Influence of the renal medulla and early treatment with enalapril upon the development of hypertension in young spontaneously hypertensive rats.

abstract：OBJECTIVE:A number of potential interactions between angiotensin-converting enzyme inhibitors and lithium have been described in the literature. In the present study, we investigated the effects of a low-dose combination treatment with lithium and captopril on survival and stroke prevention in salt-loaded, stroke-prone...

journal_title：Journal of hypertension

authors： Xu J,Scholz A,Rösch N,Blume A,Unger T,Kreutz R,Culman J,Gohlke P

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVES:To assess the predictive role of changes in albuminuria on the loss of renal function under antihypertensive treatment in patients with type 2 diabetes (T2D). METHODS:Clinical records from a total of 12 611 patients with hypertension and T2D, attending 100 antidiabetic centers in Italy, with normal estimate...

journal_title：Journal of hypertension

authors： Viazzi F,Ceriello A,Fioretto P,Giorda C,Guida P,Russo G,Greco E,De Cosmo S,Pontremoli R,AMD-Annals Study Group.

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Contrary to lay beliefs, current perceived stress is not consistently associated with the incidence of high blood pressure (BP) in prospective studies, possibly because of moderating factors. The present prospective study examined this association and explored the potential moderating effects of sex or occup...

journal_title：Journal of hypertension

authors： Wiernik E,Nabi H,Pannier B,Czernichow S,Hanon O,Simon T,Simon JM,Thomas F,Ducolombier C,Danchin N,Limosin F,Consoli SM,Lemogne C

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:As a new category of blood pressure (BP) classification according to the Seventh Report of The Joint National Committee, prehypertension has aroused people's great concern in recent years due to its associations with increased incidence of cardiovascular disease. However, there is little information about th...

journal_title：Journal of hypertension

authors： Dong GH,Wang D,Liu MM,Liu YQ,Zhao Y,Yang M,Meng XJ,Tian S,Meng X,Zhang HY

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:To estimate the compliance rate and associated factors among a population of hypertensive subjects registered in hospitals and primary health care centres. DESIGN:A prospective study carried out on a sample of hypertensive subjects. METHOD:Compliance with treatment by the study sample was measured using the...

journal_title：Journal of hypertension

authors： Khalil SA,Elzubier AG

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVES:To investigate whether glucose or insulin is the cause of increases in oxidative stress and blood pressure in insulin-resistant animals, and to evaluate the effects of alpha-lipoic acid (LA) on the production of the superoxide anion (O2-) in the aorta and blood pressure elevations in various models of diabet...

journal_title：Journal of hypertension

authors： El Midaoui A,de Champlain J

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:Recent studies have shown that the heptapeptide angiotensin-(1-7) [Ang-(1-7)] exerts important vasoactive actions and can act as an endogenous physiological antagonist of angiotensin II (Ang II) within the renin-angiotensin system (RAS). The present study was performed to evaluate the effects, first, of chron...

journal_title：Journal of hypertension

authors： Bürgelová M,Vanourková Z,Thumová M,Dvorák P,Opocenský M,Kramer HJ,Zelízko M,Malý J,Bader M,Cervenka L

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:To investigate gender-dependent difference in the free cytosolic calcium concentration ([Ca2+ ]i ) response to angiotensin II (Ang II) in vascular smooth muscle cells (VSMC) isolated from spontaneously hypertensive rats (SHR). To further evaluate this gender-dependent difference by studying the role of thapsi...

journal_title：Journal of hypertension

authors： Loukotová J,Kunes J,Zicha J

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:The renin-angiotensin system plays an important role in blood pressure control. Recently the mouse Ren-2 renin gene was introduced into the genome of rats, producing low-renin hypertensive animals. The aim of the present study was to characterize the pharmacological and morphological properties of mesenteric ...

journal_title：Journal of hypertension

authors： Thybo NK,Korsgaard N,Mulvany MJ

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:Several studies have suggested that orthostatic hypotension may be an independent predictor of cardiovascular or cerebrovascular risk and all-cause mortality, particularly in a geriatric population. In 1996, a consensus defined orthostatic hypotension as a SBP fall at least 20 mmHg and/or a DBP fall at least ...

journal_title：Journal of hypertension

authors： Angelousi A,Girerd N,Benetos A,Frimat L,Gautier S,Weryha G,Boivin JM

更新日期：2014-08-01 00:00:00

abstract：:Normotensives with hypertensive parents have been reported to exhibit enhanced cardiovascular reactions to mental stress. We have examined the question of why this result was not confirmed in all studies. In addition we have investigated whether appropriate tests can be performed under clinical rather than laboratory ...

journal_title：Journal of hypertension

authors： Neus H,Gödderz W,Otten H,Rüddel H,von Eiff AW

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVES:The genes responsible for obesity are also candidate genes for obesity-related conditions, such as hypertension and type 2 diabetes. A functional polymorphism in the uncoupling protein 2 (UCP2) promoter has been reported to be associated with obesity in Caucasians. To clarify the contribution of this polymor...

journal_title：Journal of hypertension

authors： Ji Q,Ikegami H,Fujisawa T,Kawabata Y,Ono M,Nishino M,Ohishi M,Katsuya T,Rakugi H,Ogihara T

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:We examined the effects of treatment with soluble epoxide hydrolase inhibitor (sEHi) and epoxyeicosatrienoic acids (EETs) analogue (EET-A), given alone or combined, on blood pressure (BP) and ischemia/reperfusion myocardial injury in rats with angiotensin II (ANG II)-dependent hypertension. METHODS:Ren-2 tra...

journal_title：Journal of hypertension

authors： Červenka L,Husková Z,Kopkan L,Kikerlová S,Sedláková L,Vaňourková Z,Alánová P,Kolář F,Hammock BD,Hwang SH,Imig JD,Falck JR,Sadowski J,Kompanowska-Jezierska E,Neckář J

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:To determine adrenocorticotrophin dose-response relationships for increase of blood pressure and metabolic parameters of the Sprague-Dawley rat. METHODS:We injected 120 male Sprague-Dawley rats twice daily subcutaneously for 10 days with 0.5, 1, 5, 50, 100, 200 or 500 microg/kg synthetic adrenocorticotrophin...

journal_title：Journal of hypertension

authors： Turner SW,Wen C,Li M,Fraser TB,Whitworth JA

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVES:The interaction between trophoblasts and maternal endothelium is important for placental vascular modeling. Failure of uterine spiral artery transformation is linked to the etiopathology of preeclampsia. Antihypertensive medications used to control hypertension in early pregnancy can alter placental and circ...

journal_title：Journal of hypertension

authors： Xu B,Charlton F,Makris A,Hennessy A

更新日期：2014-05-01 00:00:00

abstract：:: Hypertension is a growing health concern worldwide. Established hypertension is a causative factor of heart failure, which is characterized by increased vascular resistance and intractable uncontrolled blood pressure. Hypertension and heart failure have multiple causes and complex pathophysiology but cellular immuni...

journal_title：Journal of hypertension

authors： Rai A,Narisawa M,Li P,Piao L,Li Y,Yang G,Cheng XW

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:Blood pressure (BP) measurement in atrial fibrillation (AF) patients is problematic and automated monitors are regarded as inaccurate. The optimal procedure for validating BP monitors in AF is questionable. This study evaluated the accuracy of a novel professional oscillometric upper-arm cuff device (Microli...

journal_title：Journal of hypertension

authors： Stergiou GS,Kyriakoulis KG,Bountzona I,Menti A,Destounis A,Kalogeropoulos P,Kollias A

更新日期：2020-10-16 00:00:00

abstract：OBJECTIVE:Despite the widespread use of multivitamin supplements, little is known regarding their effects on blood pressure (BP) and the development of hypertension. We, therefore, sought to prospectively investigate how multivitamin use was associated with incident hypertension among middle-aged and older women. METH...

journal_title：Journal of hypertension

authors： Rautiainen S,Wang L,Lee IM,Manson JE,Gaziano JM,Buring JE,Sesso HD

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To study blood pressure and antihypertensive drug treatment in subjects with contrasting family histories of hypertension. SUBJECTS AND METHODS:We grouped 520 offspring examined in 1990 (mean +/- SD age 36 +/- 7 years) according to their parents' blood pressure screened in 1963-1964 as offspring of two normo...

journal_title：Journal of hypertension

authors： Mo R,Omvik P,Lund-Johansen P

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the effects of acute hyperhomocysteinemia on distensibility and compliance of large peripheral arteries. Isoprostanes generation and antioxidant vitamins were used to assess the role of oxidative stress. DESIGN:A cross-over, double-blind study on distensibility (DC: diste...

journal_title：Journal of hypertension

authors： Arcaro G,Fava C,Dagradi R,Faccini G,Gaino S,Degan M,Lechi C,Lechi A,Minuz P

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:The heptapeptide angiotensin-(1-7) [Ang-(1-7)] has been identified as a versatile, endogenous inhibitor of the renin-angiotensin system (RAS). As the therapeutic response to exogenous RAS inhibitors, such as AT1 receptor antagonists, is altered by changes in salt intake, we investigated the effect of a low, n...

journal_title：Journal of hypertension

authors： Roks AJ,Nijholt J,van Buiten A,van Gilst WH,de Zeeuw D,Henning RH

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:Caffeine is the most widely used pharmacologically active substance. Aortic elastic properties and arterial wave reflection are important factors for the efficient performance of the cardiovascular system, as well as prognosticators of cardiovascular risk. We investigated the effect of caffeine on aortic elas...

journal_title：Journal of hypertension

authors： Vlachopoulos C,Hirata K,O'Rourke MF

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVES:Aortic (central) blood pressure (BP) differs from brachial BP and may be a superior predictor of cardiovascular events. However, its measurement is currently restricted to research settings, owing to a moderate level of operator dependency. We tested a new noninvasive device in a large UK cohort. The device ...

journal_title：Journal of hypertension

authors： Park CM,Korolkova O,Davies JE,Parker KH,Siggers JH,March K,Tillin T,Chaturvedi N,Hughes AD

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that genetically determined alterations of maternal immune tolerance to a foetal semi-allograft are important for the pathogenesis of hypertensive disorders in pregnancy. DESIGN:A genetic association study was performed to analyse the impact of genetic polymorphisms known to be involve...

journal_title：Journal of hypertension

authors： Pfab T,Chen YP,Slowinski T,Richter CM,Godes M,Arck PC,Halle H,Hocher B

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To determine the degree to which hypertension is a risk factor for macrovascular and microvascular complications in type 2 diabetes. DESIGN:Observational prospective study. SUBJECTS:Newly diagnosed Type 2 diabetic patients recruited into the UK Prospective Diabetes Study (n = 3648; mean age 52 years), 40% o...

journal_title：Journal of hypertension

authors：

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVE:We assessed hypertension prevalence, blood pressure (BP)-lowering treatment and control in obese adults compared with lean/normal-weight individuals in France. METHODS:Multistage stratified random sample of 2075 adults from the French Nutrition and Health Survey (ENNS), a cross-sectional national survey carr...

journal_title：Journal of hypertension

authors： Czernichow S,Castetbon K,Salanave B,Vernay M,Barry Y,Batty GD,Hercberg S,Blacher J

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To study the interaction between the C(-344)T polymorphism and known determinants (age, body mass and dietary sodium) of blood pressure and plasma aldosterone. DESIGN:Cross-sectional and longitudinal (1980-1995) survey of male workers in southern Italy. SETTING:Medical centre of the Olivetti factories. PAR...

journal_title：Journal of hypertension

authors： Russo P,Siani A,Venezia A,Iacone R,Russo O,Barba G,D'Elia L,Cappuccio FP,Strazzullo P

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:Experimental data show that ouabain is a modulator of the sodium-potassium pump, which plays an important role in sodium homeostasis and blood pressure regulation. We investigated the distribution of plasma ouabain in the general population in relation to blood pressure and other determinants of sodium homeos...

journal_title：Journal of hypertension

authors： Wang JG,Staessen JA,Messaggio E,Nawrot T,Fagard R,Hamlyn JM,Bianchi G,Manunta P

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVES:Polymorphisms in microRNA genes are related to the risk of ischemic stroke, but the association between miR-34b/c polymorphisms and the risk of ischemic stroke has not been reported. METHODS:MiR-34b/c rs2187473 and rs4938723 polymorphisms were genotyped by Snapshot assay among 495 controls and 492 ischemic ...

journal_title：Journal of hypertension

authors： Wei G,Liao C,Jian C,Liang L,Liu J,Tang Y,Wei Y

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of hypertension and diabetes mellitus on vascular albumin permeability and hypertrophy in 11-week-old Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR) with and without 3 weeks of streptozotocin-induced diabetes. METHODS:Vascular albumin permeability was measured as...

journal_title：Journal of hypertension

authors： Hulthén UL,Rumble J,Cooper ME,Johnston CI

更新日期：1995-05-01 00:00:00