Dietary sodium and pulse pressure in normotensive and essential hypertensive subjects.

abstract：BACKGROUND:Hypertension in midlife has been associated with increased risk of stroke and neurocognitive decline. Few studies, however, have examined neurocognition among individuals with treatment-resistant hypertension or potential mechanisms by which treatment-resistant hypertension may impair neurocognition. METHOD...

journal_title：Journal of hypertension

authors： Smith PJ,Blumenthal JA,Hinderliter AL,Mabe SM,Schwartz JE,Avorgbedor F,Sherwood A

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:Angiotensin (Ang) II increases reactive oxygen species (ROS), decreases nitric oxide (NO) bioavailability and promotes cardiovascular remodeling. ROS have been identified as critical second messengers of the trophic responses by Ang II. In rats with Ang II-induced hypertension, we investigated the role of ROS...

journal_title：Journal of hypertension

authors： Zhou MS,Jaimes EA,Raij L

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:Different radiologists may show considerable variation in their interpretation of renal angiograms. We therefore wished to establish the reliability of their interpretation. DESIGN:Assessment of the intra- and inter-observer agreement of the interpretation of renal angiograms. SETTING:Tertiary referral univ...

journal_title：Journal of hypertension

authors： Schreij G,de Haan MW,Oei TK,Koster D,de Leeuw PW

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:The pteridine cofactor tetrahydrobiopterin (BH4) has emerged as a critical determinant of endothelial nitric oxide synthase (eNOS) activity. When BH4 availability is limited, eNOS does not produce nitric oxide (NO) but instead generates superoxide. BH4 may reverse endothelial dysfunction due to cardiovascular...

journal_title：Journal of hypertension

authors： Kase H,Hashikabe Y,Uchida K,Nakanishi N,Hattori Y

更新日期：2005-07-01 00:00:00

abstract：:Nitric oxide formed by neuronal nitric oxide synthase (nNOS) in the brain, autonomic inhibitory (nitrergic) nerves, and heart plays important roles in the control of blood pressure. Activation of nitrergic nerves innervating the systemic vasculature elicits vasodilatation, decreases peripheral resistance, and lowers b...

journal_title：Journal of hypertension

authors： Toda N,Ayajiki K,Okamura T

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Coffee is widely consumed in the Western diet and therefore has important implications for public health. Research findings pertaining to the effects of coffee consumption on cardiovascular health are conflicting, and the role of caffeine is not clear. OBJECTIVE:To examine the relationship between coffee in...

journal_title：Journal of hypertension

authors： Hamer M,Williams ED,Vuononvirta R,Gibson EL,Steptoe A

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) has several negative effects on the heart including increase in myocardial end-systolic stress, venous return and sympathetic activity, all potential stimuli of left ventricular (LV) hypertrophy. The impact of the severity of OSA on LV geometry is unknown. We hypothesized that O...

journal_title：Journal of hypertension

authors： Cioffi G,Russo TE,Stefenelli C,Selmi A,Furlanello F,Cramariuc D,Gerdts E,de Simone G

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The sleep apnea syndrome (SAS) is a common health problem with a 30% prevalence among patients with so-called essential hypertension. OBJECTIVE:Prompted by this epidemiologic link we tried to find out whether there is a cause-effect relationship between SAS and systemic hypertension. DESIGN:We developed an...

journal_title：Journal of hypertension

authors： Lesske J,Fletcher EC,Bao G,Unger T

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVES:Renal denervation (RDN) can reduce sympathetic activity and blood pressure (BP) in patients with hypertension. The effects on resting and ambulatory heart rate (HR), also regulated by the sympathetic nervous system, are not established. METHODS:Herein, we report 12-month outcomes from the Global SYMPLICITY ...

journal_title：Journal of hypertension

authors： Böhm M,Ukena C,Ewen S,Linz D,Zivanovic I,Hoppe U,Narkiewicz K,Ruilope L,Schlaich M,Negoita M,Schmieder R,Williams B,Zeymer U,Zirlik A,Mancia G,Mahfoud F,Global SYMPLICITY Registry Investigators.

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:Functional sex differences are described in several vascular beds. In the case of renal vessels, sex differences could influence processes like regulation of blood pressure and ion balance. Angiotensin II and nitric oxide are important regulators of renal vascular tone. Females have higher nitric oxide syntha...

journal_title：Journal of hypertension

authors： Viegas VU,Liu ZZ,Nikitina T,Perlewitz A,Zavaritskaya O,Schlichting J,Persson PB,Regitz-Zagrosek V,Patzak A,Sendeski MM

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:Construction of prognostically relevant endpoints for clinical trials in hypertension has increasingly included coronary revascularization with myocardial infarction (MI) as manifestations of coronary artery disease. However, whether coronary revascularization and MI predict other cardiovascular events simila...

journal_title：Journal of hypertension

authors： Cicala S,de Simone G,Gerdts E,Dahlöf B,Lindholm LH,Kjeldsen SE,Devereux RB

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Studies have shown that famine exposure during early life may increase the risk of cardiovascular disease (CVD), hypertension, and diabetes during adulthood. We aimed to assess whether exposure to the Chinese famine (1959-1961) modifies the association between hypertension and CVD. METHODS:We investigated da...

journal_title：Journal of hypertension

authors： Shi Z,Nicholls SJ,Taylor AW,Magliano DJ,Appleton S,Zimmet P

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To study 24-h ambulatory blood pressure (BP) and development of hypertension over four decades in women with childhood urinary tract infection (UTI) associated with renal damage. METHODS:A population-based group of 111 women was followed from their first UTI in childhood. The cohort was investigated at a med...

journal_title：Journal of hypertension

authors： Gebäck C,Hansson S,Himmelmann A,Sandberg T,Sixt R,Jodal U

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:Phenotypic transformation of adventitial fibroblasts is important in the pathogenesis of hypertension. This study was designed to determine whether fibronectin type III domain containing 5 (FNDC5) alleviates the phenotypic transformation of adventitial fibroblasts in hypertension and the underlying mechanisms...

journal_title：Journal of hypertension

authors： Ling L,Chen D,Tong Y,Zang YH,Ren XS,Zhou H,Qi XH,Chen Q,Li YH,Kang YM,Zhu GQ

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Recent studies have demonstrated that stimulating autoantibodies against the angiotensin II type 1 receptor (AT1R-AA) are frequently detected in the sera from women with preeclampsia, suggesting that they may play an important role in the pathogenesis of this disease. Nevertheless, the real clinical significa...

journal_title：Journal of hypertension

authors： Leaños-Miranda A,Campos-Galicia I,Alvarez-Jiménez G,Isordia-Salas I,Rivera-Leaños R,Ulloa-Aguirre A

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To describe several emerging concepts regarding the biosynthesis, metabolism and biological roles of adenosine and to illustrate the possible significance of these ideas to vascular biology by proposing a hypothesis pertaining to the role of erythrocyte-derived adenosine deaminase in vaso-occlusive diseases a...

journal_title：Journal of hypertension

authors： Jackson EK,Koehler M,Mi Z,Dubey RK,Tofovic SP,Carcillo JA,Jones GS

更新日期：1996-01-01 00:00:00

abstract：:Ca2+ pump kinetics were investigated in erythrocytes from 22 essential hypertensive patients and 20 normotensive controls (under initial-rate and steady-state conditions, using Sr2+ as a Ca2+ analogue). The mean value of the apparent dissociation constant for total internal Ca2+ (KCa) was slightly but significantly in...

journal_title：Journal of hypertension

authors： de la Sierra A,Hannaert P,Ollivier JP,Senn N,Garay R

更新日期：1990-03-01 00:00:00

abstract：OBJECTIVE:Prior to the discovery of chloride channel Kb with a variant threonine change to serine at position 481 (CLCNKB-T481S) there were no variants or clinical disorders associated with gain-of-function defects in thick ascending limb of the kidney channels or transporters. CLCNKB-T481S is a novel gain-of-function ...

journal_title：Journal of hypertension

authors： Sile S,Velez DR,Gillani NB,Narsia T,Moore JH,George AL Jr,Vanoye CG,Williams SM

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:The contribution of salt intake to the pathogenesis of hypertension holds longstanding interest. Recent studies employed the sensitivity of blood pressure (BP) to salt intake as an intermediate phenotype. The validity of this approach relative to the homogeneity of sodium-sensitive hypertension was investigat...

journal_title：Journal of hypertension

authors： Hurwitz S,Fisher ND,Ferri C,Hopkins PN,Williams GH,Hollenberg NK

更新日期：2003-05-01 00:00:00

abstract：PURPOSE:Cardiovascular reactivity to mental stress has been used as a tool to predict short-term hypertension risk in adults but the impact of cardiovascular reactivity in childhood on hypertension in adulthood is unknown. Using the 1970 British Cohort study, we examined the association between pulse rate reactivity in...

journal_title：Journal of hypertension

authors： Hamer M,Kivimäki M,Batty GD

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:Studies directly comparing the associations of intima-media thickness with blood pressure (BP) on manual sphygmomanometric blood pressure measurement (SBPM) and 24-h ambulatory blood pressure measurement (ABPM) are scarce and have a cross-sectional design. METHODS:At baseline, we measured systolic and diasto...

journal_title：Journal of hypertension

authors： Dechering DG,Wizner B,Adiyaman A,Nawrot T,Jin Y,Richart T,Kuznetsova T,Struijker-Boudier HA,Thien T,Staessen JA

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Recent reports have demonstrated increased cardiac risk, and an association with essential hypertension in patients with panic disorder. The cause is not known, but possibly involves sympathetic nervous activation. In this study, we evaluated the arterial baroreflex control of vascular sympathetic nervous ou...

journal_title：Journal of hypertension

authors： Lambert EA,Thompson J,Schlaich M,Laude D,Elghozi JL,Esler MD,Lambert GW

更新日期：2002-12-01 00:00:00

abstract：:Systolic (SBP), diastolic (DBP) and mean [MBP = diastolic + 1/3 (systolic - diastolic)] blood pressures were compared as predictors of all causes of death (ALL) and of deaths from atherosclerotic cardiovascular disease (ACVD) in 2480 men, aged 40-59 years, belonging to three cohorts followed up for 20 years. Both univ...

journal_title：Journal of hypertension

authors： Menotti A,Seccareccia F,Giampaoli S,Giuli B

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:To assess the effect of orlistat plus diet compared with diet alone in promoting weight loss and blood pressure reduction in hypertensive, overweight/obese patients. DESIGN:A pragmatic randomized, controlled trial. SETTING:Hypertension clinic of a university hospital. PATIENTS:Hypertensive patients aged 18...

journal_title：Journal of hypertension

authors： Bloch KV,Salles GF,Muxfeldt ES,Da Rocha Nogueira A

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVES:Endothelial dysfunction is associated to cardiovascular risk factors and predicts cardiovascular events. Peripheral arterial tonometry (PAT) is a novel noninvasive method to assess endothelial function. However, there is a paucity of data about its reproducibility. The aim of this study was to assess the fea...

journal_title：Journal of hypertension

authors： Brant LC,Barreto SM,Passos VM,Ribeiro AL

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:The present study was designed to investigate the effect of nicardipine administration upon systolic blood pressure (SBP) and cardiac hypertrophy in spontaneously hypertensive rats (SHR). DESIGN:SBP, heart: and left ventricle: body weight ratios, the cross-sectional area of cardiocytes, and the ultrastructur...

journal_title：Journal of hypertension

authors： Ferrante F,Bronzetti E,Ciriaco E,Felici L,Amenta F

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVE:Low insulin sensitivity is closely related to both cardiovascular diseases and diabetes development. Still, correlates of insulin sensitivity have mainly been examined in cross-sectional studies. As far as we are aware, the longitudinal stability of insulin sensitivity in young men is largely unknown. We aime...

journal_title：Journal of hypertension

authors： Skårn SN,Flaa A,Kjeldsen SE,Rostrup M,Brunborg C,Reims HM,Fossum E,Høieggen A,Aksnes TA

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:There is ongoing discussion on how best to screen for diabetes mellitus. Previous studies suggest that an abnormal oral glucose tolerance test (OGTT) is better than fasting glucose levels in predicting cardiovascular mortality, which is largely determined by macrovascular complications in type 2 diabetes. We ...

journal_title：Journal of hypertension

authors： Schneider MP,Ott C,Ritt M,Raff U,Schlaich MP,Schmieder RE

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:It is well known that among hypertensive patients, an increased left ventricular mass (LVM) is a powerful predictor of cardiovascular morbidity and mortality. However, the mechanisms underlying LVM in hypertension are not completely understood, as the absolute value of blood pressure and other risk factors a...

journal_title：Journal of hypertension

authors： Menni C,Boffi L,Cesana F,Viviani Anselmi C,Nava S,Bertola F,Blasio AM,Roncarati R,Trimarco V,Marino M,Trimarco B,Grassi G,Giannattasio C,Mancia G

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:To investigate whether the combination of exercise training with the angiotensin-converting enzyme inhibitor lisinopril will have an additional beneficial effect on left ventricular function in spontaneously hypertensive rats. DESIGN:Twelve-week-old male rats were assigned to treadmill running (Ht-Ex; 20 m/...

journal_title：Journal of hypertension

authors： Ziada AM

更新日期：2009-06-01 00:00:00