Impaired insulin sensitivity in young, lean normotensive offspring of essential hypertensives: possible role of disturbed calcium metabolism.

abstract：OBJECTIVES:Calcium blockade has been reported to inhibit the contraction of the vascular smooth muscle and the liberation of vasoactive substances by endothelial cells. We tested the effects of calcium blockade on the mechanical properties of the carotid artery in normotensive Wistar-Kyoto (WKY) rats and spontaneously ...

journal_title：Journal of hypertension

authors： Lévy BI,el Fertak L,Pieddeloup C,Barouki F,Safar ME

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:Reflection of the finger pulse wave form is a valid measure of arterial stiffness, which may be continuously assessed during sleep. We investigated the relationships between sleep, sleep-disordered breathing, hypertension, and pulse propagation time (PPT) in patients with suspected sleep apnea. METHODS:The ...

journal_title：Journal of hypertension

authors： Svedmyr S,Zou D,Sommermeyer D,Ficker JH,Randerath W,Fietze I,Sanner B,Hedner J,Grote L

更新日期：2016-12-01 00:00:00

abstract：:The effects of age on the circadian blood pressure rhythm of patients with untreated essential hypertension (n = 133, World Health Organization stage I or II) were compared with those of normotensive subjects (n = 91). Subjects were classified into three groups by age: young (less than 40 years old), adult (40-59 year...

journal_title：Journal of hypertension

authors： Munakata M,Imai Y,Abe K,Sasaki S,Minami N,Hashimoto J,Sakuma H,Ichijo T,Yoshizawa M,Sekino H

更新日期：1991-05-01 00:00:00

abstract：:This study focuses on the relationship between some aspects of intra-erythrocytic sodium metabolism (intra-erythrocytic Na content, Na,Li-countertransport), blood pressure, and family history of hypertension, in a group of 84 randomly selected school children (45 males, 39 females). Na,Li-countertransport was signific...

journal_title：Journal of hypertension

authors： Trevisan M,Strazzullo P,Cappuccio FP,Di Muro MR,De Colle S,Franzese A,Iacone R,Krogh V

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVE:Increased BP-variability predicts cardiovascular morbidity and mortality in hypertensives. This study aimed to examine short-term BP-variability according to renal function stage. METHODS:We included 16 546 patients [10 270 (62.1%) without/6276 (38.9%) with CKD Stage 1-5] from the Spanish Ambulatory-Blood-Pr...

journal_title：Journal of hypertension

authors： Sarafidis PA,Ruilope LM,Loutradis C,Gorostidi M,de la Sierra A,de la Cruz JJ,Vinyoles E,Divisón-Garrote JA,Segura J,Banegas JR

更新日期：2018-05-01 00:00:00

abstract：:The response of blood pressure, heart rate and plasma catecholamines to a mental arithmetic and a cold pressor test was studied in 70 patients with mild essential hypertension and in 41 age- and sex-matched normotensives. Each group consisted of three prospectively stratified age classes: 20-29, 30-39 and 40-55 years....

journal_title：Journal of hypertension

authors： Lenders JW,Willemsen JJ,de Boo T,Lemmens WA,Thien T

更新日期：1989-04-01 00:00:00

abstract：:The contribution of deoxycorticosterone acetate (DOCA) and salt to arterial pressure and hypertension-related arterial wall changes was assessed in Wistar rats. One group of two-kidney DOCA-treated animals was given a high salt diet and another group a low salt diet. After 16 weeks of treatment, the animals on low sal...

journal_title：Journal of hypertension

authors： Cox RH

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVES:Some beta-blockers are less effective in reducing central blood pressure than other antihypertensive drugs, which may explain the higher rate of events in subjects randomized to atenolol in recent trials. We hypothesized that nebivolol, a mixed beta-blocker/nitro-vasodilator, would be more effective than ate...

journal_title：Journal of hypertension

authors： Dhakam Z,Yasmin,McEniery CM,Burton T,Brown MJ,Wilkinson IB

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:In arteries, agonists such as acetylcholine release an endothelium-derived hyperpolarizing factor (EDHF) that is neither nitric oxide nor prostacyclin. OBJECTIVES:To examine the responses to acetylcholine in segments of forearm veins from patients with chronic renal failure who either had never received dia...

journal_title：Journal of hypertension

authors： Martinez-León JB,Segarra G,Medina P,Vila JM,Lluch P,Peiró M,Otero E,Lluch S

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:The primary aim of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS) is to determine the effects of a long-term angiotensin converting enzyme (ACE)-inhibitor-based blood-pressure-lowering regimen on the risk of stroke among patients with a history of stroke or transient ischaemic attack (TI...

journal_title：Journal of hypertension

authors：

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Although 24-h urinary measure to estimate sodium and potassium excretion is the gold standard, it is not practical for large studies. We compared estimates of 24-h sodium and potassium excretion from a single morning fasting urine (MFU) using three different formulae in healthy individuals. M...

journal_title：Journal of hypertension

authors： Mente A,O'Donnell MJ,Dagenais G,Wielgosz A,Lear SA,McQueen MJ,Jiang Y,Xingyu W,Jian B,Calik KB,Akalin AA,Mony P,Devanath A,Yusufali AH,Lopez-Jaramillo P,Avezum A Jr,Yusoff K,Rosengren A,Kruger L,Orlandini A,Rangar

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) may lead to the development of hypertension and therapy with continuous positive airway pressure (CPAP) can promote reduction in blood pressure. OBJECTIVE:The objective of this study is to review systematically the effects of CPAP on blood pressure in patients with OSA. METHOD...

journal_title：Journal of hypertension

authors： Schein AS,Kerkhoff AC,Coronel CC,Plentz RD,Sbruzzi G

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE AND DESIGN:Remodelling in the media and decreases in connexin (Cx) expression and size of endothelial cells occur in the caudal artery of spontaneously hypertensive rats (SHR). The objective of this study was to determine whether similar changes are found in the aorta and whether effects in both aorta and cau...

journal_title：Journal of hypertension

authors： Rummery NM,Grayson TH,Hill CE

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:We aimed to determine the association of nonalcoholic fatty liver disease (NAFLD) with central and peripheral blood pressure (BP), in a general adolescent population and to examine whether associations are independent of adiposity. METHODS:Using cross-sectional data from a subsample (N = 1904) of a UK birth...

journal_title：Journal of hypertension

authors： Patel S,Lawlor DA,Ferreira DL,Hughes AD,Chaturvedi N,Callaway M,Day C,Sattar N,Fraser A

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Correlations have been found between oxidative stress and hypertension. OBJECTIVE:To determine whether antioxidants can normalize sympathetic dysfunction at pre- or postsynaptic levels in spontaneously hypertensive rats (SHRs). METHODS AND RESULTS:Untreated SHRs and Wistar-Kyoto (WKY) rats were compared wi...

journal_title：Journal of hypertension

authors： Girouard H,Chulak C,LeJossec M,Lamontagne D,de Champlain J

更新日期：2003-01-01 00:00:00

abstract：:The benefit of blood pressure-lowering therapy in individuals with normal blood pressure who are at high cardiovascular risk creates a challenge in how best to advocate such therapy. Arguments based on a putative causal role for blood pressure and the need to reduce blood pressure may be less likely to succeed than ar...

journal_title：Journal of hypertension

authors： Campbell DJ

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Some patients with essential hypertension manifest greater than normal urinary excretion of albumin (UAE). Authors of a few retrospective studies have suggested that there is an association between microalbuminuria and cardiovascular risk. OBJECTIVE:To evaluate whether microalbuminuria is associated with a ...

journal_title：Journal of hypertension

authors： Bigazzi R,Bianchi S,Baldari D,Campese VM

更新日期：1998-09-01 00:00:00

abstract：:Hypertension was induced in marmosets by ligating the minor branch of one renal artery. The blood pressure (BP), measured by a tail-cuff method, increased to hypertensive levels within 4-5 weeks and the maximum increases occurred after 4-15 weeks (BP, mean +/- s.e.m. was 120 +/- 3 and 152 +/- 6 mmHg before and 10 week...

journal_title：Journal of hypertension

authors： Neisius D,Wood JM

更新日期：1987-12-01 00:00:00

abstract：:Systolic blood pressure was measured on a total of 1855 occasions in 1307 children aged four and five years, and compared with values obtained since birth in the same children. There was a rapid rise in blood pressure in the first month of life. The mean blood pressure then only rose from 93 mmHg at six months to 98 m...

journal_title：Journal of hypertension

authors： de Swiet M,Fayers PM,Shinebourne EA

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence and risk markers of arterial hypertension in the context of a rapidly growing urbanization in Africa. DESIGN:A cross-sectional study was performed on a representative sample of inhabitants of Pikine, an urban suburb of Dakar, Senegal. METHODS:Blood pressure was measured by properly ...

journal_title：Journal of hypertension

authors： Astagneau P,Lang T,Delarocque E,Jeannee E,Salem G

更新日期：1992-09-01 00:00:00

abstract：:: The 2008 European Society of Cardiology/European Society of Hypertension guidelines recommend the first-line prescription of two antihypertensive drugs in single-pill combinations (SPCs), also known as fixed-dose combinations, for the treatment of most patients with hypertension. This recommendation is based on a la...

journal_title：Journal of hypertension

authors： Campana E,Cunha V,Glaveckaite S,Gruev I,Lamirault G,Lehmann E,Masi S,Mfeukeu Kuate L,Mishshenko L,Ona DID,Oo MZ,Tautu OGF,Vachulova A,Vintila AM,Wolf J,Zvartau N,Narkiewicz K,Laurent S

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND AND AIM:Ambulatory blood pressure monitoring (ABPM) is superior to conventional BP measurement in predicting outcome, with baseline 24-h, daytime and night-time absolute values, as well as relative nocturnal decline, as powerful determinants of prognosis. We aimed to evaluate ABPM estimates on the appearance...

journal_title：Journal of hypertension

authors： de la Sierra A,Banegas JR,Segura J,Gorostidi M,Ruilope LM,CARDIORISC Event Investigators.

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:In this randomized, double-blind, crossover study, the antihypertensive efficacy of amlodipine and nifedipine gastrointestinal therapeutic system (GITS) was compared following missed doses. Design and methods In a randomized crossover design, 42 patients were randomized to receive amlodipine (5-10 mg) or the ...

journal_title：Journal of hypertension

authors： Elliott HL,Elawad M,Wilkinson R,Singh SP

更新日期：2002-02-01 00:00:00

abstract：:The effects of essential fatty acid deficiency (EFAD) on vascular reactivity to vasoconstrictor stimuli were studied in rat autoperfused hindquarters. Weanling male Sprague-Dawley rats (aged 21 days) were fed diets containing 8% (weight/weight) of stearax plus 2% safflower oil (control diet) or 10% stearax (EFAD diet)...

journal_title：Journal of hypertension

authors： Kudo K,Dusting GJ,Loiacono RE,Sinclair AJ

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Hypertension in midlife has been associated with increased risk of stroke and neurocognitive decline. Few studies, however, have examined neurocognition among individuals with treatment-resistant hypertension or potential mechanisms by which treatment-resistant hypertension may impair neurocognition. METHOD...

journal_title：Journal of hypertension

authors： Smith PJ,Blumenthal JA,Hinderliter AL,Mabe SM,Schwartz JE,Avorgbedor F,Sherwood A

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To characterize the in vivo vascular properties of the spontaneously hypertensive rat (SHR) renal vascular bed by examining vascular conductance/resistance responsiveness to vasoactive agents in vivo and determining whether the filtration surface area of glomerular capillaries is reduced. DESIGN AND METHODS:...

journal_title：Journal of hypertension

authors： Kett MM,Bergström G,Alcorn D,Bertram JF,Anderson WP

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:The pathogenesis of nonalcoholic fatty liver disease (NAFLD) is multifactorial, and the presence of insulin resistance is recognized as the pathophysiological hallmark of this condition. Arterial hypertension is referred as an insulin-resistant state, and insulin resistance may substantially contribute to the...

journal_title：Journal of hypertension

authors： Fallo F,Dalla Pozza A,Sonino N,Federspil G,Ermani M,Baroselli S,Catena C,Soardo G,Carretta R,Belgrado D,Fabris B,Sechi LA

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:The physiopathological mechanisms implicated in hypertensive heart disease are multi-factorial, including myocyte hypertrophy, apoptosis and myocardial remodelling. In this process, some hormonal and local growth factors have a regulatory influence. The aim of this study was to evaluate the potential role of ...

journal_title：Journal of hypertension

authors： Fernández-Solà J,Borrisser-Pairó F,Antúnez E,Tobías E

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To assess the diagnostic accuracy of recommendations for self-monitoring blood pressure (BP) for diagnosing hypertension in primary care. METHODS:Two hundred and forty-seven consecutive participants with raised (≥130 mmHg systolic) BP measured by their general practitioner from four primary care practices in...

journal_title：Journal of hypertension

authors： Nunan D,Thompson M,Heneghan CJ,Perera R,McManus RJ,Ward A

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:The effect of nifedipine, a 1,4-dihydropyridine calcium antagonist, on the expression of monocyte chemoattractant protein 1 (MCP-1) induced by angiotensin II (Ang II) was examined using vascular smooth muscle cells (VSMC) isolated from rat thoracic aorta. METHODS AND RESULTS:Ang II increased the expression o...

journal_title：Journal of hypertension

authors： Wu L,Iwai M,Li Z,Li JM,Mogi M,Horiuchi M

更新日期：2006-01-01 00:00:00