The measurement of central noradrenergic activity in spontaneously hypertensive rats: a comparison of free 3,4-dihydroxyphenylethyleneglycol levels with FLA-63 induced noradrenaline depletion.

abstract：OBJECTIVE:To assess the Accutracker II (version 30/23) ambulatory blood pressure monitor by nationally agreed protocols in order to resolve previous conflicting assessments, and to examine the feasibility of combining these protocols into one study. DESIGN:The protocols of the Association for the Advancement of Medica...

journal_title：Journal of hypertension

authors： Taylor R,Chidley K,Goodwin J,Broeders M,Kirby B

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:Based on results of in vitro studies, it has been hypothesized that blockade of the renin-angiotensin system (RAS) promotes the recruitment and differentiation of pre-adipocytes and that increased formation of small insulin-sensitive adipocytes counteracts ectopic deposition of lipids, thereby improving insul...

journal_title：Journal of hypertension

authors： Furuhashi M,Ura N,Takizawa H,Yoshida D,Moniwa N,Murakami H,Higashiura K,Shimamoto K

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:To examine the changes in plasma brain natriuretic peptide (BNP), atrial natriuretic peptide (ANP) and blood pressure in patients with essential hypertension on a low, normal and high sodium intake. DESIGN AND METHODS:Twelve patients with mild-to-moderate essential hypertension were studied. Plasma, urinary ...

journal_title：Journal of hypertension

authors： Buckley MG,Markandu ND,Sagnella GA,MacGregor GA

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Postmenopausal estrogen replacement, with or without progestins, has been related to lower cardiovascular risks. OBJECTIVE:We investigated whether the actions of estrogen on vascular resistance contribute to this cardioprotective effect. DESIGN AND METHODS:In a 6-month double-blind study, pre- and post-tre...

journal_title：Journal of hypertension

authors： Light KC,Hinderliter AL,West SG,Grewen KM,Steege JF,Sherwood A,Girdler SS

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVES:Current evidence demonstrates that both genetic and environmental factors influence blood pressure. The sympathetic nervous system is a key player in blood pressure control and functional genetic variants of the beta-2 adrenergic receptor (B2AR) have been identified and implicated in the pathogenesis of hype...

journal_title：Journal of hypertension

authors： Binder A,Garcia E,Wallace C,Gbenga K,Ben-Shlomo Y,Yarnell J,Brown P,Caulfield M,Skrabal F,Kotanko P,Munroe P

更新日期：2006-03-01 00:00:00

abstract：:Normotensives with hypertensive parents have been reported to exhibit enhanced cardiovascular reactions to mental stress. We have examined the question of why this result was not confirmed in all studies. In addition we have investigated whether appropriate tests can be performed under clinical rather than laboratory ...

journal_title：Journal of hypertension

authors： Neus H,Gödderz W,Otten H,Rüddel H,von Eiff AW

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVE:To assess the antihypertensive efficacy and safety of the novel AT1 receptor antagonist, telmisartan, compared with that of enalapril in elderly patients with mild to moderate hypertension. DESIGN:A 26-week, multicenter, double-blind, parallel-group, dosage titration study. METHODS:A total of 278 patients a...

journal_title：Journal of hypertension

authors： Karlberg BE,Lins LE,Hermansson K

更新日期：1999-02-01 00:00:00

abstract：:The present study was designed to investigate in rats the influence of converting enzyme inhibition with captopril on blood pressure, plasma urea, plasma renin concentration (PRC), plasma aldosterone and plasma vasopressin, and to define the interrelationships between PRC and these variables during equal degrees of ei...

journal_title：Journal of hypertension

authors： Gardes J,Gonzalez MF,Corvol P,Ménard J

更新日期：1986-04-01 00:00:00

abstract：OBJECTIVE:Caffeine is the most widely used pharmacologically active substance. Aortic elastic properties and arterial wave reflection are important factors for the efficient performance of the cardiovascular system, as well as prognosticators of cardiovascular risk. We investigated the effect of caffeine on aortic elas...

journal_title：Journal of hypertension

authors： Vlachopoulos C,Hirata K,O'Rourke MF

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To evaluate autonomic nervous function by power-spectral analysis of heart-rate variability in salt-sensitive and non-salt-sensitive patients with essential hypertension under the conditions of low and high salt intakes. DESIGN AND METHODS:The blood pressures, heart rates, and electrocardiogram R-R intervals...

journal_title：Journal of hypertension

authors： Minami J,Kawano Y,Ishimitsu T,Takishita S

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVE:The objective of the present study was to assess the regression of left ventricular hypertrophy (LVH) during antihypertensive treatment, and its relationship with the changes in microalbuminuria. INDIVIDUALS AND METHODS:One hundred and sixty-eight previously untreated patients with echocardiographic LVH, 46 ...

journal_title：Journal of hypertension

authors： Rodilla E,Pascual JM,Costa JA,Martin J,Gonzalez C,Redon J

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:We demonstrated in a previous cross-sectional study that arterial compliance is elevated in postmenopausal women taking estrogen-containing hormonal therapy, which may partially account for the reduction in cardiovascular risk observed. OBJECTIVE:To investigate the effects of withdrawal and recommencement o...

journal_title：Journal of hypertension

authors： Waddell TK,Rajkumar C,Cameron JD,Jennings GL,Dart AM,Kingwell BA

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Nitric oxide is involved in the regulation of vascular basal tone and blood pressure. Polymorphisms of NOS3, the gene that codes for endothelial nitric oxide synthase, have been associated with essential hypertension. OBJECTIVE:To look for linkage and association of three di-allelic polymorphisms (Glu298Asp...

journal_title：Journal of hypertension

authors： Persu A,Vinck WJ,El Khattabi O,Janssen RG,Paulussen AD,Devuyst O,Vlietinck R,Fagard RH

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The screening for primary aldosteronism is based on the aldosterone-renin ratio calculated with the plasma renin activity (PRA) value as denominator. A direct measurement of active renin (DRA) is being used as an alternative to PRA, but its diagnostic performance remains unclear. METHOD:We, therefore compar...

journal_title：Journal of hypertension

authors： Rossi GP,Barisa M,Belfiore A,Desideri G,Ferri C,Letizia C,Maccario M,Morganti A,Palumbo G,Patalano A,Roman E,Seccia TM,Pessina AC,Mantero F,PAPY study Investigators.

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Different radiologists may show considerable variation in their interpretation of renal angiograms. We therefore wished to establish the reliability of their interpretation. DESIGN:Assessment of the intra- and inter-observer agreement of the interpretation of renal angiograms. SETTING:Tertiary referral univ...

journal_title：Journal of hypertension

authors： Schreij G,de Haan MW,Oei TK,Koster D,de Leeuw PW

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:The Fas-Fas ligand (FasL) system is involved in apoptosis in many types of cells. Recently, the expression of FasL on endothelial cells was reported. FasL is cleaved by a metalloproteinase and released in serum as soluble FasL (sFasL). Vasoactive substances, including metalloproteinase, are modulated by endo...

journal_title：Journal of hypertension

authors： Okura T,Watanabe S,Jiang Y,Nakamura M,Takata Y,Yang ZH,Kohara K,Kitami Y,Hiwada K

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:The urinary isoflavonoid equol inhibits membrane Na-K-Cl cotransporters at similar concentrations to those at which furosemide inhibits them, but the significance of this action is not known. OBJECTIVE:To investigate the potential salidiuretic and vascular actions of equol in the rat. METHODS:Renal functio...

journal_title：Journal of hypertension

authors： Gimenez I,Lou M,Vargas F,Alvarez-Guerra M,Mayoral JA,Martinez RM,Garay RP,Alda JO

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:To characterize the in vivo vascular properties of the spontaneously hypertensive rat (SHR) renal vascular bed by examining vascular conductance/resistance responsiveness to vasoactive agents in vivo and determining whether the filtration surface area of glomerular capillaries is reduced. DESIGN AND METHODS:...

journal_title：Journal of hypertension

authors： Kett MM,Bergström G,Alcorn D,Bertram JF,Anderson WP

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:Hypertension affects cerebrovascular autoregulation and increases the risk of cerebrovascular events and dementia. Notably, it is associated with cerebrovascular remodeling and lower resting cerebral blood flow (CBF). We wanted to determine, using arterial spin-labeling-MRI, the impact of a head-down tilt (HD...

journal_title：Journal of hypertension

authors： Seiller I,Pavilla A,Ognard J,Ozier-Lafontaine N,Colombani S,Cepeda Ibarra Y,Mejdoubi M

更新日期：2020-12-09 00:00:00

abstract：:The activity of renal Na-K-ATPase was compared in hypertension-prone (SBH) and hypertension-resistant (SBN) Sabra rats on regular sodium intake and 2-3 weeks after a high sodium diet. ATPase activity was determined in single nephron segments by a micromethod. The activity profile was found to be similar in the two sub...

journal_title：Journal of hypertension

authors： Doucet A,Mekler J,el Mernissi G,Ben-Ishay D

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVE:Hypertension is a major risk factor for cardiovascular disease. Polymorphism in the beta2-adrenergic receptor (ADRB2) and nitric oxide synthase 3 (NOS3) genes is associated with clinical cardiovascular phenotypes. The Arg16Gly and Glu298Asp polymorphisms of ADRB2 and NOS3 genes, respectively, have been report...

journal_title：Journal of hypertension

authors： Misono M,Maeda S,Iemitsu M,Nakata Y,Otsuki T,Sugawara J,Zempo H,Yoshizawa M,Miyaki A,Kuno S,Matsuda M,Ajisaka R

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:Recent studies have demonstrated that stimulating autoantibodies against the angiotensin II type 1 receptor (AT1R-AA) are frequently detected in the sera from women with preeclampsia, suggesting that they may play an important role in the pathogenesis of this disease. Nevertheless, the real clinical significa...

journal_title：Journal of hypertension

authors： Leaños-Miranda A,Campos-Galicia I,Alvarez-Jiménez G,Isordia-Salas I,Rivera-Leaños R,Ulloa-Aguirre A

更新日期：2010-04-01 00:00:00

abstract：:Pinacidil is a new vasodilating compound claimed to increase renal perfusion and function. A preliminary study showed that pinacidil did not sustain renal perfusion through a period of increasing renal vascular resistance in pig-to-rabbit renal xenotransplantation. Accordingly, the effect of pinacidil on renal functio...

journal_title：Journal of hypertension

authors： Dieperink H,Kemp E,Jørgensen KA,Starklint H

更新日期：1983-12-01 00:00:00

abstract：OBJECTIVE:Spontaneously hypertensive rats (SHR) are sensitive to a high salt intake and we investigated the question of whether flow-induced dilation is affected by this type of diet, as flow responses are especially sensitive to small changes in extracellular sodium concentrations. METHODS:We evaluated the effects of...

journal_title：Journal of hypertension

authors： Matrougui K,Lévy BI,Schiavi P,Guez D,Henrion D

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:Underlying pathophysiology of orthostatic hypotension has been poorly understood. We hypothesized that aortic pulse pressure (APP) reflecting aortic stiffness may be involved in the development of orthostatic hypotension. METHODS:A total of 200 patients (age 64.3 ± 10.9 years, 62.5% men) who underwent invasi...

journal_title：Journal of hypertension

authors： Chung J,Kim HL,Lim WH,Seo JB,Kim SH,Zo JH,Kim MA

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In the past, different methods have been used to measure the carotid-femoral distance for the assessment of pulse wave velocity (PWV). However, the latest consensus published advises to use 80% of the direct straight carotid-femoral distance (D(0.8)) using either a flexible tape or a sliding c...

journal_title：Journal of hypertension

authors： Levi-Marpillat N,Desamericq G,Akakpo S,Affes-Ayadi H,Tropeano AI,Millasseau S,Macquin-Mavier I

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) may lead to the development of hypertension and therapy with continuous positive airway pressure (CPAP) can promote reduction in blood pressure. OBJECTIVE:The objective of this study is to review systematically the effects of CPAP on blood pressure in patients with OSA. METHOD...

journal_title：Journal of hypertension

authors： Schein AS,Kerkhoff AC,Coronel CC,Plentz RD,Sbruzzi G

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Hypertension is a complex trait with an ill-defined genetic predisposition, in which adrenergic mechanisms seem to be involved even at the early stages. Chromogranin A is a pro-hormone stored and released with catecholamines by exocytosis; its fragment catestatin, formed in vivo, inhibits further catecholami...

journal_title：Journal of hypertension

authors： O'Connor DT,Kailasam MT,Kennedy BP,Ziegler MG,Yanaihara N,Parmer RJ

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVES:To assess the impact of various criteria used to define hypertension in community surveys on estimates of prevalence, treatment and control. In particular, this paper examines the effect of using mean versus minimum values; one, two or three examinations; and three different blood pressure levels. DESIGN:A ...

journal_title：Journal of hypertension

authors： Birkett NJ

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:Few data are available comparing the effects of monotherapy and combination therapy on target organ damage. The PICXEL study compared the efficacy of a strategy based on first-line combination with perindopril/indapamide versus monotherapy with enalapril in reducing left ventricular hypertrophy (LVH) in hyper...

journal_title：Journal of hypertension

authors： Dahlöf B,Gosse P,Guéret P,Dubourg O,de Simone G,Schmieder R,Karpov Y,García-Puig J,Matos L,De Leeuw PW,Degaute JP,Magometschnigg D,PICXEL Investigators.

更新日期：2005-11-01 00:00:00