Evaluating interventions to reduce central aortic pressure, arterial stiffness and morbidity--mortality.

abstract：:Atrial natriuretic peptide (ANP) plays a pivotal role in modulation of vascular function and it is also involved in the pathophysiology of several cardiovascular diseases. We provide an updated overview of the current appraisal of ANP vascular effects in both animal models and humans. We describe the physiological imp...

journal_title：Journal of hypertension

authors： Rubattu S,Calvieri C,Pagliaro B,Volpe M

更新日期：2013-06-01 00:00:00

abstract：AIMS:In order to eventually improve blood pressure (BP) management, the aim of this study was to identify subgroups of type 2 diabetes mellitus (T2DM) patients with distinct trajectories of SBP levels. Identifying subgroups with distinct SBP trajectories helps to better understand the course of SBP levels in T2DM patie...

journal_title：Journal of hypertension

authors： Walraven I,Mast MR,Hoekstra T,Jansen AP,Rauh SP,Rutters FR,van der Heijden AA,Elders PJ,Moll AC,Polak BC,Dekker JM,Nijpels G

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:It has been shown that nitric oxide (NO) plays an important role in the central control of arterial pressure and sympathetic nerve activity. The aim of this study was to determine whether NO can regulate sympathetic nerve activity by an action on pressor neurons within the rostral part of the ventrolateral me...

journal_title：Journal of hypertension

authors： Hirooka Y,Polson JW,Dampney RA

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVES:Some beta-blockers are less effective in reducing central blood pressure than other antihypertensive drugs, which may explain the higher rate of events in subjects randomized to atenolol in recent trials. We hypothesized that nebivolol, a mixed beta-blocker/nitro-vasodilator, would be more effective than ate...

journal_title：Journal of hypertension

authors： Dhakam Z,Yasmin,McEniery CM,Burton T,Brown MJ,Wilkinson IB

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:The objective is to evaluate the relationship between cholesterolemia, serum apolipoprotein B (apoB) level and blood pressure in a large sample of general population. METHODS:The Brisighella Heart Study (BHS) is a prospective, population-based longitudinal epidemiological investigation. For this study, we an...

journal_title：Journal of hypertension

authors： Cicero AF,D'Addato S,Veronesi M,Rosticci M,Santi F,Dormi A,Borghi C,Brisighella Heart Study Group.

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:Abnormal vascular reactivity contributes to the pathophysiology of hypertension and hypertension-related organ damage. As the dietary content of fatty acids may affect the vascular responses, we investigated the relationship of endothelium-independent and endothelium-dependent vasodilation with the fatty acid...

journal_title：Journal of hypertension

authors： Colussi G,Catena C,Dialti V,Mos L,Sechi LA

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:Studies regarding the effects of parity on blood pressure in later life produced conflicting results. The aim of our study is to analyse whether parity influences the prevalence of hypertension in perimenopausal and postmenopausal women. METHODS:One thousand perimenopausal and postmenopausal women (mean age...

journal_title：Journal of hypertension

authors： Giubertoni E,Bertelli L,Bartolacelli Y,Origliani G,Modena MG

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:Excess oxidative stress is one of the major metabolic abnormalities on vascular walls in hypertension and atherosclerosis. In order to further elucidate the endothelial function under oxidative stress, the effect of hydrogen peroxide (H2O2) on expression of two novel endothelium-derived vasorelaxing peptides,...

journal_title：Journal of hypertension

authors： Chun TH,Itoh H,Saito T,Yamahara K,Doi K,Mori Y,Ogawa Y,Yamashita J,Tanaka T,Inoue M,Masatsugu K,Sawada N,Fukunaga Y,Nakao K

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVES:Urocortin 1 (Ucn1) and the sympathetic nervous system both participate in cardiac and circulatory regulation, but little is known about their possible interactions. METHODS:We report the effects of Ucn1 on the cardiac sympathetic nerve activity (CSNA), haemodynamics and plasma catecholamines in normal sheep...

journal_title：Journal of hypertension

authors： Charles CJ,Jardine DL,Nicholls MG,Rademaker MT,Richards AM

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To examine the association between the graded exercise systolic blood pressure (SBP) response and left ventricular (LV) geometric structure in patients with untreated mild hypertension. PARTICIPANTS:The study included 80 sedentary, overweight patients (43 female and 37 male) with unmedicated high normal bloo...

journal_title：Journal of hypertension

authors： Pierson LM,Bacon SL,Sherwood A,Hinderliter AL,Babyak M,Gullette EC,Waugh R,Blumenthal JA

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To investigate the association between long-term exposure to high-level urban traffic noise and blood pressure in preschool children. DESIGN:Normotensive children (n = 1542), aged 3-7 years and attending kindergartens, had their blood pressures and heart rate measured. Mean values of these circulatory variab...

journal_title：Journal of hypertension

authors： Regecová V,Kellerová E

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the effects of acute hyperhomocysteinemia on distensibility and compliance of large peripheral arteries. Isoprostanes generation and antioxidant vitamins were used to assess the role of oxidative stress. DESIGN:A cross-over, double-blind study on distensibility (DC: diste...

journal_title：Journal of hypertension

authors： Arcaro G,Fava C,Dagradi R,Faccini G,Gaino S,Degan M,Lechi C,Lechi A,Minuz P

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:To find an objective, sensitive method for quantifying microvascular alterations associated with level of blood pressure and age. DESIGN:A prospective cross-sectional study. SUBJECTS AND METHODS:Seventy-four previously untreated hypertensive patients, referred to a hospital outpatients department, and 26 no...

journal_title：Journal of hypertension

authors： Stanton AV,Mullaney P,Mee F,O'Brien ET,O'Malley K

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:We studied the vasoconstrictor effects of the thromboxane A2 (TxA2) analogue U46619 in the perfused hind limb of rats under constant flow before and after intravenous injection of irbesartan, an angiotensin II AT1 receptor antagonist, to test whether irbesartan interacts in vivo with the thromboxane A2/prosta...

journal_title：Journal of hypertension

authors： Fukuhara M,Neves LA,Li P,Diz DI,Ferrario CM,Brosnihan KB

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVES:The C825T single nucleotide polymorphism of the G-protein beta3 (GNB3) has been implicated in susceptibility to essential hypertension, through the expression of an alternatively spliced truncated variant. In an effort to clarify earlier inconclusive results, we performed a meta-analysis of population-based ...

journal_title：Journal of hypertension

authors： Bagos PG,Elefsinioti AL,Nikolopoulos GK,Hamodrakas SJ

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Reductions in albuminuria of more than 30% are considered a strong marker of delay of chronic kidney disease (CKD) progression. Single renin-angiotensin system (RAS) blockade represents the cornerstone of CKD treatment. However, as CKD progression still occurs, other nephroprotective options were explored; m...

journal_title：Journal of hypertension

authors： Alexandrou ME,Papagianni A,Tsapas A,Loutradis C,Boutou A,Piperidou A,Papadopoulou D,Ruilope L,Bakris G,Sarafidis P

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:To evaluate whether efficacious counseling methods on sodium restriction can be successfully incorporated into primary care models for the management of hypertension. METHODS:We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, Database of Abstracts of Reviews of Effects and Health Te...

journal_title：Journal of hypertension

authors： Ruzicka M,Hiremath S,Steiner S,Helis E,Szczotka A,Baker P,Fodor G

更新日期：2014-07-01 00:00:00

abstract：:Many physiological variables known or thought to affect erythrocyte Na+,K+-cotransport are altered in pregnancy. The interrelationships of Na+,K+-cotransport and pregnancy were therefore examined. Values were elevated by more than 30% in both second and third trimesters with a return towards non-pregnant levels in the...

journal_title：Journal of hypertension

authors： Gallery ED,Esber RP,Brown MA,Hawkins MR,Ross M

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVE:It has been postulated that hypertension in the spontaneously hypertensive rat (SHR) results from autoimmune damage to the SHR vasculature. The objective of this study was to isolate autoreactive T-cells specific for arterial antigens, and to characterize these cells. DESIGN:The presence of autoreactive T-ce...

journal_title：Journal of hypertension

authors： Ofosu-Appiah W,Ruggiero C,Huang LY

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:Caffeine is the most widely used pharmacologically active substance. Aortic elastic properties and arterial wave reflection are important factors for the efficient performance of the cardiovascular system, as well as prognosticators of cardiovascular risk. We investigated the effect of caffeine on aortic elas...

journal_title：Journal of hypertension

authors： Vlachopoulos C,Hirata K,O'Rourke MF

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:Arterial remodeling aims to maintain a constant circumferential wall stress (sigmac). A failing remodeling process is associated with stroke. Data on the relationship between chronic kidney disease and arterial remodeling are scarce. METHODS:We investigated the association between a lower glomerular filtrati...

journal_title：Journal of hypertension

authors： Hermans MM,Henry RM,Dekker JM,Nijpels G,Heine RJ,Stehouwer CD

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:Salt sensitivity and the magnitude of systolic blood pressure have been linked to haptoglobin (Hp) polymorphism in normotensives. The aim of the present study was to investigate the indices of hypertension, the severity of complications and the occurrence of coronary and peripheral artery disease for the vari...

journal_title：Journal of hypertension

authors： Delanghe JR,Duprez DA,De Buyzere ML,Bergez BM,Callens BY,Leroux-Roels GG,Clement DL

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Several cytokines and adhesion molecules released from endothelium play an important role in inflammation, immune responses, and probably atherogenesis. OBJECTIVE:To determine whether the transcription factor nuclear factor-kappaB mediated expression of these genes involved in the inflammatory response of e...

journal_title：Journal of hypertension

authors： Tomita N,Morishita R,Tomita S,Yamamoto K,Aoki M,Matsushita H,Hayashi S,Higaki J,Ogihara T

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:Visceral artery fibromuscular dysplasia (VA FMD) manifestations range from asymptomatic to life-threatening. The aim of the study is to evaluate the prevalence and clinical characteristics of VA FMD. METHODS:A total of 232 FMD patients enrolled into ongoing ARCADIA-POL study were included in this analysis. A...

journal_title：Journal of hypertension

authors： Warchoł-Celińska E,Pieluszczak K,Pappaccogli M,Soplińska A,Prejbisz A,Dobrowolski P,Klisiewicz A,Kądziela J,Falkowski A,Śmigielski W,Florczak E,Jóźwik-Plebanek K,Michałowska I,Kabat M,Zgorzelski C,Madej K,Nazarewski S,S

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Genetic variability in the gene for aldosterone synthase--a key enzyme in the production of aldosterone--can affect sodium homeostasis and thereby blood pressure. The possibility of impaired aldosterone production for the development of hypertension is of particular relevance in black Afro-Caribbeans exposed...

journal_title：Journal of hypertension

authors： Zhu H,Sagnella GA,Dong Y,Miller MA,Onipinla A,Markandu ND,MacGregor GA

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE AND DESIGN:Remodelling in the media and decreases in connexin (Cx) expression and size of endothelial cells occur in the caudal artery of spontaneously hypertensive rats (SHR). The objective of this study was to determine whether similar changes are found in the aorta and whether effects in both aorta and cau...

journal_title：Journal of hypertension

authors： Rummery NM,Grayson TH,Hill CE

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the 24-h urinary sodium excretion in children of 10-12 years at a school in the north of Portugal and to examine the influence on salt intake and blood pressure of three different educational interventions for 6 months. METHODS:Blood pressure (BP) and sodium excretion in ...

journal_title：Journal of hypertension

authors： Cotter J,Cotter MJ,Oliveira P,Cunha P,Polónia J

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:Increased endothelial production of reactive oxygen species and decreased nitric oxide bioactivity, associated with the upregulation of monocyte chemoattractant protein (MCP)-1 and lectin-like oxidized low-density lipoprotein receptor (LOX)-1, link hypertension with atherogenesis. We investigated whether the...

journal_title：Journal of hypertension

authors： Zhou MS,Schulman IH,Jaimes EA,Raij L

更新日期：2008-03-01 00:00:00

abstract：:This study focuses on the relationship between some aspects of intra-erythrocytic sodium metabolism (intra-erythrocytic Na content, Na,Li-countertransport), blood pressure, and family history of hypertension, in a group of 84 randomly selected school children (45 males, 39 females). Na,Li-countertransport was signific...

journal_title：Journal of hypertension

authors： Trevisan M,Strazzullo P,Cappuccio FP,Di Muro MR,De Colle S,Franzese A,Iacone R,Krogh V

更新日期：1988-03-01 00:00:00

abstract：AIMS:The addition of an aldosterone receptor antagonist on top of current optimal therapy (based on angiotensin II inhibition) has demonstrated an important clinical benefit in heart failure patients with systolic dysfunction. Whether this finding also applies to heart failure patients with preserved systolic function ...

journal_title：Journal of hypertension

authors： Muñoz-Pacheco P,Ortega-Hernández A,Caro-Vadillo A,Casanueva-Eliceiry S,Aragoncillo P,Egido J,Fernández-Cruz A,Gómez-Garre D

更新日期：2013-11-01 00:00:00