Blood pressure in early adolescence in the offspring of preeclamptic and normotensive pregnancies.

Abstract:

OBJECTIVE:To compare blood pressure (BP) in adolescence (11-12 years) among the offspring of preeclamptic and normotensive pregnancies. METHOD:SBP and DBP of 181 girls and boys born after pregnancies with preeclampsia were measured and compared with the BP of 356 age-matched girls and boys of normotensive pregnancies. The association of preeclampsia with later BP was adjusted for perinatal information, anthropometric factors at follow-up, and maternal BP and BMI. RESULTS:In the preeclampsia group, SBP in early adolescence was higher than in the normotensive group (115.3 vs. 113.5 mmHg, P = 0.03), but there was no difference in DBP (66.4 vs. 65.3 mmHg, P = 0.10). After adjustment for maternal body mass and BP, the difference in SBP was largely attenuated. CONCLUSION:The higher SBP among adolescent offspring of preeclamptic pregnancies could be mediated by maternal body mass or BP, factors that are positively associated with the risk of preeclampsia in pregnancy.

journal_name

J Hypertens

journal_title

Journal of hypertension

authors

Øglaend B,Forman MR,Romundstad PR,Nilsen ST,Vatten LJ

doi

10.1097/HJH.0b013e328330052a

subject

Has Abstract

pub_date

2009-10-01 00:00:00

pages

2051-4

issue

10

eissn

0263-6352

issn

1473-5598

journal_volume

27

pub_type

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