Sodium-lithium countertransport: physiology and function.

abstract：OBJECTIVE:We tested the reproducibility of ambulatory blood pressure (ABP), BP variability, and BP reduction in hypertensive patients. METHODS:Forty-two hypertensive patients were enrolled, and ABP monitoring (ABPM) was performed four times in each patient: twice before and twice after the treatment. Morning BP was de...

journal_title：Journal of hypertension

authors： Eguchi K,Hoshide S,Hoshide Y,Ishikawa S,Shimada K,Kario K

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVES:Remodeling of small resistance arteries is an early sign of target organ damage in hypertension. Peripheral capillary morphology abnormalities in hypertension are not well studied. The study objective was to determine whether altered capillary morphology is associated with SBP, DBP, or both in individuals wi...

journal_title：Journal of hypertension

authors： Cheng C,Daskalakis C,Falkner B

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The current standard for arterial stiffness assessment, aortic pulse wave velocity (aPWV), is measured at diastolic pressure. Arterial stiffness, however, is pressure dependent. At the carotid artery level, the degree of this dependency can be quantified as the difference (ΔPWV) between systolic and diastoli...

journal_title：Journal of hypertension

authors： Hermeling E,Vermeersch SJ,Rietzschel ER,de Buyzere ML,Gillebert TC,van de Laar RJ,Ferreira I,Hoeks AP,van Bortel LM,Reneman RS,Segers P,Reesink KD

更新日期：2012-02-01 00:00:00

abstract：:The postulated antihypertensive effect of dietary fish oil and the influence of dietary sodium on this effect were evaluated in young stroke-prone spontaneously hypertensive rats (SHRSP) by direct intra-arterial measurement of blood pressure. Weaning rats were fed synthetic diets containing olive oil or eicosapentaeno...

journal_title：Journal of hypertension

authors： Howe PR,Lungershausen YK,Rogers PF,Gerkens JF,Head RJ,Smith RM

更新日期：1991-07-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to investigate the haemodynamic effects of hormonal changes during the menstrual cycle in 11 hypertensive women aged between 29 and 38 years. DESIGN:In randomized order, the subjects were examined on days 2-7 (follicular phase) and on days 20-24 (luteal phase). All medication was wit...

journal_title：Journal of hypertension

authors： Manhem K,Jern C,Pilhall M,Hansson L,Jern S

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Vascular and lung function develop and decline over the life course; both predict cardiovascular events and mortality but little is known of how they develop over time. We analysed their relationship in a multiethnic cohort study to test whether lung function from early adolescence to young adulthood affecte...

journal_title：Journal of hypertension

authors： Lu Y,Sooky L,Silva MJ,Molaodi OR,Karamanos A,Cruickshank JK,Harding S

更新日期：2017-11-01 00:00:00

abstract：:The activity of renal Na-K-ATPase was compared in hypertension-prone (SBH) and hypertension-resistant (SBN) Sabra rats on regular sodium intake and 2-3 weeks after a high sodium diet. ATPase activity was determined in single nephron segments by a micromethod. The activity profile was found to be similar in the two sub...

journal_title：Journal of hypertension

authors： Doucet A,Mekler J,el Mernissi G,Ben-Ishay D

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVES:The global morbidity and mortality related to hypertension and associated disorders increases continuously and novel therapeutic strategies are still in high demand. Increasing evidence suggests the important role in blood pressure regulation of cytochrome P-450-dependent metabolites of arachidonic acid. Epo...

journal_title：Journal of hypertension

authors： Gawrys O,Husková Z,Baranowska I,Walkowska A,Sadowski J,Kikerlová S,Vaňourková Z,Honetschlägerová Z,Škaroupková P,Červenka L,Falck JR,Imig JD,Kompanowska-Jezierska E

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:Previous studies have demonstrated that the time rate of blood pressure (BP) variation was associated with early carotid atherosclerosis, independent of peripheral and central BP levels. We evaluated the association between the rate of BP variation, derived from ambulatory BP monitoring (ABPM) data analysis,...

journal_title：Journal of hypertension

authors： Manios E,Stamatelopoulos K,Tsivgoulis G,Barlas G,Koroboki E,Tsagalis G,Michas F,Vemmos K,Zakopoulos N

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:Patients with essential hypertension exhibit several red blood cell (RBC) ion transport abnormalities, insulin resistance (IR) and increased risk of developing type 2 diabetes. The aims of this study were to assess RBC ion transport activities under basal conditions and to test the in vivo effect of acute hyp...

journal_title：Journal of hypertension

authors： Suchánková G,Vlasáková Z,Zicha J,Vokurková M,Dobesová Z,Pelikánová T

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:Traditional cardiovascular risk factors do not fully account for ethnic differences in cardiovascular disease. We tested if arterial function indices, particularly augmentation index (AIx), and their determinants from childhood could underlie such ethnic variability among young British adults in the 'DASH' lo...

journal_title：Journal of hypertension

authors： Faconti L,Silva MJ,Molaodi OR,Enayat ZE,Cassidy A,Karamanos A,Nanino E,Read UM,Dall P,Stansfield B,Harding S,Cruickshank KJ

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:Aortic (central) blood pressure (BP) differs from brachial BP and may be a superior predictor of cardiovascular events. However, its measurement is currently restricted to research settings, owing to a moderate level of operator dependency. We tested a new noninvasive device in a large UK cohort. The device ...

journal_title：Journal of hypertension

authors： Park CM,Korolkova O,Davies JE,Parker KH,Siggers JH,March K,Tillin T,Chaturvedi N,Hughes AD

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to define the relationship between physical activity and the magnitude of the percentage fall in blood pressure at night (nocturnal dip). METHODS:We simultaneously monitored 24-h ambulatory blood pressure and measured physical activity by actigraphy in 434 patients. Blood pressure w...

journal_title：Journal of hypertension

authors： Leary AC,Donnan PT,MacDonald TM,Murphy MB

更新日期：2000-04-01 00:00:00

abstract：:Systolic blood pressure was measured on a total of 1855 occasions in 1307 children aged four and five years, and compared with values obtained since birth in the same children. There was a rapid rise in blood pressure in the first month of life. The mean blood pressure then only rose from 93 mmHg at six months to 98 m...

journal_title：Journal of hypertension

authors： de Swiet M,Fayers PM,Shinebourne EA

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVE:To analyze the natriuretic and diuretic response to frusemide in 33 male essential hypertensive patients as a function of basal renal sodium handling and erythrocyte transport system. METHODS:The natriuretic and diuretic response to an oral dose of frusemide (25 mg) was assessed with a simplified method. Uri...

journal_title：Journal of hypertension

authors： Righetti M,Cusi D,Stella P,Rivera R,Bernardi L,del Vecchio L,Bianchi G

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:The renin-angiotensin system plays an important role in blood pressure control. Recently the mouse Ren-2 renin gene was introduced into the genome of rats, producing low-renin hypertensive animals. The aim of the present study was to characterize the pharmacological and morphological properties of mesenteric ...

journal_title：Journal of hypertension

authors： Thybo NK,Korsgaard N,Mulvany MJ

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:Genome-wide association studies have linked variants of fat mass and obesity-associated protein (FTO) to obesity. However, the molecular function of FTO remains unclear. In this study, we sought to investigate the potential effects of FTO in modulating cholesterol deposition in macrophage foam cells, as well ...

journal_title：Journal of hypertension

authors： Mo C,Yang M,Han X,Li J,Gao G,Tai H,Huang N,Xiao H

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:The L/N-type calcium channel blocker (CCB) cilnidipine suppresses sympathetic nerve activity and has a superior renoprotective effect compared with L-type CCBs such as amlodipine. The cardioprotective action of cilnidipine has remained largely uncharacterized, however. We have now investigated the effects of ...

journal_title：Journal of hypertension

authors： Takatsu M,Hattori T,Murase T,Ohtake M,Kato M,Nashima K,Nakashima C,Takahashi K,Ito H,Niinuma K,Aritomi S,Murohara T,Nagata K

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:To compare noninvasive methods to assess pulse wave velocity (PWV) with the invasive gold standard in terms of absolute values, age-related changes, and relationship with subclinical organ damage. METHODS:Invasive aortic PWV (aoPWVinv) was measured in 915 patients undergoing cardiac catheterization (mean ag...

journal_title：Journal of hypertension

authors： Weber T,Wassertheurer S,Hametner B,Parragh S,Eber B

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:To examine in older individuals at high cardiovascular risk whether following a Mediterranean diet decreased the necessity of antihypertensive drugs and modulated their associated cardiovascular risk. METHODS:In the PREvención con DIeta MEDiterránea study, we assessed whether volunteers randomly allocated to...

journal_title：Journal of hypertension

authors： Ribó-Coll M,Lassale C,Sacanella E,Ros E,Toledo E,Sorlí JV,Babio N,Lapetra J,Gómez-Gracia E,Alonso-Gómez ÁM,Fiol M,Serra-Majem L,Pinto X,Castañer O,Díez-Espino J,González JI,Becerra-Tomás N,Cofán M,Díaz-López A,Estru

更新日期：2021-01-25 00:00:00

abstract：:Twenty-four adolescent boys with a positive and 40 boys with a negative parental history of hypertension (PH+ and PH-, respectively) were studied at rest and during exercise on a bicycle ergometer at work loads ranging from 25 to 150 W. Each group was divided into fit and unfit categories on the basis of oxygen consum...

journal_title：Journal of hypertension

authors： Molineux D,Steptoe A

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that sleep-related breathing disorder (SRBD) is associated with increasing severity of cardiovascular risk markers. DESIGN:A cross-sectional study of sleep laboratory patients. SETTING:University Hospital Sleep Disorders Centre. PATIENTS:We studied 591 patients referred for a sleep s...

journal_title：Journal of hypertension

authors： Grote L,Hedner J,Peter JH

更新日期：2001-04-01 00:00:00

abstract：:Calcium blockers may reduce contractility of vascular smooth muscle as well as that of myocardial cells. Therefore, falls in both total peripheral vascular resistance (TPR) and cardiac output (CO) might be responsible for a fall in blood pressure (BP) caused by calcium blockers in essential hypertension. We have studi...

journal_title：Journal of hypertension

authors： Omvik P,Lund-Johansen P,Haugland H

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVE:The acute effects of estrogen on hemodynamic responses were studied with emphasis on the sympathoadrenal system and peripheral circulation. DESIGN:Eleven healthy postmenopausal women recruited from the population-based study BEDA were included in this randomized, double-blind, cross-over, placebo-controlled ...

journal_title：Journal of hypertension

authors： Manhem K,Brandin L,Ghanoum B,Rosengren A,Gustafsson H

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the consistency between a randomly recruited Western European population and the participants of the Framingham Heart Study, with respect to the rates and determinants of progression to hypertension. METHODS:Among the non-hypertensive individuals enrolled in the Flemish Study on Environment, Gene...

journal_title：Journal of hypertension

authors： Zhang H,Thijs L,Kuznetsova T,Fagard RH,Li X,Staessen JA

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:Low insulin sensitivity is closely related to both cardiovascular diseases and diabetes development. Still, correlates of insulin sensitivity have mainly been examined in cross-sectional studies. As far as we are aware, the longitudinal stability of insulin sensitivity in young men is largely unknown. We aime...

journal_title：Journal of hypertension

authors： Skårn SN,Flaa A,Kjeldsen SE,Rostrup M,Brunborg C,Reims HM,Fossum E,Høieggen A,Aksnes TA

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Spontaneously hypertensive rats (SHR) are sensitive to a high salt intake and we investigated the question of whether flow-induced dilation is affected by this type of diet, as flow responses are especially sensitive to small changes in extracellular sodium concentrations. METHODS:We evaluated the effects of...

journal_title：Journal of hypertension

authors： Matrougui K,Lévy BI,Schiavi P,Guez D,Henrion D

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Blood pressure management is a key issue among patients with coronary heart disease (CHD). The present study aimed to identify particular patient groups that may need to be specifically targeted in secondary prevention of CHD. METHODS:EUROASPIRE III is a cross-sectional study conducted in 2006-2007 among pa...

journal_title：Journal of hypertension

authors： Prugger C,Keil U,Wellmann J,de Bacquer D,de Backer G,Ambrosio GB,Reiner Z,Gaita D,Wood D,Kotseva K,Heidrich J,EUROASPIRE III Study Group.

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Although the benefit of hypertension treatment is well established in high-risk patients, there is a paucity of evidence regarding the benefit of treatment in patients with uncomplicated hypertension. METHODS:Hypertensive adult patients were selected from the Korea National Health Insurance Sample Cohort in...

journal_title：Journal of hypertension

authors： Lee CJ,Hwang J,Oh J,Lee SH,Kang SM,Choi D,Kim HC,Park S

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Left atrial (LA) enlargement is an index of adverse cardiovascular events. We sought to investigate any possible correlation between haemodynamic load, neurohumoral factors and LA size in the early stages of essential hypertension. METHODS:We studied 94 consecutive middle-aged subjects, with newly diagnosed ...

journal_title：Journal of hypertension

authors： Tsioufis C,Stougiannos P,Taxiarchou E,Skiadas I,Chatzis D,Thomopoulos C,Lalos S,Stefanadis C,Kallikazaros I

更新日期：2006-05-01 00:00:00