Endothelin-specific antibodies decrease blood pressure and increase glomerular filtration rate and renal plasma flow in spontaneously hypertensive rats.

abstract：BACKGROUND:In arteries, agonists such as acetylcholine release an endothelium-derived hyperpolarizing factor (EDHF) that is neither nitric oxide nor prostacyclin. OBJECTIVES:To examine the responses to acetylcholine in segments of forearm veins from patients with chronic renal failure who either had never received dia...

journal_title：Journal of hypertension

authors： Martinez-León JB,Segarra G,Medina P,Vila JM,Lluch P,Peiró M,Otero E,Lluch S

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To compare blood pressure (BP) in adolescence (11-12 years) among the offspring of preeclamptic and normotensive pregnancies. METHOD:SBP and DBP of 181 girls and boys born after pregnancies with preeclampsia were measured and compared with the BP of 356 age-matched girls and boys of normotensive pregnancies....

journal_title：Journal of hypertension

authors： Øglaend B,Forman MR,Romundstad PR,Nilsen ST,Vatten LJ

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Enhanced oxidative stress has been observed in hypertension, but the underlying mechanism has not been fully clarified. OBJECTIVE:To study the relationship between oxygen free radicals and hypertension, using platelets as a tool to measure the cellular production of superoxide anion (O2). DESIGN:Forty pati...

journal_title：Journal of hypertension

authors： Germanò G,Sanguigni V,Pignatelli P,Caccese D,Lenti L,Ragazzo M,Lauro R,Violi F

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the 24-h urinary sodium excretion in children of 10-12 years at a school in the north of Portugal and to examine the influence on salt intake and blood pressure of three different educational interventions for 6 months. METHODS:Blood pressure (BP) and sodium excretion in ...

journal_title：Journal of hypertension

authors： Cotter J,Cotter MJ,Oliveira P,Cunha P,Polónia J

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:This study tests the hypothesis that the transient receptor potential vanilloid subtype 1 channel induced neuropeptide secretion and depressor response are mediated by, at least in part, activation of endoplasmic reticulum associated Ca release receptors, leading to increased cytosolic Ca in dorsal root gangl...

journal_title：Journal of hypertension

authors： Huang W,Wang H,Galligan JJ,Wang DH

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVES:To assess the consequences of malignant hypertension and its evolution with antihypertensive treatment. BACKGROUND:Malignant hypertension can be considered as a model of the effects of very high blood pressure and renin-angiotensin levels on target organs. However, the consequences on the heart have been li...

journal_title：Journal of hypertension

authors： Gosse P,Coulon P,Papaioannou G,Litalien J,Lemetayer P

更新日期：2011-04-01 00:00:00

abstract：:This study determined the influence of baroreflex sensitivity (BRS) on the rate of urinary sodium excretion and plasma renin activity (PRA) in response to a saline infusion in conscious male rabbits specifically bred for high (Group I; n = 7) and low (Group II; n = 10) BRS and in seven control animals. Only Group II s...

journal_title：Journal of hypertension

authors： Weinstock M,Borosh M,Kafri O,Kaczmarczyk G

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVE:In essential hypertension, the mechanical properties of the radial artery have been shown to be largely unaltered, whereas more controversial and less reliable data have been obtained for the common carotid artery. We therefore examined the distensibility/pressure relationships of the predominantly elastic co...

journal_title：Journal of hypertension

authors： Stella ML,Mircoli L,Mangoni AA,Giannattasio C,Ferrari AU,Mancia G

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:End-stage renal disease (ESRD) is characterized by markedly increased sympathetic outflow that contributes to increased cardiovascular mortality in these patients. The central sympatholytic drug moxonidine (MOX) has been shown to reduce muscle sympathetic nerve activity (MSNA) in initial stages of chronic kid...

journal_title：Journal of hypertension

authors： Hausberg M,Tokmak F,Pavenstädt H,Krämer BK,Rump LC

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Left-ventricular hypertrophy (LVH) is a marker of organ damage in hypertension and helps stratifying cardiovascular risk. Initial left-ventricular mass (LVM) is also a predictor of progression to hypertension, independently of initial blood pressure (BP) and other confounders. OBJECTIVES:To evaluate whether...

journal_title：Journal of hypertension

authors： Izzo R,de Simone G,Devereux RB,Giudice R,De Marco M,Cimmino CS,Vasta A,De Luca N,Trimarco B

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Some cases of pseudopheochromocytoma have been described among hypertensive patients with obstructive sleep apnea (OSA). This study examined whether a pathological rise of urinary metanephrines is a common feature in hypertensive OSA patients and, in such a case, whether the ventilation treatment during sleep...

journal_title：Journal of hypertension

authors： Gilardini L,Lombardi C,Redaelli G,Mattaliano P,Fanari P,Cornacchia M,Scacchi M,Mai S,Ferronato P,Parati G,Invitti C

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to identify the time of blood pressure (BP) drop in the orthostatic hypotension test, and to propose a realistic and appropriate duration in the orthostatic hypotension test. METHODS:A total of 879 consecutive patients (61-year-old and 44% women) with positive on the orthostatic...

journal_title：Journal of hypertension

authors： Jang K,Park M,Kim HL

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Increased arterial stiffness is associated with cardiovascular morbidity and mortality among hypertensive patients. OBJECTIVES:To assess the relationship between ambulatory arterial stiffness index (AASI) and subclinical left ventricular (LV) systolic dysfunction assessed by 2-D speckle-tracking echocardiog...

journal_title：Journal of hypertension

authors： Ahmed TAN,Shams-Eddin H,Fathy MA,El-Naggar HM,Kishk YT

更新日期：2020-05-01 00:00:00

abstract：:Reduced nitric oxide bioavailability contributes to endothelial dysfunction and hypertension. The endothelial isoform of nitric oxide synthase (eNOS) is responsible for the production of nitric oxide within the endothelium. Loss of eNOS cofactor tetrahydrobiopterin to initial increase in oxidative stress leads to unco...

journal_title：Journal of hypertension

authors： Li Q,Youn JY,Cai H

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:Data from the Multiple Risk Factor Intervention Trial show an independent direct association between starch intake and blood pressure in American men at higher risk of coronary heart disease. Cross-sectional data from the International Study of Macronutrients and Micronutrients and Blood Pressure (INTERMAP) w...

journal_title：Journal of hypertension

authors： Brown IJ,Elliott P,Robertson CE,Chan Q,Daviglus ML,Dyer AR,Huang CC,Rodriguez BL,Sakata K,Ueshima H,Van Horn L,Zhao L,Stamler J,INTERMAP Research Group.

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Nailfold capillary density was measured at rest and after 4 min circulatory arrest in order to investigate the relationship between sodium-sensitive hypertension and microvessel density. DESIGN:Seventeen sodium-sensitive and 28 sodium-resistant young borderline hypertensive males and 10 normotensive controls...

journal_title：Journal of hypertension

authors： Draaijer P,de Leeuw PW,van Hooff JP,Leunissen KM

更新日期：1993-11-01 00:00:00

abstract：:: We aimed to combine evidence from all heart failure trials that have investigated the effects of drugs with blood pressure (BP)-lowering properties to assess the extent to which such drugs reduce BP in heart failure, the association between the net change in BP between treatment arms and cause-specific outcomes and ...

journal_title：Journal of hypertension

authors： Pinho-Gomes AC,Azevedo L,Bidel Z,Nazarzadeh M,Canoy D,Copland E,Salam A,Rodgers A,Kotecha D,Rahimi K

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:Nifedipine, an L-type calcium channel blocker, is widely used in the treatment of hypertension and coronary heart diseases, and also exhibits an antiplatelet activity. Activation of peroxisome proliferator-activated receptors (PPARs; α, β/δ, and γ) inhibits the platelet aggregation. Therefore, the purpose of ...

journal_title：Journal of hypertension

authors： Shih CY,Lin MH,Fan HC,Chen FC,Chou TC

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Molecular variants of the angiotensinogen (AGT) and the angiotensin II type 1 receptor (ATR) genes have been associated with the risk of coronary artery disease (CAD) and myocardial infarction (MI), but data so far available are conflicting. The primary object of the paper is to verify this possible associati...

journal_title：Journal of hypertension

authors： Olivieri O,Stranieri C,Girelli D,Pizzolo F,Grazioli S,Russo C,Pignatti PF,Corrocher R

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Despite data from animal models and observational studies that are generally supportive for the soy/isoflavones lowering blood pressure (BP) and improving vascular function, the current findings from clinical trials are still inconclusive. OBJECTIVES:To examine whether soy protein with isoflavones or isofla...

journal_title：Journal of hypertension

authors： Liu ZM,Ho SC,Chen YM,Woo J

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:Inflammation is necessary for successful pregnancy; however, excessive inflammation plays a central role in the development of the pregnancy-specific hypertensive disorder preeclampsia. Numerous anti-inflammatory cytokines are decreased in women with preeclampsia but the role of individual cytokines in blood ...

journal_title：Journal of hypertension

authors： Chatterjee P,Kopriva SE,Chiasson VL,Young KJ,Tobin RP,Newell-Rogers K,Mitchell BM

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION:Hypertension in midlife adults is associated with cognitive decline later in life. In individuals treated for hypertension, blood pressure (BP) loads have been associated with end organ damages. This study examines whether BP load inversely correlates with performance in cognitive tasks in normotensive or ...

journal_title：Journal of hypertension

authors： Noriega de la Colina A,Wu R,Desjardins-Crépeau L,Badji A,Lamarre-Cliche M,Doyon J,Bherer L,Girouard H

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Hypertension control is often inadequate in HIV patients. In a contemporary, nationwide cohort of Italian HIV-infected adults, we assessed time trends in hypertension prevalence, awareness, treatment, and control. We also evaluated predictors of cardiovascular events and of new-onset hypertension. METHODS:M...

journal_title：Journal of hypertension

authors： De Socio GV,Ricci E,Maggi P,Parruti G,Celesia BM,Orofino G,Madeddu G,Martinelli C,Menzaghi B,Taramasso L,Bonfanti P,Pucci G,Schillaci G,CISAI study group.

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:We hypothesized that addressing the 24-h relationship between RR interval and systolic arterial pressure (SAP) during ambulatory blood pressure monitoring could detect alterations in circadian arterial pressure and heart rate profile and could also be linked to the ambulatory arterial stiffness index. METHO...

journal_title：Journal of hypertension

authors： Pizzinelli P,Iellamo F,Beltrami S,Lucini D,Pagani M

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:During the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial, patients with hypertension who received amlodipine had similar cardiovascular risks as those who received candesartan. We conducted a post-trial study, the Candesartan Antihypertensive Survival Evaluation in Japan 10-year fol...

journal_title：Journal of hypertension

authors： Liu J,Yasuno S,Oba K,Konda M,Ichihara C,Kitao H,Kuwabara Y,Ueshima K

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:Coronary heart disease (CHD) risk factors have been consistently related to an increase in carotid intima-media thickness (IMT) in selected populations. However, few studies were population-based and furthermore little attention has been given to the influence of CHD risk factors on IMT in low-risk population...

journal_title：Journal of hypertension

authors： Ferrières J,Elias A,Ruidavets JB,Cantet C,Bongard V,Fauvel J,Boccalon H

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:Despite the widespread use of multivitamin supplements, little is known regarding their effects on blood pressure (BP) and the development of hypertension. We, therefore, sought to prospectively investigate how multivitamin use was associated with incident hypertension among middle-aged and older women. METH...

journal_title：Journal of hypertension

authors： Rautiainen S,Wang L,Lee IM,Manson JE,Gaziano JM,Buring JE,Sesso HD

更新日期：2016-08-01 00:00:00

abstract：:The mechanisms involved in the diuretic action of the recently discovered group of atrial natriuretic peptides (ANP) are not entirely clear. To determine whether the diuresis and the changes in blood pressure produced by alpha-human ANP (alpha-hANP) involved a concomitant modification of circulating arginine-vasopress...

journal_title：Journal of hypertension

authors： Gnädinger MP,Weidmann P,Rascher W,Lang RE,Hellmüller B,Uehlinger DE

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:Apoptosis or programmed cell death could be greater than normal in various cardiovascular disorders, particularly in the heart. Apoptosis might contribute to remodeling of blood vessels in hypertension and could participate in regulation of vascular hypertrophy/hyperplasia. OBJECTIVE:To investigate apoptosi...

journal_title：Journal of hypertension

authors： Sharifi AM,Schiffrin EL

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:Circulating biomarkers of endothelial dysfunction and inflammation are elevated in late pregnancy in women with preeclampsia. We examined plasma levels of inflammatory cytokines and adhesion molecules in early pregnancy, to assess their ability to predict preeclampsia. METHODS:In a prospective longitudinal s...

journal_title：Journal of hypertension

authors： Carty DM,Anderson LA,Freeman DJ,Welsh PI,Brennand JE,Dominiczak AF,Delles C

更新日期：2012-05-01 00:00:00