Glucose level is a major determinant of carotid intima-media thickness in patients with hypertension and hyperglycemia.

abstract：OBJECTIVES:To determine whether insulin sensitivity is impaired in normotensive offspring of essential hypertensives and to investigate how it relates to disturbed calcium metabolism. DESIGN:In 10 young lean, normotensive subjects with family histories of essential hypertension and in 10 age-matched controls we invest...

journal_title：Journal of hypertension

authors： Ohno Y,Suzuki H,Yamakawa H,Nakamura M,Otsuka K,Saruta T

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that insulin differently modifies vasoconstriction and recovery from vasoconstriction induced by endogenously released versus circulating norepinephrine, and to investigate the time-dependency of its effect METHODS:Healthy male subjects were studied. Norepinephrine was infused for 10 m...

journal_title：Journal of hypertension

authors： van Veen S,Chang PC

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To determine the effects of capillary rarefaction on cardiovascular reactivity and microcirculatory functioning in essential hypertension. DESIGN:Hypertension is associated with abnormal cardiovascular reactivity and increased vasoconstriction. Capillary rarefaction amplifies these abnormalities, which modif...

journal_title：Journal of hypertension

authors： Ciuffetti G,Schillaci G,Innocente S,Lombardini R,Pasqualini L,Notaristefano S,Mannarino E

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:The acute effects of estrogen on hemodynamic responses were studied with emphasis on the sympathoadrenal system and peripheral circulation. DESIGN:Eleven healthy postmenopausal women recruited from the population-based study BEDA were included in this randomized, double-blind, cross-over, placebo-controlled ...

journal_title：Journal of hypertension

authors： Manhem K,Brandin L,Ghanoum B,Rosengren A,Gustafsson H

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to determine whether pulse pressure is a risk factor for coronary artery disease using data from the MRC trial of treatment of mild hypertension, and whether the effect of anti-hypertensive drug therapy on pulse pressure may be a determinant of outcome in treated patients. METHODS:...

journal_title：Journal of hypertension

authors： Millar JA,Lever AF,Burke V

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:Metabolic syndrome is associated with a high risk of cardiovascular disease in hypertension. We evaluated whether metabolic syndrome is associated with early vascular alterations, such as increased peripheral wave reflections and endothelial dysfunction, in untreated essential hypertensive patients. METHODS:...

journal_title：Journal of hypertension

authors： Plantinga Y,Ghiadoni L,Magagna A,Giannarelli C,Penno G,Pucci L,Taddei S,Del Prato S,Salvetti A

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:Caffeine is the most widely used pharmacologically active substance. Aortic elastic properties and arterial wave reflection are important factors for the efficient performance of the cardiovascular system, as well as prognosticators of cardiovascular risk. We investigated the effect of caffeine on aortic elas...

journal_title：Journal of hypertension

authors： Vlachopoulos C,Hirata K,O'Rourke MF

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:In short-term feeding trials, replacement of other macronutrients with monounsaturated fatty acid reduces blood pressure. However, observational studies have not clearly demonstrated a relationship between monounsaturated fatty acid intake and blood pressure. We report associations of monounsaturated fatty ac...

journal_title：Journal of hypertension

authors： Miura K,Stamler J,Brown IJ,Ueshima H,Nakagawa H,Sakurai M,Chan Q,Appel LJ,Okayama A,Okuda N,Curb JD,Rodriguez BL,Robertson C,Zhao L,Elliott P,INTERMAP Research Group.

更新日期：2013-06-01 00:00:00

abstract：:Interstrain restriction fragment length polymorphism was detected after Southern blot hybridization of spontaneously hypertensive (SHR) and control (WKY) rat DNA digested by Bam HI restrictase with a v-fos probe. The SHR genome was characterized by an additional minor band of 4.0 kb. Other restriction fragment length ...

journal_title：Journal of hypertension

authors： Kotelevtsev YV,Brashishkite DA,Spitkovski DD,Kiselev FL,Postnov YV

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:A reduced cardiac output in chronic heart failure (CHF) evokes renal NaCl and water retention, and, therefore, activates mechanisms promoting natriuresis. Atrial natriuretic peptide (ANP) is one such factor. We hypothesized that another NaCl sensitive endogenous natriuretic factor, i.e., marinobufagenin (MBG...

journal_title：Journal of hypertension

authors： Fridman AI,Matveev SA,Agalakova NI,Fedorova OV,Lakatta EG,Bagrov AY

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVES:We examined whether the early initiation of sexual activity is associated with hypertension in US adults, and whether the timing of first menstruation is meaningful in regard of this association. We also assessed the effect modification by ethnicity. METHODS:Using data from 2001 to 2016 National Health and ...

journal_title：Journal of hypertension

authors： Ngueta G,Ndjaboue R

更新日期：2018-12-01 00:00:00

abstract：:To establish the role of angiotensin converting enzyme inhibitors in the management of hypertension in the elderly, 16 patients were treated with captopril in a randomized double-blind placebo-controlled cross-over study. Clinic blood pressure, ambulatory blood pressure, renal function and mental performance, with emp...

journal_title：Journal of hypertension

authors： Cox JP,Duggan J,O'Boyle CA,Mee F,Walsh JB,Coakley D,O'Brien E,O'Malley K

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVE:The genetic background of orthostatic hypotension, an important risk factor for future cardiovascular morbidity and mortality, was investigated. DESIGN AND METHODS:The study subjects comprised 415 community-dwelling individuals, who were free from any cardiovascular complications, aged 50 years or older (mea...

journal_title：Journal of hypertension

authors： Tabara Y,Kohara K,Miki T

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:Increased endothelial production of reactive oxygen species and decreased nitric oxide bioactivity, associated with the upregulation of monocyte chemoattractant protein (MCP)-1 and lectin-like oxidized low-density lipoprotein receptor (LOX)-1, link hypertension with atherogenesis. We investigated whether the...

journal_title：Journal of hypertension

authors： Zhou MS,Schulman IH,Jaimes EA,Raij L

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:High sleep blood pressure (BP) has been suggested to be an independent risk factor for cardiovascular outcomes. To assess the applicability of sleep BP measured using a timer-equipped home device, we investigated the association between home device-measured sleep BP and large artery stiffness. METHODS:We pe...

journal_title：Journal of hypertension

authors： Tabara Y,Matsumoto T,Murase K,Setoh K,Kawaguchi T,Kosugi S,Nakayama T,Hirai T,Wakamura T,Chin K,Matsuda F,Nagahama study group.

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:To assess the impact of various criteria used to define hypertension in community surveys on estimates of prevalence, treatment and control. In particular, this paper examines the effect of using mean versus minimum values; one, two or three examinations; and three different blood pressure levels. DESIGN:A ...

journal_title：Journal of hypertension

authors： Birkett NJ

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:Arterial remodeling aims to maintain a constant circumferential wall stress (sigmac). A failing remodeling process is associated with stroke. Data on the relationship between chronic kidney disease and arterial remodeling are scarce. METHODS:We investigated the association between a lower glomerular filtrati...

journal_title：Journal of hypertension

authors： Hermans MM,Henry RM,Dekker JM,Nijpels G,Heine RJ,Stehouwer CD

更新日期：2008-04-01 00:00:00

abstract：:Behavioral stress and high dietary salt have been reported to increase blood pressure additively in non-human primates. This study was designed to replicate this phenomenon and to assess neuroendocrine correlates and responses to two commonly used antihypertensives, a beta-adrenoceptor blocker and a thiazide diuretic....

journal_title：Journal of hypertension

authors： Turkkan JS,Goldstein DS

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:In clonal animal cells, certain angiotensin receptor blockers (ARB) activate the peroxisome proliferator-activated receptor-gamma (PPARgamma). The aim of this work was to validate that observation in human cells and humans. METHODS:We investigated the induction of in-vitro adipogenesis and the activation of ...

journal_title：Journal of hypertension

authors： Janke J,Schupp M,Engeli S,Gorzelniak K,Boschmann M,Sauma L,Nystrom FH,Jordan J,Luft FC,Sharma AM

更新日期：2006-09-01 00:00:00

abstract：:The effect of xipamide on the intracellular concentration and transmembrane fluxes of Na+ and K+ was studied in 12 normal male subjects, using a double-blind cross-over design. After a run-in period on placebo for 1 week, the subjects were treated with either placebo (n = 6) or xipamide 20 mg once a day (n = 6) for 16...

journal_title：Journal of hypertension

authors： Lijnen P,Hespel P,Fagard R,Staessen J,Goossens W,Lissens W,Amery A

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVE:To determine whether the noradrenergic sympathetic hyperinnervation in the spontaneously hypertensive rat (SHR), a genetic model of essential hypertension, is associated with changes in neurotrophin 3 (NT3) concentrations. METHODS:NT3 levels were measured using a sensitive enzyme-linked immunosorbent assay (...

journal_title：Journal of hypertension

authors： Zhang SH,Rush RA

更新日期：2001-12-01 00:00:00

abstract：:Emotional stress acutely and repetitively causing blood pressure increase or aggravating existing hypertension is usually not reflected by norepinephrine and epinephrine increase but by a sudden rise of dopamine, the third "defensive" catecholamine coping with the damaging neuropsychological and cardiovascular actions...

journal_title：Journal of hypertension

authors： Kuchel O

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To characterize an ATP-sensitive K+ channel at the single-channel and tissue level in the vascular smooth muscle of normotensive and genetically hypertensive rats. METHODS:Age- and sex-matched Wistar-Kyoto (WKY) rats and stroke-prone spontaneously hypertensive rats (SHRSP) were used. Patch-clamp single-chann...

journal_title：Journal of hypertension

authors： Furspan PB,Webb RC

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:To study the interaction between the C(-344)T polymorphism and known determinants (age, body mass and dietary sodium) of blood pressure and plasma aldosterone. DESIGN:Cross-sectional and longitudinal (1980-1995) survey of male workers in southern Italy. SETTING:Medical centre of the Olivetti factories. PAR...

journal_title：Journal of hypertension

authors： Russo P,Siani A,Venezia A,Iacone R,Russo O,Barba G,D'Elia L,Cappuccio FP,Strazzullo P

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVES:Immigration studies can shed light on hypertension development and reveal high-risk populations. To this end, we investigated the association between age at immigration and hypertension occurrence at adolescence among immigrants to Israel. METHODS:We analyzed cross-sectional data on 2 681 294 adolescents as...

journal_title：Journal of hypertension

authors： Peled A,Gordon B,Twig G,Grossman E,Matani D,Derazne E,Afek A

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:To analyze the natriuretic and diuretic response to frusemide in 33 male essential hypertensive patients as a function of basal renal sodium handling and erythrocyte transport system. METHODS:The natriuretic and diuretic response to an oral dose of frusemide (25 mg) was assessed with a simplified method. Uri...

journal_title：Journal of hypertension

authors： Righetti M,Cusi D,Stella P,Rivera R,Bernardi L,del Vecchio L,Bianchi G

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVES:Recent studies have revealed an association between coronary risk factors and both the number and function of bone marrow-derived endothelial progenitor cell (EPC). We investigated the effect of angiotensin II (Ang II) on EPC senescence, leading to the impairment of proliferative activity. METHODS AND RESUL...

journal_title：Journal of hypertension

authors： Imanishi T,Hano T,Nishio I

更新日期：2005-01-01 00:00:00

abstract：:Measurements of exchangeable sodium, arterial pressure and plasma concentrations of active renin, angiotensin II, aldosterone, sodium and potassium were made in 35 hypertensive patients with renal artery stenosis, 30 having unilateral renal arterial lesions. Plasma urea was below 7 mmol/l in 24 of the patients with un...

journal_title：Journal of hypertension

authors： McAreavey D,Brown JJ,Cumming AM,Davies DL,Fraser R,Lever AF,Mackay A,Morton JJ,Robertson JI

更新日期：1983-10-01 00:00:00

abstract：OBJECTIVE:To characterize the in vivo vascular properties of the spontaneously hypertensive rat (SHR) renal vascular bed by examining vascular conductance/resistance responsiveness to vasoactive agents in vivo and determining whether the filtration surface area of glomerular capillaries is reduced. DESIGN AND METHODS:...

journal_title：Journal of hypertension

authors： Kett MM,Bergström G,Alcorn D,Bertram JF,Anderson WP

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:Circulating biomarkers of endothelial dysfunction and inflammation are elevated in late pregnancy in women with preeclampsia. We examined plasma levels of inflammatory cytokines and adhesion molecules in early pregnancy, to assess their ability to predict preeclampsia. METHODS:In a prospective longitudinal s...

journal_title：Journal of hypertension

authors： Carty DM,Anderson LA,Freeman DJ,Welsh PI,Brennand JE,Dominiczak AF,Delles C

更新日期：2012-05-01 00:00:00