Gender-dependent difference in cell calcium handling in VSMC isolated from SHR: the effect of angiotensin II.

abstract：OBJECTIVE:Studies of experimental animals show glomerular hypertension to be important in the progression of glomerular disease. We evaluated this connection clinically by examining the relationship between glomerular hemodynamics and histological changes in patients with immunoglobulin (Ig)A nephropathy. METHODS:The ...

journal_title：Journal of hypertension

authors： Konishi Y,Imanishi M,Okamura M,Yoshioka K,Okumura M,Okada N,Tanaka S,Fujii S,Kimura G

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To determine the degree to which hypertension is a risk factor for macrovascular and microvascular complications in type 2 diabetes. DESIGN:Observational prospective study. SUBJECTS:Newly diagnosed Type 2 diabetic patients recruited into the UK Prospective Diabetes Study (n = 3648; mean age 52 years), 40% o...

journal_title：Journal of hypertension

authors：

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVE:Despite the widespread use of multivitamin supplements, little is known regarding their effects on blood pressure (BP) and the development of hypertension. We, therefore, sought to prospectively investigate how multivitamin use was associated with incident hypertension among middle-aged and older women. METH...

journal_title：Journal of hypertension

authors： Rautiainen S,Wang L,Lee IM,Manson JE,Gaziano JM,Buring JE,Sesso HD

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) has several negative effects on the heart including increase in myocardial end-systolic stress, venous return and sympathetic activity, all potential stimuli of left ventricular (LV) hypertrophy. The impact of the severity of OSA on LV geometry is unknown. We hypothesized that O...

journal_title：Journal of hypertension

authors： Cioffi G,Russo TE,Stefenelli C,Selmi A,Furlanello F,Cramariuc D,Gerdts E,de Simone G

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Construction of prognostically relevant endpoints for clinical trials in hypertension has increasingly included coronary revascularization with myocardial infarction (MI) as manifestations of coronary artery disease. However, whether coronary revascularization and MI predict other cardiovascular events simila...

journal_title：Journal of hypertension

authors： Cicala S,de Simone G,Gerdts E,Dahlöf B,Lindholm LH,Kjeldsen SE,Devereux RB

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Epidemiological studies suggest that intrauterine growth restriction (IUGR) due to maternal undernutrition during pregnancy represents a major risk factor for hypertension and diabetes in adult age. However, placental insufficiency, rather than maternal malnutrition, is the main cause of IUGR in the Western w...

journal_title：Journal of hypertension

authors： Jansson T,Lambert GW

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVES:Several studies have suggested a positive association between serum lipid levels and blood pressure (BP). This study investigated this association in a large population from 12 European countries. METHODS:Data were taken from the European Study on Cardiovascular Risk Prevention and Management in Usual Daily...

journal_title：Journal of hypertension

authors： Borghi C,Rodriguez-Artalejo F,De Backer G,Dallongeville J,Medina J,Guallar E,Perk J,Banegas JR,Tubach F,Roy C,Halcox JP

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:In short-term feeding trials, replacement of other macronutrients with monounsaturated fatty acid reduces blood pressure. However, observational studies have not clearly demonstrated a relationship between monounsaturated fatty acid intake and blood pressure. We report associations of monounsaturated fatty ac...

journal_title：Journal of hypertension

authors： Miura K,Stamler J,Brown IJ,Ueshima H,Nakagawa H,Sakurai M,Chan Q,Appel LJ,Okayama A,Okuda N,Curb JD,Rodriguez BL,Robertson C,Zhao L,Elliott P,INTERMAP Research Group.

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Type 2 diabetes mellitus is associated with an increased risk of hypertension, and cardiovascular and renal disease, and it has been recommended that management of hypertension should be more aggressive in presence than in absence of diabetes mellitus, but the matter is controversial at present. OBJECTIVES:...

journal_title：Journal of hypertension

authors： Thomopoulos C,Parati G,Zanchetti A

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Sitagliptin, a new antidiabetic drug that inhibits dipeptidyl peptidase (DPP)-4 enzyme activity, has been reported to possess neuroprotective property. We tested the protective effects of sitagliptin against chronic cerebral hypoperfusion (CHP) in mice after bilateral carotid artery stenosis (BCAS). METHOD:...

journal_title：Journal of hypertension

authors： Tsai TH,Sun CK,Su CH,Sung PH,Chua S,Zhen YY,Leu S,Chang HW,Yang JL,Yip HK

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:The platelet GPIIIa plays a pivotal role in platelet aggregation. Previous studies showed an association between the GPIIIa Pl(A1/A2) polymorphism and coronary thrombosis, while there is only contrasting evidence about its role in stroke. We explored the possibility that this polymorphism represents a risk fa...

journal_title：Journal of hypertension

authors： Lanni F,Santulli G,Izzo R,Rubattu S,Zanda B,Volpe M,Iaccarino G,Trimarco B

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:Microalbuminuria (MA) is a marker of adverse outcome in hypertension. The aim of this study was to investigate the association of MA with cardiovascular risk factors and glomerular hyperfiltration in the early stage of hypertension and to assess its predictive value for the development of sustained hypertensi...

journal_title：Journal of hypertension

authors： Palatini P,Mormino P,Mos L,Mazzer A,Dorigatti F,Zanata G,Longo D,Garbelotto R,De Toni R,Graniero G,Pessina AC,HARVEST Study Group.

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Although the benefit of hypertension treatment is well established in high-risk patients, there is a paucity of evidence regarding the benefit of treatment in patients with uncomplicated hypertension. METHODS:Hypertensive adult patients were selected from the Korea National Health Insurance Sample Cohort in...

journal_title：Journal of hypertension

authors： Lee CJ,Hwang J,Oh J,Lee SH,Kang SM,Choi D,Kim HC,Park S

更新日期：2017-05-01 00:00:00

abstract：:Ischemic renal disease (IRD) is defined as a clinically important reduction in glomerular filtration rate or loss of renal parenchyma caused by hemodynamically significant renal artery stenosis. IRD is a common and often overlooked clinical entity that presents itself in the setting of extrarenal arteriosclerotic vasc...

journal_title：Journal of hypertension

authors： Preston RA,Epstein M

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVES:To investigate whether the combination of exercise training with the angiotensin-converting enzyme inhibitor lisinopril will have an additional beneficial effect on left ventricular function in spontaneously hypertensive rats. DESIGN:Twelve-week-old male rats were assigned to treadmill running (Ht-Ex; 20 m/...

journal_title：Journal of hypertension

authors： Ziada AM

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to estimate the prevalence and risk factors of prehypertension (Pre-HTN) and hypertension (HTN) among the adult population of Iran. METHODS:A nationwide cross-sectional survey was conducted from December 2004 to February 2005. The selection was conducted by stratified probability cl...

journal_title：Journal of hypertension

authors： Janghorbani M,Amini M,Gouya MM,Delavari A,Alikhani S,Mahdavi A

更新日期：2008-03-01 00:00:00

abstract：:Uptake of 45Ca was measured in rings of thoracic aorta from rabbits with hypertension, induced by cellophane perinephritis (Page hypertension: one-kidney, one wrap). Basal 45Ca uptake was increased significantly in the hypertensive group (sham: 100 +/- 3, hypertensive: 133 +/- 11 nmol/g wet weight, n = 6). 45Ca uptake...

journal_title：Journal of hypertension

authors： Dong Y,Wadsworth RM

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVES:We examined whether the Rho/Rho-kinase pathway is involved in the pathogenesis of nephrosclerosis in severely hypertensive rats and assessed the effects of long-term treatment with a Rho-kinase inhibitor, fasudil, on kidney function, histological findings, gene expressions, and survival. We also attempted to...

journal_title：Journal of hypertension

authors： Nishikimi T,Koshikawa S,Ishikawa Y,Akimoto K,Inaba C,Ishimura K,Ono H,Matsuoka H

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:The relation of noninvasive vascular function to sex, sex hormones, and reproductive history in the general population is little understood. METHODS:We simultaneously assessed flow-mediated dilation (FMD) and peripheral arterial tonometry in 454 women (mean age 40.4±16.1 years, age range 19-78 years) and 100...

journal_title：Journal of hypertension

authors： Schnabel RB,Biener MP,Wilde S,Sinning CR,Ojeda FM,Zeller T,Lubos E,Lackner KJ,Warnholtz A,Gori T,Espinola-Klein C,Blankenberg S,Munzel T,Wild PS

更新日期：2013-07-01 00:00:00

abstract：:Isolated tail arteries from stroke-prone spontaneously hypertensive rats (SHRSP), but not from normotensive Wistar-Kyoto rats (WKY), exhibit oscillatory contractions in response to norepinephrine. Previous studies indicate that the mechanism for these oscillations involves altered membrane calcium and/or potassium han...

journal_title：Journal of hypertension

authors： Bruner CA,Webb RC

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The difference between clinic and ambulatory blood pressure (BP) is a poor estimate of the true white-coat effect (WCE) measured with beat-to-beat recording. METHOD:We investigated whether the difference between clinic and home BP (home WCE) was a better estimate of true WCE than ambulatory WCE. In 73 young...

journal_title：Journal of hypertension

authors： Saladini F,Benetti E,Malipiero G,Casiglia E,Palatini P

更新日期：2012-11-01 00:00:00

abstract：:The response of blood pressure, heart rate and plasma catecholamines to a mental arithmetic and a cold pressor test was studied in 70 patients with mild essential hypertension and in 41 age- and sex-matched normotensives. Each group consisted of three prospectively stratified age classes: 20-29, 30-39 and 40-55 years....

journal_title：Journal of hypertension

authors： Lenders JW,Willemsen JJ,de Boo T,Lemmens WA,Thien T

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVES:Increased central artery stiffness associates with cardiovascular disease. Among other factors, hypertension and aging are strong contributors to central artery stiffening, yet it has been difficult to separate their effects. Herein, we study isolated and combined effects of hypertension and aging on central...

journal_title：Journal of hypertension

authors： Spronck B,Ferruzzi J,Bellini C,Caulk AW,Murtada SI,Humphrey JD

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:Cardiovascular risk prediction is deemed fundamental and the assessment of organ damage is emerging as a potentially 'downstream' picture of individual risk. Our aim was to assess the feasibility and value of prediction of coronaropathy [coronary artery disease (CAD)] of integrated cardiovascular ultrasound e...

journal_title：Journal of hypertension

authors： Moreo A,Gaibazzi N,Faggiano P,Mohammed M,Carerj S,Mureddu G,Pigazzani F,Muiesan L,Salvetti M,Cesana F,Faden G,Facchetti R,Giannattasio C,Rigo F

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:As a new category of blood pressure (BP) classification according to the Seventh Report of The Joint National Committee, prehypertension has aroused people's great concern in recent years due to its associations with increased incidence of cardiovascular disease. However, there is little information about th...

journal_title：Journal of hypertension

authors： Dong GH,Wang D,Liu MM,Liu YQ,Zhao Y,Yang M,Meng XJ,Tian S,Meng X,Zhang HY

更新日期：2012-03-01 00:00:00

abstract：AIM:Since canine hereditary essential hypertension has been previously reported in a colony of Siberian husky dogs, we tested the suitability of this model for use in studies on the platelet defect identified in humans with essential hypertension. METHODS:Platelet aggregation and dense granule ATP secretion were measu...

journal_title：Journal of hypertension

authors： Thomas JS,McConnell MF,Bell TG,Padgett GA

更新日期：1992-12-01 00:00:00

abstract：OBJECTIVE:We have previously reported that hearts from N-[omega]-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive rats exhibited an enhanced expression of Gi proteins. Since, losartan, an AT1 receptor antagonist, has been shown to attenuate the L-NAME-induced increase in blood pressure, we undertook the pres...

journal_title：Journal of hypertension

authors： Hashim S,Anand-Srivastava MB

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to examine the utility of the generalized transfer function (GTF) and the late systolic shoulder of the radial pressure waveform (SBP2) for estimating seated central systolic blood pressure (c-SBP) and seated c-augmentation index (c-AIx). METHODS:In 199 participants (182 cardiovasc...

journal_title：Journal of hypertension

authors： Hirata K,Kojima I,Momomura S

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVES:To determine the prevalence and treatment status of hypertension in South Africa. DESIGN:National cross-sectional survey. SETTING:13 802 randomly selected South Africans, 15 years and older, were visited in their homes in 1998. METHODS:Trained fieldworkers completed questionnaires on lifestyle and chronic...

journal_title：Journal of hypertension

authors： Steyn K,Gaziano TA,Bradshaw D,Laubscher R,Fourie J,South African Demographic and Health Coordinating Team.

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:To assess cardiac function, myocardial mechanoenergetic efficiency (MEE), and ventricular-arterial coupling (VAC) longitudinally during normal pregnancy, and to study if there was an association between cardiac structure and function, and fetal growth. METHODS:Cardiac structure and function, MEE, and ventric...

journal_title：Journal of hypertension

authors： Iacobaeus C,Andolf E,Thorsell M,Bremme K,Östlund E,Kahan T

更新日期：2018-04-01 00:00:00