Remodelling of the heart in DOCA-salt hypertensive rats by propranolol and by an alpha-2 agonist, rilmenidine.

abstract：OBJECTIVE:Abnormal vascular reactivity contributes to the pathophysiology of hypertension and hypertension-related organ damage. As the dietary content of fatty acids may affect the vascular responses, we investigated the relationship of endothelium-independent and endothelium-dependent vasodilation with the fatty acid...

journal_title：Journal of hypertension

authors： Colussi G,Catena C,Dialti V,Mos L,Sechi LA

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:High sodium intake is associated with increased risk of end-organ damage, independent of blood pressure (BP) levels. The protective peptide adiponectin may play a role in the pathogenesis of hypertension and particularly in salt-loaded conditions. Furthermore, increased adiponectin levels were observed in sa...

journal_title：Journal of hypertension

authors： Kamari Y,Shimoni N,Koren F,Peleg E,Sharabi Y,Grossman E

更新日期：2010-01-01 00:00:00

abstract：:The haemodynamic effects associated with the onset of hypertension induced by infusion of adrenocorticotrophin (ACTH) were investigated in sheep. Analysis of haemodynamic data collected over 24 h by a computer-based monitoring system revealed that mean arterial pressure (MAP) was significantly increased after 4 h. Car...

journal_title：Journal of hypertension

authors： Spence CD,Brown A,Coghlan JP,Parkes DG,Whitworth JA,Scoggins BA

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:Recently, an expert group advised to measure carotid-femoral (cf) pulse wave velocity (PWV) on the right side of the body, and to use a sliding caliper when tape measure distance cannot be obtained in a straight line. The present study investigates the evidence for this advice by comparing the real travelled...

journal_title：Journal of hypertension

authors： Bossuyt J,Van De Velde S,Azermai M,Vermeersch SJ,De Backer TL,Devos DG,Heyse C,Filipovsky J,Segers P,Van Bortel LM

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:There is ongoing discussion on how best to screen for diabetes mellitus. Previous studies suggest that an abnormal oral glucose tolerance test (OGTT) is better than fasting glucose levels in predicting cardiovascular mortality, which is largely determined by macrovascular complications in type 2 diabetes. We ...

journal_title：Journal of hypertension

authors： Schneider MP,Ott C,Ritt M,Raff U,Schlaich MP,Schmieder RE

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Hypertension and fractures related to osteoporosis are major public health problems that often coexist. This study examined the associations between exposure to different antihypertensive drug classes and the risk of hip fracture in hypertensive patients. METHOD:We included 59 246 individuals, 50 years and o...

journal_title：Journal of hypertension

authors： Bokrantz T,Schiöler L,Boström KB,Kahan T,Mellström D,Ljungman C,Hjerpe P,Hasselström J,Manhem K

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Cathepsin L (CTSL1) catalyzes the formation of peptides that influence blood pressure (BP). Naturally occurring genetic variation or targeted ablation of the Ctsl1 locus in mice yield cardiovascular pathology. Here, we searched for genetic variation across the human CTSL1 locus and probed its functional effe...

journal_title：Journal of hypertension

authors： Mbewe-Campbell N,Wei Z,Zhang K,Friese RS,Mahata M,Schork AJ,Rao F,Chiron S,Biswas N,Kim HS,Mahata SK,Waalen J,Nievergelt CM,Hook VY,O'Connor DT

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:Nonsteroidal anti-inflammatory drugs vary in their impact on blood pressure and the effect of lumiracoxib 100 mg once daily has not been studied previously. To examine whether lumiracoxib 100 mg once daily would result in lower 24-h mean systolic ambulatory blood pressure than ibuprofen 600 mg three times da...

journal_title：Journal of hypertension

authors： MacDonald TM,Reginster JY,Littlejohn TW,Richard D,Lheritier K,Krammer G,Rebuli R

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:We tested the reproducibility of ambulatory blood pressure (ABP), BP variability, and BP reduction in hypertensive patients. METHODS:Forty-two hypertensive patients were enrolled, and ABP monitoring (ABPM) was performed four times in each patient: twice before and twice after the treatment. Morning BP was de...

journal_title：Journal of hypertension

authors： Eguchi K,Hoshide S,Hoshide Y,Ishikawa S,Shimada K,Kario K

更新日期：2010-05-01 00:00:00

abstract：:: The hypertension paradigm has contributed to a dramatic reduction in CVD mortality. This has been achieved by applying average results of population studies to identify a target population and design a common intervention to achieve a BP goal. Progressive lowering of the BP threshold has expanded the fraction of per...

journal_title：Journal of hypertension

authors： Alderman MH,Blumenfeld JD

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:Despite the widespread use of multivitamin supplements, little is known regarding their effects on blood pressure (BP) and the development of hypertension. We, therefore, sought to prospectively investigate how multivitamin use was associated with incident hypertension among middle-aged and older women. METH...

journal_title：Journal of hypertension

authors： Rautiainen S,Wang L,Lee IM,Manson JE,Gaziano JM,Buring JE,Sesso HD

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Nitric oxide is involved in the regulation of vascular basal tone and blood pressure. Polymorphisms of NOS3, the gene that codes for endothelial nitric oxide synthase, have been associated with essential hypertension. OBJECTIVE:To look for linkage and association of three di-allelic polymorphisms (Glu298Asp...

journal_title：Journal of hypertension

authors： Persu A,Vinck WJ,El Khattabi O,Janssen RG,Paulussen AD,Devuyst O,Vlietinck R,Fagard RH

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:We hypothesized that downregulation of the antioxidant thioredoxin system contributes to oxidative stress in angiotensin II-induced hypertension. As oestrogen may protect against oxidative stress, we also evaluated whether the thioredoxin system, particularly in the heart, is differentially regulated between ...

journal_title：Journal of hypertension

authors： Ebrahimian T,He Y,Schiffrin EL,Touyz RM

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:The upward trends in the prevalence and control of hypertension in Chinese adults have been described, but recent trends based on the most recent guidelines are unavailable. We examined recent trends in the prevalence, awareness, treatment and control of hypertension among Chinese adults from 1991 to 2015 bas...

journal_title：Journal of hypertension

authors： Ma S,Yang L,Zhao M,Magnussen CG,Xi B

更新日期：2020-11-11 00:00:00

abstract：BACKGROUND:Hypertension control is often inadequate in HIV patients. In a contemporary, nationwide cohort of Italian HIV-infected adults, we assessed time trends in hypertension prevalence, awareness, treatment, and control. We also evaluated predictors of cardiovascular events and of new-onset hypertension. METHODS:M...

journal_title：Journal of hypertension

authors： De Socio GV,Ricci E,Maggi P,Parruti G,Celesia BM,Orofino G,Madeddu G,Martinelli C,Menzaghi B,Taramasso L,Bonfanti P,Pucci G,Schillaci G,CISAI study group.

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Lacidipine is a widely used calcium-channel blocker, which has both long-lasting antihypertensive activity and also antioxidant properties. Previous studies have demonstrated the ability of lacidipine to reduce the development of atherosclerotic lesions in several animal models. OBJECTIVE:The present study ...

journal_title：Journal of hypertension

authors： Cristofori P,Lanzoni A,Quartaroli M,Pastorino AM,Zancanaro C,Cominacini L,Gaviraghi G,Turton J

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Mineralocorticoid receptor antagonists are increasingly used in patients with treatment-resistant hypertension (TRH). There is experimental evidence for blood pressure (BP) independent effects of mineralocorticoid receptor blockade on cardiovascular target organ damage. We hypothesized that low-dose eplereno...

journal_title：Journal of hypertension

authors： Schneider A,Schwab J,Karg MV,Kalizki T,Reinold A,Schneider MP,Schmieder RE,Schmidt BM

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:We assessed the prevalence and determinants of high blood pressure (BP), and barriers to diagnosis and treatment, in Dar es Salaam, Tanzania. METHODS:We surveyed and screened 2174 community-dwelling adults aged at least 40 years in 2014 and conducted a follow-up after 1 year. RESULTS:Median BP was 131/81 m...

journal_title：Journal of hypertension

authors： Zack RM,Irema K,Kazonda P,Leyna GH,Liu E,Spiegelman D,Fawzi W,Njelekela M,Killewo J,Danaei G

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:We investigated the contribution of reduced nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase-dependent reactive oxygen species (ROS) generation to the pathogenesis of diastolic heart failure (DHF) in Dahl salt-sensitive (DS) hypertensive rats, with the aim of testing our hypothesis that the cardiop...

journal_title：Journal of hypertension

authors： Guo P,Nishiyama A,Rahman M,Nagai Y,Noma T,Namba T,Ishizawa M,Murakami K,Miyatake A,Kimura S,Mizushige K,Abe Y,Ohmori K,Kohno M

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To examine the changes in plasma brain natriuretic peptide (BNP), atrial natriuretic peptide (ANP) and blood pressure in patients with essential hypertension on a low, normal and high sodium intake. DESIGN AND METHODS:Twelve patients with mild-to-moderate essential hypertension were studied. Plasma, urinary ...

journal_title：Journal of hypertension

authors： Buckley MG,Markandu ND,Sagnella GA,MacGregor GA

更新日期：1994-07-01 00:00:00

abstract：:The activity of renal Na-K-ATPase was compared in hypertension-prone (SBH) and hypertension-resistant (SBN) Sabra rats on regular sodium intake and 2-3 weeks after a high sodium diet. ATPase activity was determined in single nephron segments by a micromethod. The activity profile was found to be similar in the two sub...

journal_title：Journal of hypertension

authors： Doucet A,Mekler J,el Mernissi G,Ben-Ishay D

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVE:Anemia is common in patients with heart failure and several factors have been thought to cause anemia in heart failure. Despite vigorous studies, the mechanism underlying the pathophysiology of anemia in heart failure is unknown. We investigated the iron regulating system in Dahl salt-sensitive heart failure ...

journal_title：Journal of hypertension

authors： Naito Y,Tsujino T,Fujimori Y,Sawada H,Akahori H,Hirotani S,Ohyanagi M,Masuyama T

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Inherited differences in renal function underlie the effect of high salt diets on blood pressure in Dahl rats. We probed the kidneys of inbred Dahl SS/Jr and SR/Jr for anonymous and candidate genes whose expression was regulated by dietary sodium. METHODS:mRNA quantitation of both candidate genes implicated ...

journal_title：Journal of hypertension

authors： Lighthall GK,Hamilton BP,Hamlyn JM

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVES:Stroke is elevated in people of black African descent, but evidence for excess subclinical cerebrovascular disease is conflicting, and the role of risk factors in determining any ethnic differences observed unexplored. METHODS:We compared prevalence of brain infarcts, and severe white matter hyperintensitie...

journal_title：Journal of hypertension

authors： Shibata D,Tillin T,Beauchamp N,Heasman J,Hughes AD,Park C,Gedroyc W,Chaturvedi N

更新日期：2013-12-01 00:00:00

abstract：:Systolic (SBP), diastolic (DBP) and mean [MBP = diastolic + 1/3 (systolic - diastolic)] blood pressures were compared as predictors of all causes of death (ALL) and of deaths from atherosclerotic cardiovascular disease (ACVD) in 2480 men, aged 40-59 years, belonging to three cohorts followed up for 20 years. Both univ...

journal_title：Journal of hypertension

authors： Menotti A,Seccareccia F,Giampaoli S,Giuli B

更新日期：1989-07-01 00:00:00

abstract：:Adequate evaluation of automated sphygmomanometers, in terms of safety, accuracy, mechanical reliability, patient acceptability and ability to record ambulatory blood pressure is essential before these devices are used in clinical practice and in clinical trials. We have evaluated the accuracy and performance of the A...

journal_title：Journal of hypertension

authors： Jamieson MJ,Fowler G,MacDonald TM,Webster J,Witte K,Lawson L,Crichton W,Jeffers TA,Petrie JC

更新日期：1990-07-01 00:00:00

abstract：:Hypertensive disease is known to increase the risks in connection with acute changes in blood pressure due to the presence of pronounced structural as well as functional changes in the cardiovascular system. In the present study the metabolic consequences of fixed haemorrhagic hypotension [mean arterial pressure (MAP)...

journal_title：Journal of hypertension

authors： Wennberg E,Hagberg H,Haljamäe H,Johansson BB

更新日期：1983-10-01 00:00:00

abstract：OBJECTIVE:This study evaluated the impact of prolonged circulatory unloading and subsequent left ventricular (LV) mass decrease on LV myocardial performance. Five-week head-down tilt (-6°) bed rest (HDTBR) was used as a model of prolonged circulatory unloading. METHODS:Ten young healthy male volunteers (age 23 ± 2 yea...

journal_title：Journal of hypertension

authors： Kozàkovà M,Malshi E,Morizzo C,Pedri S,Santini F,Biolo G,Pagani M,Palombo C

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:Calcium blockade has been reported to inhibit the contraction of the vascular smooth muscle and the liberation of vasoactive substances by endothelial cells. We tested the effects of calcium blockade on the mechanical properties of the carotid artery in normotensive Wistar-Kyoto (WKY) rats and spontaneously ...

journal_title：Journal of hypertension

authors： Lévy BI,el Fertak L,Pieddeloup C,Barouki F,Safar ME

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence of hypertension and the rate of decline in renal function in a sample of 47 Olivetti Heart Study (OHS) participants whose blood pressure (BP) salt-sensitivity and renal tubular sodium handling had been assessed in 1987-88. METHODS:During the 2002-04 OHS follow-up examination, medica...

journal_title：Journal of hypertension

authors： Barba G,Galletti F,Cappuccio FP,Siani A,Venezia A,Versiero M,Della Valle E,Sorrentino P,Tarantino G,Farinaro E,Strazzullo P

更新日期：2007-07-01 00:00:00