Effect of dietary sodium on angiotensin-converting enzyme (ACE) inhibition and the acute hypotensive effect of enalapril (MK-421) in essential hypertension.

abstract：OBJECTIVE:In this randomized, double-blind, crossover study, the antihypertensive efficacy of amlodipine and nifedipine gastrointestinal therapeutic system (GITS) was compared following missed doses. Design and methods In a randomized crossover design, 42 patients were randomized to receive amlodipine (5-10 mg) or the ...

journal_title：Journal of hypertension

authors： Elliott HL,Elawad M,Wilkinson R,Singh SP

更新日期：2002-02-01 00:00:00

abstract：:Arterial aging is associated with a progressive increase in aortic stiffening, which results in a rise in central aortic pressures. Traditionally, blood pressure (BP)-lowering therapy has been directed at brachial rather than central pressures. However, a key contemporary question is whether this strategy is optimal i...

journal_title：Journal of hypertension

authors： Williams B

更新日期：2012-06-01 00:00:00

abstract：:Fenoldopam, a dopamine-1 (D1) agonist, was administered by a 6-h intravenous infusion to patients with refractory hypertension [diastolic blood pressure (DBP) greater than 115 mmHg while on triple therapy] in order to achieve a fall in DBP of 30 mmHg. The evolution of blood pressure, heart rate, glomerular filtration ...

journal_title：Journal of hypertension

authors： Ruilope LM,Robles RG,Miranda B,Tovar J,Alcazar JM,Sancho J,Rodicio JL,Martinez A,Astorga A,Beck T

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Some patients with essential hypertension manifest greater than normal urinary excretion of albumin (UAE). Authors of a few retrospective studies have suggested that there is an association between microalbuminuria and cardiovascular risk. OBJECTIVE:To evaluate whether microalbuminuria is associated with a ...

journal_title：Journal of hypertension

authors： Bigazzi R,Bianchi S,Baldari D,Campese VM

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Hypertensive nephrosclerosis is one of the most frequent causes of chronic kidney failure. Proteome analysis potentially improves the pathophysiological understanding and diagnostic precision of this disorder. In the present exploratory study, we investigated experimental nephrosclerosis in the two-kidney, o...

journal_title：Journal of hypertension

authors： Vethe H,Finne K,Skogstrand T,Vaudel M,Vikse BE,Hultström M,Placier S,Scherer A,Tenstad O,Marti HP

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between stroke risk and blood pressure (BP) levels with regard to the usage of antihypertensive medications. METHODS:From the Japan arteriosclerosis longitudinal study, 11,371 participants from the four population-based cohort studies (aged 40-89) were followed up for a mean of 9....

journal_title：Journal of hypertension

authors： Asayama K,Ohkubo T,Yoshida S,Suzuki K,Metoki H,Harada A,Murakami Y,Ohashi Y,Ueshima H,Imai Y,Japan Arteriosclerosis Longitudinal Study (JALS) group.

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Choice of antihypertensive drugs is also based on the expected burden of adverse events associated with each class of agents, and we have recently identified treatment discontinuation for adverse events as a measure of treatment tolerability frequently reported in randomized controlled trials (RCTs). OBJECT...

journal_title：Journal of hypertension

authors： Thomopoulos C,Parati G,Zanchetti A

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVES:Brachial artery flow-mediated dilation (FMD) is a popular technique to examine endothelial function in humans. Identifying volunteer and methodological factors related to variation in FMD is important to improve measurement accuracy and applicability. METHODS:Volunteer-related and methodology-related parame...

journal_title：Journal of hypertension

authors： van Mil AC,Greyling A,Zock PL,Geleijnse JM,Hopman MT,Mensink RP,Reesink KD,Green DJ,Ghiadoni L,Thijssen DH

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:The inverse association between socioeconomic status (SES) and cardiovascular disease (CVD) risk is well documented. Aortic stiffness assessed by aortic pulse wave velocity (PWV) is a strong predictor of CVD events. However, no previous study has examined the effect of SES on arterial stiffening over time. Th...

journal_title：Journal of hypertension

authors： Trudel X,Shipley MJ,McEniery CM,Wilkinson IB,Brunner EJ

更新日期：2016-10-01 00:00:00

abstract：:: We aimed to combine evidence from all heart failure trials that have investigated the effects of drugs with blood pressure (BP)-lowering properties to assess the extent to which such drugs reduce BP in heart failure, the association between the net change in BP between treatment arms and cause-specific outcomes and ...

journal_title：Journal of hypertension

authors： Pinho-Gomes AC,Azevedo L,Bidel Z,Nazarzadeh M,Canoy D,Copland E,Salam A,Rodgers A,Kotecha D,Rahimi K

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Reductions in albuminuria of more than 30% are considered a strong marker of delay of chronic kidney disease (CKD) progression. Single renin-angiotensin system (RAS) blockade represents the cornerstone of CKD treatment. However, as CKD progression still occurs, other nephroprotective options were explored; m...

journal_title：Journal of hypertension

authors： Alexandrou ME,Papagianni A,Tsapas A,Loutradis C,Boutou A,Piperidou A,Papadopoulou D,Ruilope L,Bakris G,Sarafidis P

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:Traditional cardiovascular risk factors do not fully account for ethnic differences in cardiovascular disease. We tested if arterial function indices, particularly augmentation index (AIx), and their determinants from childhood could underlie such ethnic variability among young British adults in the 'DASH' lo...

journal_title：Journal of hypertension

authors： Faconti L,Silva MJ,Molaodi OR,Enayat ZE,Cassidy A,Karamanos A,Nanino E,Read UM,Dall P,Stansfield B,Harding S,Cruickshank KJ

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:An excess morning blood pressure surge (MBPS) may portend an increased cardiovascular risk, but the mechanisms thereof have been little investigated. The link between MBPS, short-term blood pressure (BP) variability, and arterial stiffness has not been entirely defined. METHODS:In 602 consecutive untreated h...

journal_title：Journal of hypertension

authors： Pucci G,Battista F,Anastasio F,Schillaci G

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:Reflection of the finger pulse wave form is a valid measure of arterial stiffness, which may be continuously assessed during sleep. We investigated the relationships between sleep, sleep-disordered breathing, hypertension, and pulse propagation time (PPT) in patients with suspected sleep apnea. METHODS:The ...

journal_title：Journal of hypertension

authors： Svedmyr S,Zou D,Sommermeyer D,Ficker JH,Randerath W,Fietze I,Sanner B,Hedner J,Grote L

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Hydroxymethylglutaryl coenzyme A (HMGCoA) reductase inhibitors have beneficial effects beyond their cholesterol-lowering properties. The antioxidant mechanism of HMGCoA reductase inhibitors is not completely understood. OBJECTIVES:To elucidate the antioxidant effect of simvastatin. METHODS:We studied the i...

journal_title：Journal of hypertension

authors： Carneado J,Alvarez de Sotomayor M,Perez-Guerrero C,Jimenez L,Herrera MD,Pamies E,Martin-Sanz MD,Stiefel P,Miranda M,Bravo L,Marhuenda E

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:In previous studies we demonstrated that the administration of furosemide associated with L-arginine contributes to enhanced hypotension and induces greater water than electrolyte excretion, in both normal and expansion conditions. The aim of the present study was to elucidate the interaction between furosemi...

journal_title：Journal of hypertension

authors： Costa MA,Loria A,Elesgaray R,Balaszczuk AM,Arranz C

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:Arterial remodeling aims to maintain a constant circumferential wall stress (sigmac). A failing remodeling process is associated with stroke. Data on the relationship between chronic kidney disease and arterial remodeling are scarce. METHODS:We investigated the association between a lower glomerular filtrati...

journal_title：Journal of hypertension

authors： Hermans MM,Henry RM,Dekker JM,Nijpels G,Heine RJ,Stehouwer CD

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:To determine whether insulin sensitivity is impaired in normotensive offspring of essential hypertensives and to investigate how it relates to disturbed calcium metabolism. DESIGN:In 10 young lean, normotensive subjects with family histories of essential hypertension and in 10 age-matched controls we invest...

journal_title：Journal of hypertension

authors： Ohno Y,Suzuki H,Yamakawa H,Nakamura M,Otsuka K,Saruta T

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVES:To investigate whether the combination of exercise training with the angiotensin-converting enzyme inhibitor lisinopril will have an additional beneficial effect on left ventricular function in spontaneously hypertensive rats. DESIGN:Twelve-week-old male rats were assigned to treadmill running (Ht-Ex; 20 m/...

journal_title：Journal of hypertension

authors： Ziada AM

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To determine whether a diuretic can also reverse the clinical, systemic, renal and glomerular haemodynamic and pathological changes caused by nephrosclerosis. METHODS:Three groups of 20-week-old spontaneously hypertensive rats (SHR) were investigated: control male SHR; a similar group, administered 50 mg/l N...

journal_title：Journal of hypertension

authors： Ono Y,Ono H,Frohlich ED

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVES:To test whether the Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene is of functional relevance in humans by altering endothelium-dependent vasodilation. BACKGROUND:The Asp298 variant of the eNOS gene product has been associated with arterial hypertension, coronary artery disease ...

journal_title：Journal of hypertension

authors： Schneider MP,Erdmann J,Delles C,Fleck E,Regitz-Zagrosek V,Schmieder RE

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Recent studies indicated that central SBP could be estimated by radial late-SBP (rSBP2) with a small disparity. However, most of these studies were conducted by SphygmoCor with a transfer function. The agreement between rSBP2 and central SBP was also tested in several invasive studies, but with inconsistent ...

journal_title：Journal of hypertension

authors： Zhang Y,Agnoletti D,Protogerou AD,Wang JG,Topouchian J,Salvi P,Safar ME,Blacher J

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES:Sodium is the mineral that has been, mainly, linked to hypertension and cardiovascular disease. It is found naturally in many foods, but is also used in the food industry and manufacturing. Identification of total sodium intake, as well as 'hidden' sodium intake from food sources early in life is necessary. ...

journal_title：Journal of hypertension

authors： Magriplis E,Farajian P,Pounis GD,Risvas G,Panagiotakos DB,Zampelas A

更新日期：2011-06-01 00:00:00

abstract：:A unique tissue kallikrein-binding protein was identified and partially characterized in the brain and serum of Sprague-Dawley rats and in the serum-free conditioned media of mouse anterior pituitary cells (AtT 20) and rodent neuroblastoma x glioma hybrids (NG108-15). Kallikrein and kallikrein-binding protein(s) form ...

journal_title：Journal of hypertension

authors： Chao J,Chao L

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:A causal relationship has been established between hyperglycemia and cardiovascular diseases, but no threshold has been retained to determine a 'glycemia-associated' cardiovascular risk. Carotid intima-media thickness (CIMT) is an independent predictor for cardiovascular events. High blood pressure is a majo...

journal_title：Journal of hypertension

authors： Tropeano AI,Boutouyrie P,Katsahian S,Laloux B,Laurent S

更新日期：2004-11-01 00:00:00

abstract：AIMS:The addition of an aldosterone receptor antagonist on top of current optimal therapy (based on angiotensin II inhibition) has demonstrated an important clinical benefit in heart failure patients with systolic dysfunction. Whether this finding also applies to heart failure patients with preserved systolic function ...

journal_title：Journal of hypertension

authors： Muñoz-Pacheco P,Ortega-Hernández A,Caro-Vadillo A,Casanueva-Eliceiry S,Aragoncillo P,Egido J,Fernández-Cruz A,Gómez-Garre D

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:In essential hypertensive patients, blunted renal plasma flow responsiveness to angiotensin II suggests a pathologic increase in angiotensin II in the kidneys. This blunting has been associated with the angiotensinogen 235TT genotype. As several measures of renal function decline with age, we sought to determ...

journal_title：Journal of hypertension

authors： Patel TV,Williams GH,Fisher ND

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Few studies have directly compared the effects of different angiotensin receptor blockers (ARBs) on mechanisms involved in the pathogenesis of cardiovascular disease. METHODS:We studied the ability of different ARBs to inhibit the proliferation of vascular smooth muscle cells (VSMCs) and cardiac fibroblasts...

journal_title：Journal of hypertension

authors： Benson SC,Iguchi R,Ho CI,Yamamoto K,Kurtz TW

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:Increased central artery stiffness associates with cardiovascular disease. Among other factors, hypertension and aging are strong contributors to central artery stiffening, yet it has been difficult to separate their effects. Herein, we study isolated and combined effects of hypertension and aging on central...

journal_title：Journal of hypertension

authors： Spronck B,Ferruzzi J,Bellini C,Caulk AW,Murtada SI,Humphrey JD

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:Using an aortic constriction model in mice, we studied whether the increase in pressure or the activation of the renin-angiotensin system (RAS) and its main receptors is the main driving force for plaque progression. METHODS:Male ApoE mice underwent sham surgery or placement of a suprarenal silver clip aroun...

journal_title：Journal of hypertension

authors： Johansson ME,Wickman A,Skøtt O,Gan LM,Bergström G

更新日期：2006-10-01 00:00:00