Cardiac function, myocardial mechano-energetic efficiency, and ventricular-arterial coupling in normal pregnancy.

abstract：OBJECTIVE:Arterial remodeling aims to maintain a constant circumferential wall stress (sigmac). A failing remodeling process is associated with stroke. Data on the relationship between chronic kidney disease and arterial remodeling are scarce. METHODS:We investigated the association between a lower glomerular filtrati...

journal_title：Journal of hypertension

authors： Hermans MM,Henry RM,Dekker JM,Nijpels G,Heine RJ,Stehouwer CD

更新日期：2008-04-01 00:00:00

abstract：:The effects of rilmenidine [(N-dicyclopropylmethyl) amino-2-oxazoline; S 3341], an alpha 2 agonist, on the hypertensive rat heart have been compared with those of propranolol, using a model of deoxycorticosterone acetate (DOCA)-salt hypertension. One week after nephrectomy and initial treatment with DOCA-salt, which w...

journal_title：Journal of hypertension

authors： Callens-el Amrani F,Paolaggi F,Swynghedauw B

更新日期：1989-12-01 00:00:00

abstract：:Plasma atrial natriuretic peptide (ANP) concentrations were measured by both direct radio-immunoassay and with pre-extraction of the peptide from plasma using C18 reverse phase columns. Peptide concentrations were measured in normal subjects (including a group of eight volunteers who received an intravenous infusion o...

journal_title：Journal of hypertension

authors： Richards AM,Tonolo G,McIntyre GD,Leckie BJ,Robertson JI

更新日期：1987-04-01 00:00:00

abstract：OBJECTIVE:We aimed to test whether eight common recently identified single-nucleotide polymorphisms (SNPs), strongly associated with blood pressure (BP) in the population, also have impact on the degree of BP reduction by antihypertensive agents with different mechanisms. METHODS:In 3863 Swedish hypertensive patients,...

journal_title：Journal of hypertension

authors： Hamrefors V,Sjögren M,Almgren P,Wahlstrand B,Kjeldsen S,Hedner T,Melander O

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:Human adrenomedullin precursor is converted to glycine-extended adrenomedullin (AM-Gly), an intermediate inactive form of adrenomedullin. Subsequently, AM-Gly is converted to active form of mature adrenomedullin (AM-m). The aim of the present study was to investigate (i) whether sex or age influences plasma ...

journal_title：Journal of hypertension

authors： Nishikimi T,Horio T,Kohmoto Y,Yoshihara F,Nagaya N,Inenaga T,Saito M,Teranishi M,Nakamura M,Ohrui M,Kawano Y,Matsuo H,Ishimitsu T,Takishita S,Matsuoka H,Kangawa K

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Elevated plasma glucocorticoid level is an independent predictor of increased mortality risk in chronic heart failure, but local biosynthesis and pathophysiological roles of glucocorticoids in the heart remain unclear. METHODS:Dahl salt-sensitive rats on high-salt diet and mice with transthoracic aortic ban...

journal_title：Journal of hypertension

authors： Ohtani T,Mano T,Hikoso S,Sakata Y,Nishio M,Takeda Y,Otsu K,Miwa T,Masuyama T,Hori M,Yamamoto K

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVES:Remodeling of small resistance arteries is an early sign of target organ damage in hypertension. Peripheral capillary morphology abnormalities in hypertension are not well studied. The study objective was to determine whether altered capillary morphology is associated with SBP, DBP, or both in individuals wi...

journal_title：Journal of hypertension

authors： Cheng C,Daskalakis C,Falkner B

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To determine the plasma cofactor which is required by diuretics (hydrochlorothiazide, chlorthalidone, indapamide, and furosemide) for direct vasorelaxant effects in vitro. DESIGN:A randomized, double-blind, vehicle-control design was used to avoid experimenter bias. METHODS:We plotted concentration-response...

journal_title：Journal of hypertension

authors： Abrahams Z,Pang MY,Lam EK,Wright JM

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:We aimed to investigate associations of childhood pulse pressure (PP) and change in PP status with adult subclinical vascular damage. METHODS:Data were obtained from a population-based cohort of children aged 6-18 years started in 1987. The study constituted 1254 participants who were followed up in 2010-201...

journal_title：Journal of hypertension

authors： Hou D,Yan Y,Liu J,Zhao X,Cheng H,Mi J

更新日期：2018-08-01 00:00:00

abstract：:Hypertension was induced in marmosets by ligating the minor branch of one renal artery. The blood pressure (BP), measured by a tail-cuff method, increased to hypertensive levels within 4-5 weeks and the maximum increases occurred after 4-15 weeks (BP, mean +/- s.e.m. was 120 +/- 3 and 152 +/- 6 mmHg before and 10 week...

journal_title：Journal of hypertension

authors： Neisius D,Wood JM

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVE:To study the effect of oral magnesium supplementation on blood pressure, platelet aggregation and platelet calcium handling in deoxycorticosterone acetate (DOCA)-induced hypertension in rats. DESIGN AND METHODS:Rats were divided into four groups of 20 each. Drug treatments were given for a 6-week period. Con...

journal_title：Journal of hypertension

authors： Kh R,Khullar M,Kashyap M,Pandhi P,Uppal R

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND METHOD:This study evaluated the effects of a linear block strength training programme on the parameters of cardiac remodelling in spontaneously hypertensive rats. Thirty-nine rats were equally distributed in four groups: normotensive sedentary, normotensive trained, hypertensive sedentary and hypertensiv...

journal_title：Journal of hypertension

authors： Perilhão MS,Krause Neto W,da Silva AA,Alves LLS,Antonio EL,Medeiros A,Rica RL,Serra AJ,Tucci PJF,Bocalini DS

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Some patients with essential hypertension manifest greater than normal urinary excretion of albumin (UAE). Authors of a few retrospective studies have suggested that there is an association between microalbuminuria and cardiovascular risk. OBJECTIVE:To evaluate whether microalbuminuria is associated with a ...

journal_title：Journal of hypertension

authors： Bigazzi R,Bianchi S,Baldari D,Campese VM

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:C-reactive protein (CRP) both reflects and participates in inflammation, and its circulating concentration marks cardiovascular risk. Here we sought to understand the role of heredity in determining CRP secretion. METHODS:CRP, as well as multiple facets of the metabolic syndrome, were measured in a series o...

journal_title：Journal of hypertension

authors： Wessel J,Moratorio G,Rao F,Mahata M,Zhang L,Greene W,Rana BK,Kennedy BP,Khandrika S,Huang P,Lillie EO,Shih PA,Smith DW,Wen G,Hamilton BA,Ziegler MG,Witztum JL,Schork NJ,Schmid-Schönbein GW,O'Connor DT

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:Primary aldosteronism (PA) is characterized by the onset of both cardiac and gluco-metabolic alterations. The aim of this study was to evaluate the impact of aldosterone excess on the development of such complications, and the effects of surgical and pharmacological treatment on their long-term outcome. METH...

journal_title：Journal of hypertension

authors： Giacchetti G,Ronconi V,Turchi F,Agostinelli L,Mantero F,Rilli S,Boscaro M

更新日期：2007-01-01 00:00:00

abstract：:To determine the role of the parasympathetic system in the development of essential hypertension, the concentrations of acetylcholine (ACh) as a parasympathetic marker and norepinephrine (NE) as a sympathetic marker were measured simultaneously in the heart of spontaneously hypertensive rats (SHR) at 4, 10 and 27 week...

journal_title：Journal of hypertension

authors： Tsuboi H,Ohno O,Ogawa K,Ito T,Hashimoto H,Okumura K,Satake T

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVE:Circulating biomarkers of endothelial dysfunction and inflammation are elevated in late pregnancy in women with preeclampsia. We examined plasma levels of inflammatory cytokines and adhesion molecules in early pregnancy, to assess their ability to predict preeclampsia. METHODS:In a prospective longitudinal s...

journal_title：Journal of hypertension

authors： Carty DM,Anderson LA,Freeman DJ,Welsh PI,Brennand JE,Dominiczak AF,Delles C

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of hypertension and diabetes mellitus on vascular albumin permeability and hypertrophy in 11-week-old Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR) with and without 3 weeks of streptozotocin-induced diabetes. METHODS:Vascular albumin permeability was measured as...

journal_title：Journal of hypertension

authors： Hulthén UL,Rumble J,Cooper ME,Johnston CI

更新日期：1995-05-01 00:00:00

abstract：:The present study was designed to investigate in rats the influence of converting enzyme inhibition with captopril on blood pressure, plasma urea, plasma renin concentration (PRC), plasma aldosterone and plasma vasopressin, and to define the interrelationships between PRC and these variables during equal degrees of ei...

journal_title：Journal of hypertension

authors： Gardes J,Gonzalez MF,Corvol P,Ménard J

更新日期：1986-04-01 00:00:00

abstract：OBJECTIVES:Obstructive sleep apnoea (OSA) and hypertension frequently coexist, and both are associated with higher night-time than daytime urine sodium excretion rate (UNaV). However, the relative contribution of each condition is unknown. We compared the circadian pattern of UNaV in hypertensive and normotensive patie...

journal_title：Journal of hypertension

authors： White LH,Bradley TD,Logan AG

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:We assessed hypertension prevalence, blood pressure (BP)-lowering treatment and control in obese adults compared with lean/normal-weight individuals in France. METHODS:Multistage stratified random sample of 2075 adults from the French Nutrition and Health Survey (ENNS), a cross-sectional national survey carr...

journal_title：Journal of hypertension

authors： Czernichow S,Castetbon K,Salanave B,Vernay M,Barry Y,Batty GD,Hercberg S,Blacher J

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The usefulness of the hypertensive retinopathy classification by Keith-Wagener-Barker (KWB) in clinical practice remains controversial. The simplified Mitchell-Wong grading, combining the two initial KWB' grades in one stage, is proposed as an alternative method; both systems are poorly validated regarding t...

journal_title：Journal of hypertension

authors： Aissopou EK,Papathanassiou M,Nasothimiou EG,Konstantonis GD,Tentolouris N,Theodossiadis PG,Papaioannou TG,Sfikakis PP,Protogerou AD

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVES:Recent studies in homogenized hearts suggest that chymase rather than angiotensin converting enzyme (ACE) is responsible for cardiac angiotensin I to angiotensin II conversion. We investigated in intact rat hearts whether (i) enzymes other than ACE contribute to angiotensin I to angiotensin II conversion and...

journal_title：Journal of hypertension

authors： de Lannoy LM,Schuijt MP,Saxena PR,Schalekamp MA,Danser AH

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVES:Genetically hypertensive rats provide an excellent model to investigate the genetic mechanisms of hypertension. We previously identified three differentially expressed genes, Acadsb (short/branched chain acyl-CoA dehydrogenase), Comt (catecholamine-O-methyltransferase), and Pnpo (pyridoxine 5'-phosphate oxid...

journal_title：Journal of hypertension

authors： Kamide K,Kokubo Y,Yang J,Matayoshi T,Inamoto N,Takiuchi S,Horio T,Miwa Y,Yoshii M,Tomoike H,Tanaka C,Banno M,Okuda T,Kawano Y,Miyata T

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To determine whether acutely lowering insulin levels with somatostatin in obese, insulin-resistant hypertensive individuals reduces arterial pressure and forearm vascular resistance; and whether these changes are reversed by restoring insulin levels during continuing somatostatin infusion. SUBJECTS:Subjects ...

journal_title：Journal of hypertension

authors： Gudbjörnsdottir S,Elam M,Sellgren J,Anderson EA

更新日期：1996-01-01 00:00:00

abstract：:: Altered blood pressure (BP) is a common phenomenon in acute ischemic stroke (AIS), with high BP being the most frequent scenario. The pathophysiology of BP changes in AIS is complex and only partially understood. The available evidence indicates that extremely high BP during AIS is associated with a poor outcome. Im...

journal_title：Journal of hypertension

authors： Gąsecki D,Coca A,Cunha P,Hering D,Manios E,Lovic D,Zaninelli A,Sierra C,Kwarciany M,Narkiewicz K,Karaszewski B

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Oxidant stress is implicated in the pathogenesis of atherosclerosis in cardiovascular diseases. Our aim was to test oxidative stress, as 8-iso-prostaglandin F2alpha (8-iso-PGF2alpha), and its relationship with inflammation markers C-reactive protein (CRP) and tumour necrosis factor-alpha (TNFalpha), and endo...

journal_title：Journal of hypertension

authors： Cottone S,Mulè G,Nardi E,Vadalà A,Lorito MC,Guarneri M,Arsena R,Palermo A,Cerasola G

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:A reduced cardiac output in chronic heart failure (CHF) evokes renal NaCl and water retention, and, therefore, activates mechanisms promoting natriuresis. Atrial natriuretic peptide (ANP) is one such factor. We hypothesized that another NaCl sensitive endogenous natriuretic factor, i.e., marinobufagenin (MBG...

journal_title：Journal of hypertension

authors： Fridman AI,Matveev SA,Agalakova NI,Fedorova OV,Lakatta EG,Bagrov AY

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVES:Advanced diabetic nephropathy (DN) is characterized by a marked development of cardiovascular and renal disease. These patients are frequently managed by different health professionals with the consequence that the quality of care may differ substantially. To compare the management of cardiovascular risk fac...

journal_title：Journal of hypertension

authors： Minutolo R,Sasso FC,Chiodini P,Cianciaruso B,Carbonara O,Zamboli P,Tirino G,Pota A,Torella R,Conte G,De Nicola L

更新日期：2006-08-01 00:00:00

abstract：AIM:The aim of this study was to assess the prevalence of ascending aortic dilatation and to evaluate the possible association between proximal aorta dilatation and structural or functional markers of cardiac organ damage in hypertensive patients. BACKGROUND:Dilatation of the sinus of valsalva (SoV) is a common findin...

journal_title：Journal of hypertension

authors： Milan A,Degli Esposti D,Salvetti M,Izzo R,Moreo A,Pucci G,Bruno G,Pareo I,Parini A,Paini A,Laurino FI,Sormani P,Sgariglia R,Avenatti E,De Luca N,Working Group on Heart and Hypertension of the Italian Society of Hypertension

更新日期：2019-01-01 00:00:00