Simultaneous radioimmunoassay of six angiotensin peptides in arterial and venous plasma of man.

abstract：OBJECTIVES:To assess the expression of early cardiac genes, implicated in the hypertrophic growth response of the adult heart, in peripheral blood mononuclear cells in patients with essential hypertension and its relationship to ambulatory blood pressure monitoring (ABPM) parameters and to echocardiographic left ventri...

journal_title：Journal of hypertension

authors： Kontaraki JE,Marketou ME,Zacharis EA,Parthenakis FI,Vardas PE

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Neuropeptide W (NPW), an endogenous ligand for the G protein-coupled receptor 7 (GPR7), was first found to make important roles in central nerve system. In periphery, NPW was also present and regulated intracellular calcium homeostasis by L-type calcium channels. This study was designed to discover the effect...

journal_title：Journal of hypertension

authors： Ji L,Zhu H,Chen H,Fan W,Chen J,Chen J,Zhu G,Wang J

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVES:This controlled trial assessed the effect of continuous positive airway pressure (CPAP) on blood pressure (BP) in patients with obstructive sleep apnea (OSA) and resistant hypertension (RH). METHODS:We evaluated 96 patients with resistant hypertension, defined as clinic BP at least 140/90 mmHg despite treat...

journal_title：Journal of hypertension

authors： Lozano L,Tovar JL,Sampol G,Romero O,Jurado MJ,Segarra A,Espinel E,Ríos J,Untoria MD,Lloberes P

更新日期：2010-10-01 00:00:00

abstract：AIM:To investigate same day repeated measures and diurnal variation of arterial stiffness, cardiac output (CO), stroke volume (SV) and total peripheral resistance (TPR) during the third trimester of normal pregnancy. METHODOLOGY:Pulse wave velocity (PWV) and augmentation index (AIx) were recorded using the Arteriograp...

journal_title：Journal of hypertension

authors： Osman MW,Leone F,Nath M,Khalil A,Webb DR,Robinson TG,Mousa HA

更新日期：2017-12-01 00:00:00

abstract：:The associations of obesity and alcohol consumption with blood pressure and the prevalence of hypertension were studied in 5550 male and female subjects aged 25 to 64 years, surveyed in the National Heart Foundation of Australia 1980 Risk Factor Prevalence Study. Body mass index was significantly and independently ass...

journal_title：Journal of hypertension

authors： MacMahon SW,Blacket RB,Macdonald GJ,Hall W

更新日期：1984-02-01 00:00:00

abstract：OBJECTIVE:To determine plasma aldosterone concentration (PAC) and plasma renin concentration (PRC) and aldosterone-to-renin ratio (ARR) values in a population attending a Clinic for Cardiovascular Risk Assessment in Children. METHODS:We assessed ARR and associated factors in a cohort of 287 children (137 female, 4-18 ...

journal_title：Journal of hypertension

authors： Genovesi S,Antolini L,Orlando A,Tassistro E,Giussani M,Nava E,Turolo L,Manolopoulou J,Parati G,Morganti A

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of cyclosporine A (CsA; Sandimmun Neoral) on systemic and renal hemodynamics, tubular function, and sodium excretion in healthy volunteers. Furthermore, we studied whether CsA enhances the systemic and renal hemodynamic sensitivity to norepinephrine. METHODS:Eighteen healthy volunte...

journal_title：Journal of hypertension

authors： Hansen JM,Fogh-Andersen N,Christensen NJ,Strandgaard S

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Although the benefit of hypertension treatment is well established in high-risk patients, there is a paucity of evidence regarding the benefit of treatment in patients with uncomplicated hypertension. METHODS:Hypertensive adult patients were selected from the Korea National Health Insurance Sample Cohort in...

journal_title：Journal of hypertension

authors： Lee CJ,Hwang J,Oh J,Lee SH,Kang SM,Choi D,Kim HC,Park S

更新日期：2017-05-01 00:00:00

abstract：:The present study investigated the roles of insulin on central cardiovascular regulation. When rats were fed with a high-salt diet for 4 weeks, hypothalamic and pituitary contents of insulin-like immunoreactive substance (ILI) significantly decreased. The plasma concentration of ILI remained unaltered, however. Intrac...

journal_title：Journal of hypertension

authors： Nishimura M,Takahashi H,Matsusawa M,Ikegaki I,Nakanishi T,Yoshimura M

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Results from previous studies suggested that a blunted response of renal plasma flow (RPF) to angiotensin II infusion during a high-sodium diet (a phenotype associated with nonmodulation) is an intermediate phenotype for essential hypertension. OBJECTIVE:To determine whether RPF traits used to investigate n...

journal_title：Journal of hypertension

authors： Kardia SL,Sing CF,Turner ST

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:Recent studies have demonstrated that stimulating autoantibodies against the angiotensin II type 1 receptor (AT1R-AA) are frequently detected in the sera from women with preeclampsia, suggesting that they may play an important role in the pathogenesis of this disease. Nevertheless, the real clinical significa...

journal_title：Journal of hypertension

authors： Leaños-Miranda A,Campos-Galicia I,Alvarez-Jiménez G,Isordia-Salas I,Rivera-Leaños R,Ulloa-Aguirre A

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVES AND DESIGN:Angiotensinogen (AGT) gene variants influence angiotensinogen plasma levels in children and young adults. The angiotensinogen promoter (-6)A variant facilitates gene transcription in human tissues and it has been associated with high blood pressure in older adults. A young adult population can be ...

journal_title：Journal of hypertension

authors： Sarzani R,Dessì-Fulgheri P,Mazzara D,Catalini R,Cola G,Bersigotti G,Siragusa N,Salvi F,Ercolani P,Spagnolo D,Zingaretti O,Serenelli M,Pupita M,Magni CM,Giantomassi L,Pasquini R,Gesuita R,Carle F,Rappelli A

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:To determine whether 'slow pressor' hypertension from systemic angiotensin (Ang II) infusion was associated with renal vascular structural remodeling of the renal resistance vessels and glomerulus. METHODS:Ang II (4.5-10 ng/kg per min) or vehicle was infused for 10 days. Renal resistance vascular lumen chan...

journal_title：Journal of hypertension

authors： Edgley AJ,Kett MM,Anderson WP

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:Metabolic syndrome (MetS) is associated with uncontrolled blood pressure (BP), despite use of aggressive therapy. This study was performed to assess whether the use of different classes of antihypertensive drugs might influence this association. METHODS:We evaluated risk of uncontrolled BP (BP ≥ 140/90 mmHg ...

journal_title：Journal of hypertension

authors： De Marco M,de Simone G,Izzo R,Mancusi C,Sforza A,Giudice R,Trimarco B,De Luca N

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To conduct a longitudinal evaluation of the central haemodynamic adaptations of normal pregnancy. METHODS:This was a prospective longitudinal study involving healthy, normotensive women who were having an uncomplicated, singleton pregnancy. Brachial and central SBP, DBP, mean arterial pressure (MAP), brachia...

journal_title：Journal of hypertension

authors： O' Callaghan KM,Hennessy Á,Malvisi L,Kiely M

更新日期：2018-10-01 00:00:00

abstract：:The cardiovascular responses to selective alpha 1- and alpha 2-adrenoceptor antagonism (with prazosin and idazoxan, respectively) were assessed in rats 4 weeks after unilateral nephro-adrenalectomy, contralateral adrenal enucleation and the provision of a 1% NaCl solution as drinking fluid (AEN rats) and in sham-opera...

journal_title：Journal of hypertension

authors： Foulkes R,Gardiner SM,Bennett T

更新日期：1988-04-01 00:00:00

abstract：:The effect of haemorrhagic hypotension on plasma catecholamine levels was studied in anesthetized normotensive and DOCA-salt hypertensive rats. The basal levels of plasma norepinephrine (NE) were significantly higher in DOCA-salt hypertensive rats than in normotensive rats. Moreover, the elevations in plasma NE and ep...

journal_title：Journal of hypertension

authors： Drolet G,Bouvier M,de Champlain J

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Secondary prevention of stroke with antihypertensive drugs is now standard practice, but it is unclear how soon after a cerebrovascular event antihypertensive therapy should be initiated or re-started. Due to impaired cerebral autoregulation, changes in systemic blood pressure may be reflected in cerebral pe...

journal_title：Journal of hypertension

authors： Nazir FS,Overell JR,Bolster A,Hilditch TE,Reid JL,Lees KR

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To investigate predictors of left ventricular mass corrected for height2.7 (LVMI) and left ventricular hypertrophy in patients who were found to be normotensive with both office and 24-h ambulatory blood pressure (BP) measurements. METHODS:A total of 805 consecutive patients were analyzed. All patients under...

journal_title：Journal of hypertension

authors： Kotsis V,Stabouli S,Toumanidis S,Tsivgoulis G,Rizos Z,Trakateli C,Zakopoulos N,Sion M

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Arterial stiffness is an independent cardiovascular risk factor. Aging, high blood pressure and increased renin-angiotensin system activity contribute to increased arterial stiffness in patients with atherosclerotic renovascular hypertension (aRVH). A literature search failed to identify any study related to ...

journal_title：Journal of hypertension

authors： Fodor L,Premužić V,Ivković V,Perkov D,Laganović M,Vrkić TZ,Dika Z,Zivko M,Jelaković B

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that sleep-related breathing disorder (SRBD) is associated with increasing severity of cardiovascular risk markers. DESIGN:A cross-sectional study of sleep laboratory patients. SETTING:University Hospital Sleep Disorders Centre. PATIENTS:We studied 591 patients referred for a sleep s...

journal_title：Journal of hypertension

authors： Grote L,Hedner J,Peter JH

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVES:The current study aimed to investigate the value of the computed tomography-based left-versus-right adrenal gland volume ratio (L/Rv) in screening patients with unilateral primary aldosteronism. METHODS:The current study recruited 114 patients who underwent successful adrenal venous sampling (AVS) and adren...

journal_title：Journal of hypertension

authors： Li S,Sun H,Ma L,Zhu Y,Xie W,Sun J,Zhao L,Qing B,Ren Y,Tian H,Chen T

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:To assess the Accutracker II (version 30/23) ambulatory blood pressure monitor by nationally agreed protocols in order to resolve previous conflicting assessments, and to examine the feasibility of combining these protocols into one study. DESIGN:The protocols of the Association for the Advancement of Medica...

journal_title：Journal of hypertension

authors： Taylor R,Chidley K,Goodwin J,Broeders M,Kirby B

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVES:(1) To compare urinary guanosine 3',5' cyclic monophosphate (cyclic GMP) excretion between normotensive subjects and essential hypertensive patients; (2) to determine the influence of changes in sodium intake on urinary cyclic GMP excretion in response to the neutral endopeptidase inhibitor candoxatril in es...

journal_title：Journal of hypertension

authors： Sagnella GA,Singer DR,Markandu ND,Buckley MG,MacGregor GA

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:Previous studies on multicellular preparations have shown that hypertrophied cardiac muscle from the spontaneously hypertensive rat (SHR) has a prolonged action potential. The first aim of the present study was to determine whether the action potential of isolated left ventricular myocytes was similarly prolo...

journal_title：Journal of hypertension

authors： Brooksby P,Levi AJ,Jones JV

更新日期：1993-06-01 00:00:00

abstract：OBJECTIVES:We hypothesized that addressing the 24-h relationship between RR interval and systolic arterial pressure (SAP) during ambulatory blood pressure monitoring could detect alterations in circadian arterial pressure and heart rate profile and could also be linked to the ambulatory arterial stiffness index. METHO...

journal_title：Journal of hypertension

authors： Pizzinelli P,Iellamo F,Beltrami S,Lucini D,Pagani M

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVES:Increased central artery stiffness associates with cardiovascular disease. Among other factors, hypertension and aging are strong contributors to central artery stiffening, yet it has been difficult to separate their effects. Herein, we study isolated and combined effects of hypertension and aging on central...

journal_title：Journal of hypertension

authors： Spronck B,Ferruzzi J,Bellini C,Caulk AW,Murtada SI,Humphrey JD

更新日期：2020-07-01 00:00:00

abstract：:Blood pressure was measured in 864 young people aged 16-24 years, 8 years after both of their parents had their blood pressures measured as part of the screening phase of the Medical Research Council Mild Hypertension Trial. Only 29% of offspring with a conventional 'family history of hypertension', defined in terms o...

journal_title：Journal of hypertension

authors： Watt GC,Foy CJ,Holton DW,Edwards HE

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the role of transforming growth factor (TGF)-beta1 in the development of diabetes-associated mesenteric vascular hypertrophy and in the antitrophic effect of angiotensin converting enzyme inhibitors. DESIGN AND METHODS:Streptozotocin-induced diabetic and control Spragu...

journal_title：Journal of hypertension

authors： Rumble JR,Gilbert RE,Cox A,Wu L,Cooper ME

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Blood pressure (BP)-lowering trials studying efficacy mostly assesses binary outcome events, for example stroke/no stroke. Analysis of ordered categorical vascular events (e.g. three levels: fatal stroke/nonfatal stroke/no stroke) provides information on severity and is more powerful statistically than analy...

journal_title：Journal of hypertension

authors： Geeganage CM,Tracy M,Bath MW,Bath PM

更新日期：2010-10-01 00:00:00