Leucocyte intracellular pH and Na+/H+ antiport activity in human hypertension.

abstract：OBJECTIVE:In essential hypertension, the mechanical properties of the radial artery have been shown to be largely unaltered, whereas more controversial and less reliable data have been obtained for the common carotid artery. We therefore examined the distensibility/pressure relationships of the predominantly elastic co...

journal_title：Journal of hypertension

authors： Stella ML,Mircoli L,Mangoni AA,Giannattasio C,Ferrari AU,Mancia G

更新日期：1997-12-01 00:00:00

abstract：:Uptake of 45Ca was measured in rings of thoracic aorta from rabbits with hypertension, induced by cellophane perinephritis (Page hypertension: one-kidney, one wrap). Basal 45Ca uptake was increased significantly in the hypertensive group (sham: 100 +/- 3, hypertensive: 133 +/- 11 nmol/g wet weight, n = 6). 45Ca uptake...

journal_title：Journal of hypertension

authors： Dong Y,Wadsworth RM

更新日期：1987-12-01 00:00:00

abstract：:Former guidelines on hypertension never made a commitment to the detection of microalbuminuria for screening or follow-up of hypertensive patients. On the other hand, growing evidence support the contributory role of microalbuminuria in the prediction of absolute cardiovascular risk in hypertension and document the po...

journal_title：Journal of hypertension

authors： Volpe M,Cosentino F,Ruilope LM

更新日期：2003-07-01 00:00:00

abstract：:Cardiovascular risk increases with chronological as well as biological aging, and one marker of this might be telomere length. The telomere cap is located at the end of the DNA helix and serves to protect its end. This is an evolutionary adaptation which has resulted in stabilization of the DNA strand within the chrom...

journal_title：Journal of hypertension

authors： Nilsson PM

更新日期：2012-06-01 00:00:00

abstract：:Diabetic nephropathy has developed into a worldwide epidemic and is responsible for the majority of end-stage renal disease in most countries. Antihypertensive treatment slows the progression of the disease. In addition, blockade of the renin-angiotensin system reduces the degree of albuminuria and angiotensin II rece...

journal_title：Journal of hypertension

authors： Haller H,Viberti GC,Mimran A,Remuzzi G,Rabelink AJ,Ritz E,Rump LC,Ruilope LM,Katayama S,Ito S,Izzo JL Jr,Januszewicz A

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Epidemiological investigations have demonstrated a close association between heavy alcohol consumption and hypertension. The mechanisms of this association, however, remain elusive. We studied the effects of alcohol withdrawal on blood pressure, hormonal parameters, and circulating markers of endothelial act...

journal_title：Journal of hypertension

authors： Soardo G,Donnini D,Varutti R,Milocco C,Basan L,Esposito W,Casaccio D,Isola M,Soldano F,Sechi LA

更新日期：2006-08-01 00:00:00

abstract：:An Na+,K+-ATPase inhibitor possessing inhibitory activity against the specific binding of ouabain to Na+,K+-ATPase has been purified from the plasma of acutely saline-infused hogs. The purification was performed by a combination of Amberlite XAD-2 adsorption chromatography and five steps of high-pressure liquid chroma...

journal_title：Journal of hypertension

authors： Tamura M,Inagami T,Kinoshita T,Kuwano H

更新日期：1987-04-01 00:00:00

abstract：OBJECTIVE:Prior to the discovery of chloride channel Kb with a variant threonine change to serine at position 481 (CLCNKB-T481S) there were no variants or clinical disorders associated with gain-of-function defects in thick ascending limb of the kidney channels or transporters. CLCNKB-T481S is a novel gain-of-function ...

journal_title：Journal of hypertension

authors： Sile S,Velez DR,Gillani NB,Narsia T,Moore JH,George AL Jr,Vanoye CG,Williams SM

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Recent evidence suggests that central aortic blood pressure may be a better predictor of cardiovascular risk than peripheral blood pressure. The central SBP (cSBP) can be estimated from the late systolic shoulder of the radial pulse waveform. We compared the second systolic peak of the radial waveform (pSBP(...

journal_title：Journal of hypertension

authors： Hickson SS,Butlin M,Mir FA,Graggaber J,Cheriyan J,Khan F,Grace AA,Yasmin,Cockcroft JR,Wilkinson IB,McEniery CM,Anglo-Cardiff Collaboration Trial Investigators.

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:Age, hypertension, diabetes mellitus and a history of cardiovascular disease are the most important factors related to the presence of cerebral white matter lesions (WML), which are a common finding in elderly people. This study investigates which factors related to hypertension per se are associated with the...

journal_title：Journal of hypertension

authors： Sierra C,de La Sierra A,Mercader J,Gómez-Angelats E,Urbano-Márquez A,Coca A

更新日期：2002-03-01 00:00:00

abstract：:The treatment of essential hypertension continues to be carried out by drugs, combined with the adaptation of life style. The development of various types of antihypertensive drugs has not only greatly improved the management of hypertension, but also offered significant methodological sophistication of the pharmacolo...

journal_title：Journal of hypertension

authors： van Zwieten PA

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:The major advantage of dual inhibitors of neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE) is their ability to lower blood pressure irrespective of renin or volume status. The aim of this study was to determine whether dual NEP/ACE inhibition produces different effects on cardiovascular str...

journal_title：Journal of hypertension

authors： Farina NK,Johnston CI,Burrell LM

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:Optimal medication use obscures the impact of physical activity on traditional cardiometabolic risk factors. We evaluated the relationship between step counts and carotid-femoral pulse wave velocity (cfPWV), a summative risk indicator, in patients with type 2 diabetes and/or hypertension. RESEARCH DESIGN AND...

journal_title：Journal of hypertension

authors： Dasgupta K,Rosenberg E,Joseph L,Trudeau L,Garfield N,Chan D,Sherman M,Rabasa-Lhoret R,Daskalopoulou SS

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:Blood pressure (BP) variability (BPV) may offer independent prognostic information. However, data supporting this notion are inconsistent, and this may be due to the wide variety of methodologies used for measuring BPV. A systematic analysis on the effect of BPV methodologies on BPV itself has never been und...

journal_title：Journal of hypertension

authors： Veloudi P,Sharman JE

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Hypertension in midlife has been associated with increased risk of stroke and neurocognitive decline. Few studies, however, have examined neurocognition among individuals with treatment-resistant hypertension or potential mechanisms by which treatment-resistant hypertension may impair neurocognition. METHOD...

journal_title：Journal of hypertension

authors： Smith PJ,Blumenthal JA,Hinderliter AL,Mabe SM,Schwartz JE,Avorgbedor F,Sherwood A

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on pneumonia hospitalization in patients with stroke history in Taiwan. METHODS:We conducted a case-crossover study using the National Health Insurance Research Database in Taiwan during the period from...

journal_title：Journal of hypertension

authors： Liu CL,Shau WY,Wu CS,Lai MS

更新日期：2012-11-01 00:00:00

abstract：INTRODUCTION:QT interval prolongation increases the risk of sudden death in several medical conditions. Patients with primary aldosteronism and salt-sensitive hypertension experience more cardiovascular events than those with normal-renin essential hypertension. QT interval prolongation might represent one of the risk ...

journal_title：Journal of hypertension

authors： Maule S,Mulatero P,Milan A,Leotta G,Caserta M,Bertello C,Rabbia F,Veglio F

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:Functional sex differences are described in several vascular beds. In the case of renal vessels, sex differences could influence processes like regulation of blood pressure and ion balance. Angiotensin II and nitric oxide are important regulators of renal vascular tone. Females have higher nitric oxide syntha...

journal_title：Journal of hypertension

authors： Viegas VU,Liu ZZ,Nikitina T,Perlewitz A,Zavaritskaya O,Schlichting J,Persson PB,Regitz-Zagrosek V,Patzak A,Sendeski MM

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:We investigated the contribution of reduced nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase-dependent reactive oxygen species (ROS) generation to the pathogenesis of diastolic heart failure (DHF) in Dahl salt-sensitive (DS) hypertensive rats, with the aim of testing our hypothesis that the cardiop...

journal_title：Journal of hypertension

authors： Guo P,Nishiyama A,Rahman M,Nagai Y,Noma T,Namba T,Ishizawa M,Murakami K,Miyatake A,Kimura S,Mizushige K,Abe Y,Ohmori K,Kohno M

更新日期：2006-06-01 00:00:00

abstract：:The benefit of blood pressure-lowering therapy in individuals with normal blood pressure who are at high cardiovascular risk creates a challenge in how best to advocate such therapy. Arguments based on a putative causal role for blood pressure and the need to reduce blood pressure may be less likely to succeed than ar...

journal_title：Journal of hypertension

authors： Campbell DJ

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:International recommendations have classified brachial blood pressure (BP) in subgroups enabling better cardiovascular risk stratification. Central BP is an independent predictor of cardiovascular risk, differing from brachial BP through the predominant influence of arterial stiffness and wave reflections. C...

journal_title：Journal of hypertension

authors： Safar ME,Blacher J,Protogerou A,Achimastos A

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:Recently, the nanomechanical properties (i.e. stiffness) of endothelial cells have been identified as crucial for appropriate endothelial function. One major determinant of endothelial stiffness is the endothelial sodium channel (EnNaC). EnNaC-dependent stiffening leads to reduced nitric oxide release, which...

journal_title：Journal of hypertension

authors： Lenders M,Hofschröer V,Schmitz B,Kasprzak B,Rohlmann A,Missler M,Pavenstädt H,Oberleithner H,Brand SM,Kusche-Vihrog K,Brand E

更新日期：2015-12-01 00:00:00

abstract：:To investigate the effects of changes in sodium balance on blood pressure and leucocyte sodium transport, normotensive first-degree relatives of hypertensive patients and control subjects were randomized to receive low- and high-salt diets for 2 weeks, separated by a wash-out period of 2 weeks. High-salt intake failed...

journal_title：Journal of hypertension

authors： Heagerty AM,Alton SM,el-Ashry A,Bing RF,Thurston H,Swales JD

更新日期：1986-06-01 00:00:00

abstract：OBJECTIVE:It has been shown that angiotensin-converting enzyme inhibition or angiotensin receptor blockade may improve endothelial dysfunction, an early manifestation of atherosclerosis, in patients with diabetes. Whether this protective effect is mediated through blood pressure-lowering effects or other specific mecha...

journal_title：Journal of hypertension

authors： Flammer AJ,Hermann F,Wiesli P,Schwegler B,Chenevard R,Hürlimann D,Sudano I,Gay S,Neidhart M,Riesen W,Ruschitzka F,Lüscher TF,Noll G,Lehmann R

更新日期：2007-04-01 00:00:00

abstract：:Adequate evaluation of automated sphygmomanometers, in terms of safety, accuracy, mechanical reliability, patient acceptability and ability to record ambulatory blood pressure is essential before these devices are used in clinical practice and in clinical trials. We have evaluated the accuracy and performance of the A...

journal_title：Journal of hypertension

authors： Jamieson MJ,Fowler G,MacDonald TM,Webster J,Witte K,Lawson L,Crichton W,Jeffers TA,Petrie JC

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVES:To discuss changes during the past decades in the prevalence and in the patterns of detection, treatment and control of arterial hypertension in the general Belgian population aged 25-64 years. DESIGN:Data from two cross-sectional cardiovascular disease risk factor surveys of the general population aged 25-...

journal_title：Journal of hypertension

authors： De Henauw S,De Bacquer D,Fonteyne W,Stam M,Kornitzer M,De Backer G

更新日期：1998-03-01 00:00:00

abstract：:Neutrophils possess a plasma-membrane-bound reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase which catalyzes superoxide (O2-) formation and is activated by a variety of stimuli. Recently, neutrophils of patients with essential hypertension (EHT) have been reported to generate O2- at rates up to four...

journal_title：Journal of hypertension

authors： Seifert R,Hilgenstock G,Fassbender M,Distler A

更新日期：1991-02-01 00:00:00

abstract：OBJECTIVES:Unlike the 2018 European Society of Cardiology/European Society of Hypertension (ESC/ESH) guideline, the 2017 American College of Cardiology/American Heart Association (ACC/AHA) guideline has recommended a shift in hypertension definition from blood pressure (BP) 140/90-130/80 mmHg. Further, they proposed so...

journal_title：Journal of hypertension

authors： Gijón-Conde T,Sánchez-Martínez M,Graciani A,Cruz JJ,López-García E,Ortolá R,Rodríguez-Artalejo F,Banegas JR

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Patients with essential hypertension exhibit several red blood cell (RBC) ion transport abnormalities, insulin resistance (IR) and increased risk of developing type 2 diabetes. The aims of this study were to assess RBC ion transport activities under basal conditions and to test the in vivo effect of acute hyp...

journal_title：Journal of hypertension

authors： Suchánková G,Vlasáková Z,Zicha J,Vokurková M,Dobesová Z,Pelikánová T

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:To estimate the sensitivity and specificity of self-reported hypertension (HTN) as compared with the clinical diagnosis in epidemiological studies. METHODS:We searched MEDLINE, Embase, Scopus, Web of Science, LILACS, Google Scholar, and ProQuest Dissertations & Theses Global: Health & Medicine databases. In ...

journal_title：Journal of hypertension

authors： Gonçalves VSS,Andrade KRC,Carvalho KMB,Silva MT,Pereira MG,Galvao TF

更新日期：2018-05-01 00:00:00