Objective sleep quality and night-time blood pressure in the general elderly population: a cross-sectional study of the HEIJO-KYO cohort.

Abstract:

OBJECTIVES:Night-time blood pressure (BP) - prognostically more important than circadian BP variability - has not been evaluated for quantitative associations with objective sleep quality in large populations. METHODS:The cross-sectional study measured actigraphic sleep parameters and night-time BP for two nights in 1101 elderly participants. RESULTS:Mean age of the participants was 71.8 years, and mean night-time SBP and DBP were 115.9 ± 16.2 and 66.9 ± 8.4 mmHg, respectively. Multivariable analysis controlling for potential confounders revealed that the lowest sleep efficiency quartile group exhibited significantly higher night-time SBP and DBP than the highest quartile group [mean difference: SBP, 4.7 mmHg, 95% confidence interval (CI), 2.0-7.3; DBP, 2.3 mmHg, 95% CI 0.9-3.7]. The longest wake after sleep onset and sleep-onset latency quartile groups exhibited significantly higher night-time SBP (3.1 mmHg, 95% CI 0.3-5.9 and 3.4 mmHg, 95% CI 0.8-6.0) and DBP (2.0 mmHg, 95% CI 0.5-3.5 and 1.9 mmHg 95% CI 0.5-3.3), respectively, than the shortest quartile group. Significantly lower night-time SBP (3.0 mmHg, 95% CI 0.01-6.1) was observed in the longest total sleep time quartile group than in the shortest quartile group. These results were similar on sensitivity analyses excluding participants with possible sleep-disordered breathing (n = 69) or nocturnal hypertension (n = 503). CONCLUSION:Decreased sleep quality on actigraphy was significantly associated with higher night-time BP in a large general elderly population. Clinically significant increase in night-time BP exists in relation to decreased objective sleep quality.

journal_name

J Hypertens

journal_title

Journal of hypertension

authors

Oume M,Obayashi K,Asai Y,Ogura M,Takeuchi K,Tai Y,Kurumatani N,Saeki K

doi

10.1097/HJH.0000000000001569

subject

Has Abstract

pub_date

2018-03-01 00:00:00

pages

601-607

issue

3

eissn

0263-6352

issn

1473-5598

journal_volume

36

pub_type

杂志文章
  • Effect of acute hyperglycemia on erythrocyte membrane ion transport in offspring of hypertensive parents.

    abstract:OBJECTIVE:Patients with essential hypertension exhibit several red blood cell (RBC) ion transport abnormalities, insulin resistance (IR) and increased risk of developing type 2 diabetes. The aims of this study were to assess RBC ion transport activities under basal conditions and to test the in vivo effect of acute hyp...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200307000-00021

    authors: Suchánková G,Vlasáková Z,Zicha J,Vokurková M,Dobesová Z,Pelikánová T

    更新日期:2003-07-01 00:00:00

  • Dipyridamole-atropine stress echocardiography versus exercise SPECT scintigraphy for detection of coronary artery disease in hypertensives with positive exercise test.

    abstract:OBJECTIVES:Many different stress echocardiographic and radionuclide perfusion imaging tests have been proposed for detecting epicardial coronary artery disease (CAD) in hypertensive patients. Their relative diagnostic and prognostic value has not been exactly established. BACKGROUND:A positive exercise electrocardiogr...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200103000-00018

    authors: Astarita C,Pálinkás A,Nicolai E,Maresca FS,Varga A,Picano E

    更新日期:2001-03-01 00:00:00

  • Aortic dilatation in Marfan syndrome: role of arterial stiffness and fibrillin-1 variants.

    abstract:OBJECTIVE:Marfan syndrome (MFS) is an autosomal dominant genetic disorder characterized by aortic root dilation and dissection and an abnormal fibrillin-1 synthesis. In this observational study, we evaluated aortic stiffness in MFS and its association with ascending aorta diameters and fibrillin-1 genotype. METHODS:A ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000001512

    authors: Salvi P,Grillo A,Marelli S,Gao L,Salvi L,Viecca M,Di Blasio AM,Carretta R,Pini A,Parati G

    更新日期:2018-01-01 00:00:00

  • The use of single-pill combinations as first-line treatment for hypertension: translating guidelines into clinical practice.

    abstract::: The 2008 European Society of Cardiology/European Society of Hypertension guidelines recommend the first-line prescription of two antihypertensive drugs in single-pill combinations (SPCs), also known as fixed-dose combinations, for the treatment of most patients with hypertension. This recommendation is based on a la...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000002598

    authors: Campana E,Cunha V,Glaveckaite S,Gruev I,Lamirault G,Lehmann E,Masi S,Mfeukeu Kuate L,Mishshenko L,Ona DID,Oo MZ,Tautu OGF,Vachulova A,Vintila AM,Wolf J,Zvartau N,Narkiewicz K,Laurent S

    更新日期:2020-12-01 00:00:00

  • Angiotensin type 1 receptor antagonists induce human in-vitro adipogenesis through peroxisome proliferator-activated receptor-gamma activation.

    abstract:OBJECTIVE:In clonal animal cells, certain angiotensin receptor blockers (ARB) activate the peroxisome proliferator-activated receptor-gamma (PPARgamma). The aim of this work was to validate that observation in human cells and humans. METHODS:We investigated the induction of in-vitro adipogenesis and the activation of ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/01.hjh.0000242405.68461.84

    authors: Janke J,Schupp M,Engeli S,Gorzelniak K,Boschmann M,Sauma L,Nystrom FH,Jordan J,Luft FC,Sharma AM

    更新日期:2006-09-01 00:00:00

  • Orlistat in hypertensive overweight/obese patients: results of a randomized clinical trial.

    abstract:OBJECTIVE:To assess the effect of orlistat plus diet compared with diet alone in promoting weight loss and blood pressure reduction in hypertensive, overweight/obese patients. DESIGN:A pragmatic randomized, controlled trial. SETTING:Hypertension clinic of a university hospital. PATIENTS:Hypertensive patients aged 18...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004872-200311000-00026

    authors: Bloch KV,Salles GF,Muxfeldt ES,Da Rocha Nogueira A

    更新日期:2003-11-01 00:00:00

  • Homozygosity for angiotensinogen 235T variant increases the risk of myocardial infarction in patients with multi-vessel coronary artery disease.

    abstract:OBJECTIVE:Molecular variants of the angiotensinogen (AGT) and the angiotensin II type 1 receptor (ATR) genes have been associated with the risk of coronary artery disease (CAD) and myocardial infarction (MI), but data so far available are conflicting. The primary object of the paper is to verify this possible associati...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200105000-00007

    authors: Olivieri O,Stranieri C,Girelli D,Pizzolo F,Grazioli S,Russo C,Pignatti PF,Corrocher R

    更新日期:2001-05-01 00:00:00

  • Computerized measurement of retinal blood vessel calibre: description, validation and use to determine the influence of ageing and hypertension.

    abstract:OBJECTIVE:To validate a computer-based method for measuring the calibre of retinal blood vessels, and use it to determine the effects of ageing and arterial hypertension on the calibres of these vessels and on their ratio. METHODS:Digital eye fundus images covering a 50 degrees field and centred on the optic disc were...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.hjh.0000163154.35577.8e

    authors: Pose-Reino A,Gomez-Ulla F,Hayik B,Rodriguez-Fernández M,Carreira-Nouche MJ,Mosquera-González A,González-Penedo M,Gude F

    更新日期:2005-04-01 00:00:00

  • Low-dose eplerenone decreases left ventricular mass in treatment-resistant hypertension.

    abstract:BACKGROUND:Mineralocorticoid receptor antagonists are increasingly used in patients with treatment-resistant hypertension (TRH). There is experimental evidence for blood pressure (BP) independent effects of mineralocorticoid receptor blockade on cardiovascular target organ damage. We hypothesized that low-dose eplereno...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/HJH.0000000000001264

    authors: Schneider A,Schwab J,Karg MV,Kalizki T,Reinold A,Schneider MP,Schmieder RE,Schmidt BM

    更新日期:2017-05-01 00:00:00

  • Dissociation between blood pressure reduction and fall in proteinuria in primary renal disease: a randomized double-blind trial.

    abstract:OBJECTIVE:Guidelines recommend lower threshold and goal blood pressure (BP) for patients with proteinuria. BP reduction could be accompanied by a different fall in proteinuria depending of the antihypertensive drug. The objective was to compare proteinuria reduction when BP is lowered to the same level with different d...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00004872-200204000-00032

    authors: PROCOPA Study Group.

    更新日期:2002-04-01 00:00:00

  • Polymorphism of the angiotensin I converting enzyme gene is apparently not related to high blood pressure: Dutch Hypertension and Offspring Study.

    abstract:OBJECTIVE:Studies in genetically hypertensive rats and their normotensive Wistar-Kyoto control rats have revealed a linkage of a chromosomal region containing the angiotensin converting enzyme (ACE) gene with blood pressure. This led to the hypothesis that ACE is a possible candidate gene for primary hypertension in hu...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199304000-00003

    authors: Schmidt S,van Hooft IM,Grobbee DE,Ganten D,Ritz E

    更新日期:1993-04-01 00:00:00

  • Sodium-lithium countertransport: physiology and function.

    abstract::Current opinions on the relationships between erythrocyte sodium-lithium countertransport kinetics and primary hypertension, hyperlipidaemia and diabetic nephropathy are reviewed. Problems associated with the assay are analysed. Some possible mechanisms that could modify the kinetics of ion exchange are examined. The ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1097/00004872-199816010-00002

    authors: West IC,Rutherford PA,Thomas TH

    更新日期:1998-01-01 00:00:00

  • Time trend in hypertension prevalence, awareness, treatment, and control in a contemporary cohort of HIV-infected patients: the HIV and Hypertension Study.

    abstract:BACKGROUND:Hypertension control is often inadequate in HIV patients. In a contemporary, nationwide cohort of Italian HIV-infected adults, we assessed time trends in hypertension prevalence, awareness, treatment, and control. We also evaluated predictors of cardiovascular events and of new-onset hypertension. METHODS:M...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,多中心研究

    doi:10.1097/HJH.0000000000001150

    authors: De Socio GV,Ricci E,Maggi P,Parruti G,Celesia BM,Orofino G,Madeddu G,Martinelli C,Menzaghi B,Taramasso L,Bonfanti P,Pucci G,Schillaci G,CISAI study group.

    更新日期:2017-02-01 00:00:00

  • Regional haemodynamic effects of endothelin-1 in rat and man: unexpected adverse reaction.

    abstract::Endothelin-1 was infused into the non-dominant brachial artery in two male subjects. We then monitored intra-arterial mean blood pressure, right atrial pressure, the heart rate and forearm blood flow (by plethysmography). Endothelin-1 at a dose of 5 x 10(-14) to 5 x 10(-9) mol, infused over 5 min periods, elicited no ...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章

    doi:10.1097/00004872-199009000-00004

    authors: Dahlöf B,Gustafsson D,Hedner T,Jern S,Hansson L

    更新日期:1990-09-01 00:00:00

  • Expression of cardiac angiotensin II AT1 receptor genes in rat hearts is regulated by steroids but not by angiotensin II.

    abstract:OBJECTIVE:To examine the regulation by angiotensin II and by steroids of the expression of the angiotensin II AT1a and AT1b receptor genes in rat hearts. METHODS:Endogenous levels of angiotensin II in the rats were increased either by unilateral 0.2-mm renal artery clips or by subcutaneous infusions of frusemide (12 m...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:

    authors: Della Bruna R,Ries S,Himmelstoss C,Kurtz A

    更新日期:1995-07-01 00:00:00

  • Long-term chronic baroreflex activation: persistent efficacy in patients with heart failure and reduced ejection fraction.

    abstract:AIMS:Baroreflex activation therapy (BAT) has recently been shown to reduce muscle sympathetic nerve activity and hospitalization rate while improving clinical variables through 6 months of therapy in patients with heart failure and reduced ejection fraction (HFrEF). The objective of the present study is to extend the i...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章

    doi:10.1097/HJH.0000000000000603

    authors: Gronda E,Seravalle G,Trevano FQ,Costantino G,Casini A,Alsheraei A,Lovett EG,Vanoli E,Mancia G,Grassi G

    更新日期:2015-08-01 00:00:00

  • Nitric oxide production by human umbilical vessels in severe pre-eclampsia.

    abstract:OBJECTIVE:Pre-eclampsia is characterized by an increased vascular tone which might be related to an abnormal endothelial cell function. As representatives of the fetal circulation, we compared the nitric oxide (NO)-releasing capacity of human umbilical vessels from normal and pre-eclamptic pregnancies. METHODS:Normal ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:

    authors: Akar F,Ark M,Uydeş BS,Soysal ME,Saraçoğlu F,Abacioğlu N,Van de Voorde J,Kanzik I

    更新日期:1994-11-01 00:00:00

  • Polymorphism in the angiotensin converting enzyme but not in the angiotensinogen gene is associated with hypertension and type 2 diabetes: the Skaraborg Hypertension and diabetes project.

    abstract:OBJECTIVE:To study the association between polymorphisms in the angiotensin converting enzyme (ACE) gene and angiotensinogen (AGT) gene and hypertension and/or type 2 diabetes in a community population. PATIENTS AND METHODS:The insertion (I)/deletion (D) polymorphism of the ACE gene and the M235T polymorphism of the A...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199917110-00010

    authors: Bengtsson K,Orho-Melander M,Lindblad U,Melander O,Bøg-Hansen E,Ranstam J,Råstam L,Groop L

    更新日期:1999-11-01 00:00:00

  • Effects of blood pressure lowering on outcome incidence in hypertension: 4. Effects of various classes of antihypertensive drugs--overview and meta-analyses.

    abstract:BACKGROUND AND OBJECTIVES:In 68 randomized controlled trials (RCTs), blood pressure (BP) lowering was obtained by using drugs of different classes. We have investigated whether BP lowering by any of the major drug classes is effective in reducing the cardiovascular outcomes. METHODS:A total of 55 RCTs (19,5 267 indivi...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/HJH.0000000000000447

    authors: Thomopoulos C,Parati G,Zanchetti A

    更新日期:2015-02-01 00:00:00

  • Twenty-four-hour ambulatory blood pressure in adult women with urinary tract infection in childhood.

    abstract:OBJECTIVE:To study 24-h ambulatory blood pressure (BP) and development of hypertension over four decades in women with childhood urinary tract infection (UTI) associated with renal damage. METHODS:A population-based group of 111 women was followed from their first UTI in childhood. The cohort was investigated at a med...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000000234

    authors: Gebäck C,Hansson S,Himmelmann A,Sandberg T,Sixt R,Jodal U

    更新日期:2014-08-01 00:00:00

  • Adrenocorticotropic hormone is produced in the ventricle of patients with essential hypertension.

    abstract:OBJECTIVE:Aldosterone is produced in the ventricle of patients with hypertension. The present study was designed to examine whether adrenocorticotropic hormone (ACTH) and cortisol are also produced from the heart in patients with essential hypertension. METHODS:The study population consisted of 57 patients with essent...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200502000-00024

    authors: Mizuno Y,Yasue H,Yoshimura M,Harada E,Fujii H,Nakamura S,Yamamoto N,Ogawa H,Nakao K

    更新日期:2005-02-01 00:00:00

  • Changes of blood pressure patterns and target organ damage in patients with chronic kidney disease: results of the APrODiTe-2 study.

    abstract:OBJECTIVE:Blood pressure (BP) control is the most established practice for preventing the progression of chronic kidney disease (CKD). We examined the BP control and nocturnal dipping pattern changes in hypertensive patients with CKD and their effects on target organ damages. METHODS:We recruited 378 hypertensive CKD ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000001185

    authors: Cha RH,Lee H,Lee JP,Kang E,Song YR,Kim YS,Kim SG

    更新日期:2017-03-01 00:00:00

  • Alcohol intake and cardiovascular mortality in hypertensive patients: report from the Department of Health Hypertension Care Computing Project.

    abstract:OBJECTIVE:To determine the benefits and risks of drinking alcohol in treated hypertensives. DESIGN:A prospective study of 6,369 hypertensives (3,161 men) attending primarily hospital clinics in the UK. METHODS:Relative risks both for drinkers compared with non-drinkers and for level of alcohol consumption were calcul...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199509000-00004

    authors: Palmer AJ,Fletcher AE,Bulpitt CJ,Beevers DG,Coles EC,Ledingham JG,Petrie JC,Webster J,Dollery CT

    更新日期:1995-09-01 00:00:00

  • Metabolomics in hypertension.

    abstract::Hypertension is the most prevalent chronic medical condition and a major risk factor for cardiovascular morbidity and mortality. In the majority of hypertensive cases, the underlying cause of hypertension cannot be easily identified because of the heterogeneous, polygenic and multi-factorial nature of hypertension. Me...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1097/HJH.0000000000000168

    authors: Nikolic SB,Sharman JE,Adams MJ,Edwards LM

    更新日期:2014-06-01 00:00:00

  • Influence of the renal medulla and early treatment with enalapril upon the development of hypertension in young spontaneously hypertensive rats.

    abstract:OBJECTIVE:To investigate the role of the renal medulla in early hypertension in spontaneously hypertensive rats (SHR), and to explore whether the attenuated increase of pressure induced by enalapril treatment is affected by chemical medullectomy. DESIGN:Forty-four male SHR were studied from 5 to 18 weeks of age: 22 re...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199211000-00006

    authors: Bergström G,Bohman SO,Folkow B,Göthberg G,Rudenstam J,Karlström G

    更新日期:1992-11-01 00:00:00

  • Optimal schedule for home blood pressure monitoring based on a clinical approach.

    abstract:OBJECTIVE:The aim of this study was to determine the optimal schedule for home blood pressure (HBP) measurement based on a clinical approach. METHODS:Four hundred and sixty-four participants underwent HBP measurement for 7 days (duplicate measurements in the morning and in the evening), ambulatory blood pressure (ABP)...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e328332fa5e

    authors: Johansson JK,Niiranen TJ,Puukka PJ,Jula AM

    更新日期:2010-02-01 00:00:00

  • Neonatal sympathectomy of normotensive Wistar-Kyoto and spontaneously hypertensive rats with 6-hydroxydopamine: effects on resistance vessel structure and sensitivity to calcium.

    abstract::6-Hydroxydopamine (6-OHDA) was injected on alternate days from birth to 3 weeks of age into spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) control rats. The effects of this neonatal treatment on cardiovascular structure and mesenteric resistance vessel calcium sensitivity was studied in young (6 ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-198608000-00010

    authors: Nyborg NC,Korsgaard N,Mulvany MJ

    更新日期:1986-08-01 00:00:00

  • Perspectives on hypertension's prevalence, treatment and control in a high cardiovascular risk East European country: data from the SEPHAR III survey.

    abstract:OBJECTIVES:To estimate the trend in arterial hypertension's prevalence, awareness, treatment, and control in Romania, starting from the latest national survey Study for the Evaluation of Prevalence of Hypertension and Cardiovascular Risk in Romania III that has a crucial importance for the development of prevention str...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000001572

    authors: Dorobantu M,Tautu OF,Dimulescu D,Sinescu C,Gusbeth-Tatomir P,Arsenescu-Georgescu C,Mitu F,Lighezan D,Pop C,Babes K,Giuca A,Branza I,Udrescu M,Herdea V,Darabont R

    更新日期:2018-03-01 00:00:00

  • Chronic antioxidant treatment improves sympathetic functions and beta-adrenergic pathway in the spontaneously hypertensive rats.

    abstract:BACKGROUND:Correlations have been found between oxidative stress and hypertension. OBJECTIVE:To determine whether antioxidants can normalize sympathetic dysfunction at pre- or postsynaptic levels in spontaneously hypertensive rats (SHRs). METHODS AND RESULTS:Untreated SHRs and Wistar-Kyoto (WKY) rats were compared wi...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200301000-00028

    authors: Girouard H,Chulak C,LeJossec M,Lamontagne D,de Champlain J

    更新日期:2003-01-01 00:00:00

  • Enhanced sympathoadrenal reactivity to haemorrhagic stress in DOCA-salt hypertensive rats.

    abstract::The effect of haemorrhagic hypotension on plasma catecholamine levels was studied in anesthetized normotensive and DOCA-salt hypertensive rats. The basal levels of plasma norepinephrine (NE) were significantly higher in DOCA-salt hypertensive rats than in normotensive rats. Moreover, the elevations in plasma NE and ep...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-198903000-00011

    authors: Drolet G,Bouvier M,de Champlain J

    更新日期:1989-03-01 00:00:00