The angiotensin II AT1 receptor antagonist irbesartan prevents thromboxane A2-induced vasoconstriction in the rat hind-limb vascular bed in vivo.

abstract：OBJECTIVE:Blood pressure normally declines during the night ('dipping'); a blunted nocturnal decline is an important cardiovascular risk factor. Marriage may be associated with lower ambulatory blood pressure, although this may be confounded by socio-economic and dietary factors. We examined the association of marital ...

journal_title：Journal of hypertension

authors： Causland FR,Sacks FM,Forman JP

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Hypertension control is often inadequate in HIV patients. In a contemporary, nationwide cohort of Italian HIV-infected adults, we assessed time trends in hypertension prevalence, awareness, treatment, and control. We also evaluated predictors of cardiovascular events and of new-onset hypertension. METHODS:M...

journal_title：Journal of hypertension

authors： De Socio GV,Ricci E,Maggi P,Parruti G,Celesia BM,Orofino G,Madeddu G,Martinelli C,Menzaghi B,Taramasso L,Bonfanti P,Pucci G,Schillaci G,CISAI study group.

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:To determine the effects of angiotensin II (AII) (1-8) on cytosolic free calcium concentrations in the absence and in the presence of the selective angiotensin subtype 1 (AT1) receptor antagonist losartan and of the selective angiotensin subtype 2-receptor antagonist P-186 in human peripheral blood mononuclea...

journal_title：Journal of hypertension

authors： Lijnen P,Fagard R,Petrov V

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVE:Neuropeptide W (NPW), an endogenous ligand for the G protein-coupled receptor 7 (GPR7), was first found to make important roles in central nerve system. In periphery, NPW was also present and regulated intracellular calcium homeostasis by L-type calcium channels. This study was designed to discover the effect...

journal_title：Journal of hypertension

authors： Ji L,Zhu H,Chen H,Fan W,Chen J,Chen J,Zhu G,Wang J

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVES:Evidence about sex differences in blood pressure (BP) at the time of acute stroke presentation is scarce. We aimed to summarize available data on sex differences in BP at the time of acute stroke presentation, including stratification by prior history of hypertension and stroke subtype. METHODS:We performed...

journal_title：Journal of hypertension

authors： Li J,Yang SC,Moullaali TJ,Chen R,Woodward M,Carcel C,Delcourt C,Sandset EC,Anderson C,Chen G,Wang X

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Increased arterial stiffness is associated with cardiovascular morbidity and mortality among hypertensive patients. OBJECTIVES:To assess the relationship between ambulatory arterial stiffness index (AASI) and subclinical left ventricular (LV) systolic dysfunction assessed by 2-D speckle-tracking echocardiog...

journal_title：Journal of hypertension

authors： Ahmed TAN,Shams-Eddin H,Fathy MA,El-Naggar HM,Kishk YT

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The catalytic alpha and smaller beta subunits of the plasma membrane Na,K-ATPase occur in various molecular forms (alpha1, alpha2, alpha3, beta1 and beta2). The alpha isoforms of the enzyme have varying affinities for ouabain and exist in different tissues with particular distribution patterns. OBJECTIVE:To...

journal_title：Journal of hypertension

authors： Mayol V,Dignat-George F,Gerbi A,Martin-Vasallo P,Lesaule G,Sampol J,Maixent JM

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVE:To compare the effects of the angiotensin II receptor antagonist candesartan with the angiotensin-converting enzyme inhibitor enalapril on myocardial fibrosis evaluated by echoreflectivity analysis. METHODS:Hypertensive patients (n = 196) with echocardigraphically documented left ventricular hypertrophy were...

journal_title：Journal of hypertension

authors： Ciulla MM,Paliotti R,Esposito A,Cuspidi C,Muiesan ML,Rosei EA,Magrini F,Zanchetti A

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVES:The goal of this study was to compare the cardiovascular responses to behavioural stressors of three groups of adolescents who differed in blood pressure status across assessments. DESIGN:Casual blood pressure of adolescents who were identified as having elevated blood pressure during a school screen was re...

journal_title：Journal of hypertension

authors： Saab PG,Llabre MM,Ma M,DiLillo V,McCalla JR,Fernander-Scott A,Copen R,Gellman M,Schneiderman N

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To identify predictors of pregnancy-induced hypertension and pre-eclampsia in 212 nulliparous women before 20 weeks' gestation and at approximately 28 weeks' gestation. STUDY DESIGN:A randomized, prospective study in a teaching hospital. We performed standardized measurements of systolic and diastolic arteri...

journal_title：Journal of hypertension

authors： Broughton Pipkin F,Sharif J,Lal S

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:In this study, we tested the hypothesis that long-term Rho-kinase inhibition would reverse nitro-L-arginine methyl ester-exacerbated nephrosclerosis in spontaneously hypertensive rats and attempted to elucidate the mechanism involved. METHODS:Five groups (each n = 8) were studied: untreated spontaneously hy...

journal_title：Journal of hypertension

authors： Koshikawa S,Nishikimi T,Inaba C,Akimoto K,Matsuoka H

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Cardiac angiotensin AT1 receptors have been found in several animal species. In-vitro studies performed on cardiac preparations have shown that angiotensin II (ANG II) exerts a positive inotropic effect; however, in-vivo results have allowed no definitive conclusion to be drawn. The reasons behind these cont...

journal_title：Journal of hypertension

authors： Marano G,Formigari R,Vergari A

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:In familial hyperaldosteronism type I (FH-I), glucocorticoid treatment suppresses adrenocorticotrophic hormone-regulated hybrid gene expression and corrects hyperaldosteronism. OBJECTIVE:To determine whether the wild-type aldosterone synthase genes, thereby released from chronic suppression, are capable of ...

journal_title：Journal of hypertension

authors： Stowasser M,Taylor WL,Gartside MG,Tunny TJ,Gordon RD

更新日期：1997-12-01 00:00:00

abstract：:Two formulations of felodipine, conventional and extended release (ER) tablets, were compared in a double-blind, crossover study of patients whose blood pressure was not being controlled using metoprolol 100 mg once daily. Nineteen patients with a supine diastolic blood pressure greater than or equal to 95 mmHg after ...

journal_title：Journal of hypertension

authors： McGrath BP,Langton D,Matthews PG,Syme S,Treloar K,McNeil JJ

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVE:The primary aim of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS) is to determine the effects of a long-term angiotensin converting enzyme (ACE)-inhibitor-based blood-pressure-lowering regimen on the risk of stroke among patients with a history of stroke or transient ischaemic attack (TI...

journal_title：Journal of hypertension

authors：

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:To investigate the factors affecting survival in patients with malignant hypertension by analysing the prognosis of all of the patients referred to the City Hospital, Birmingham, with malignant hypertension since 1965. RESULTS:We identified 315 patients with malignant hypertension (211 men, 104 women; mean a...

journal_title：Journal of hypertension

authors： Lip GY,Beevers M,Beevers DG

更新日期：1995-08-01 00:00:00

abstract：:Hypertension is associated with thickening of the wall of resistance vessels, but the cellular or genetic basis of this is unclear. Cell proliferation and intracellular alkalinization via increased Na+/H+ exchange are linked in the response of tissues to growth factors. To define a possible cellular basis for vascular...

journal_title：Journal of hypertension

authors： Ng LL,Dudley C,Bomford J,Hawley D

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVE:To examine the relationship between blood pressure and depression in a large sample of noninstitutionalized elderly people. METHODS:Cross-sectional community-based study in 9294 participants aged 65 years and over, living at home, in three French cities (Bordeaux, Dijon and Montpellier). Participants were ca...

journal_title：Journal of hypertension

authors： Lenoir H,Lacombe JM,Dufouil C,Ducimetière P,Hanon O,Ritchie K,Dartigues JF,Alpérovitch A,Tzourio C

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Cathepsin L (CTSL1) catalyzes the formation of peptides that influence blood pressure (BP). Naturally occurring genetic variation or targeted ablation of the Ctsl1 locus in mice yield cardiovascular pathology. Here, we searched for genetic variation across the human CTSL1 locus and probed its functional effe...

journal_title：Journal of hypertension

authors： Mbewe-Campbell N,Wei Z,Zhang K,Friese RS,Mahata M,Schork AJ,Rao F,Chiron S,Biswas N,Kim HS,Mahata SK,Waalen J,Nievergelt CM,Hook VY,O'Connor DT

更新日期：2012-10-01 00:00:00

abstract：:Interstrain restriction fragment length polymorphism was detected after Southern blot hybridization of spontaneously hypertensive (SHR) and control (WKY) rat DNA digested by Bam HI restrictase with a v-fos probe. The SHR genome was characterized by an additional minor band of 4.0 kb. Other restriction fragment length ...

journal_title：Journal of hypertension

authors： Kotelevtsev YV,Brashishkite DA,Spitkovski DD,Kiselev FL,Postnov YV

更新日期：1988-10-01 00:00:00

abstract：OBJECTIVE:To examine the interaction of sodium intake with genetic variations of the angiotensinogen gene and hypertension. DESIGN:A community-based case-reference study. SETTING:Two rural Japanese communities. PARTICIPANTS:Non-overweight and non-drinking Japanese men and women: 229 hypertensives and 229 age-, sex- ...

journal_title：Journal of hypertension

authors： Iso H,Harada S,Shimamoto T,Sato S,Kitamura A,Sankai T,Tanigawa T,Iida M,Komachi Y

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:The aim of this cross-sectional study was to investigate the association between consumption of sugar-sweetened and diet soft drinks with blood pressure (BP) in adolescents. METHODS:Fifth graders of 20 public schools were invited to participate in an intervention aimed at behavioral dietary changes and had t...

journal_title：Journal of hypertension

authors： Souza Bda S,Cunha DB,Pereira RA,Sichieri R

更新日期：2016-02-01 00:00:00

abstract：:An Na+,K+-ATPase inhibitor possessing inhibitory activity against the specific binding of ouabain to Na+,K+-ATPase has been purified from the plasma of acutely saline-infused hogs. The purification was performed by a combination of Amberlite XAD-2 adsorption chromatography and five steps of high-pressure liquid chroma...

journal_title：Journal of hypertension

authors： Tamura M,Inagami T,Kinoshita T,Kuwano H

更新日期：1987-04-01 00:00:00

abstract：OBJECTIVES:To discuss changes during the past decades in the prevalence and in the patterns of detection, treatment and control of arterial hypertension in the general Belgian population aged 25-64 years. DESIGN:Data from two cross-sectional cardiovascular disease risk factor surveys of the general population aged 25-...

journal_title：Journal of hypertension

authors： De Henauw S,De Bacquer D,Fonteyne W,Stam M,Kornitzer M,De Backer G

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:Studies have shown that famine exposure during early life may increase the risk of cardiovascular disease (CVD), hypertension, and diabetes during adulthood. We aimed to assess whether exposure to the Chinese famine (1959-1961) modifies the association between hypertension and CVD. METHODS:We investigated da...

journal_title：Journal of hypertension

authors： Shi Z,Nicholls SJ,Taylor AW,Magliano DJ,Appleton S,Zimmet P

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:The present study was designed to examine whether or not excessive Zn intake affects systemic blood pressure (BP) levels in a normotensive state. METHODS:Systolic BP (SBP) and mean arterial pressure (MAP) before and after administration of the nitric oxide synthase (NOS) inhibitor, N-nitro-L-arginine methyl...

journal_title：Journal of hypertension

authors： Yanagisawa H,Sato M,Nodera M,Wada O

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:The objective of this study was to estimate the prevalence and distribution of hypertension and to determine the status of hypertension awareness, treatment and control in the Portuguese adult population. METHODS:This study was conducted in 2003, and a multistage cluster sampling method was used to select a...

journal_title：Journal of hypertension

authors： Macedo ME,Lima MJ,Silva AO,Alcantara P,Ramalhinho V,Carmona J

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:Normotensive rats fed a high fructose diet (HFD) develop hypertriglyceridemia, hyperinsulinemia and hypertension. The glomerular changes observed in the kidneys of these animals are similar to those observed in diabetic rats. The aim of this study was to evaluate whether lacidipine could be effective not only...

journal_title：Journal of hypertension

authors： Cosenzi A,Bernobich E,Plazzotta N,Seculin P,Odoni G,Bellini G

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Widely evaluated regarding the genetic make-up of essential hypertension are the renin-angiotensin-aldosterone system (RAAS) genes polymorphisms, whereas results are often not reproducible. METHOD:We thus focused on a large Fangshan population to explore association of thirteen polymorphisms in five genes o...

journal_title：Journal of hypertension

authors： Niu W,Qi Y,Hou S,Zhai X,Zhou W,Qiu C

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:To investigate whether nondipping and diabetes are independently related to metabolic risk profile and prevalence of target organ damage in a population setting. METHODS:A population-based cohort of 70-year-old men (n = 1057) was examined with 24-h ambulatory blood pressure monitoring, euglycemic hyperinsuli...

journal_title：Journal of hypertension

authors： Björklund K,Lind L,Andrén B,Lithell H

更新日期：2002-08-01 00:00:00