Metabolomics in hypertension.

abstract：OBJECTIVE:To investigate whether a dietary supplement of vitamin B6 could attenuate the elevation of systolic blood pressure (SBP) in Zucker obese or spontaneously hypertensive rats, or rats ingesting sucrose. METHODS:Zucker obese rats (fa/fa), Sprague-Dawley rats with sucrose-induced elevation of SBP, spontaneously h...

journal_title：Journal of hypertension

authors： Lal KJ,Dakshinamurti K,Thliveris J

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Self-measurement of blood pressure (BP) is increasingly being used for the diagnosis of hypertension and to monitor BP at home. Whenever compared with ambulatory BP measurements, home BP values are frequently higher and less predictive for incident cardiovascular events. We hypothesized that this could be ca...

journal_title：Journal of hypertension

authors： Gazzola K,Honingh M,Truijen J,Zuliani G,Van Den Born BH

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:Obstructive sleep apnea (OSA) and hypertension (HYP) frequently coexist and have additive harmful effects on the cardiovascular system. There is also growing evidence that short sleep duration may contribute independently to poor cardiovascular outcome. The aim of this study was to evaluate the potential infl...

journal_title：Journal of hypertension

authors： Nerbass FB,Pedrosa RP,Genta PR,Drager LF,Lorenzi-Filho G

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:Several studies have suggested that orthostatic hypotension may be an independent predictor of cardiovascular or cerebrovascular risk and all-cause mortality, particularly in a geriatric population. In 1996, a consensus defined orthostatic hypotension as a SBP fall at least 20 mmHg and/or a DBP fall at least ...

journal_title：Journal of hypertension

authors： Angelousi A,Girerd N,Benetos A,Frimat L,Gautier S,Weryha G,Boivin JM

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:We report the prevalence, awareness, treatment, and control of hypertension across four Middle Eastern countries (Iran, Occupied Palestinian Territory, Saudi Arabia, and United Arab Emirates), using a standardized and uniform method. METHODS:The Prospective Urban Rural Epidemiology study enrolled participant...

journal_title：Journal of hypertension

authors： Yusufali AM,Khatib R,Islam S,Alhabib KF,Bahonar A,Swidan HM,Khammash U,Alshamiri MQ,Rangarajan S,Yusuf S

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:The catalytic alpha and smaller beta subunits of the plasma membrane Na,K-ATPase occur in various molecular forms (alpha1, alpha2, alpha3, beta1 and beta2). The alpha isoforms of the enzyme have varying affinities for ouabain and exist in different tissues with particular distribution patterns. OBJECTIVE:To...

journal_title：Journal of hypertension

authors： Mayol V,Dignat-George F,Gerbi A,Martin-Vasallo P,Lesaule G,Sampol J,Maixent JM

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Type 2 diabetes mellitus is associated with an increased risk of hypertension, and cardiovascular and renal disease, and it has been recommended that management of hypertension should be more aggressive in presence than in absence of diabetes mellitus, but the matter is controversial at present. OBJECTIVES:...

journal_title：Journal of hypertension

authors： Thomopoulos C,Parati G,Zanchetti A

更新日期：2017-05-01 00:00:00

abstract：:To determine the role of the parasympathetic system in the development of essential hypertension, the concentrations of acetylcholine (ACh) as a parasympathetic marker and norepinephrine (NE) as a sympathetic marker were measured simultaneously in the heart of spontaneously hypertensive rats (SHR) at 4, 10 and 27 week...

journal_title：Journal of hypertension

authors： Tsuboi H,Ohno O,Ogawa K,Ito T,Hashimoto H,Okumura K,Satake T

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVE:To study 24-h ambulatory blood pressure (BP) and development of hypertension over four decades in women with childhood urinary tract infection (UTI) associated with renal damage. METHODS:A population-based group of 111 women was followed from their first UTI in childhood. The cohort was investigated at a med...

journal_title：Journal of hypertension

authors： Gebäck C,Hansson S,Himmelmann A,Sandberg T,Sixt R,Jodal U

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To compare estimates of mean population salt intake in North and South India derived from spot urine samples versus 24-h urine collections. METHODS:In a cross-sectional survey, participants were sampled from slum, urban and rural communities in North and in South India. Participants provided 24-h urine colle...

journal_title：Journal of hypertension

authors： Petersen KS,Johnson C,Mohan S,Rogers K,Shivashankar R,Thout SR,Gupta P,He FJ,MacGregor GA,Webster J,Santos JA,Krishnan A,Maulik PK,Reddy KS,Gupta R,Prabhakaran D,Neal B

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE AND DESIGN:The early phase of weight loss induced by fasting is associated with diuresis, natriuresis and reduction in blood pressure through unclear mechanisms. Atrial natriuretic peptide (ANP) is a cardiac hormone with potent natriuretic, diuretic and hypotensive effects mediated by 'biologically active' re...

journal_title：Journal of hypertension

authors： Sarzani R,Paci VM,Zingaretti CM,Pierleoni C,Cinti S,Cola G,Rappelli A,Dessì-Fulgheri P

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVES:To test whether the Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene is of functional relevance in humans by altering endothelium-dependent vasodilation. BACKGROUND:The Asp298 variant of the eNOS gene product has been associated with arterial hypertension, coronary artery disease ...

journal_title：Journal of hypertension

authors： Schneider MP,Erdmann J,Delles C,Fleck E,Regitz-Zagrosek V,Schmieder RE

更新日期：2000-12-01 00:00:00

abstract：AIM:To investigate same day repeated measures and diurnal variation of arterial stiffness, cardiac output (CO), stroke volume (SV) and total peripheral resistance (TPR) during the third trimester of normal pregnancy. METHODOLOGY:Pulse wave velocity (PWV) and augmentation index (AIx) were recorded using the Arteriograp...

journal_title：Journal of hypertension

authors： Osman MW,Leone F,Nath M,Khalil A,Webb DR,Robinson TG,Mousa HA

更新日期：2017-12-01 00:00:00

abstract：:We have demonstrated high concentrations of inactive renin in mouse amniotic fluid compared with mouse plasma and other organs. Its molecular weight was similar to that of prorenin from the mouse submaxillary gland (42 000 daltons). The activated renin had a Km value of 1.48 greater than M which is identical to that o...

journal_title：Journal of hypertension

authors： Jacobsen J,Poulsen K

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVE:To study the association of physician's sex with blood pressure, lipid control, and cardiovascular risk factors in treated hypertensive men and women, stratified for the sex of their physician. METHODS:In a cross-sectional survey of hypertensive patients, 264 primary care physicians (PCPs), 187 men and 77 wo...

journal_title：Journal of hypertension

authors： Journath G,Hellénius ML,Manhem K,Kjellgren KI,Nilsson PM,Hyper-Q Study Group, Sweden.

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) may lead to the development of hypertension and therapy with continuous positive airway pressure (CPAP) can promote reduction in blood pressure. OBJECTIVE:The objective of this study is to review systematically the effects of CPAP on blood pressure in patients with OSA. METHOD...

journal_title：Journal of hypertension

authors： Schein AS,Kerkhoff AC,Coronel CC,Plentz RD,Sbruzzi G

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:The current study aimed to investigate the value of the computed tomography-based left-versus-right adrenal gland volume ratio (L/Rv) in screening patients with unilateral primary aldosteronism. METHODS:The current study recruited 114 patients who underwent successful adrenal venous sampling (AVS) and adren...

journal_title：Journal of hypertension

authors： Li S,Sun H,Ma L,Zhu Y,Xie W,Sun J,Zhao L,Qing B,Ren Y,Tian H,Chen T

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:Female sexual dysfunction (FSD) is increasingly attracting more scientific and public interest, and represents a poorly investigated issue in patients with essential hypertension. We evaluated the prevalence of sexual dysfunction in hypertensive women compared with normotensive women according to age, hypert...

journal_title：Journal of hypertension

authors： Doumas M,Tsiodras S,Tsakiris A,Douma S,Chounta A,Papadopoulos A,Kanellakopoulou K,Giamarellou H

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To assess the effect of orlistat plus diet compared with diet alone in promoting weight loss and blood pressure reduction in hypertensive, overweight/obese patients. DESIGN:A pragmatic randomized, controlled trial. SETTING:Hypertension clinic of a university hospital. PATIENTS:Hypertensive patients aged 18...

journal_title：Journal of hypertension

authors： Bloch KV,Salles GF,Muxfeldt ES,Da Rocha Nogueira A

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:Caffeine is the most widely used pharmacologically active substance. Aortic elastic properties and arterial wave reflection are important factors for the efficient performance of the cardiovascular system, as well as prognosticators of cardiovascular risk. We investigated the effect of caffeine on aortic elas...

journal_title：Journal of hypertension

authors： Vlachopoulos C,Hirata K,O'Rourke MF

更新日期：2003-03-01 00:00:00

abstract：AIMS:Myocardial fibrosis is a relevant component of hypertensive heart disease (HHD). Novel cardiovascular magnetic resonance (CMR) imaging techniques have shown potential in quantification of diffuse cardiac fibrosis, with T1 mapping, and estimating preclinical cardiac dysfunction, with strain analysis. Molecular biom...

journal_title：Journal of hypertension

authors： Pichler G,Redon J,Martínez F,Solaz E,Calaforra O,Andrés MS,Lopez B,Díez J,Oberbauer R,Adlbrecht C,Karth GD,Maceira A

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:We hypothesized that the aldosterone: renin ratio (ARR) predicts the antihypertensive response to mineralocorticoid receptor antagonist, spironolactone (SPIRO), when compared with bendroflumethiazide (BFZ). METHODS:We conducted a randomized, crossover, trial on hypertensive patients with either high ARR (HA...

journal_title：Journal of hypertension

authors： Parthasarathy HK,Alhashmi K,McMahon AD,Struthers AD,McInnes GT,Ford I,Connell JM,MacDonald TM

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:It has been postulated that hypertension in the spontaneously hypertensive rat (SHR) results from autoimmune damage to the SHR vasculature. The objective of this study was to isolate autoreactive T-cells specific for arterial antigens, and to characterize these cells. DESIGN:The presence of autoreactive T-ce...

journal_title：Journal of hypertension

authors： Ofosu-Appiah W,Ruggiero C,Huang LY

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:High blood pressure is common in acute stroke and is associated independently with poor outcome. Lowering blood pressure might improve outcome, provided it does not reduce cerebral blood flow in the presence of dysfunctional cerebral autoregulation. METHODS:We performed a systematic review of clinical contro...

journal_title：Journal of hypertension

authors： Sare GM,Gray LJ,Bath PM

更新日期：2008-06-01 00:00:00

abstract：:Hypertension is a leading risk factor for mortality. Detecting, treating and monitoring hypertensive patients require accurate blood pressure measurements. Protocols for validation of automatic sphygmomanometers exist, but quality control of validations is limited to peer review of published reports, which has severe ...

journal_title：Journal of hypertension

authors： Turner MJ

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:Blood pressure changes during menopausal transition have not been studied previously using a biracial sample. We investigated whether menopausal transition was associated with change in blood pressure in African-American or white women. DESIGN, SETTING AND PARTICIPANTS:The prospective multicenter study, the ...

journal_title：Journal of hypertension

authors： Luoto R,Sharrett AR,Schreiner P,Sorlie PD,Arnett D,Ephross S

更新日期：2000-01-01 00:00:00

abstract：:To assess the role of renal prostaglandin E in the hypotensive mechanism of MK-421, we evaluated the effects of chronic infusion of MK-421 (6 mg/kg/day i.p.) on systolic blood pressure and urinary prostaglandin E excretion in conscious rats in states of sodium repletion or depletion and also during chronic infusion of...

journal_title：Journal of hypertension

authors： Yasujima M,Abe K,Tanno M,Kasai Y,Sato K,Tajima J,Kudo K,Tsunoda K,Yoshinaga K

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVE:Angiotensin (Ang) II increases reactive oxygen species (ROS), decreases nitric oxide (NO) bioavailability and promotes cardiovascular remodeling. ROS have been identified as critical second messengers of the trophic responses by Ang II. In rats with Ang II-induced hypertension, we investigated the role of ROS...

journal_title：Journal of hypertension

authors： Zhou MS,Jaimes EA,Raij L

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:The usefulness of the hypertensive retinopathy classification by Keith-Wagener-Barker (KWB) in clinical practice remains controversial. The simplified Mitchell-Wong grading, combining the two initial KWB' grades in one stage, is proposed as an alternative method; both systems are poorly validated regarding t...

journal_title：Journal of hypertension

authors： Aissopou EK,Papathanassiou M,Nasothimiou EG,Konstantonis GD,Tentolouris N,Theodossiadis PG,Papaioannou TG,Sfikakis PP,Protogerou AD

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVES:To assess the impact of various criteria used to define hypertension in community surveys on estimates of prevalence, treatment and control. In particular, this paper examines the effect of using mean versus minimum values; one, two or three examinations; and three different blood pressure levels. DESIGN:A ...

journal_title：Journal of hypertension

authors： Birkett NJ

更新日期：1997-03-01 00:00:00