Growth in utero and blood pressure levels in the next generation.

abstract：OBJECTIVE:To assess the diagnostic accuracy of recommendations for self-monitoring blood pressure (BP) for diagnosing hypertension in primary care. METHODS:Two hundred and forty-seven consecutive participants with raised (≥130 mmHg systolic) BP measured by their general practitioner from four primary care practices in...

journal_title：Journal of hypertension

authors： Nunan D,Thompson M,Heneghan CJ,Perera R,McManus RJ,Ward A

更新日期：2015-04-01 00:00:00

abstract：:To determine the role of the parasympathetic system in the development of essential hypertension, the concentrations of acetylcholine (ACh) as a parasympathetic marker and norepinephrine (NE) as a sympathetic marker were measured simultaneously in the heart of spontaneously hypertensive rats (SHR) at 4, 10 and 27 week...

journal_title：Journal of hypertension

authors： Tsuboi H,Ohno O,Ogawa K,Ito T,Hashimoto H,Okumura K,Satake T

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVES:Calcium blockade has been reported to inhibit the contraction of the vascular smooth muscle and the liberation of vasoactive substances by endothelial cells. We tested the effects of calcium blockade on the mechanical properties of the carotid artery in normotensive Wistar-Kyoto (WKY) rats and spontaneously ...

journal_title：Journal of hypertension

authors： Lévy BI,el Fertak L,Pieddeloup C,Barouki F,Safar ME

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To determine whether obese hypertensive patients manifest a diminished regional vasodilator response to an oral glucose challenge. METHODS:Nineteen obese hypertensives (body mass index 34.1 +/- 1.3 kg/m2, blood pressure 144 +/- 3/96 +/- 2 mmHg) and 13 lean controls (23.6 +/- 0.3 kg/m2, 127 +/- 4/83 +/- 3 mmH...

journal_title：Journal of hypertension

authors： Egan BM,Stepniakowski K

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:The prognostic role of endothelial dysfunction, as evaluated by flow-mediated vasodilatation of the brachial artery, has been demonstrated in patients at very high risk. We aimed to investigate whether flow-mediated vasodilatation predicts cardiovascular events in uncomplicated hypertensive patients. METHOD...

journal_title：Journal of hypertension

authors： Muiesan ML,Salvetti M,Paini A,Monteduro C,Galbassini G,Poisa P,Porteri E,Agabiti-Rosei C,Paderno V,Belotti E,Rizzoni D,Castellano M,Agabiti-Rosei E

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Blood pressure (BP)-lowering trials studying efficacy mostly assesses binary outcome events, for example stroke/no stroke. Analysis of ordered categorical vascular events (e.g. three levels: fatal stroke/nonfatal stroke/no stroke) provides information on severity and is more powerful statistically than analy...

journal_title：Journal of hypertension

authors： Geeganage CM,Tracy M,Bath MW,Bath PM

更新日期：2010-10-01 00:00:00

abstract：:The binding of 125I-angiotensin II to human blood cells was investigated. Blood was drawn from healthy volunteers and platelets prepared with minimal contamination of red cells and white blood cells (less than 0.1%). Using thin layer chromatography, degradation of 125I-angiotensin II by platelets could be demonstrated...

journal_title：Journal of hypertension

authors： Mann JF,Sis J,Ritz E

更新日期：1985-04-01 00:00:00

abstract：OBJECTIVES:We examined whether the Rho/Rho-kinase pathway is involved in the pathogenesis of nephrosclerosis in severely hypertensive rats and assessed the effects of long-term treatment with a Rho-kinase inhibitor, fasudil, on kidney function, histological findings, gene expressions, and survival. We also attempted to...

journal_title：Journal of hypertension

authors： Nishikimi T,Koshikawa S,Ishikawa Y,Akimoto K,Inaba C,Ishimura K,Ono H,Matsuoka H

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVES:Reflection of the finger pulse wave form is a valid measure of arterial stiffness, which may be continuously assessed during sleep. We investigated the relationships between sleep, sleep-disordered breathing, hypertension, and pulse propagation time (PPT) in patients with suspected sleep apnea. METHODS:The ...

journal_title：Journal of hypertension

authors： Svedmyr S,Zou D,Sommermeyer D,Ficker JH,Randerath W,Fietze I,Sanner B,Hedner J,Grote L

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To explore the repercussion of cardiac denervation on the short-term blood pressure variability in humans, in order to assess the extent to which the variability of blood pressure is linked to the variability of heart rate. METHODS:Beat-to-beat blood pressure and RR interval time were recorded in 16 heart-tr...

journal_title：Journal of hypertension

authors： van de Borne P,Schintgen M,Niset G,Schoenfeld P,Nguyen H,Degré S,Degaute JP

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:The value of SBP during exercise and recovery period as a risk marker for sudden cardiac death (SCD) is not known. Thus, we assessed the association of SBP during recovery from exercise testing with the risk of SCD. METHODS:SBP was measured every 2 min during and at 2 min after a progressive cycle ergometer ...

journal_title：Journal of hypertension

authors： Laukkanen JA,Willeit P,Kurl S,Mäkikallio TH,Savonen K,Ronkainen K,Rauramaa R

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Orthostatic hypotension, postprandial hypotension, and carotid sinus hypersensitivity are hypotensive syndromes with high prevalence in older people. However, their pathophysiology and prognostic significance remain largely unknown. METHODS:In a retrospective cohort study of 313 consecutive patients visitin...

journal_title：Journal of hypertension

authors： Lagro J,Laurenssen NC,Schalk BW,Schoon Y,Claassen JA,Olde Rikkert MG

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Arterial stiffness measures such as pulse wave velocity (PWV) have a known dependence on actual blood pressure, requiring consideration in cardiovascular risk assessment and management. Given the impact of ageing on arterial wall structure, the pressure-dependence of PWV may vary with age. METHODS:Using a n...

journal_title：Journal of hypertension

authors： Spronck B,Heusinkveld MH,Vanmolkot FH,Roodt JO,Hermeling E,Delhaas T,Kroon AA,Reesink KD

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:The objective of the study was to investigate interarm differences of blood pressure (BP) and its determinants, and to clarify whether both arms are equally good in assessing BP and target organ damage in the general population. METHODS:We studied a representative sample of Finnish adult population with 484 ...

journal_title：Journal of hypertension

authors： Johansson JK,Puukka PJ,Jula AM

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:To investigate the role of angiotensin II in the pathogenesis of hyperinsulinemia-induced hypertension in rats. MATERIALS AND METHODS:Chronic hyperinsulinemia was achieved by infusing insulin (3 mU/kg per min) subcutaneously by an osmotic minipump for 6 weeks. An angiotensin converting enzyme inhibitor (fosi...

journal_title：Journal of hypertension

authors： Fang TC,Huang WC

更新日期：1998-12-01 00:00:00

abstract：:The activity of renal Na-K-ATPase was compared in hypertension-prone (SBH) and hypertension-resistant (SBN) Sabra rats on regular sodium intake and 2-3 weeks after a high sodium diet. ATPase activity was determined in single nephron segments by a micromethod. The activity profile was found to be similar in the two sub...

journal_title：Journal of hypertension

authors： Doucet A,Mekler J,el Mernissi G,Ben-Ishay D

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVE:To compare the prediction of mortality by ambulatory blood pressure monitoring and screening blood pressure measurements in a general population. DESIGN:A prospective cohort study. PATIENTS AND METHODS:We obtained blood pressure data for 1542 subjects (565 men and 977 women) aged > or = 40 years who were fo...

journal_title：Journal of hypertension

authors： Ohkubo T,Imai Y,Tsuji I,Nagai K,Watanabe N,Minami N,Itoh O,Bando T,Sakuma M,Fukao A,Satoh H,Hisamichi S,Abe K

更新日期：1997-04-01 00:00:00

abstract：:The effect on blood pressure (BP) of acute and chronic suppression of angiotensin (ANG) II was studied in the two-kidney, one clip hypertensive rat. Conscious, chronically catheterized rats were given a bolus injection of captopril (2.5 mg/kg) followed by a chronic infusion of either dextrose or captopril (1 mg/kg per...

journal_title：Journal of hypertension

authors： Wallace EC,Balmforth AJ,Morton JJ

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:We studied the vasoconstrictor effects of the thromboxane A2 (TxA2) analogue U46619 in the perfused hind limb of rats under constant flow before and after intravenous injection of irbesartan, an angiotensin II AT1 receptor antagonist, to test whether irbesartan interacts in vivo with the thromboxane A2/prosta...

journal_title：Journal of hypertension

authors： Fukuhara M,Neves LA,Li P,Diz DI,Ferrario CM,Brosnihan KB

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:Hypertension affects cerebrovascular autoregulation and increases the risk of cerebrovascular events and dementia. Notably, it is associated with cerebrovascular remodeling and lower resting cerebral blood flow (CBF). We wanted to determine, using arterial spin-labeling-MRI, the impact of a head-down tilt (HD...

journal_title：Journal of hypertension

authors： Seiller I,Pavilla A,Ognard J,Ozier-Lafontaine N,Colombani S,Cepeda Ibarra Y,Mejdoubi M

更新日期：2020-12-09 00:00:00

abstract：OBJECTIVES:Sodium is the mineral that has been, mainly, linked to hypertension and cardiovascular disease. It is found naturally in many foods, but is also used in the food industry and manufacturing. Identification of total sodium intake, as well as 'hidden' sodium intake from food sources early in life is necessary. ...

journal_title：Journal of hypertension

authors： Magriplis E,Farajian P,Pounis GD,Risvas G,Panagiotakos DB,Zampelas A

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Cardiac angiotensin AT1 receptors have been found in several animal species. In-vitro studies performed on cardiac preparations have shown that angiotensin II (ANG II) exerts a positive inotropic effect; however, in-vivo results have allowed no definitive conclusion to be drawn. The reasons behind these cont...

journal_title：Journal of hypertension

authors： Marano G,Formigari R,Vergari A

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVES:High blood pressure is known to be associated with higher cardiovascular risk. The emphasis has shifted over time from diastolic pressure to systolic pressure and variability in blood pressure. This study examined the impact of transient and sustained diastolic hypertension on later mortality. METHODS:In th...

journal_title：Journal of hypertension

authors： Peters R,Wells F,Bulpitt C,Beckett N

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Hypertension and fractures related to osteoporosis are major public health problems that often coexist. This study examined the associations between exposure to different antihypertensive drug classes and the risk of hip fracture in hypertensive patients. METHOD:We included 59 246 individuals, 50 years and o...

journal_title：Journal of hypertension

authors： Bokrantz T,Schiöler L,Boström KB,Kahan T,Mellström D,Ljungman C,Hjerpe P,Hasselström J,Manhem K

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Aortic (central) blood pressure (BP) differs from brachial BP and may be a superior predictor of cardiovascular events. However, its measurement is currently restricted to research settings, owing to a moderate level of operator dependency. We tested a new noninvasive device in a large UK cohort. The device ...

journal_title：Journal of hypertension

authors： Park CM,Korolkova O,Davies JE,Parker KH,Siggers JH,March K,Tillin T,Chaturvedi N,Hughes AD

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:Lower parental education is associated with higher adolescent blood pressure (BP). We examined the contribution of modifiable risk factors from infancy to adolescence that could potentially explain the link between parental education and SBP and DBP in the offspring. METHODS:In a prospective Chinese birth c...

journal_title：Journal of hypertension

authors： Kwok MK,Schooling CM,Subramanian SV,Leung GM,Kawachi I

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To assess the antihypertensive efficacy and safety of the novel AT1 receptor antagonist, telmisartan, compared with that of enalapril in elderly patients with mild to moderate hypertension. DESIGN:A 26-week, multicenter, double-blind, parallel-group, dosage titration study. METHODS:A total of 278 patients a...

journal_title：Journal of hypertension

authors： Karlberg BE,Lins LE,Hermansson K

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:Hypertension is a major risk factor for cardiovascular disease. Polymorphism in the beta2-adrenergic receptor (ADRB2) and nitric oxide synthase 3 (NOS3) genes is associated with clinical cardiovascular phenotypes. The Arg16Gly and Glu298Asp polymorphisms of ADRB2 and NOS3 genes, respectively, have been report...

journal_title：Journal of hypertension

authors： Misono M,Maeda S,Iemitsu M,Nakata Y,Otsuki T,Sugawara J,Zempo H,Yoshizawa M,Miyaki A,Kuno S,Matsuda M,Ajisaka R

更新日期：2009-07-01 00:00:00

abstract：:Fish and fish oils have been reported to reduce blood pressure in normotensives and untreated hypertensives. The present study examined the effect of dietary supplementation with fish oil on blood pressure in 20 treated hypertensives with controlled blood pressures who continued their usual antihypertensive drug treat...

journal_title：Journal of hypertension

authors： Wing LM,Nestel PJ,Chalmers JP,Rouse I,West MJ,Bune AJ,Tonkin AL,Russell AE

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Telmisartan is a unique AT1 receptor blocker with a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonistic action. Activation of PPAR-gamma could prevent inflammation and brain damage. METHOD:We investigated the beneficial effect of telmisartan on ischemic brain damage via PPAR-gamma activa...

journal_title：Journal of hypertension

authors： Iwanami J,Mogi M,Tsukuda K,Min LJ,Sakata A,Jing F,Iwai M,Horiuchi M

更新日期：2010-08-01 00:00:00