Effects of moxonidine on sympathetic nerve activity in patients with end-stage renal disease.

abstract：OBJECTIVE:Previous studies on multicellular preparations have shown that hypertrophied cardiac muscle from the spontaneously hypertensive rat (SHR) has a prolonged action potential. The first aim of the present study was to determine whether the action potential of isolated left ventricular myocytes was similarly prolo...

journal_title：Journal of hypertension

authors： Brooksby P,Levi AJ,Jones JV

更新日期：1993-06-01 00:00:00

abstract：OBJECTIVE:The increase in blood pressure that accompanies the obese state is almost invariably associated with alterations in metabolism (insulin resistance and dyslipidaemia) and the neurohumoral profile (activation of the renin-angiotensin system, sympathetic overactivity), which potentiate the cardiovascular risk as...

journal_title：Journal of hypertension

authors： Grassi G,Seravalle G,Dell'Oro R,Trevano FQ,Bombelli M,Scopelliti F,Facchini A,Mancia G,CROSS Study.

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between stroke risk and blood pressure (BP) levels with regard to the usage of antihypertensive medications. METHODS:From the Japan arteriosclerosis longitudinal study, 11,371 participants from the four population-based cohort studies (aged 40-89) were followed up for a mean of 9....

journal_title：Journal of hypertension

authors： Asayama K,Ohkubo T,Yoshida S,Suzuki K,Metoki H,Harada A,Murakami Y,Ohashi Y,Ueshima H,Imai Y,Japan Arteriosclerosis Longitudinal Study (JALS) group.

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:To assess the prevalence of episodes of ST-segment depression in a population of consecutive patients with mild-to-moderate essential hypertension who are free of clinical signs of coronary artery disease. METHODS:The study involved 28 Italian centers that enrolled 414 hypertensive patients (aged 50-70 year...

journal_title：Journal of hypertension

authors： Stramba-Badiale M,Bonazzi O,Casadei G,Dal Palù C,Magnani B,Zanchetti A

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVES:To describe patterns of hypertension history in patients with various types of end-stage renal disease (ESRD) and in persons with normal kidney function; and to identify risk factors for the diagnosis 'hypertensive ESRD'. DESIGN:A case-control study. SETTING:Population-based. PARTICIPANTS:Patients with ES...

journal_title：Journal of hypertension

authors： Perneger TV,Whelton PK,Klag MJ

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:In clonal animal cells, certain angiotensin receptor blockers (ARB) activate the peroxisome proliferator-activated receptor-gamma (PPARgamma). The aim of this work was to validate that observation in human cells and humans. METHODS:We investigated the induction of in-vitro adipogenesis and the activation of ...

journal_title：Journal of hypertension

authors： Janke J,Schupp M,Engeli S,Gorzelniak K,Boschmann M,Sauma L,Nystrom FH,Jordan J,Luft FC,Sharma AM

更新日期：2006-09-01 00:00:00

abstract：:Twenty-four adolescent boys with a positive and 40 boys with a negative parental history of hypertension (PH+ and PH-, respectively) were studied at rest and during exercise on a bicycle ergometer at work loads ranging from 25 to 150 W. Each group was divided into fit and unfit categories on the basis of oxygen consum...

journal_title：Journal of hypertension

authors： Molineux D,Steptoe A

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVE:We aimed to investigate whether adjustment for frailty influences the relationship of blood pressure with mortality in elderly patients with type 2 diabetes mellitus (T2DM). METHODS:Patients aged 60 years and older (n = 858) were selected from a prospective observational cohort study of primary care patients...

journal_title：Journal of hypertension

authors： van Hateren KJ,Hendriks SH,Groenier KH,Bakker SJ,Bilo HJ,Kleefstra N,Landman GW

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVES:Patients with end-stage renal-disease under hemodialysis have increased cardiovascular risk and experience severe blood pressure (BP) fluctuations during the dialysis session and the subsequent interdialytic period. BP variability (BPV) may be an additional risk factor for cardiovascular events and prelimina...

journal_title：Journal of hypertension

authors： Karpetas A,Loutradis C,Bikos A,Tzanis G,Koutroumpas G,Lazaridis AA,Mavromatidis K,Liakopoulos V,Papagianni A,Zebekakis P,Ruilope LM,Parati G,Sarafidis PA

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:To compare noninvasive methods to assess pulse wave velocity (PWV) with the invasive gold standard in terms of absolute values, age-related changes, and relationship with subclinical organ damage. METHODS:Invasive aortic PWV (aoPWVinv) was measured in 915 patients undergoing cardiac catheterization (mean ag...

journal_title：Journal of hypertension

authors： Weber T,Wassertheurer S,Hametner B,Parragh S,Eber B

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:Orthostatic hypotension is a common condition associated with adverse cardiovascular and cognitive prognosis. Screening for orthostatic hypotension consists of blood pressure measurements in supine (or sitting) and standing position during clinical consultations. As orthostatic hypotension is a poorly reprodu...

journal_title：Journal of hypertension

authors： Cremer A,Rousseau AL,Boulestreau R,Kuntz S,Tzourio C,Gosse P

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:Cardiovascular risk prediction is deemed fundamental and the assessment of organ damage is emerging as a potentially 'downstream' picture of individual risk. Our aim was to assess the feasibility and value of prediction of coronaropathy [coronary artery disease (CAD)] of integrated cardiovascular ultrasound e...

journal_title：Journal of hypertension

authors： Moreo A,Gaibazzi N,Faggiano P,Mohammed M,Carerj S,Mureddu G,Pigazzani F,Muiesan L,Salvetti M,Cesana F,Faden G,Facchetti R,Giannattasio C,Rigo F

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:To determine the effects of angiotensin II (AII) (1-8) on cytosolic free calcium concentrations in the absence and in the presence of the selective angiotensin subtype 1 (AT1) receptor antagonist losartan and of the selective angiotensin subtype 2-receptor antagonist P-186 in human peripheral blood mononuclea...

journal_title：Journal of hypertension

authors： Lijnen P,Fagard R,Petrov V

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVES:Recent evidence indicates that reduced sleep duration may be associated with an increased risk of hypertension with possibly stronger effects among women than men. We therefore examined cross-sectional sex-specific associations of sleep duration with hypertension in a large population-based sample from the W...

journal_title：Journal of hypertension

authors： Stranges S,Dorn JM,Cappuccio FP,Donahue RP,Rafalson LB,Hovey KM,Freudenheim JL,Kandala NB,Miller MA,Trevisan M

更新日期：2010-05-01 00:00:00

abstract：:Systolic (SBP), diastolic (DBP) and mean [MBP = diastolic + 1/3 (systolic - diastolic)] blood pressures were compared as predictors of all causes of death (ALL) and of deaths from atherosclerotic cardiovascular disease (ACVD) in 2480 men, aged 40-59 years, belonging to three cohorts followed up for 20 years. Both univ...

journal_title：Journal of hypertension

authors： Menotti A,Seccareccia F,Giampaoli S,Giuli B

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of angiotensin II on cyclooxygenase-2 (COX-2) expression in aortic adventitial fibroblasts from normotensive [Wistar-Kyoto (WKY)] rats and spontaneously hypertensive rats (SHRs). METHODS:Protein expression was determined by western blot, mRNA levels by real-time PCR, transcriptional...

journal_title：Journal of hypertension

authors： Beltrán AE,Briones AM,García-Redondo AB,Rodríguez C,Miguel M,Alvarez Y,Alonso MJ,Martínez-González J,Salaices M

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND AND AIM:The prevalence and associated risks of white-coat hypertension (WCH) are still a matter of debate. We aimed to assess differences in prevalence and associated conditions of WCH defined on the basis of the normality of all daytime, night-time, and 24-h blood pressure (BP), only daytime, or only 24-h B...

journal_title：Journal of hypertension

authors： de la Sierra A,Vinyoles E,Banegas JR,Segura J,Gorostidi M,de la Cruz JJ,Ruilope LM

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The screening for primary aldosteronism is based on the aldosterone-renin ratio calculated with the plasma renin activity (PRA) value as denominator. A direct measurement of active renin (DRA) is being used as an alternative to PRA, but its diagnostic performance remains unclear. METHOD:We, therefore compar...

journal_title：Journal of hypertension

authors： Rossi GP,Barisa M,Belfiore A,Desideri G,Ferri C,Letizia C,Maccario M,Morganti A,Palumbo G,Patalano A,Roman E,Seccia TM,Pessina AC,Mantero F,PAPY study Investigators.

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on pneumonia hospitalization in patients with stroke history in Taiwan. METHODS:We conducted a case-crossover study using the National Health Insurance Research Database in Taiwan during the period from...

journal_title：Journal of hypertension

authors： Liu CL,Shau WY,Wu CS,Lai MS

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Small size at birth and greater BMI in childhood are associated with greater brachial blood pressure (BP) in later life. Aortic (central) BP differs from brachial BP and is more predictive of organ damage and cardiovascular events; the relationship between BMI in childhood and central BP is not known. METHO...

journal_title：Journal of hypertension

authors： Howe LD,Chaturvedi N,Lawlor DA,Ferreira DL,Fraser A,Davey Smith G,Tilling K,Hughes AD

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:Sodium is the mineral that has been, mainly, linked to hypertension and cardiovascular disease. It is found naturally in many foods, but is also used in the food industry and manufacturing. Identification of total sodium intake, as well as 'hidden' sodium intake from food sources early in life is necessary. ...

journal_title：Journal of hypertension

authors： Magriplis E,Farajian P,Pounis GD,Risvas G,Panagiotakos DB,Zampelas A

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To examine the interaction of sodium intake with genetic variations of the angiotensinogen gene and hypertension. DESIGN:A community-based case-reference study. SETTING:Two rural Japanese communities. PARTICIPANTS:Non-overweight and non-drinking Japanese men and women: 229 hypertensives and 229 age-, sex- ...

journal_title：Journal of hypertension

authors： Iso H,Harada S,Shimamoto T,Sato S,Kitamura A,Sankai T,Tanigawa T,Iida M,Komachi Y

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Several cytokines and adhesion molecules released from endothelium play an important role in inflammation, immune responses, and probably atherogenesis. OBJECTIVE:To determine whether the transcription factor nuclear factor-kappaB mediated expression of these genes involved in the inflammatory response of e...

journal_title：Journal of hypertension

authors： Tomita N,Morishita R,Tomita S,Yamamoto K,Aoki M,Matsushita H,Hayashi S,Higaki J,Ogihara T

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:Reversibility of the systemic and renal alterations induced by N(omega)-nitro-L-arginine-methyl ester(L-NAME) was assessed by treatment with irbesartan and enalapril (30 and 10 mg/kg per 24 h, respectively) alone or in combination. DESIGN:L-NAME (20 mg/kg per 24 h) was given to rats for 6 weeks and treatment...

journal_title：Journal of hypertension

authors： Jover B,Herizi A,Casellas D,Mimran A

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:To ascertain the relationships between the kinetic properties of erythrocyte Na+-H+ exchange [maximum kinetic energy (Vmax), Michaelis constant (Km) for internal H+ and Hill's coefficient], Na+-Li+ (Vmax and Km for external Na+), and metabolic parameters in normotensive controls and hypertensive subjects. MA...

journal_title：Journal of hypertension

authors： Semplicini A,Ceolotto G,Felice M,Reato S,Valle R,Gebbin A,Fontebasso A,Serena L,Pessina AC

更新日期：1995-12-01 00:00:00

abstract：:BMI represents an internal metabolic and physiological environment that plays a key role in development of high blood pressure (BP) for many Americans. African-American women have a higher prevalence of high BP and being overweight than men or other ethnic groups. This study examines the genetic-environmental interact...

journal_title：Journal of hypertension

authors： Taylor J,Sun YV,Chu J,Mosley TH,Kardia SL

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Poor adherence to treatment is one of the major problems in the treatment of hypertension. Self blood pressure measurement may help patients to improve their adherence to treatment. METHOD:In this prospective, randomized, controlled study coordinated by a university hospital, a total of 228 mild-to-moderate...

journal_title：Journal of hypertension

authors： van Onzenoort HA,Verberk WJ,Kroon AA,Kessels AG,Nelemans PJ,van der Kuy PH,Neef C,de Leeuw PW

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:In this study, we tested the hypothesis that long-term Rho-kinase inhibition would reverse nitro-L-arginine methyl ester-exacerbated nephrosclerosis in spontaneously hypertensive rats and attempted to elucidate the mechanism involved. METHODS:Five groups (each n = 8) were studied: untreated spontaneously hy...

journal_title：Journal of hypertension

authors： Koshikawa S,Nishikimi T,Inaba C,Akimoto K,Matsuoka H

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:The renin-angiotensin system plays an important role in blood pressure control. Recently the mouse Ren-2 renin gene was introduced into the genome of rats, producing low-renin hypertensive animals. The aim of the present study was to characterize the pharmacological and morphological properties of mesenteric ...

journal_title：Journal of hypertension

authors： Thybo NK,Korsgaard N,Mulvany MJ

更新日期：1992-10-01 00:00:00

abstract：DESIGN:Because of uncertainties regarding the complete antihypertensive mechanism of action of beta-adrenoceptor antagonists, the present study determined whether vagal afferent neurons of humans and rats possess beta-adrenoceptors. Such a location would provide an appropriate target for beta-blockers to modulate neuro...

journal_title：Journal of hypertension

authors： Lawrence AJ,Watkins D,Jarrott B

更新日期：1995-06-01 00:00:00