Enhanced platelet release of superoxide anion in systemic hypertension: role of AT1 receptors.

abstract：OBJECTIVES:Evidence about sex differences in blood pressure (BP) at the time of acute stroke presentation is scarce. We aimed to summarize available data on sex differences in BP at the time of acute stroke presentation, including stratification by prior history of hypertension and stroke subtype. METHODS:We performed...

journal_title：Journal of hypertension

authors： Li J,Yang SC,Moullaali TJ,Chen R,Woodward M,Carcel C,Delcourt C,Sandset EC,Anderson C,Chen G,Wang X

更新日期：2019-10-01 00:00:00

abstract：:Systemic and regional haemodynamic effects of renal denervation were evaluated in adult (six-month-old) male spontaneously hypertensive rats (SHR) using the Fick procedure and electromagnetic flowmetry technique. Renal denervation (bilateral, 10% phenol in ethanol), performed five to eight days before the experiment, ...

journal_title：Journal of hypertension

authors： Lee JY,Walsh GM

更新日期：1983-12-01 00:00:00

abstract：OBJECTIVE:Endothelin is thought to be related to cardiovascular disease. The purpose of this study was to determine whether endothelin levels could be reduced by a calcium antagonist and a 'natural factor'. DESIGN:Since calcium ionophores can induce endothelin-1 messenger RNA synthesis in cultured endothelial cells, t...

journal_title：Journal of hypertension

authors： Liu JJ,Casley D,Wojta J,Gallicchio M,Dauer R,Buxton BF,Johnston CI

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVES:Night-time blood pressure (BP) - prognostically more important than circadian BP variability - has not been evaluated for quantitative associations with objective sleep quality in large populations. METHODS:The cross-sectional study measured actigraphic sleep parameters and night-time BP for two nights in 1...

journal_title：Journal of hypertension

authors： Oume M,Obayashi K,Asai Y,Ogura M,Takeuchi K,Tai Y,Kurumatani N,Saeki K

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of angiotensins acting at the rostral ventrolateral medulla (RVLM) on the cardiovascular adjustments following haemorrhage. DESIGN:Changes in mean arterial pressure (MAP) and heart rate (HR) produced by micro-injections of angiotensin II (Ang II) and angiotensin (Ang)-(1-7) and differ...

journal_title：Journal of hypertension

authors： Lima DX,Campagnole-Santos MJ,Fontes MA,Khosla MC,Santos RA

更新日期：1999-08-01 00:00:00

abstract：:The relationships between five erythrocyte cation transport systems (Na(+)-K+ pump, Na(+)-K+ cotransport, Na(+)-Li+ countertransport and Na+ and K+ passive permeabilities) and plasma lipids (total plasma cholesterol, high-density lipoprotein cholesterol and triglycerides) were investigated in 129 male adult subjects w...

journal_title：Journal of hypertension

authors： Hajem S,Moreau T,Hannaert P,Lellouch J,Orssaud G,Huel G,Claude JR,Garay RP

更新日期：1990-10-01 00:00:00

abstract：:Behavioral stress and high dietary salt have been reported to increase blood pressure additively in non-human primates. This study was designed to replicate this phenomenon and to assess neuroendocrine correlates and responses to two commonly used antihypertensives, a beta-adrenoceptor blocker and a thiazide diuretic....

journal_title：Journal of hypertension

authors： Turkkan JS,Goldstein DS

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:Using an aortic constriction model in mice, we studied whether the increase in pressure or the activation of the renin-angiotensin system (RAS) and its main receptors is the main driving force for plaque progression. METHODS:Male ApoE mice underwent sham surgery or placement of a suprarenal silver clip aroun...

journal_title：Journal of hypertension

authors： Johansson ME,Wickman A,Skøtt O,Gan LM,Bergström G

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on pneumonia hospitalization in patients with stroke history in Taiwan. METHODS:We conducted a case-crossover study using the National Health Insurance Research Database in Taiwan during the period from...

journal_title：Journal of hypertension

authors： Liu CL,Shau WY,Wu CS,Lai MS

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To examine the influence of genetic factors on plasma leptin levels. SUBJECTS AND METHODS:We measured plasma leptin levels, body mass index and body fat distribution in healthy young female monozygotic (n = 19) and dizygotic (n = 14) twins. The twin zygosity was verified by determination of short tandem repe...

journal_title：Journal of hypertension

authors： Narkiewicz K,Szczech R,Winnicki M,Chrostowska M,Pawlowski R,Lysiak-Szydlowska W,Choe I,Kato M,Sivitz WI,Krupa-Wojciechowska B,Somers VK

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVES:Arterial stiffness is associated with excess morbidity and mortality, independently of other cardiovascular risk factors. Age is the main determinant responsible for arterial wall changes leading to arterial stiffening. Environmental and genetic factors may however influence the magnitude of the effects of a...

journal_title：Journal of hypertension

authors： Lajemi M,Labat C,Gautier S,Lacolley P,Safar M,Asmar R,Cambien F,Benetos A

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVES:To investigate whether the combination of exercise training with the angiotensin-converting enzyme inhibitor lisinopril will have an additional beneficial effect on left ventricular function in spontaneously hypertensive rats. DESIGN:Twelve-week-old male rats were assigned to treadmill running (Ht-Ex; 20 m/...

journal_title：Journal of hypertension

authors： Ziada AM

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:The increase in blood pressure that accompanies the obese state is almost invariably associated with alterations in metabolism (insulin resistance and dyslipidaemia) and the neurohumoral profile (activation of the renin-angiotensin system, sympathetic overactivity), which potentiate the cardiovascular risk as...

journal_title：Journal of hypertension

authors： Grassi G,Seravalle G,Dell'Oro R,Trevano FQ,Bombelli M,Scopelliti F,Facchini A,Mancia G,CROSS Study.

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the 24-h urinary sodium excretion in children of 10-12 years at a school in the north of Portugal and to examine the influence on salt intake and blood pressure of three different educational interventions for 6 months. METHODS:Blood pressure (BP) and sodium excretion in ...

journal_title：Journal of hypertension

authors： Cotter J,Cotter MJ,Oliveira P,Cunha P,Polónia J

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Hydroxymethylglutaryl coenzyme A (HMGCoA) reductase inhibitors have beneficial effects beyond their cholesterol-lowering properties. The antioxidant mechanism of HMGCoA reductase inhibitors is not completely understood. OBJECTIVES:To elucidate the antioxidant effect of simvastatin. METHODS:We studied the i...

journal_title：Journal of hypertension

authors： Carneado J,Alvarez de Sotomayor M,Perez-Guerrero C,Jimenez L,Herrera MD,Pamies E,Martin-Sanz MD,Stiefel P,Miranda M,Bravo L,Marhuenda E

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:The main objective was to examine the role of hemodynamics in rat aortic and left ventricular hypertrophy produced by sinoaortic denervation (SAD). DESIGN AND METHODS:Rats were examined at different times after SAD or sham operation (Sham). Hemodynamics were recorded continuously in conscious unrestrained ra...

journal_title：Journal of hypertension

authors： Miao CY,Su DF

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVES:Aldosterone is synthesized in extra-adrenal tissues such as the vasculature, heart and brain. The mechanisms underlying the effect of high salt intake on the development and acceleration of vascular injury and cardiac hypertrophy in the stroke-prone spontaneously hypertensive rats (SHRSP) are still not clear...

journal_title：Journal of hypertension

authors： Takeda Y,Yoneda T,Demura M,Furukawa K,Miyamori I,Mabuchi H

更新日期：2001-03-01 00:00:00

abstract：:Over the last few years, much progress has been made in understanding the genetic basis of primary aldosteronism. This has led to the diagnosis of the familial forms and has aided the understanding of the basis of sporadic forms of the disease. Such information can be exploited to improve the therapeutic approaches us...

journal_title：Journal of hypertension

authors： Mulatero P,Morello F,Veglio F

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:The genetic background of orthostatic hypotension, an important risk factor for future cardiovascular morbidity and mortality, was investigated. DESIGN AND METHODS:The study subjects comprised 415 community-dwelling individuals, who were free from any cardiovascular complications, aged 50 years or older (mea...

journal_title：Journal of hypertension

authors： Tabara Y,Kohara K,Miki T

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:The relationship between sodium intake and cardiovascular events is controversial, but most large epidemiological studies estimated sodium intake using formulae based on single urine samples, the validity of which is debated. We evaluated sodium intake estimating formulae in a large cohort of adult patients. ...

journal_title：Journal of hypertension

authors： Vidal-Petiot E,Joseph A,Resche-Rigon M,Boutten A,Mullaert J,d' Ortho MP,Vrtovsnik F,Steg PG,Flamant M

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Constitutional hypotension (CHT) is defined as a SBP below 105 mmHg. As autonomic-related symptoms are frequently reported in CHT, these symptoms suggest that the cardiovascular autonomic control is perturbed in individuals with CHT. METHODS:We investigated the autonomic cardiovascular control of 15 women w...

journal_title：Journal of hypertension

authors： Jacob G,Barbic F,Glago M,Dipaola F,Porta A,Furlan R

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between stroke risk and blood pressure (BP) levels with regard to the usage of antihypertensive medications. METHODS:From the Japan arteriosclerosis longitudinal study, 11,371 participants from the four population-based cohort studies (aged 40-89) were followed up for a mean of 9....

journal_title：Journal of hypertension

authors： Asayama K,Ohkubo T,Yoshida S,Suzuki K,Metoki H,Harada A,Murakami Y,Ohashi Y,Ueshima H,Imai Y,Japan Arteriosclerosis Longitudinal Study (JALS) group.

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Vascular and lung function develop and decline over the life course; both predict cardiovascular events and mortality but little is known of how they develop over time. We analysed their relationship in a multiethnic cohort study to test whether lung function from early adolescence to young adulthood affecte...

journal_title：Journal of hypertension

authors： Lu Y,Sooky L,Silva MJ,Molaodi OR,Karamanos A,Cruickshank JK,Harding S

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Left ventricular mass is associated with body size, obesity and blood pressure. Echocardiography is routinely used to estimate this parameter, which is usually indexed to body surface area to allow comparisons to be made between individuals and groups of different body size. However, in obese subjects, using...

journal_title：Journal of hypertension

authors： Whalley GA,Gamble GD,Doughty RN,Culpan A,Plank L,MacMahon S,Sharpe N

更新日期：1999-04-01 00:00:00

abstract：:Noradrenergic activity was measured in the brainstem, hypothalamus and thoracic spinal cord of male and female spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats at 6 and 28-36 weeks of age. Two techniques were used, measurement of a major noradrenaline (NA) metabolite, free 3,4-dihydroxyphenylethyleneglycol...

journal_title：Journal of hypertension

authors： Howes LG,Summers RJ,Rowe PR,Louis WJ

更新日期：1985-06-01 00:00:00

abstract：OBJECTIVES:We hypothesized that addressing the 24-h relationship between RR interval and systolic arterial pressure (SAP) during ambulatory blood pressure monitoring could detect alterations in circadian arterial pressure and heart rate profile and could also be linked to the ambulatory arterial stiffness index. METHO...

journal_title：Journal of hypertension

authors： Pizzinelli P,Iellamo F,Beltrami S,Lucini D,Pagani M

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:Optimal medication use obscures the impact of physical activity on traditional cardiometabolic risk factors. We evaluated the relationship between step counts and carotid-femoral pulse wave velocity (cfPWV), a summative risk indicator, in patients with type 2 diabetes and/or hypertension. RESEARCH DESIGN AND...

journal_title：Journal of hypertension

authors： Dasgupta K,Rosenberg E,Joseph L,Trudeau L,Garfield N,Chan D,Sherman M,Rabasa-Lhoret R,Daskalopoulou SS

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:We aimed to determine the association of nonalcoholic fatty liver disease (NAFLD) with central and peripheral blood pressure (BP), in a general adolescent population and to examine whether associations are independent of adiposity. METHODS:Using cross-sectional data from a subsample (N = 1904) of a UK birth...

journal_title：Journal of hypertension

authors： Patel S,Lawlor DA,Ferreira DL,Hughes AD,Chaturvedi N,Callaway M,Day C,Sattar N,Fraser A

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To investigate the rate of albumin excretion and the prevalence of albuminuria in hypertensive individuals relative to the normotensive population, and to clarify the quantitative importance of confounding variables. DESIGN AND METHODS:We examined the morning urines of all consecutive non-diabetic and diabet...

journal_title：Journal of hypertension

authors： Hörner D,Fliser D,Klimm HP,Ritz E

更新日期：1996-05-01 00:00:00

abstract：:Precapillary resistance arteries from spontaneously hypertensive rats (SHR) and Wistar-Kyoto normotensive rats (WKY) were found to contain three inositol lipids and to produce five inositol phosphate peaks. These were assessed by a highly sensitive procedure which involved the separation of radiolabelled inositol-cont...

journal_title：Journal of hypertension

authors： Durkin H,Ollerenshaw JD,Heagerty AM

更新日期：1990-06-01 00:00:00