

authors： Tamura M,Inagami T,Kinoshita T,Kuwano H

更新日期：1987-04-01 00:00:00

abstract：OBJECTIVE:Blood pressure (BP) load, defined as the percentage of abnormally elevated BP readings, is usually provided on the report of ambulatory BP monitoring. However, the usefulness of BP load is still uncertain. In the present study, we examined whether BP load would be associated, independently of BP level, with t...

journal_title：Journal of hypertension

authors： Liu M,Li Y,Wei FF,Zhang L,Han JL,Wang JG

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:Reduction in capillary density or rarefaction is a hallmark of essential hypertension. We measured the retinal capillary density using noninvasive optical coherence tomographic angiography (OCT-A) in adults with treated systemic hypertension and determined possible correlations with ambulatory blood pressure ...

journal_title：Journal of hypertension

authors： Chua J,Chin CWL,Hong J,Chee ML,Le TT,Ting DSW,Wong TY,Schmetterer L

更新日期：2019-03-01 00:00:00