Difference in SBP between arms is a predictor of chronic kidney disease development in the general Korean population.

abstract：:The hormonal and hypotensive effects of a single oral 10 mg dose of enalapril (MK-421), were assessed by a double-blind randomized trial in 12 subjects with essential hypertension, during a 100 and 40 mmol/day sodium intake. Peak serum MK-421 appeared 1 h following oral dosage. The bioactive conversion product of MK-4...

journal_title：Journal of hypertension

authors： Jackson B,Cubela R,Johnston CI

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:The aldosterone synthase gene (CYP1B2) locus is a candidate region involved in the development of hypertension. OBJECTIVE:To study the relationship between the C-344T CYP1B2 polymorphism, plasma aldosterone, renin activity and blood pressure in a multi-ethnic population. DESIGN:Population-based, cross-sect...

journal_title：Journal of hypertension

authors： Barbato A,Russo P,Siani A,Folkerd EJ,Miller MA,Venezia A,Grimaldi C,Strazzullo P,Cappuccio FP

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:Elevated blood pressure (BP) is associated with cardiovascular mortality. BP variability (BPV) is also associated with cardiovascular mortality. However, most studies evaluated hypertensive patients with a relatively short follow-up. We investigated in male workers the association between BPV and long-term al...

journal_title：Journal of hypertension

authors： Goldbourt U,Grossman E

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To assess the effect of orlistat plus diet compared with diet alone in promoting weight loss and blood pressure reduction in hypertensive, overweight/obese patients. DESIGN:A pragmatic randomized, controlled trial. SETTING:Hypertension clinic of a university hospital. PATIENTS:Hypertensive patients aged 18...

journal_title：Journal of hypertension

authors： Bloch KV,Salles GF,Muxfeldt ES,Da Rocha Nogueira A

更新日期：2003-11-01 00:00:00

abstract：:Using antibodies raised against angiotensin I and II, and high-performance liquid chromatography (HPLC) of plasma extracts, we have quantified six angiotensin peptides in venous (cubital vein) and arterial (brachial) plasma of normal male subjects. The concentrations of venous plasma (fmol/ml, mean +/- s.d., n = 29) f...

journal_title：Journal of hypertension

authors： Campbell DJ,Kladis A

更新日期：1990-02-01 00:00:00

abstract：OBJECTIVES:Nonsteroidal anti-inflammatory drugs vary in their impact on blood pressure and the effect of lumiracoxib 100 mg once daily has not been studied previously. To examine whether lumiracoxib 100 mg once daily would result in lower 24-h mean systolic ambulatory blood pressure than ibuprofen 600 mg three times da...

journal_title：Journal of hypertension

authors： MacDonald TM,Reginster JY,Littlejohn TW,Richard D,Lheritier K,Krammer G,Rebuli R

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To seek in hypertensive patients rhythmic variations of the systolic blood pressure signal obtained by ambulatory blood pressure monitoring of any inherent cycle of intermediate value between 1 and 24 h. DESIGN:Subjects (62 hypertensive, 39 normotensive) were evaluated by 24-h ambulatory blood pressure monit...

journal_title：Journal of hypertension

authors： Meisel SR,Mor-Avi V,Rosenthal T,Akselrod S

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVES:When assessing arterial stiffness, heart rate (HR) and blood pressure (BP) are potential confounders. It appears that the HR/BP dependences of pulse wave velocity (PWV) and distensibility are different, even though both assess arterial stiffness. This study aims to compare aortic PWV as measured using pulse ...

journal_title：Journal of hypertension

authors： Spronck B,Tan I,Reesink KD,Georgevsky D,Delhaas T,Avolio AP,Butlin M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Inflammatory processes may play a pivotal role in the pathogenesis of cerebrovascular injury in salt-loaded, stroke-prone, spontaneously hypertensive rats (SHRSP). Thromboxane A2 (TP) receptor stimulation by 8-iso-prostaglandin F2alpha (8-iso-PGF2alpha) is involved in the process of vascular inflammation. O...

journal_title：Journal of hypertension

authors： Ishizuka T,Niwa A,Tabuchi M,Nagatani Y,Ooshima K,Higashino H

更新日期：2007-04-01 00:00:00

abstract：:This paper describes the kinetics of the Na(+)-K+ pump and the Na(+)-K(+)-Cl- cotransport in sodium-loaded erythrocytes and of the Na(+)-K(+)-Cl- cotransport in erythrocyte inside-out vesicles (IOV) from Milan hypertensive (MHS) and normotensive (MNS) rats in order to evaluate the possible role of intracellular factor...

journal_title：Journal of hypertension

authors： Ferrari P,Torielli L,Cirillo M,Salardi S,Bianchi G

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVES:To examine a possible relationship between baseline albuminuria and effect of losartan versus atenolol on cardiovascular (CV) events in hypertensive patients with left ventricular hypertrophy, the effect of losartan versus atenolol on albuminuria, and whether the benefits of losartan versus atenolol could be...

journal_title：Journal of hypertension

authors： Ibsen H,Wachtell K,Olsen MH,Borch-Johnsen K,Lindholm LH,Mogensen CE,Dahlöf B,Devereux RB,de Faire U,Fyhrquist F,Julius S,Kjeldsen SE,Lederballe-Pedersen O,Nieminen MS,Omvik P,Oparil S,Wan Y,LIFE substudy.

更新日期：2004-09-01 00:00:00

abstract：:We have examined the mechanisms mediating the release of renin elicited in man by reduction of renal perfusion pressure. Fifteen patients with essential hypertension and six normotensive subjects were investigated during diagnostic renal arteriography. Renal neural receptors were inhibited by propranolol (10 mg i.v.) ...

journal_title：Journal of hypertension

authors： Guazzi MD,Barbier P,Loaldi A,Montorsi P,Polese A,Tosi E,Fiorentini C

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVE:The objective is to evaluate the relationship between cholesterolemia, serum apolipoprotein B (apoB) level and blood pressure in a large sample of general population. METHODS:The Brisighella Heart Study (BHS) is a prospective, population-based longitudinal epidemiological investigation. For this study, we an...

journal_title：Journal of hypertension

authors： Cicero AF,D'Addato S,Veronesi M,Rosticci M,Santi F,Dormi A,Borghi C,Brisighella Heart Study Group.

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:Recent evidence indicates that reduced sleep duration may be associated with an increased risk of hypertension with possibly stronger effects among women than men. We therefore examined cross-sectional sex-specific associations of sleep duration with hypertension in a large population-based sample from the W...

journal_title：Journal of hypertension

authors： Stranges S,Dorn JM,Cappuccio FP,Donahue RP,Rafalson LB,Hovey KM,Freudenheim JL,Kandala NB,Miller MA,Trevisan M

更新日期：2010-05-01 00:00:00

abstract：AIM:Advanced age is associated with vascular endothelial dysfunction, characterized by reductions in the endothelium-dependent vasodilation of the conduit and resistance arteries, in part, from decreased nitric oxide bioavailability. Although vascular smooth muscle function (SMF), assessed by responsiveness to an exoge...

journal_title：Journal of hypertension

authors： Montero D,Pierce GL,Stehouwer CD,Padilla J,Thijssen DH

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:Mean blood pressure varies moderately with outdoor air temperature in many western populations. Substantial uncertainty exists, however, about the strength of the relationship in other populations and its relevance to age, adiposity, medical treatment, climate and housing conditions. METHODS:To investigate ...

journal_title：Journal of hypertension

authors： Lewington S,Li L,Sherliker P,Guo Y,Millwood I,Bian Z,Whitlock G,Yang L,Collins R,Chen J,Wu X,Wang S,Hu Y,Jiang L,Yang L,Lacey B,Peto R,Chen Z,China Kadoorie Biobank study collaboration.

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Few studies have directly compared the effects of different angiotensin receptor blockers (ARBs) on mechanisms involved in the pathogenesis of cardiovascular disease. METHODS:We studied the ability of different ARBs to inhibit the proliferation of vascular smooth muscle cells (VSMCs) and cardiac fibroblasts...

journal_title：Journal of hypertension

authors： Benson SC,Iguchi R,Ho CI,Yamamoto K,Kurtz TW

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Hypertensive disorders during pregnancy are an important risk to mother and fetus, frequently necessitating antihypertensive treatment. Data describing the safety of in-utero exposure to antihypertensive treatment is conflicting with many studies suffering from significant methodological issues. METHOD:We c...

journal_title：Journal of hypertension

authors： Fitton CA,Fleming M,Aucott L,Pell JP,Mackay DF,McLay JS

更新日期：2020-10-09 00:00:00

abstract：OBJECTIVES:Unlike the 2018 European Society of Cardiology/European Society of Hypertension (ESC/ESH) guideline, the 2017 American College of Cardiology/American Heart Association (ACC/AHA) guideline has recommended a shift in hypertension definition from blood pressure (BP) 140/90-130/80 mmHg. Further, they proposed so...

journal_title：Journal of hypertension

authors： Gijón-Conde T,Sánchez-Martínez M,Graciani A,Cruz JJ,López-García E,Ortolá R,Rodríguez-Artalejo F,Banegas JR

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:To assess the expression of early cardiac genes, implicated in the hypertrophic growth response of the adult heart, in peripheral blood mononuclear cells in patients with essential hypertension and its relationship to ambulatory blood pressure monitoring (ABPM) parameters and to echocardiographic left ventri...

journal_title：Journal of hypertension

authors： Kontaraki JE,Marketou ME,Zacharis EA,Parthenakis FI,Vardas PE

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:The mechanisms underlying the relationship between the vascular complications of diabetes and the glycaemic control are not well understood. We tested whether glycaemic control influences the functioning of the nitric oxide system in type 1 diabetic patients and the role for oxidative stress. METHODS:The cha...

journal_title：Journal of hypertension

authors： Rodríguez-Mañas L,López-Dóriga P,Petidier R,Neira M,Solís J,Pavón I,Peiró C,Sánchez-Ferrer CF

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:Development of internally quenched fluorogenic substrates for sensitive and continuous assays of angiotensin I-converting enzyme (ACE). DESIGN:We synthesized internally quenched fluorogenic bradykinin-related peptides introducing Abz (ortho-aminobenzoic acid) and EDDnp (N-[2,4-dinitrophenyl]-ethylenediamine)...

journal_title：Journal of hypertension

authors： Araujo MC,Melo RI,Del Nery E,Alves MF,Juliano MA,Casarini DE,Juliano L,Carmona AK

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:Arterial hypertension is recurrently associated with inflammation of the endothelium as an effect of the upregulation of functional molecules, including cytokines, adhesion molecules and chemokines. However, the role of monocyte chemoattractant protein-1 (MCP-1) in maintaining the inflammatory state of endoth...

journal_title：Journal of hypertension

authors： Tucci M,Quatraro C,Frassanito MA,Silvestris F

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Mineralocorticoid receptor antagonists are increasingly used in patients with treatment-resistant hypertension (TRH). There is experimental evidence for blood pressure (BP) independent effects of mineralocorticoid receptor blockade on cardiovascular target organ damage. We hypothesized that low-dose eplereno...

journal_title：Journal of hypertension

authors： Schneider A,Schwab J,Karg MV,Kalizki T,Reinold A,Schneider MP,Schmieder RE,Schmidt BM

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Experimental data show that ouabain is a modulator of the sodium-potassium pump, which plays an important role in sodium homeostasis and blood pressure regulation. We investigated the distribution of plasma ouabain in the general population in relation to blood pressure and other determinants of sodium homeos...

journal_title：Journal of hypertension

authors： Wang JG,Staessen JA,Messaggio E,Nawrot T,Fagard R,Hamlyn JM,Bianchi G,Manunta P

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Poor adherence to treatment is one of the major problems in the treatment of hypertension. Self blood pressure measurement may help patients to improve their adherence to treatment. METHOD:In this prospective, randomized, controlled study coordinated by a university hospital, a total of 228 mild-to-moderate...

journal_title：Journal of hypertension

authors： van Onzenoort HA,Verberk WJ,Kroon AA,Kessels AG,Nelemans PJ,van der Kuy PH,Neef C,de Leeuw PW

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:Adults with obesity or obesity-related type 2 diabetes (T2DM) are at higher risk for cardiovascular disease possibly due to increased arterial stiffness. We sought to determine if arterial stiffness is increased in youth with obesity or T2DM as compared with lean controls. METHODS:Youth age 10-24 years (N = ...

journal_title：Journal of hypertension

authors： Urbina EM,Kimball TR,Khoury PR,Daniels SR,Dolan LM

更新日期：2010-08-01 00:00:00

abstract：:Hypertension is the most prevalent chronic medical condition and a major risk factor for cardiovascular morbidity and mortality. In the majority of hypertensive cases, the underlying cause of hypertension cannot be easily identified because of the heterogeneous, polygenic and multi-factorial nature of hypertension. Me...

journal_title：Journal of hypertension

authors： Nikolic SB,Sharman JE,Adams MJ,Edwards LM

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:Renal denervation (RDN) can reduce sympathetic activity and blood pressure (BP) in patients with hypertension. The effects on resting and ambulatory heart rate (HR), also regulated by the sympathetic nervous system, are not established. METHODS:Herein, we report 12-month outcomes from the Global SYMPLICITY ...

journal_title：Journal of hypertension

authors： Böhm M,Ukena C,Ewen S,Linz D,Zivanovic I,Hoppe U,Narkiewicz K,Ruilope L,Schlaich M,Negoita M,Schmieder R,Williams B,Zeymer U,Zirlik A,Mancia G,Mahfoud F,Global SYMPLICITY Registry Investigators.

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:Studies were undertaken to clarify the pathophysiologic significance of endogenous endothelin in the control of blood pressure and renal hemodynamics in spontaneously hypertensive rats (SHR). DESIGN:The technique of passive immunization was used to neutralize endogenous endothelin in order to estimate the co...

journal_title：Journal of hypertension

authors： Ohno A,Naruse M,Kato S,Hosaka M,Naruse K,Demura H,Sugino N

更新日期：1992-08-01 00:00:00