Abstract:
OBJECTIVE:Studies have shown that famine exposure during early life may increase the risk of cardiovascular disease (CVD), hypertension, and diabetes during adulthood. We aimed to assess whether exposure to the Chinese famine (1959-1961) modifies the association between hypertension and CVD. METHODS:We investigated data of 5772 adults born between 1954 and 1964 from the China Health and Retirement Longitudinal Study. CVD was based on self-reported doctor's diagnosis of heart problems (heart attack, coronary heart disease, angina, congestive heart failure, or other heart problems) and stroke. RESULTS:Overall, hypertension was associated with a doubling of CVD risk (odds ratio 1.97, 1.56-2.48, P < 0.001). There was a significant interaction between hypertension and famine exposure for CVD (P = 0.04). The odds ratio of hypertension for CVD were: 1.69 [95% confidence interval (CI) 1.06-2.72, P = 0.03], 2.35 (95%CI 1.44-3.83, P = 0.001), 2.48 (95%CI 1.49-4.11, P < 0.001), 3.35 (95%CI 1.54-7.27, P = 0.002), and 1.40 (95%CI 0.82-2.38, P = 0.215) among adults in late childhood, mid childhood, early childhood, fetal, and nonexposed cohorts, respectively. The risk gradient between hypertension and CVD across famine cohorts was mainly seen among women, those living in urban areas and those with central obesity. CONCLUSION:Early life exposure to the Chinese famine exacerbated the association between hypertension and CVD, especially among women and those living in urban areas or those with central obesity.
journal_name
J Hypertensjournal_title
Journal of hypertensionauthors
Shi Z,Nicholls SJ,Taylor AW,Magliano DJ,Appleton S,Zimmet Pdoi
10.1097/HJH.0000000000001496subject
Has Abstractpub_date
2018-01-01 00:00:00pages
54-60issue
1eissn
0263-6352issn
1473-5598journal_volume
36pub_type
杂志文章abstract:OBJECTIVE:In hypertensive patients, exaggerated increases in vascular resistance and arterial blood pressure have been reported on changing posture from supine to upright. In this study we tested the hypothesis that in hypertensive subjects, upright posture induces an increase in the vasoconstrictor and pressor respons...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199917010-00015
更新日期:1999-01-01 00:00:00
abstract::A unique tissue kallikrein-binding protein was identified and partially characterized in the brain and serum of Sprague-Dawley rats and in the serum-free conditioned media of mouse anterior pituitary cells (AtT 20) and rodent neuroblastoma x glioma hybrids (NG108-15). Kallikrein and kallikrein-binding protein(s) form ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-198807000-00006
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000001571
更新日期:2018-02-01 00:00:00
abstract::Adequate evaluation of automated sphygmomanometers, in terms of safety, accuracy, mechanical reliability, patient acceptability and ability to record ambulatory blood pressure is essential before these devices are used in clinical practice and in clinical trials. We have evaluated the accuracy and performance of the A...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199007000-00003
更新日期:1990-07-01 00:00:00
abstract::To determine the role of the parasympathetic system in the development of essential hypertension, the concentrations of acetylcholine (ACh) as a parasympathetic marker and norepinephrine (NE) as a sympathetic marker were measured simultaneously in the heart of spontaneously hypertensive rats (SHR) at 4, 10 and 27 week...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-198706000-00010
更新日期:1987-06-01 00:00:00
abstract:BACKGROUND:Childhood hypertension is an established predictor of adult hypertension and organ damage, an underestimated problem in developing countries. The aim of the study was to assess the prevalence of arterial hypertension, as well as the relationship of blood pressure values and weight class and urinary abnormali...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e3283407fe3
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that apelin protects against angiotensin II (Ang II)-induced cardiovascular fibrosis and vascular remodeling. METHODS AND RESULTS:Wild-type mice administered apelin or apelin along with Ang II exhibited less cardiovascular fibrosis and decreased plasminogen activator inhibitor type-1 (...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e32834347de
更新日期:2011-04-01 00:00:00
abstract::: Hypertension is a growing health concern worldwide. Established hypertension is a causative factor of heart failure, which is characterized by increased vascular resistance and intractable uncontrolled blood pressure. Hypertension and heart failure have multiple causes and complex pathophysiology but cellular immuni...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000002456
更新日期:2020-10-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/01.hjh.0000189868.48290.d8
更新日期:2005-12-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:
更新日期:1984-06-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract::Hypertension is associated with thickening of the wall of resistance vessels, but the cellular or genetic basis of this is unclear. Cell proliferation and intracellular alkalinization via increased Na+/H+ exchange are linked in the response of tissues to growth factors. To define a possible cellular basis for vascular...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-198906000-00006
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:In the past, different methods have been used to measure the carotid-femoral distance for the assessment of pulse wave velocity (PWV). However, the latest consensus published advises to use 80% of the direct straight carotid-femoral distance (D(0.8)) using either a flexible tape or a sliding c...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e32835e2a2f
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To determine the plasma cofactor which is required by diuretics (hydrochlorothiazide, chlorthalidone, indapamide, and furosemide) for direct vasorelaxant effects in vitro. DESIGN:A randomized, double-blind, vehicle-control design was used to avoid experimenter bias. METHODS:We plotted concentration-response...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199816060-00011
更新日期:1998-06-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 临床试验,杂志文章
doi:10.1097/HJH.0b013e32835f955c
更新日期:2013-06-01 00:00:00
abstract::Atrial natriuretic peptide (ANP) plays a pivotal role in modulation of vascular function and it is also involved in the pathophysiology of several cardiovascular diseases. We provide an updated overview of the current appraisal of ANP vascular effects in both animal models and humans. We describe the physiological imp...
journal_title:Journal of hypertension
pub_type: 杂志文章,评审
doi:10.1097/HJH.0b013e32835ed5eb
更新日期:2013-06-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000002709
更新日期:2020-12-09 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-200312000-00018
更新日期:2003-12-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e32834103ee
更新日期:2011-02-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
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更新日期:2019-10-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章,meta分析,评审
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更新日期:2014-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/HJH.0000000000002765
更新日期:2021-01-25 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/01.hjh.0000179908.51187.de
更新日期:2005-09-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e3282fb81c8
更新日期:2008-06-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e328360275d
更新日期:2013-05-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章,评审
doi:10.1097/01.hjh.0000173510.52987.68
更新日期:2005-07-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-200108000-00020
更新日期:2001-08-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-198312000-00010
更新日期:1983-12-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e3282f55049
更新日期:2008-05-01 00:00:00
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journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e32835731dd
更新日期:2012-09-01 00:00:00