Childhood pulse pressure predicts subclinical vascular damage in adulthood: the Beijing Blood Pressure Cohort Study.

Abstract:

OBJECTIVE:We aimed to investigate associations of childhood pulse pressure (PP) and change in PP status with adult subclinical vascular damage. METHODS:Data were obtained from a population-based cohort of children aged 6-18 years started in 1987. The study constituted 1254 participants who were followed up in 2010-2011 (aged 28-42 years). Carotid arteriosclerosis and aortic stiffness were assessed by carotid intima-media thickness (IMT) and brachial-ankle pulse wave velocity (PWV), respectively. RESULTS:Both childhood PP and mean arterial pressure (MAP) were independently associated with adult carotid IMT and PWV adjusted for sex, childhood age, follow-up duration, and other traditional cardiovascular risk factors. After further adjustment for adult values of PP and MAP, childhood PP was still associated with adult carotid IMT but not with PWV, whereas childhood MAP was associated with adult PWV but not with carotid IMT. In addition, compared with participants who had normal PP in both childhood and adulthood, participants who had high PP in adulthood, irrespective of their childhood PP status, had higher levels of carotid IMT and PWV (all P < 0.05). Participants who had high PP in childhood and normal PP in adulthood also had higher levels of adult carotid IMT but similar levels of PWV compared with participants who had consistently normal PP. CONCLUSION:Large PP in childhood plays an important role in the development of subclinical vascular damage in adulthood. These findings underscore the importance of early prevention of large PP to reduce future risk of cardiovascular disease.

journal_name

J Hypertens

journal_title

Journal of hypertension

authors

Hou D,Yan Y,Liu J,Zhao X,Cheng H,Mi J

doi

10.1097/HJH.0000000000001748

subject

Has Abstract

pub_date

2018-08-01 00:00:00

pages

1663-1670

issue

8

eissn

0263-6352

issn

1473-5598

journal_volume

36

pub_type

杂志文章
  • Albuminuria in normotensive and hypertensive individuals attending offices of general practitioners.

    abstract:OBJECTIVE:To investigate the rate of albumin excretion and the prevalence of albuminuria in hypertensive individuals relative to the normotensive population, and to clarify the quantitative importance of confounding variables. DESIGN AND METHODS:We examined the morning urines of all consecutive non-diabetic and diabet...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199605000-00016

    authors: Hörner D,Fliser D,Klimm HP,Ritz E

    更新日期:1996-05-01 00:00:00

  • Differential alterations of common carotid and femoral artery distensibility in 12-week-old spontaneously hypertensive rats.

    abstract:OBJECTIVE:In essential hypertension, the mechanical properties of the radial artery have been shown to be largely unaltered, whereas more controversial and less reliable data have been obtained for the common carotid artery. We therefore examined the distensibility/pressure relationships of the predominantly elastic co...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199715120-00070

    authors: Stella ML,Mircoli L,Mangoni AA,Giannattasio C,Ferrari AU,Mancia G

    更新日期:1997-12-01 00:00:00

  • Systemic and regional haemodynamic effects of renal denervation in spontaneously hypertensive rats.

    abstract::Systemic and regional haemodynamic effects of renal denervation were evaluated in adult (six-month-old) male spontaneously hypertensive rats (SHR) using the Fick procedure and electromagnetic flowmetry technique. Renal denervation (bilateral, 10% phenol in ethanol), performed five to eight days before the experiment, ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-198312000-00010

    authors: Lee JY,Walsh GM

    更新日期:1983-12-01 00:00:00

  • The predictive role of systolic, diastolic and mean blood pressures on cardiovascular and all causes of death.

    abstract::Systolic (SBP), diastolic (DBP) and mean [MBP = diastolic + 1/3 (systolic - diastolic)] blood pressures were compared as predictors of all causes of death (ALL) and of deaths from atherosclerotic cardiovascular disease (ACVD) in 2480 men, aged 40-59 years, belonging to three cohorts followed up for 20 years. Both univ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-198907000-00011

    authors: Menotti A,Seccareccia F,Giampaoli S,Giuli B

    更新日期:1989-07-01 00:00:00

  • What to do when faced with an unmeasurable ambulatory blood pressure?

    abstract::If ambulatory blood pressure measurement is not possible because the upper-arm circumference is so great that even the largest cuff provided with the monitor will not encircle the arm, satisfactory measurements can be obtained by applying a cuff to the forearm. ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e32834192ef

    authors: O'Brien E

    更新日期:2011-03-01 00:00:00

  • Parity as predictor of early hypertension during menopausal transition.

    abstract:OBJECTIVES:Studies regarding the effects of parity on blood pressure in later life produced conflicting results. The aim of our study is to analyse whether parity influences the prevalence of hypertension in perimenopausal and postmenopausal women. METHODS:One thousand perimenopausal and postmenopausal women (mean age...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e32835c1742

    authors: Giubertoni E,Bertelli L,Bartolacelli Y,Origliani G,Modena MG

    更新日期:2013-03-01 00:00:00

  • Renal protective effects of chronic exercise and antihypertensive therapy in hypertensive rats with chronic renal failure.

    abstract:OBJECTIVES:Patients with chronic renal failure are restricted to mild physical activity and tend to a lack of exercise. However, there have been few reports regarding the influence of chronic exercise on the progression of renal disease. Similarly, there are few animal models concerned with the effect of exercise train...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200110000-00024

    authors: Kohzuki M,Kamimoto M,Wu XM,Xu HL,Kawamura T,Mori N,Nagasaka M,Kurosawa H,Minami N,Kanazawa M,Saito T,Yoshida K

    更新日期:2001-10-01 00:00:00

  • Vasoactive effects of potassium in kidneys of hypertensive rats fed a high-potassium diet.

    abstract:DESIGN AND METHODS:Levels of dietary and serum potassium are thought to correlate inversely with vascular resistance and blood pressure. This study examined renal vascular resistance in perfused rat kidneys partially preconstricted with 10 micromol/ phenylephrine, quantifying changes in the resistance when levels of po...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199917100-00017

    authors: Murphy ME,Cohen DB

    更新日期:1999-10-01 00:00:00

  • Visit-to-visit (long-term) and ambulatory (short-term) blood pressure variability to predict mortality in an elderly hypertensive population.

    abstract:OBJECTIVES:To explore the association of different types of blood pressure (BP) variability measures estimated from either short-term ambulatory reading-to-reading or long-term clinic visit-to-visit BP records with long-term survival in an elderly treated hypertensive population. METHODS:A subset of patients (n = 508)...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000001652

    authors: Chowdhury EK,Wing LMH,Jennings GLR,Beilin LJ,Reid CM,ANBP2 Management Committee.

    更新日期:2018-05-01 00:00:00

  • Blood pressure variability increases with advancing chronic kidney disease stage: a cross-sectional analysis of 16 546 hypertensive patients.

    abstract:OBJECTIVE:Increased BP-variability predicts cardiovascular morbidity and mortality in hypertensives. This study aimed to examine short-term BP-variability according to renal function stage. METHODS:We included 16 546 patients [10 270 (62.1%) without/6276 (38.9%) with CKD Stage 1-5] from the Spanish Ambulatory-Blood-Pr...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000001670

    authors: Sarafidis PA,Ruilope LM,Loutradis C,Gorostidi M,de la Sierra A,de la Cruz JJ,Vinyoles E,Divisón-Garrote JA,Segura J,Banegas JR

    更新日期:2018-05-01 00:00:00

  • Effects of glucose and insulin on the development of oxidative stress and hypertension in animal models of type 1 and type 2 diabetes.

    abstract:OBJECTIVES:To investigate whether glucose or insulin is the cause of increases in oxidative stress and blood pressure in insulin-resistant animals, and to evaluate the effects of alpha-lipoic acid (LA) on the production of the superoxide anion (O2-) in the aorta and blood pressure elevations in various models of diabet...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/01.hjh.0000160215.78973.ba

    authors: El Midaoui A,de Champlain J

    更新日期:2005-03-01 00:00:00

  • Relationship between exercise systolic blood pressure and left ventricular geometry in overweight, mildly hypertensive patients.

    abstract:OBJECTIVE:To examine the association between the graded exercise systolic blood pressure (SBP) response and left ventricular (LV) geometric structure in patients with untreated mild hypertension. PARTICIPANTS:The study included 80 sedentary, overweight patients (43 female and 37 male) with unmedicated high normal bloo...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200402000-00026

    authors: Pierson LM,Bacon SL,Sherwood A,Hinderliter AL,Babyak M,Gullette EC,Waugh R,Blumenthal JA

    更新日期:2004-02-01 00:00:00

  • Low dose of telmisartan prevents ischemic brain damage with peroxisome proliferator-activated receptor-gamma activation in diabetic mice.

    abstract:BACKGROUND:Telmisartan is a unique AT1 receptor blocker with a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonistic action. Activation of PPAR-gamma could prevent inflammation and brain damage. METHOD:We investigated the beneficial effect of telmisartan on ischemic brain damage via PPAR-gamma activa...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e32833a551a

    authors: Iwanami J,Mogi M,Tsukuda K,Min LJ,Sakata A,Jing F,Iwai M,Horiuchi M

    更新日期:2010-08-01 00:00:00

  • Association between orthostatic hypotension and cardiovascular risk, cerebrovascular risk, cognitive decline and falls as well as overall mortality: a systematic review and meta-analysis.

    abstract:OBJECTIVE:Several studies have suggested that orthostatic hypotension may be an independent predictor of cardiovascular or cerebrovascular risk and all-cause mortality, particularly in a geriatric population. In 1996, a consensus defined orthostatic hypotension as a SBP fall at least 20 mmHg and/or a DBP fall at least ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/HJH.0000000000000235

    authors: Angelousi A,Girerd N,Benetos A,Frimat L,Gautier S,Weryha G,Boivin JM

    更新日期:2014-08-01 00:00:00

  • Superior hypertension control with betablockade in the European Sleep Apnea Database.

    abstract:AIMS:Arterial hypertension is highly prevalent and difficult to control in patients with obstructive sleep apnea (OSA). High sympathoadrenergic activity is a hallmark physiological phenomenon in OSA. We hypothesized that an antihypertensive drug with inhibitory properties on this activity, such as beta blockers (BBs), ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000002629

    authors: Svedmyr S,Hedner J,Zou D,Parati G,Ryan S,Hein H,Pepin JL,Tkáčová R,Marrone O,Schiza S,Basoglu OK,Grote L,European Sleep Apnea Database (ESADA) study group.

    更新日期:2021-02-01 00:00:00

  • The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension.

    abstract:OBJECTIVE:To investigate whether a dietary supplement of vitamin B6 could attenuate the elevation of systolic blood pressure (SBP) in Zucker obese or spontaneously hypertensive rats, or rats ingesting sucrose. METHODS:Zucker obese rats (fa/fa), Sprague-Dawley rats with sucrose-induced elevation of SBP, spontaneously h...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199603000-00013

    authors: Lal KJ,Dakshinamurti K,Thliveris J

    更新日期:1996-03-01 00:00:00

  • Characterization of inactive renin in mouse amniotic fluid.

    abstract::We have demonstrated high concentrations of inactive renin in mouse amniotic fluid compared with mouse plasma and other organs. Its molecular weight was similar to that of prorenin from the mouse submaxillary gland (42 000 daltons). The activated renin had a Km value of 1.48 greater than M which is identical to that o...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-198410000-00012

    authors: Jacobsen J,Poulsen K

    更新日期:1984-10-01 00:00:00

  • Mean blood pressure, pulse pressure and grade of hypertension in untreated hypertensive patients with sleep-related breathing disorder.

    abstract:OBJECTIVE:To test the hypothesis that sleep-related breathing disorder (SRBD) is associated with increasing severity of cardiovascular risk markers. DESIGN:A cross-sectional study of sleep laboratory patients. SETTING:University Hospital Sleep Disorders Centre. PATIENTS:We studied 591 patients referred for a sleep s...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200104000-00004

    authors: Grote L,Hedner J,Peter JH

    更新日期:2001-04-01 00:00:00

  • Long-term exercise training and angiotensin-converting enzyme inhibition differentially enhance myocardial capillarization in the spontaneously hypertensive rat.

    abstract:OBJECTIVES:To investigate whether combined treatment with lisinopril, an angiotensin-converting enzyme (ACE) inhibitor and exercise training would have an additive effect in enhancing the capillary supply of the left ventricular (LV) myocardium in spontaneously hypertensive rats (SHR). DESIGN:Twelve-week-old male SHR ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/01.hjh.0000170387.61579.ab

    authors: Ziada AM,Hassan MO,Tahlilkar KI,Inuwa IM

    更新日期:2005-06-01 00:00:00

  • The measurement of central noradrenergic activity in spontaneously hypertensive rats: a comparison of free 3,4-dihydroxyphenylethyleneglycol levels with FLA-63 induced noradrenaline depletion.

    abstract::Noradrenergic activity was measured in the brainstem, hypothalamus and thoracic spinal cord of male and female spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats at 6 and 28-36 weeks of age. Two techniques were used, measurement of a major noradrenaline (NA) metabolite, free 3,4-dihydroxyphenylethyleneglycol...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-198506000-00007

    authors: Howes LG,Summers RJ,Rowe PR,Louis WJ

    更新日期:1985-06-01 00:00:00

  • Increased arterial stiffness is found in adolescents with obesity or obesity-related type 2 diabetes mellitus.

    abstract:OBJECTIVE:Adults with obesity or obesity-related type 2 diabetes (T2DM) are at higher risk for cardiovascular disease possibly due to increased arterial stiffness. We sought to determine if arterial stiffness is increased in youth with obesity or T2DM as compared with lean controls. METHODS:Youth age 10-24 years (N = ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e32833a6132

    authors: Urbina EM,Kimball TR,Khoury PR,Daniels SR,Dolan LM

    更新日期:2010-08-01 00:00:00

  • Reproducibility of peripheral arterial tonometry for the assessment of endothelial function in adults.

    abstract:OBJECTIVES:Endothelial dysfunction is associated to cardiovascular risk factors and predicts cardiovascular events. Peripheral arterial tonometry (PAT) is a novel noninvasive method to assess endothelial function. However, there is a paucity of data about its reproducibility. The aim of this study was to assess the fea...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e328362d913

    authors: Brant LC,Barreto SM,Passos VM,Ribeiro AL

    更新日期:2013-10-01 00:00:00

  • Effect of self-measurement of blood pressure on adherence to treatment in patients with mild-to-moderate hypertension.

    abstract:BACKGROUND:Poor adherence to treatment is one of the major problems in the treatment of hypertension. Self blood pressure measurement may help patients to improve their adherence to treatment. METHOD:In this prospective, randomized, controlled study coordinated by a university hospital, a total of 228 mild-to-moderate...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/HJH.0b013e328334f36b

    authors: van Onzenoort HA,Verberk WJ,Kroon AA,Kessels AG,Nelemans PJ,van der Kuy PH,Neef C,de Leeuw PW

    更新日期:2010-03-01 00:00:00

  • Left ventricular mass correlates with fat-free mass but not fat mass in adults.

    abstract:BACKGROUND:Left ventricular mass is associated with body size, obesity and blood pressure. Echocardiography is routinely used to estimate this parameter, which is usually indexed to body surface area to allow comparisons to be made between individuals and groups of different body size. However, in obese subjects, using...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199917040-00016

    authors: Whalley GA,Gamble GD,Doughty RN,Culpan A,Plank L,MacMahon S,Sharpe N

    更新日期:1999-04-01 00:00:00

  • Diurnal blood pressure loads are associated with lower cognitive performances in controlled-hypertensive elderly individuals.

    abstract:INTRODUCTION:Hypertension in midlife adults is associated with cognitive decline later in life. In individuals treated for hypertension, blood pressure (BP) loads have been associated with end organ damages. This study examines whether BP load inversely correlates with performance in cognitive tasks in normotensive or ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000002155

    authors: Noriega de la Colina A,Wu R,Desjardins-Crépeau L,Badji A,Lamarre-Cliche M,Doyon J,Bherer L,Girouard H

    更新日期:2019-11-01 00:00:00

  • Predictors of mortality in patients with type 2 diabetes with or without diabetic nephropathy: a follow-up study.

    abstract:OBJECTIVE:To evaluate the prognostic significance of cardiovascular risk factors including 24-h ambulatory blood pressure level and rhythm for all-cause mortality in type 2 diabetic patients. METHODS:In a prospective observational study, 104 patients with type 2 diabetes were followed: 51 patients with diabetic nephro...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e3282f06428

    authors: Astrup AS,Nielsen FS,Rossing P,Ali S,Kastrup J,Smidt UM,Parving HH

    更新日期:2007-12-01 00:00:00

  • New-onset hypertension and risk for chronic kidney disease in the Japanese general population.

    abstract:OBJECTIVES:Our aims were to assess the progression rate of normotension and prehypertension to hypertension in Japan, and the effect of the new-onset hypertension on chronic kidney disease (CKD). METHODS:This was a nationwide study of 45 378 Japanese aged 40-74 years (mean age 60 years, 37% men) without hypertension o...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000000344

    authors: Yano Y,Fujimoto S,Sato Y,Konta T,Iseki K,Iseki C,Moriyama T,Yamagata K,Tsuruya K,Narita I,Kondo M,Kimura K,Asahi K,Kurahashi I,Ohashi Y,Watanabe T

    更新日期:2014-12-01 00:00:00

  • Haemorrhage increases the pressor effect of angiotensin-(1-7) but not of angiotensin II at the rat rostral ventrolateral medulla.

    abstract:OBJECTIVE:To evaluate the effects of angiotensins acting at the rostral ventrolateral medulla (RVLM) on the cardiovascular adjustments following haemorrhage. DESIGN:Changes in mean arterial pressure (MAP) and heart rate (HR) produced by micro-injections of angiotensin II (Ang II) and angiotensin (Ang)-(1-7) and differ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199917080-00014

    authors: Lima DX,Campagnole-Santos MJ,Fontes MA,Khosla MC,Santos RA

    更新日期:1999-08-01 00:00:00

  • Differences in aortic response to vasoactive stimuli in Japanese and Lyon rats. The role of hypertension.

    abstract:OBJECTIVE:We have previously shown that conduit arteries of normotensive (WKY) and hypertensive (SHR) Japanese rats differ from normotensive (LN) and hypertensive (LH) Lyon rats in terms of lower aortic thickness and higher collagen III content, whereas differences in vasoactive properties are unknown. METHODS:Aortic ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199917100-00007

    authors: Chamiot-Clerc P,Legrand M,Sassard J,Safar ME,Renaud JF

    更新日期:1999-10-01 00:00:00

  • Heritability of plasma leptin levels: a twin study.

    abstract:OBJECTIVE:To examine the influence of genetic factors on plasma leptin levels. SUBJECTS AND METHODS:We measured plasma leptin levels, body mass index and body fat distribution in healthy young female monozygotic (n = 19) and dizygotic (n = 14) twins. The twin zygosity was verified by determination of short tandem repe...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199917010-00005

    authors: Narkiewicz K,Szczech R,Winnicki M,Chrostowska M,Pawlowski R,Lysiak-Szydlowska W,Choe I,Kato M,Sivitz WI,Krupa-Wojciechowska B,Somers VK

    更新日期:1999-01-01 00:00:00