Genetics of primary aldosteronism.

Abstract:

:Over the last few years, much progress has been made in understanding the genetic basis of primary aldosteronism. This has led to the diagnosis of the familial forms and has aided the understanding of the basis of sporadic forms of the disease. Such information can be exploited to improve the therapeutic approaches used not only for patients with primary aldosteronism, but also with other forms of hypertension. Here, we review the genetic and the phenotypic features of the familial forms, the genetic variants that influence the sporadic forms and the structure and regulation of the CYP11B1 and CYP11B2 genes.

journal_name

J Hypertens

journal_title

Journal of hypertension

authors

Mulatero P,Morello F,Veglio F

doi

10.1097/00004872-200404000-00001

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

663-70

issue

4

eissn

0263-6352

issn

1473-5598

pii

00004872-200404000-00001

journal_volume

22

pub_type

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