Cause of renal infarction: a retrospective analysis of 186 consecutive cases.

abstract：BACKGROUND:Telmisartan is a unique AT1 receptor blocker with a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonistic action. Activation of PPAR-gamma could prevent inflammation and brain damage. METHOD:We investigated the beneficial effect of telmisartan on ischemic brain damage via PPAR-gamma activa...

journal_title：Journal of hypertension

authors： Iwanami J,Mogi M,Tsukuda K,Min LJ,Sakata A,Jing F,Iwai M,Horiuchi M

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:To determine the benefits and risks of drinking alcohol in treated hypertensives. DESIGN:A prospective study of 6,369 hypertensives (3,161 men) attending primarily hospital clinics in the UK. METHODS:Relative risks both for drinkers compared with non-drinkers and for level of alcohol consumption were calcul...

journal_title：Journal of hypertension

authors： Palmer AJ,Fletcher AE,Bulpitt CJ,Beevers DG,Coles EC,Ledingham JG,Petrie JC,Webster J,Dollery CT

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:To determine the degree to which hypertension is a risk factor for macrovascular and microvascular complications in type 2 diabetes. DESIGN:Observational prospective study. SUBJECTS:Newly diagnosed Type 2 diabetic patients recruited into the UK Prospective Diabetes Study (n = 3648; mean age 52 years), 40% o...

journal_title：Journal of hypertension

authors：

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to define the relationship between physical activity and the magnitude of the percentage fall in blood pressure at night (nocturnal dip). METHODS:We simultaneously monitored 24-h ambulatory blood pressure and measured physical activity by actigraphy in 434 patients. Blood pressure w...

journal_title：Journal of hypertension

authors： Leary AC,Donnan PT,MacDonald TM,Murphy MB

更新日期：2000-04-01 00:00:00

abstract：:To investigate the effects of changes in sodium balance on blood pressure and leucocyte sodium transport, normotensive first-degree relatives of hypertensive patients and control subjects were randomized to receive low- and high-salt diets for 2 weeks, separated by a wash-out period of 2 weeks. High-salt intake failed...

journal_title：Journal of hypertension

authors： Heagerty AM,Alton SM,el-Ashry A,Bing RF,Thurston H,Swales JD

更新日期：1986-06-01 00:00:00

abstract：:Uptake of 45Ca was measured in rings of thoracic aorta from rabbits with hypertension, induced by cellophane perinephritis (Page hypertension: one-kidney, one wrap). Basal 45Ca uptake was increased significantly in the hypertensive group (sham: 100 +/- 3, hypertensive: 133 +/- 11 nmol/g wet weight, n = 6). 45Ca uptake...

journal_title：Journal of hypertension

authors： Dong Y,Wadsworth RM

更新日期：1987-12-01 00:00:00

abstract：:Experimental models of genetic hypertension are used to develop paradigms to study human essential hypertension while removing some of the complexity inherent in the study of human subjects. Since 1991 several quantitative trait loci responsible for blood pressure regulation have been identified in various rat crosses...

journal_title：Journal of hypertension

authors： Dominiczak AF,Clark JS,Jeffs B,Anderson NH,Negrin CD,Lee WK,Brosnan MJ

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVE:To assess the antihypertensive efficacy and safety of the novel AT1 receptor antagonist, telmisartan, compared with that of enalapril in elderly patients with mild to moderate hypertension. DESIGN:A 26-week, multicenter, double-blind, parallel-group, dosage titration study. METHODS:A total of 278 patients a...

journal_title：Journal of hypertension

authors： Karlberg BE,Lins LE,Hermansson K

更新日期：1999-02-01 00:00:00

abstract：AIM:Studies addressing the association between a reduced drop of heart rate (HR) at night with subclinical organ damage and cardiovascular events in the general population are scanty. We evaluated this issue in individuals enrolled in the Pressioni Monitorate E Loro Associazioni study. METHODS:At entry, 2021 individua...

journal_title：Journal of hypertension

authors： Cuspidi C,Facchetti R,Bombelli M,Sala C,Tadic M,Grassi G,Mancia G

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:We examined the relation between cardiovascular reactivity (the response of the cardiovascular system to psychological stress) and the severity and progression of carotid atherosclerosis. METHODS:Using duplex ultrasonography, we measured the change in the area of all detectable plaques in the extracranial c...

journal_title：Journal of hypertension

authors： Barnett PA,Spence JD,Manuck SB,Jennings JR

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVES:To assess the influence of sodium intake on the two components of arterial blood pressure [mean blood pressure (MBP) and pulse pressure] and left ventricular mass (LVM) in normotensive subjects and never-treated hypertensive patients. METHODS:Blood pressure, LVM (M-mode echocardiography) and sodium excretio...

journal_title：Journal of hypertension

authors： du Cailar G,Mimran A,Fesler P,Ribstein J,Blacher J,Safar ME

更新日期：2004-04-01 00:00:00

abstract：:Neutrophils possess a plasma-membrane-bound reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase which catalyzes superoxide (O2-) formation and is activated by a variety of stimuli. Recently, neutrophils of patients with essential hypertension (EHT) have been reported to generate O2- at rates up to four...

journal_title：Journal of hypertension

authors： Seifert R,Hilgenstock G,Fassbender M,Distler A

更新日期：1991-02-01 00:00:00

abstract：:Adequate evaluation of automated sphygmomanometers, in terms of safety, accuracy, mechanical reliability, patient acceptability and ability to record ambulatory blood pressure is essential before these devices are used in clinical practice and in clinical trials. We have evaluated the accuracy and performance of the A...

journal_title：Journal of hypertension

authors： Jamieson MJ,Fowler G,MacDonald TM,Webster J,Witte K,Lawson L,Crichton W,Jeffers TA,Petrie JC

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVE:To explore the mechanisms for augmented neutral endopeptidase inhibitor-induced natriuresis in deoxycorticosterone acetate (DOCA)-salt rats. METHODS:We examined effects of a neutral endopeptidase-inhibitor, candoxatril, on plasma and urinary brain natriuretic peptide (BNP) levels, the influence of a specific...

journal_title：Journal of hypertension

authors： Hirata Y,Suzuki Y,Suzuki E,Hayakawa H,Kimura K,Goto A,Omata M,Minamino N,Kangawa K,Matsuo H

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:We have previously described anatomical changes in pulmonary blood flow distribution in chronic hypoxic rats, associated with pulmonary arterial hypertension (PAH). METHOD:In this study, we utilized synchrotron radiation microangiography to compare these changes in pulmonary blood flow with a PAH-model indu...

journal_title：Journal of hypertension

authors： Schwenke DO,Pearson JT,Shimochi A,Kangawa K,Tsuchimochi H,Umetani K,Shirai M,Cragg PA

更新日期：2009-07-01 00:00:00

abstract：:The effects of essential fatty acid deficiency (EFAD) on vascular reactivity to vasoconstrictor stimuli were studied in rat autoperfused hindquarters. Weanling male Sprague-Dawley rats (aged 21 days) were fed diets containing 8% (weight/weight) of stearax plus 2% safflower oil (control diet) or 10% stearax (EFAD diet)...

journal_title：Journal of hypertension

authors： Kudo K,Dusting GJ,Loiacono RE,Sinclair AJ

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVES:Aortic (central) blood pressure (BP) differs from brachial BP and may be a superior predictor of cardiovascular events. However, its measurement is currently restricted to research settings, owing to a moderate level of operator dependency. We tested a new noninvasive device in a large UK cohort. The device ...

journal_title：Journal of hypertension

authors： Park CM,Korolkova O,Davies JE,Parker KH,Siggers JH,March K,Tillin T,Chaturvedi N,Hughes AD

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Left-ventricular hypertrophy (LVH) is a marker of organ damage in hypertension and helps stratifying cardiovascular risk. Initial left-ventricular mass (LVM) is also a predictor of progression to hypertension, independently of initial blood pressure (BP) and other confounders. OBJECTIVES:To evaluate whether...

journal_title：Journal of hypertension

authors： Izzo R,de Simone G,Devereux RB,Giudice R,De Marco M,Cimmino CS,Vasta A,De Luca N,Trimarco B

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Melatonin, an endogenous neurohormone secreted predominately by the pineal gland, has a variety of physiological functions. However, its protective role in atherosclerosis is not clear. In this study, we sought to investigate the potential effects of melatonin in modulating atherosclerotic plaque stability in...

journal_title：Journal of hypertension

authors： Li H,Li J,Jiang X,Liu S,Liu Y,Chen W,Yang J,Zhang C,Zhang W

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between admission SBP and subsequent cardiovascular and all-cause mortality in older patients hospitalized for acute coronary syndrome (ACS). METHODS:This is a retrospective observational study. Data from the CBD Bank (Cardiovascular Center Beijing Friendship Hospital Database...

journal_title：Journal of hypertension

authors： Jiang C,Wu S,Wang M,Zhao X,Li H

更新日期：2020-11-16 00:00:00

abstract：OBJECTIVE:Smoking is a risk factor for increased carotid artery intima-media thickness (IMT). The apolipoprotein E (apoE) 4 allele has been associated with cardiovascular diseases, but the role of apoE in regard to intima-media thickness (IMT) has remained controversial. The objective was to investigate whether there i...

journal_title：Journal of hypertension

authors： Karvonen J,Kauma H,Kervinen K,Ukkola O,Rantala M,Päivänsalo M,Savolainen MJ,Kesäniemi YA

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To determine whether blood pressure levels in adult life are related to the mother's fetal growth and size at birth. DESIGN:A follow-up study of men and women whose mothers' or fathers' size at birth was recorded in Preston, Lancashire, UK. SUBJECTS:Two hundred and twenty-eight men and women born in Preston...

journal_title：Journal of hypertension

authors： Barker DJ,Shiell AW,Barker ME,Law CM

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVES:The present study aimed to assess the effect of the specific dipeptidyl peptidase IV (DPPIV) inhibitor sitagliptin on blood pressure and renal function in young prehypertensive (5-week-old) and adult spontaneously hypertensive rats (SHRs; 14-week-old). METHODS:Sitagliptin (40 mg/kg twice daily) was given by...

journal_title：Journal of hypertension

authors： Pacheco BP,Crajoinas RO,Couto GK,Davel AP,Lessa LM,Rossoni LV,Girardi AC

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:Underlying pathophysiology of orthostatic hypotension has been poorly understood. We hypothesized that aortic pulse pressure (APP) reflecting aortic stiffness may be involved in the development of orthostatic hypotension. METHODS:A total of 200 patients (age 64.3 ± 10.9 years, 62.5% men) who underwent invasi...

journal_title：Journal of hypertension

authors： Chung J,Kim HL,Lim WH,Seo JB,Kim SH,Zo JH,Kim MA

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Arterial stiffness measures such as pulse wave velocity (PWV) have a known dependence on actual blood pressure, requiring consideration in cardiovascular risk assessment and management. Given the impact of ageing on arterial wall structure, the pressure-dependence of PWV may vary with age. METHODS:Using a n...

journal_title：Journal of hypertension

authors： Spronck B,Heusinkveld MH,Vanmolkot FH,Roodt JO,Hermeling E,Delhaas T,Kroon AA,Reesink KD

更新日期：2015-02-01 00:00:00

abstract：:The effect of haemorrhagic hypotension on plasma catecholamine levels was studied in anesthetized normotensive and DOCA-salt hypertensive rats. The basal levels of plasma norepinephrine (NE) were significantly higher in DOCA-salt hypertensive rats than in normotensive rats. Moreover, the elevations in plasma NE and ep...

journal_title：Journal of hypertension

authors： Drolet G,Bouvier M,de Champlain J

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVES:Visit-to-visit variability of blood pressure (VVV of BP) is an important independent risk factor for premature death and cardiovascular events, but relatively little is known about this phenomenon in patients with chronic kidney disease (CKD) not yet on dialysis. METHODS:We conducted a retrospective study i...

journal_title：Journal of hypertension

authors： Chang TI,Tabada GH,Yang J,Tan TC,Go AS

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:Using an aortic constriction model in mice, we studied whether the increase in pressure or the activation of the renin-angiotensin system (RAS) and its main receptors is the main driving force for plaque progression. METHODS:Male ApoE mice underwent sham surgery or placement of a suprarenal silver clip aroun...

journal_title：Journal of hypertension

authors： Johansson ME,Wickman A,Skøtt O,Gan LM,Bergström G

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:Enhanced central sympathetic outflow is an indicator of the prognosis of heart failure. Although the central sympatholytic drug moxonidine is an established therapeutic strategy for hypertension, its benefits for hypertensive heart failure are poorly understood. In the present study, we investigated the effe...

journal_title：Journal of hypertension

authors： Honda N,Hirooka Y,Ito K,Matsukawa R,Shinohara K,Kishi T,Yasukawa K,Utsumi H,Sunagawa K

更新日期：2013-11-01 00:00:00

abstract：:The reported prevalence of left ventricular hypertrophy (LVH) in human hypertension is much lower than that among animals with experimental hypertension. With current methods of determining left ventricular mass by M-mode echocardiography, the standard error of a single estimate is high and consequently so is the SD o...

journal_title：Journal of hypertension

authors： Korner PI,Jennings GL

更新日期：1998-06-01 00:00:00