Alterations in erythrocyte Na+,K+-cotransport in normal and hypertensive human pregnancy.

Abstract:

:Many physiological variables known or thought to affect erythrocyte Na+,K+-cotransport are altered in pregnancy. The interrelationships of Na+,K+-cotransport and pregnancy were therefore examined. Values were elevated by more than 30% in both second and third trimesters with a return towards non-pregnant levels in the postpartum period. Although pregnancy was also associated with elevated plasma cholesterol, renin activity and aldosterone, there was no significant relationship within the pregnant group between Na+,K+-cotransport and any of these factors. No change could be demonstrated in Na+,K+-cotransport values after 7 days of either high (greater than 250 mmol/day) or low (less than 50 mmol/day) sodium intake and values for those who developed pregnancy-associated hypertension (PAH, pre-eclampsia) were not significantly different from those in continuously normotensive women in either the second or the third trimesters of pregnancy.

journal_name

J Hypertens

journal_title

Journal of hypertension

authors

Gallery ED,Esber RP,Brown MA,Hawkins MR,Ross M

subject

Has Abstract

pub_date

1988-02-01 00:00:00

pages

153-8

issue

2

eissn

0263-6352

issn

1473-5598

journal_volume

6

pub_type

杂志文章
  • Aortic arch mechanics measured with two-dimensional speckle tracking echocardiography.

    abstract:PURPOSE:To study the feasibility of vascular mechanics at the aortic arch with two-dimensional speckle tracking echocardiography, as well as to define normal values and to compare results between hypertensive patients and healthy patients. METHODS:We included 107 patients (61 healthy patients and 46 hypertensive patie...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000001336

    authors: Teixeira R,Monteiro R,Baptista R,Pereira T,Ribeiro MA,Gonçalves A,Cardim N,Gonçalves L

    更新日期:2017-07-01 00:00:00

  • Apolipoprotein E polymorphism affects carotid artery atherosclerosis in smoking hypertensive men.

    abstract:OBJECTIVE:Smoking is a risk factor for increased carotid artery intima-media thickness (IMT). The apolipoprotein E (apoE) 4 allele has been associated with cardiovascular diseases, but the role of apoE in regard to intima-media thickness (IMT) has remained controversial. The objective was to investigate whether there i...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200212000-00015

    authors: Karvonen J,Kauma H,Kervinen K,Ukkola O,Rantala M,Päivänsalo M,Savolainen MJ,Kesäniemi YA

    更新日期:2002-12-01 00:00:00

  • Incidence of hypertension in individuals with different blood pressure salt-sensitivity: results of a 15-year follow-up study.

    abstract:OBJECTIVE:To evaluate the incidence of hypertension and the rate of decline in renal function in a sample of 47 Olivetti Heart Study (OHS) participants whose blood pressure (BP) salt-sensitivity and renal tubular sodium handling had been assessed in 1987-88. METHODS:During the 2002-04 OHS follow-up examination, medica...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e3281139ebd

    authors: Barba G,Galletti F,Cappuccio FP,Siani A,Venezia A,Versiero M,Della Valle E,Sorrentino P,Tarantino G,Farinaro E,Strazzullo P

    更新日期:2007-07-01 00:00:00

  • Chronic ouabain treatment exacerbates blood pressure elevation in spontaneously hypertensive rats: the role of vascular mechanisms.

    abstract:OBJECTIVE:Hypertensive rats are more sensitive to the pressor effects of acute ouabain than normotensive rats. We analyzed the effect of chronic ouabain (approximately 8.0 microg/day, 5 weeks) treatment on the blood pressure of spontaneously hypertensive rats (SHRs) and Wistar-Kyoto rats and the contribution of vascula...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e32832a391f

    authors: Xavier FE,Davel AP,Fukuda LE,Rossoni LV

    更新日期:2009-06-01 00:00:00

  • Sex differences in noninvasive vascular function in the community.

    abstract:OBJECTIVE:The relation of noninvasive vascular function to sex, sex hormones, and reproductive history in the general population is little understood. METHODS:We simultaneously assessed flow-mediated dilation (FMD) and peripheral arterial tonometry in 454 women (mean age 40.4±16.1 years, age range 19-78 years) and 100...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e328360f755

    authors: Schnabel RB,Biener MP,Wilde S,Sinning CR,Ojeda FM,Zeller T,Lubos E,Lackner KJ,Warnholtz A,Gori T,Espinola-Klein C,Blankenberg S,Munzel T,Wild PS

    更新日期:2013-07-01 00:00:00

  • Evaluation of elevated heart rate as a sympathetic nervous system biomarker in essential hypertension.

    abstract:BACKGROUND:There is a need for an easily accessible biomarker of sympathetic nervous activation in essential hypertension, but none exists. Heart rate (HR) has been suggested, but requires validation, now doubly important as an elevated HR in hypertension has emerged as an independent cardiovascular risk factor. METHO...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000002407

    authors: Esler M,Lambert G,Esler D,Ika Sari C,Guo L,Jennings G

    更新日期:2020-08-01 00:00:00

  • Salt intake in children 10-12 years old and its modification by active working practices in a school garden.

    abstract:OBJECTIVE:The aim of the study was to evaluate the 24-h urinary sodium excretion in children of 10-12 years at a school in the north of Portugal and to examine the influence on salt intake and blood pressure of three different educational interventions for 6 months. METHODS:Blood pressure (BP) and sodium excretion in ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e328363572f

    authors: Cotter J,Cotter MJ,Oliveira P,Cunha P,Polónia J

    更新日期:2013-10-01 00:00:00

  • A search for endogenous Na+,K+-ATPase inhibitor in acutely volume-expanded hog plasma led to lysophosphatidylcholine gamma-stearoyl.

    abstract::An Na+,K+-ATPase inhibitor possessing inhibitory activity against the specific binding of ouabain to Na+,K+-ATPase has been purified from the plasma of acutely saline-infused hogs. The purification was performed by a combination of Amberlite XAD-2 adsorption chromatography and five steps of high-pressure liquid chroma...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-198704000-00014

    authors: Tamura M,Inagami T,Kinoshita T,Kuwano H

    更新日期:1987-04-01 00:00:00

  • The GNB3 C825T polymorphism and essential hypertension: a meta-analysis of 34 studies including 14,094 cases and 17,760 controls.

    abstract:OBJECTIVES:The C825T single nucleotide polymorphism of the G-protein beta3 (GNB3) has been implicated in susceptibility to essential hypertension, through the expression of an alternatively spliced truncated variant. In an effort to clarify earlier inconclusive results, we performed a meta-analysis of population-based ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,meta分析

    doi:10.1097/HJH.0b013e328011db24

    authors: Bagos PG,Elefsinioti AL,Nikolopoulos GK,Hamodrakas SJ

    更新日期:2007-03-01 00:00:00

  • Influence of nebivolol and enalapril on metabolic parameters and arterial stiffness in hypertensive type 2 diabetic patients.

    abstract:OBJECTIVE:To compare the effects of a cardioselective beta-blocker (nebivolol) with those of an angiotensin-converting enzyme inhibitor (enalapril) on parameters of insulin sensitivity, peripheral blood flow and arterial stiffness during one extended glucose clamp experiment. DESIGN:A randomized, double-blind crossove...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.hjh.0000234121.48272.67

    authors: Kaiser T,Heise T,Nosek L,Eckers U,Sawicki PT

    更新日期:2006-07-01 00:00:00

  • Simultaneous radioimmunoassay of six angiotensin peptides in arterial and venous plasma of man.

    abstract::Using antibodies raised against angiotensin I and II, and high-performance liquid chromatography (HPLC) of plasma extracts, we have quantified six angiotensin peptides in venous (cubital vein) and arterial (brachial) plasma of normal male subjects. The concentrations of venous plasma (fmol/ml, mean +/- s.d., n = 29) f...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199002000-00011

    authors: Campbell DJ,Kladis A

    更新日期:1990-02-01 00:00:00

  • Intermedin1-53 protects against cardiac hypertrophy by inhibiting endoplasmic reticulum stress via activating AMP-activated protein kinase.

    abstract:OBJECTIVE:Intermedin (IMD), a novel member of the calcitonin/calcitonin gene-related peptide family, is involved in maintaining circulatory homeostasis and is a protective factor of heart and vessel. Here, we investigated the effects of IMD on cardiac hypertrophy in vivo and in vitro and explored the mechanisms involve...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000000597

    authors: Lu WW,Zhao L,Zhang JS,Hou YL,Yu YR,Jia MZ,Tang CS,Qi YF

    更新日期:2015-08-01 00:00:00

  • Enhanced platelet release of superoxide anion in systemic hypertension: role of AT1 receptors.

    abstract:BACKGROUND:Enhanced oxidative stress has been observed in hypertension, but the underlying mechanism has not been fully clarified. OBJECTIVE:To study the relationship between oxygen free radicals and hypertension, using platelets as a tool to measure the cellular production of superoxide anion (O2). DESIGN:Forty pati...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004872-200406000-00016

    authors: Germanò G,Sanguigni V,Pignatelli P,Caccese D,Lenti L,Ragazzo M,Lauro R,Violi F

    更新日期:2004-06-01 00:00:00

  • Impaired insulin sensitivity in young, lean normotensive offspring of essential hypertensives: possible role of disturbed calcium metabolism.

    abstract:OBJECTIVES:To determine whether insulin sensitivity is impaired in normotensive offspring of essential hypertensives and to investigate how it relates to disturbed calcium metabolism. DESIGN:In 10 young lean, normotensive subjects with family histories of essential hypertension and in 10 age-matched controls we invest...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199304000-00013

    authors: Ohno Y,Suzuki H,Yamakawa H,Nakamura M,Otsuka K,Saruta T

    更新日期:1993-04-01 00:00:00

  • Effects of changes in sodium balance on leucocyte sodium transport: qualitative differences in normotensive offspring of hypertensives and matched controls.

    abstract::To investigate the effects of changes in sodium balance on blood pressure and leucocyte sodium transport, normotensive first-degree relatives of hypertensive patients and control subjects were randomized to receive low- and high-salt diets for 2 weeks, separated by a wash-out period of 2 weeks. High-salt intake failed...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004872-198606000-00012

    authors: Heagerty AM,Alton SM,el-Ashry A,Bing RF,Thurston H,Swales JD

    更新日期:1986-06-01 00:00:00

  • Nisoldipine. Central haemodynamics at rest and during exercise in essential hypertension: acute and chronic studies.

    abstract::Calcium blockers may reduce contractility of vascular smooth muscle as well as that of myocardial cells. Therefore, falls in both total peripheral vascular resistance (TPR) and cardiac output (CO) might be responsible for a fall in blood pressure (BP) caused by calcium blockers in essential hypertension. We have studi...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章

    doi:

    authors: Omvik P,Lund-Johansen P,Haugland H

    更新日期:1988-02-01 00:00:00

  • Microalbuminuria screening by reagent strip predicts cardiovascular risk in hypertension.

    abstract:OBJECTIVE:We tested the hypothesis that qualitative microalbuminuria (MAU) screening in a practice setting would identify non-diabetic hypertensive patients at high risk of developing cardiovascular disease. DESIGN:We enrolled general practitioners throughout Germany, who obtained histories, physical examinations, and...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199602000-00011

    authors: Agrawal B,Berger A,Wolf K,Luft FC

    更新日期:1996-02-01 00:00:00

  • Enhanced blood pressure response to dietary salt in elderly women, especially those with small waist: hip ratio.

    abstract:OBJECTIVE:To determine the blood pressure responses in elderly normotensive men and women to dietary sodium and to the diunsaturated fatty acid dihomogammalinolenic acid (DGLA), which is derived from linoleic acid. DESIGN:Blood pressure responses were assessed in 66 subjects (36 male, 30 female; mean age 65 years) on ...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004872-199312000-00011

    authors: Nestel PJ,Clifton PM,Noakes M,McArthur R,Howe PR

    更新日期:1993-12-01 00:00:00

  • Elevated systolic blood pressure during recovery from exercise and the risk of sudden cardiac death.

    abstract:OBJECTIVE:The value of SBP during exercise and recovery period as a risk marker for sudden cardiac death (SCD) is not known. Thus, we assessed the association of SBP during recovery from exercise testing with the risk of SCD. METHODS:SBP was measured every 2 min during and at 2 min after a progressive cycle ergometer ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000000066

    authors: Laukkanen JA,Willeit P,Kurl S,Mäkikallio TH,Savonen K,Ronkainen K,Rauramaa R

    更新日期:2014-03-01 00:00:00

  • Determinants of blood pressure treatment and control in obese people: evidence from the general population.

    abstract:OBJECTIVE:We assessed hypertension prevalence, blood pressure (BP)-lowering treatment and control in obese adults compared with lean/normal-weight individuals in France. METHODS:Multistage stratified random sample of 2075 adults from the French Nutrition and Health Survey (ENNS), a cross-sectional national survey carr...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e3283593010

    authors: Czernichow S,Castetbon K,Salanave B,Vernay M,Barry Y,Batty GD,Hercberg S,Blacher J

    更新日期:2012-12-01 00:00:00

  • Prospective comparison of therapeutical attitudes in hypertensive type 2 diabetic patients uncontrolled on monotherapy. A randomized trial: the EDICTA study.

    abstract:OBJECTIVE:To compare the anti-hypertensive effect of combination therapy versus a single drug regimen schedule (dose-titration or switching to a different drug class) in type 2 diabetic hypertensive patients with inadequate blood pressure (BP) control on monotherapy. DESIGN:Prospective, randomized, open-fashion, paral...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004872-199917121-00022

    authors: Ruilope LM,de la Sierra A,Moreno E,Fernández R,Garrido J,de la Figuera M,de la Cámara AG,Coca A,Luque-Otero M

    更新日期:1999-12-01 00:00:00

  • Arterial stiffness in inflammatory bowel disease: a systematic review and meta-analysis.

    abstract:BACKGROUND:Arterial stiffness is increased with chronic inflammatory disorders. The reduction of inflammation by immunomodulatory therapy is associated with a restoration of arterial function. The aims of the study were to perform a meta-analysis to determine whether arterial stiffness is increased in patients with inf...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,meta分析

    doi:10.1097/HJH.0000000000000867

    authors: Zanoli L,Rastelli S,Granata A,Inserra G,Empana JP,Boutouyrie P,Laurent S,Castellino P

    更新日期:2016-05-01 00:00:00

  • Renal effects of fenoldopam in refractory hypertension.

    abstract::Fenoldopam, a dopamine-1 (D1) agonist, was administered by a 6-h intravenous infusion to patients with refractory hypertension [diastolic blood pressure (DBP) greater than 115 mmHg while on triple therapy] in order to achieve a fall in DBP of 30 mmHg. The evolution of blood pressure, heart rate, glomerular filtration ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-198808000-00010

    authors: Ruilope LM,Robles RG,Miranda B,Tovar J,Alcazar JM,Sancho J,Rodicio JL,Martinez A,Astorga A,Beck T

    更新日期:1988-08-01 00:00:00

  • Reference values and associated factors for Japanese newborns' blood pressure and pulse rate: the babies' and their parents' longitudinal observation in Suzuki Memorial Hospital on intrauterine period (BOSHI) study.

    abstract:OBJECTIVE:Currently, normative means and ranges of blood pressure (BP) and pulse rates in Japanese newborns are not available. The objective of the present study was to estimate BP, pulse rate, and their distribution among Japanese newborns. METHODS:Using oscillometric devices, arm or calf BP and pulse rate levels wer...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000000976

    authors: Satoh M,Inoue R,Tada H,Hosaka M,Metoki H,Asayama K,Murakami T,Mano N,Ohkubo T,Yagihashi K,Hoshi K,Suzuki M,Imai Y

    更新日期:2016-08-01 00:00:00

  • Angiotensin II type 2 receptor mediates sex differences in mice renal interlobar arteries response to angiotensin II.

    abstract:OBJECTIVE:Functional sex differences are described in several vascular beds. In the case of renal vessels, sex differences could influence processes like regulation of blood pressure and ion balance. Angiotensin II and nitric oxide are important regulators of renal vascular tone. Females have higher nitric oxide syntha...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e32835731dd

    authors: Viegas VU,Liu ZZ,Nikitina T,Perlewitz A,Zavaritskaya O,Schlichting J,Persson PB,Regitz-Zagrosek V,Patzak A,Sendeski MM

    更新日期:2012-09-01 00:00:00

  • Blood pressure in early adolescence in the offspring of preeclamptic and normotensive pregnancies.

    abstract:OBJECTIVE:To compare blood pressure (BP) in adolescence (11-12 years) among the offspring of preeclamptic and normotensive pregnancies. METHOD:SBP and DBP of 181 girls and boys born after pregnancies with preeclampsia were measured and compared with the BP of 356 age-matched girls and boys of normotensive pregnancies....

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e328330052a

    authors: Øglaend B,Forman MR,Romundstad PR,Nilsen ST,Vatten LJ

    更新日期:2009-10-01 00:00:00

  • The calcium-channel blocker lacidipine reduces the development of atherosclerotic lesions in the apoE-deficient mouse.

    abstract:BACKGROUND:Lacidipine is a widely used calcium-channel blocker, which has both long-lasting antihypertensive activity and also antioxidant properties. Previous studies have demonstrated the ability of lacidipine to reduce the development of atherosclerotic lesions in several animal models. OBJECTIVE:The present study ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200018100-00010

    authors: Cristofori P,Lanzoni A,Quartaroli M,Pastorino AM,Zancanaro C,Cominacini L,Gaviraghi G,Turton J

    更新日期:2000-10-01 00:00:00

  • Renal protective effects of chronic exercise and antihypertensive therapy in hypertensive rats with chronic renal failure.

    abstract:OBJECTIVES:Patients with chronic renal failure are restricted to mild physical activity and tend to a lack of exercise. However, there have been few reports regarding the influence of chronic exercise on the progression of renal disease. Similarly, there are few animal models concerned with the effect of exercise train...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200110000-00024

    authors: Kohzuki M,Kamimoto M,Wu XM,Xu HL,Kawamura T,Mori N,Nagasaka M,Kurosawa H,Minami N,Kanazawa M,Saito T,Yoshida K

    更新日期:2001-10-01 00:00:00

  • Linear periodization of strength training in blocks attenuates hypertension and diastolic dysfunction with normalization of myocardial collagen content in spontaneously hypertensive rats.

    abstract:BACKGROUND AND METHOD:This study evaluated the effects of a linear block strength training programme on the parameters of cardiac remodelling in spontaneously hypertensive rats. Thirty-nine rats were equally distributed in four groups: normotensive sedentary, normotensive trained, hypertensive sedentary and hypertensiv...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000002188

    authors: Perilhão MS,Krause Neto W,da Silva AA,Alves LLS,Antonio EL,Medeiros A,Rica RL,Serra AJ,Tucci PJF,Bocalini DS

    更新日期:2020-01-01 00:00:00

  • Can the blood pressure predict cognitive task performance in a healthy population sample?

    abstract:OBJECTIVES:To study the relation between the blood pressure and the neurocognitive function within the full adult age range in a large population sample. DESIGN:A cross-sectional study of 936 healthy adults who were recruited from a register of family practices, stratified for age (24-81 years), sex, and occupational ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199715100-00004

    authors: van Boxtel MP,Gaillard C,Houx PJ,Buntinx F,de Leeuw PW,Jolles J

    更新日期:1997-10-01 00:00:00