Preventing microalbuminuria in patients with diabetes: rationale and design of the Randomised Olmesartan and Diabetes Microalbuminuria Prevention (ROADMAP) study.

abstract：BACKGROUND:The objective of this study was to estimate the prevalence and distribution of hypertension and to determine the status of hypertension awareness, treatment and control in the Portuguese adult population. METHODS:This study was conducted in 2003, and a multistage cluster sampling method was used to select a...

journal_title：Journal of hypertension

authors： Macedo ME,Lima MJ,Silva AO,Alcantara P,Ramalhinho V,Carmona J

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:In arteries, agonists such as acetylcholine release an endothelium-derived hyperpolarizing factor (EDHF) that is neither nitric oxide nor prostacyclin. OBJECTIVES:To examine the responses to acetylcholine in segments of forearm veins from patients with chronic renal failure who either had never received dia...

journal_title：Journal of hypertension

authors： Martinez-León JB,Segarra G,Medina P,Vila JM,Lluch P,Peiró M,Otero E,Lluch S

更新日期：2003-10-01 00:00:00

abstract：:: Altered blood pressure (BP) is a common phenomenon in acute ischemic stroke (AIS), with high BP being the most frequent scenario. The pathophysiology of BP changes in AIS is complex and only partially understood. The available evidence indicates that extremely high BP during AIS is associated with a poor outcome. Im...

journal_title：Journal of hypertension

authors： Gąsecki D,Coca A,Cunha P,Hering D,Manios E,Lovic D,Zaninelli A,Sierra C,Kwarciany M,Narkiewicz K,Karaszewski B

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:To test whether the Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene is of functional relevance in humans by altering endothelium-dependent vasodilation. BACKGROUND:The Asp298 variant of the eNOS gene product has been associated with arterial hypertension, coronary artery disease ...

journal_title：Journal of hypertension

authors： Schneider MP,Erdmann J,Delles C,Fleck E,Regitz-Zagrosek V,Schmieder RE

更新日期：2000-12-01 00:00:00

abstract：:Hypertensive disease is known to increase the risks in connection with acute changes in blood pressure due to the presence of pronounced structural as well as functional changes in the cardiovascular system. In the present study the metabolic consequences of fixed haemorrhagic hypotension [mean arterial pressure (MAP)...

journal_title：Journal of hypertension

authors： Wennberg E,Hagberg H,Haljamäe H,Johansson BB

更新日期：1983-10-01 00:00:00

abstract：:The effect of xipamide on the intracellular concentration and transmembrane fluxes of Na+ and K+ was studied in 12 normal male subjects, using a double-blind cross-over design. After a run-in period on placebo for 1 week, the subjects were treated with either placebo (n = 6) or xipamide 20 mg once a day (n = 6) for 16...

journal_title：Journal of hypertension

authors： Lijnen P,Hespel P,Fagard R,Staessen J,Goossens W,Lissens W,Amery A

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVE:To investigate the association between long-term exposure to high-level urban traffic noise and blood pressure in preschool children. DESIGN:Normotensive children (n = 1542), aged 3-7 years and attending kindergartens, had their blood pressures and heart rate measured. Mean values of these circulatory variab...

journal_title：Journal of hypertension

authors： Regecová V,Kellerová E

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:The urinary isoflavonoid equol inhibits membrane Na-K-Cl cotransporters at similar concentrations to those at which furosemide inhibits them, but the significance of this action is not known. OBJECTIVE:To investigate the potential salidiuretic and vascular actions of equol in the rat. METHODS:Renal functio...

journal_title：Journal of hypertension

authors： Gimenez I,Lou M,Vargas F,Alvarez-Guerra M,Mayoral JA,Martinez RM,Garay RP,Alda JO

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:Blood pressure management is a key issue among patients with coronary heart disease (CHD). The present study aimed to identify particular patient groups that may need to be specifically targeted in secondary prevention of CHD. METHODS:EUROASPIRE III is a cross-sectional study conducted in 2006-2007 among pa...

journal_title：Journal of hypertension

authors： Prugger C,Keil U,Wellmann J,de Bacquer D,de Backer G,Ambrosio GB,Reiner Z,Gaita D,Wood D,Kotseva K,Heidrich J,EUROASPIRE III Study Group.

更新日期：2011-08-01 00:00:00

abstract：:It is widely believed that salt-dependent hypertension is induced and maintained by expansion of intravascular fluid volume resulting from excessive retention of sodium. The purpose of this brief article is to present a series of arguments in support of the thesis that volume overload per se does not raise the arteria...

journal_title：Journal of hypertension

authors： Gavras I,Gavras H

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:This study presents a reliable index inspired by the total variability concept of real analysis in mathematics, called average real variability (ARV), for the prognostic significance of blood pressure variability (BPV) overcoming the pitfalls of the commonly used standard deviation (SD). BACKGROUND:Recent s...

journal_title：Journal of hypertension

authors： Mena L,Pintos S,Queipo NV,Aizpúrua JA,Maestre G,Sulbarán T

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:We tested the hypothesis that qualitative microalbuminuria (MAU) screening in a practice setting would identify non-diabetic hypertensive patients at high risk of developing cardiovascular disease. DESIGN:We enrolled general practitioners throughout Germany, who obtained histories, physical examinations, and...

journal_title：Journal of hypertension

authors： Agrawal B,Berger A,Wolf K,Luft FC

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:Currently, normative means and ranges of blood pressure (BP) and pulse rates in Japanese newborns are not available. The objective of the present study was to estimate BP, pulse rate, and their distribution among Japanese newborns. METHODS:Using oscillometric devices, arm or calf BP and pulse rate levels wer...

journal_title：Journal of hypertension

authors： Satoh M,Inoue R,Tada H,Hosaka M,Metoki H,Asayama K,Murakami T,Mano N,Ohkubo T,Yagihashi K,Hoshi K,Suzuki M,Imai Y

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:The relation of noninvasive vascular function to sex, sex hormones, and reproductive history in the general population is little understood. METHODS:We simultaneously assessed flow-mediated dilation (FMD) and peripheral arterial tonometry in 454 women (mean age 40.4±16.1 years, age range 19-78 years) and 100...

journal_title：Journal of hypertension

authors： Schnabel RB,Biener MP,Wilde S,Sinning CR,Ojeda FM,Zeller T,Lubos E,Lackner KJ,Warnholtz A,Gori T,Espinola-Klein C,Blankenberg S,Munzel T,Wild PS

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:Neuropeptide W (NPW), an endogenous ligand for the G protein-coupled receptor 7 (GPR7), was first found to make important roles in central nerve system. In periphery, NPW was also present and regulated intracellular calcium homeostasis by L-type calcium channels. This study was designed to discover the effect...

journal_title：Journal of hypertension

authors： Ji L,Zhu H,Chen H,Fan W,Chen J,Chen J,Zhu G,Wang J

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:There is a need for an easily accessible biomarker of sympathetic nervous activation in essential hypertension, but none exists. Heart rate (HR) has been suggested, but requires validation, now doubly important as an elevated HR in hypertension has emerged as an independent cardiovascular risk factor. METHO...

journal_title：Journal of hypertension

authors： Esler M,Lambert G,Esler D,Ika Sari C,Guo L,Jennings G

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:Reversibility of the systemic and renal alterations induced by N(omega)-nitro-L-arginine-methyl ester(L-NAME) was assessed by treatment with irbesartan and enalapril (30 and 10 mg/kg per 24 h, respectively) alone or in combination. DESIGN:L-NAME (20 mg/kg per 24 h) was given to rats for 6 weeks and treatment...

journal_title：Journal of hypertension

authors： Jover B,Herizi A,Casellas D,Mimran A

更新日期：2001-11-01 00:00:00

abstract：:: Phaeochromocytoma and paraganglioma (PPGL) are chromaffin cell tumours that require timely diagnosis because of their potentially serious cardiovascular and sometimes life- threatening sequelae. Tremendous progress in biochemical testing, imaging, genetics and pathophysiological understanding of the tumours has far-...

journal_title：Journal of hypertension

authors： Lenders JWM,Kerstens MN,Amar L,Prejbisz A,Robledo M,Taieb D,Pacak K,Crona J,Zelinka T,Mannelli M,Deutschbein T,Timmers HJLM,Castinetti F,Dralle H,Widimský J,Gimenez-Roqueplo AP,Eisenhofer G

更新日期：2020-08-01 00:00:00

abstract：:The associations of obesity and alcohol consumption with blood pressure and the prevalence of hypertension were studied in 5550 male and female subjects aged 25 to 64 years, surveyed in the National Heart Foundation of Australia 1980 Risk Factor Prevalence Study. Body mass index was significantly and independently ass...

journal_title：Journal of hypertension

authors： MacMahon SW,Blacket RB,Macdonald GJ,Hall W

更新日期：1984-02-01 00:00:00

abstract：OBJECTIVE:Although several studies have reported an association between microalbuminuria and pulse wave velocity in patients with hypertension or diabetes, there have been no reports of their significance in apparently healthy individuals. METHODS:Microalbuminuria and brachial-ankle PWV (baPWV) were investigated in a ...

journal_title：Journal of hypertension

authors： Kim BJ,Lee HA,Kim NH,Kim MW,Kim BS,Kang JH

更新日期：2011-11-01 00:00:00

abstract：AIMS:Selenium is an antioxidant micronutrient with potential associations with hypertension. Few studies have investigated the association of serum selenium concentrations with blood pressure and hypertension in countries with low dietary selenium intake such as Germany, with inconsistent findings. METHODS:We undertoo...

journal_title：Journal of hypertension

authors： Berthold HK,Michalke B,Krone W,Guallar E,Gouni-Berthold I

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:We tested the reproducibility of ambulatory blood pressure (ABP), BP variability, and BP reduction in hypertensive patients. METHODS:Forty-two hypertensive patients were enrolled, and ABP monitoring (ABPM) was performed four times in each patient: twice before and twice after the treatment. Morning BP was de...

journal_title：Journal of hypertension

authors： Eguchi K,Hoshide S,Hoshide Y,Ishikawa S,Shimada K,Kario K

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Daily exposure to air-jet stress (AJS) causes sustained elevations of blood pressure in borderline hypertensive rats (BHR). It is known that the renin-angiotensin system is activated during episodes of behavioral stress, and the purpose of this study was to assess the involvement of renin-angiotensin system i...

journal_title：Journal of hypertension

authors： Coste SC,Qi Y,Brooks VL,McCarron DA,Hatton DC

更新日期：1995-12-01 00:00:00

abstract：:Angioplasty of renal artery stenosis has been used extensively in the last two decades for treating renovascular hypertension, and, more recently, for preserving the jeopardized renal function. A large body of evidence has accumulated indicating that this approach is by far the most convenient for patients with fibrom...

journal_title：Journal of hypertension

authors： Morganti A

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To ascertain the relationships between the kinetic properties of erythrocyte Na+-H+ exchange [maximum kinetic energy (Vmax), Michaelis constant (Km) for internal H+ and Hill's coefficient], Na+-Li+ (Vmax and Km for external Na+), and metabolic parameters in normotensive controls and hypertensive subjects. MA...

journal_title：Journal of hypertension

authors： Semplicini A,Ceolotto G,Felice M,Reato S,Valle R,Gebbin A,Fontebasso A,Serena L,Pessina AC

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:The primary aim of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS) is to determine the effects of a long-term angiotensin converting enzyme (ACE)-inhibitor-based blood-pressure-lowering regimen on the risk of stroke among patients with a history of stroke or transient ischaemic attack (TI...

journal_title：Journal of hypertension

authors：

更新日期：1999-11-01 00:00:00

abstract：:The effects of i.v. injection of intact digoxin antibody (0.3 mg/rat) and of its Fab fragment (40 mg/rat) on blood pressure, cardiac output and total peripheral resistance were measured in conscious spontaneously hypertensive and deoxycorticosterone hypertensive rats. In vitro findings showed that Fab fragment bound r...

journal_title：Journal of hypertension

authors： Mann JF,Miemietz R,Ganten U,Ritz E

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVE:Optimal medication use obscures the impact of physical activity on traditional cardiometabolic risk factors. We evaluated the relationship between step counts and carotid-femoral pulse wave velocity (cfPWV), a summative risk indicator, in patients with type 2 diabetes and/or hypertension. RESEARCH DESIGN AND...

journal_title：Journal of hypertension

authors： Dasgupta K,Rosenberg E,Joseph L,Trudeau L,Garfield N,Chan D,Sherman M,Rabasa-Lhoret R,Daskalopoulou SS

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Homeostasis Model Assessment (HOMA index) is predictive of insulin sensitivity in normal and diabetic patients. This study was designed to see if insulin resistance in hypertensives, measured using the HOMA index, differs, based on salt sensitivity, renin status and sodium intake. METHODS:Fasting insulin and...

journal_title：Journal of hypertension

authors： Raji A,Williams GH,Jeunemaitre X,Hopkins PN,Hunt SC,Hollenberg NK,Seely EW

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:Microalbuminuria (MA) is a marker of adverse outcome in hypertension. The aim of this study was to investigate the association of MA with cardiovascular risk factors and glomerular hyperfiltration in the early stage of hypertension and to assess its predictive value for the development of sustained hypertensi...

journal_title：Journal of hypertension

authors： Palatini P,Mormino P,Mos L,Mazzer A,Dorigatti F,Zanata G,Longo D,Garbelotto R,De Toni R,Graniero G,Pessina AC,HARVEST Study Group.

更新日期：2005-01-01 00:00:00