Intrarenal beta-receptor and renal baroreceptor interaction in the control of the renin response to transient reduction of the renal perfusion pressure in man.

abstract：OBJECTIVE:The genetic background of orthostatic hypotension, an important risk factor for future cardiovascular morbidity and mortality, was investigated. DESIGN AND METHODS:The study subjects comprised 415 community-dwelling individuals, who were free from any cardiovascular complications, aged 50 years or older (mea...

journal_title：Journal of hypertension

authors： Tabara Y,Kohara K,Miki T

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:We investigated the responses of mean arterial pressure and renal blood flow to intravenous and intrarenal angiotensin II, plasma and kidney angiotensin II concentrations and renal angiotensin receptor subtype 1 protein expression, and renal functional responses to intravenous and intrarenal angiotensin recep...

journal_title：Journal of hypertension

authors： Kopkan L,Kramer HJ,Husková Z,Vanourková Z,Skaroupková P,Thurmová M,Cervenka L

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:To determine whether the decision to treat uncomplicated mild hypertension with drugs, in accordance with the World Health Organization - International Society of Hypertension (WHO/ISH) guidelines based on a series of blood pressure (BP) measurements over 6 months, resulted in the treatment of patients at hig...

journal_title：Journal of hypertension

authors： Abergel E,Chatellier G,Battaglia C,Menard J

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:To search for a genetic marker of the sarco(endo)plasmic reticulum Ca(2+)-dependent ATPase (SERCA) II gene in spontaneously hypertensive rats (SHRs) and to investigate differences in blood pressure and intracellular Ca2+ among some substrains of SHRs and Wistar-Kyoto (WKY) rats related to their SERCA II genot...

journal_title：Journal of hypertension

authors： Ohno Y,Matsuo K,Suzuki H,Tanase H,Ikeshima H,Takano T,Saruta T

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Enhanced mechanical forces, e.g. in arterial hypertension, stimulate the formation of reactive oxygen species (ROS) by the NAD(P)H oxidase. Since bone marrow derived endothelial progenitor cells (EPCs) contribute to vascular remodeling and repair, we investigated whether renovascular hypertension stimulates ...

journal_title：Journal of hypertension

authors： Salguero G,Akin E,Templin C,Kotlarz D,Doerries C,Landmesser U,Grote K,Schieffer B

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Widely evaluated regarding the genetic make-up of essential hypertension are the renin-angiotensin-aldosterone system (RAAS) genes polymorphisms, whereas results are often not reproducible. METHOD:We thus focused on a large Fangshan population to explore association of thirteen polymorphisms in five genes o...

journal_title：Journal of hypertension

authors： Niu W,Qi Y,Hou S,Zhai X,Zhou W,Qiu C

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to investigate the haemodynamic effects of hormonal changes during the menstrual cycle in 11 hypertensive women aged between 29 and 38 years. DESIGN:In randomized order, the subjects were examined on days 2-7 (follicular phase) and on days 20-24 (luteal phase). All medication was wit...

journal_title：Journal of hypertension

authors： Manhem K,Jern C,Pilhall M,Hansson L,Jern S

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVE:Metabolic syndrome is associated with a high risk of cardiovascular disease in hypertension. We evaluated whether metabolic syndrome is associated with early vascular alterations, such as increased peripheral wave reflections and endothelial dysfunction, in untreated essential hypertensive patients. METHODS:...

journal_title：Journal of hypertension

authors： Plantinga Y,Ghiadoni L,Magagna A,Giannarelli C,Penno G,Pucci L,Taddei S,Del Prato S,Salvetti A

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:Cardiac hypertrophy arises as an adaptive response to increased afterload. Studies in knockout mice have shown that catecholamines, but not alpha1-adrenergic receptors, are necessary for such an adaptation to occur. However, whether beta-adrenergic receptors are critical for the development of cardiac hypertr...

journal_title：Journal of hypertension

authors： Palazzesi S,Musumeci M,Catalano L,Patrizio M,Stati T,Michienzi S,Di Certo MG,Mattei E,Vitelli L,Marano G

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Recent studies indicated that central SBP could be estimated by radial late-SBP (rSBP2) with a small disparity. However, most of these studies were conducted by SphygmoCor with a transfer function. The agreement between rSBP2 and central SBP was also tested in several invasive studies, but with inconsistent ...

journal_title：Journal of hypertension

authors： Zhang Y,Agnoletti D,Protogerou AD,Wang JG,Topouchian J,Salvi P,Safar ME,Blacher J

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Salt sensitivity and the magnitude of systolic blood pressure have been linked to haptoglobin (Hp) polymorphism in normotensives. The aim of the present study was to investigate the indices of hypertension, the severity of complications and the occurrence of coronary and peripheral artery disease for the vari...

journal_title：Journal of hypertension

authors： Delanghe JR,Duprez DA,De Buyzere ML,Bergez BM,Callens BY,Leroux-Roels GG,Clement DL

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:Inflammation is necessary for successful pregnancy; however, excessive inflammation plays a central role in the development of the pregnancy-specific hypertensive disorder preeclampsia. Numerous anti-inflammatory cytokines are decreased in women with preeclampsia but the role of individual cytokines in blood ...

journal_title：Journal of hypertension

authors： Chatterjee P,Kopriva SE,Chiasson VL,Young KJ,Tobin RP,Newell-Rogers K,Mitchell BM

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To assess the diagnostic accuracy of recommendations for self-monitoring blood pressure (BP) for diagnosing hypertension in primary care. METHODS:Two hundred and forty-seven consecutive participants with raised (≥130 mmHg systolic) BP measured by their general practitioner from four primary care practices in...

journal_title：Journal of hypertension

authors： Nunan D,Thompson M,Heneghan CJ,Perera R,McManus RJ,Ward A

更新日期：2015-04-01 00:00:00

abstract：AIMS:The addition of an aldosterone receptor antagonist on top of current optimal therapy (based on angiotensin II inhibition) has demonstrated an important clinical benefit in heart failure patients with systolic dysfunction. Whether this finding also applies to heart failure patients with preserved systolic function ...

journal_title：Journal of hypertension

authors： Muñoz-Pacheco P,Ortega-Hernández A,Caro-Vadillo A,Casanueva-Eliceiry S,Aragoncillo P,Egido J,Fernández-Cruz A,Gómez-Garre D

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To investigate gender-dependent difference in the free cytosolic calcium concentration ([Ca2+ ]i ) response to angiotensin II (Ang II) in vascular smooth muscle cells (VSMC) isolated from spontaneously hypertensive rats (SHR). To further evaluate this gender-dependent difference by studying the role of thapsi...

journal_title：Journal of hypertension

authors： Loukotová J,Kunes J,Zicha J

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:To find an objective, sensitive method for quantifying microvascular alterations associated with level of blood pressure and age. DESIGN:A prospective cross-sectional study. SUBJECTS AND METHODS:Seventy-four previously untreated hypertensive patients, referred to a hospital outpatients department, and 26 no...

journal_title：Journal of hypertension

authors： Stanton AV,Mullaney P,Mee F,O'Brien ET,O'Malley K

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:To determine the benefits and risks of drinking alcohol in treated hypertensives. DESIGN:A prospective study of 6,369 hypertensives (3,161 men) attending primarily hospital clinics in the UK. METHODS:Relative risks both for drinkers compared with non-drinkers and for level of alcohol consumption were calcul...

journal_title：Journal of hypertension

authors： Palmer AJ,Fletcher AE,Bulpitt CJ,Beevers DG,Coles EC,Ledingham JG,Petrie JC,Webster J,Dollery CT

更新日期：1995-09-01 00:00:00

abstract：:Carvedilol (BM 14190) is a new antihypertensive compound which combines beta-adrenoceptor blocking and precapillary vasodilating properties but is devoid of intrinsic sympathomimetic activity. The acute and long-term effects on blood pressure and regional haemodynamics (forearm plethysmography) were studied with carve...

journal_title：Journal of hypertension

authors： Eggertsen R,Sivertsson R,Andrén L,Hansson L

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVES:To investigate whether combined treatment with lisinopril, an angiotensin-converting enzyme (ACE) inhibitor and exercise training would have an additive effect in enhancing the capillary supply of the left ventricular (LV) myocardium in spontaneously hypertensive rats (SHR). DESIGN:Twelve-week-old male SHR ...

journal_title：Journal of hypertension

authors： Ziada AM,Hassan MO,Tahlilkar KI,Inuwa IM

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:Arterial remodeling aims to maintain a constant circumferential wall stress (sigmac). A failing remodeling process is associated with stroke. Data on the relationship between chronic kidney disease and arterial remodeling are scarce. METHODS:We investigated the association between a lower glomerular filtrati...

journal_title：Journal of hypertension

authors： Hermans MM,Henry RM,Dekker JM,Nijpels G,Heine RJ,Stehouwer CD

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:Reversibility of the systemic and renal alterations induced by N(omega)-nitro-L-arginine-methyl ester(L-NAME) was assessed by treatment with irbesartan and enalapril (30 and 10 mg/kg per 24 h, respectively) alone or in combination. DESIGN:L-NAME (20 mg/kg per 24 h) was given to rats for 6 weeks and treatment...

journal_title：Journal of hypertension

authors： Jover B,Herizi A,Casellas D,Mimran A

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:Studies of experimental animals show glomerular hypertension to be important in the progression of glomerular disease. We evaluated this connection clinically by examining the relationship between glomerular hemodynamics and histological changes in patients with immunoglobulin (Ig)A nephropathy. METHODS:The ...

journal_title：Journal of hypertension

authors： Konishi Y,Imanishi M,Okamura M,Yoshioka K,Okumura M,Okada N,Tanaka S,Fujii S,Kimura G

更新日期：2000-01-01 00:00:00

abstract：:Hypertension in children and adolescents has gained ground in cardiovascular medicine, thanks to the progress made in several areas of pathophysiological and clinical research. These guidelines represent a consensus among specialists involved in the detection and control of high blood pressure in children and adolesce...

journal_title：Journal of hypertension

authors： Lurbe E,Cifkova R,Cruickshank JK,Dillon MJ,Ferreira I,Invitti C,Kuznetsova T,Laurent S,Mancia G,Morales-Olivas F,Rascher W,Redon J,Schaefer F,Seeman T,Stergiou G,Wühl E,Zanchetti A,European Society of Hypertension.

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:This study tests the hypothesis that the transient receptor potential vanilloid subtype 1 channel induced neuropeptide secretion and depressor response are mediated by, at least in part, activation of endoplasmic reticulum associated Ca release receptors, leading to increased cytosolic Ca in dorsal root gangl...

journal_title：Journal of hypertension

authors： Huang W,Wang H,Galligan JJ,Wang DH

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:We have previously shown that conduit arteries of normotensive (WKY) and hypertensive (SHR) Japanese rats differ from normotensive (LN) and hypertensive (LH) Lyon rats in terms of lower aortic thickness and higher collagen III content, whereas differences in vasoactive properties are unknown. METHODS:Aortic ...

journal_title：Journal of hypertension

authors： Chamiot-Clerc P,Legrand M,Sassard J,Safar ME,Renaud JF

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to examine the utility of the generalized transfer function (GTF) and the late systolic shoulder of the radial pressure waveform (SBP2) for estimating seated central systolic blood pressure (c-SBP) and seated c-augmentation index (c-AIx). METHODS:In 199 participants (182 cardiovasc...

journal_title：Journal of hypertension

authors： Hirata K,Kojima I,Momomura S

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To examine in older individuals at high cardiovascular risk whether following a Mediterranean diet decreased the necessity of antihypertensive drugs and modulated their associated cardiovascular risk. METHODS:In the PREvención con DIeta MEDiterránea study, we assessed whether volunteers randomly allocated to...

journal_title：Journal of hypertension

authors： Ribó-Coll M,Lassale C,Sacanella E,Ros E,Toledo E,Sorlí JV,Babio N,Lapetra J,Gómez-Gracia E,Alonso-Gómez ÁM,Fiol M,Serra-Majem L,Pinto X,Castañer O,Díez-Espino J,González JI,Becerra-Tomás N,Cofán M,Díaz-López A,Estru

更新日期：2021-01-25 00:00:00

abstract：OBJECTIVE:To measure blood pressure accurately, by developing a new algorithm and an indirect method employing a non-elastic cuff with a photosensor. DESIGN AND METHODS:A non-elastic cuff was wrapped around the brachium. A reflecting plate (10 mm x 40 mm) was sited on the inner central part of the cuff on the arterial...

journal_title：Journal of hypertension

authors： Tochikubo O,Kawano Y,Miyajima E,Ishii M

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:Adults with obesity or obesity-related type 2 diabetes (T2DM) are at higher risk for cardiovascular disease possibly due to increased arterial stiffness. We sought to determine if arterial stiffness is increased in youth with obesity or T2DM as compared with lean controls. METHODS:Youth age 10-24 years (N = ...

journal_title：Journal of hypertension

authors： Urbina EM,Kimball TR,Khoury PR,Daniels SR,Dolan LM

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:The relationship between sodium intake and cardiovascular events is controversial, but most large epidemiological studies estimated sodium intake using formulae based on single urine samples, the validity of which is debated. We evaluated sodium intake estimating formulae in a large cohort of adult patients. ...

journal_title：Journal of hypertension

authors： Vidal-Petiot E,Joseph A,Resche-Rigon M,Boutten A,Mullaert J,d' Ortho MP,Vrtovsnik F,Steg PG,Flamant M

更新日期：2018-04-01 00:00:00