Abstract:
BACKGROUND:Poor adherence to treatment is one of the major problems in the treatment of hypertension. Self blood pressure measurement may help patients to improve their adherence to treatment. METHOD:In this prospective, randomized, controlled study coordinated by a university hospital, a total of 228 mild-to-moderate hypertensive patients were randomized to either a group that performed self-measurements at home in addition to office blood pressure measurements [the self-pressure group (n = 114)] or a group that only underwent office blood pressure measurement [the office pressure group (n = 114)]. Patients were followed for 1 year in which treatment was adjusted, if necessary, at each visit to the physician's office according to the achieved blood pressure. Adherence to treatment was assessed by means of medication event monitoring system TrackCaps. RESULTS:Median adherence was slightly greater in patients from the self-pressure group than in those from the office pressure group (92.3 vs. 90.9%; P = 0.043). Although identical among both groups, in the week directly after each visit to the physician's office, adherence [71.4% (interquartile range 71-79%)] was significantly lower (P < 0.001) than that at the last 7 days prior to each visit [100% (interquartile range 90-100%)]. On the remaining days between the visits, patients from the self-pressure group displayed a modestly better adherence than patients from the office pressure group (97.6 vs. 97.0%; P = 0.024). CONCLUSION:Although self-blood pressure measurement as an adjunct to office blood pressure measurement led to somewhat better adherence to treatment in this study, the difference was only small and not clinically significant. The time relative to a visit to the doctor seems to be a more important predictor of adherence.
journal_name
J Hypertensjournal_title
Journal of hypertensionauthors
van Onzenoort HA,Verberk WJ,Kroon AA,Kessels AG,Nelemans PJ,van der Kuy PH,Neef C,de Leeuw PWdoi
10.1097/HJH.0b013e328334f36bsubject
Has Abstractpub_date
2010-03-01 00:00:00pages
622-7issue
3eissn
0263-6352issn
1473-5598journal_volume
28pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:The aim of the present study was to investigate possible inter-relationships between connective tissue growth factor (CTGF) and aldosterone in vascular and renal damage associated with hypertension. METHOD:Spontaneously hypertensive rats (SHR) were treated with two doses (100 and 30 mg/kg per day) of the min...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e3280112ce5
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:We examined whether the efficacy of low-dose acetylsalicylic acid (aspirin) for primary prevention of cardiovascular events is influenced by blood pressure (BP) using data from patients aged 60-85 years with hypertension, dyslipidemia, and/or diabetes, but without cardiovascular disease of the Japanese Primar...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000002034
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Arterial stiffness is increased with chronic inflammatory disorders. The reduction of inflammation by immunomodulatory therapy is associated with a restoration of arterial function. The aims of the study were to perform a meta-analysis to determine whether arterial stiffness is increased in patients with inf...
journal_title:Journal of hypertension
pub_type: 杂志文章,meta分析
doi:10.1097/HJH.0000000000000867
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:The catalytic alpha and smaller beta subunits of the plasma membrane Na,K-ATPase occur in various molecular forms (alpha1, alpha2, alpha3, beta1 and beta2). The alpha isoforms of the enzyme have varying affinities for ouabain and exist in different tissues with particular distribution patterns. OBJECTIVE:To...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199816020-00003
更新日期:1998-02-01 00:00:00
abstract::The present study investigated the roles of insulin on central cardiovascular regulation. When rats were fed with a high-salt diet for 4 weeks, hypothalamic and pituitary contents of insulin-like immunoreactive substance (ILI) significantly decreased. The plasma concentration of ILI remained unaltered, however. Intrac...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199106000-00006
更新日期:1991-06-01 00:00:00
abstract:OBJECTIVE:In patients with type 2 diabetes mellitus (T2DM), blocking of the renin-angiotensin-aldosterone system (RAAS) has demonstrated efficacy in lowering blood pressure (BP) and urinary albumin excretion rate (UAER). Nonetheless, not all patients successfully respond to RAAS blockade with a reduction in BP and UAER...
journal_title:Journal of hypertension
pub_type: 杂志文章,随机对照试验
doi:10.1097/HJH.0b013e32834a8a25
更新日期:2011-10-01 00:00:00
abstract::The effects on serum ionized calcium (ICa) and pH of different storage conditions of blood or serum, and of physiological influences such as over-ventilation, food intake and dietary sodium intake have been investigated. Temperature and time-related changes in ICa occurred with storage and were minimized by immediate ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:
更新日期:1987-08-01 00:00:00
abstract:OBJECTIVE:To investigate cardiomyocyte hypertrophy and hormonal profile in cardiac hypertrophy resulting from sequentially applied overloads. METHODS:We studied Sprague-Dawley rats with renovascular hypertension (RV), where pressure overload predominates, or deoxycorticosterone acetate (DOCA)-salt (DS), where volume o...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e3282435b1e
更新日期:2007-09-01 00:00:00
abstract::Blood pressure was measured in 864 young people aged 16-24 years, 8 years after both of their parents had their blood pressures measured as part of the screening phase of the Medical Research Council Mild Hypertension Trial. Only 29% of offspring with a conventional 'family history of hypertension', defined in terms o...
journal_title:Journal of hypertension
pub_type: 临床试验,杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVES:Studies regarding the effects of parity on blood pressure in later life produced conflicting results. The aim of our study is to analyse whether parity influences the prevalence of hypertension in perimenopausal and postmenopausal women. METHODS:One thousand perimenopausal and postmenopausal women (mean age...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e32835c1742
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:Overweight/obesity in childhood is suggested to increase risk of hypertension later in life. However, few studies have assessed the effect of trajectories of weight status from childhood to adulthood on adult hypertension. The present study aimed to assess the relationship between weight status change from ch...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000002016
更新日期:2019-06-01 00:00:00
abstract::The purpose of this study was to examine pressor responsiveness in a rabbit model with adrenal perturbation. Adrenals in rabbits were stabbed with a needle, and the rabbits were given water (adrenal-water group) or 0.9% NaCl (adrenal-salt) to drink; additional rabbits were sham-operated and given water (sham-water gro...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-198502000-00014
更新日期:1985-02-01 00:00:00
abstract::Brachial and carotid artery diameters, blood velocities and blood flows were determined by a pulsed-Doppler flowmeter in 22 normotensive and 74 mild to moderate essential hypertensive subjects, aged 46 +/- 8 years. The product age x MAP/1000 (where MAP is mean arterial blood pressure), called 'arterial age' (expressed...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199005000-00009
更新日期:1990-05-01 00:00:00
abstract::Conscious male beagle dogs were given constant intravenous infusions of noradrenaline for 14 days, four receiving 125 ng/kg/min and four 250 ng/kg/min. Before, during and after these infusions dose-response studies were done in which additional noradrenaline was infused at 500, 1000 and 2000 ng/kg/min, each rate for 1...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:
更新日期:1983-06-01 00:00:00
abstract:AIMS:Arterial hypertension is highly prevalent and difficult to control in patients with obstructive sleep apnea (OSA). High sympathoadrenergic activity is a hallmark physiological phenomenon in OSA. We hypothesized that an antihypertensive drug with inhibitory properties on this activity, such as beta blockers (BBs), ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000002629
更新日期:2021-02-01 00:00:00
abstract::We have studied the norepinephrine (NE) uptake processes directly in synaptosomes isolated from the hypothalamus of both Dahl salt-sensitive (DS) and Dahl salt-resistant (DR) rats. Both DS and DR rats were divided into two dietary groups, one high salt diet group and one low salt diet group. NE uptake was highly sodiu...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-198410000-00003
更新日期:1984-10-01 00:00:00
abstract:OBJECTIVE:Data from the Multiple Risk Factor Intervention Trial show an independent direct association between starch intake and blood pressure in American men at higher risk of coronary heart disease. Cross-sectional data from the International Study of Macronutrients and Micronutrients and Blood Pressure (INTERMAP) w...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e32831a7294
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:To investigate predictors of left ventricular mass corrected for height2.7 (LVMI) and left ventricular hypertrophy in patients who were found to be normotensive with both office and 24-h ambulatory blood pressure (BP) measurements. METHODS:A total of 805 consecutive patients were analyzed. All patients under...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/hjh.0b013e3283370e5e
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVES:Angiotensin converting enzyme (ACE) inhibitors reduce neointimal hyperplasia after balloon denudation, but the mechanisms are not completely understood. It has been demonstrated that nuclear oncogenes are induced in the vascular wall in the hours immediately after injury, and that the same genes are induced ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:Endothelin is thought to be related to cardiovascular disease. The purpose of this study was to determine whether endothelin levels could be reduced by a calcium antagonist and a 'natural factor'. DESIGN:Since calcium ionophores can induce endothelin-1 messenger RNA synthesis in cultured endothelial cells, t...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199309000-00012
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:As a new category of blood pressure (BP) classification according to the Seventh Report of The Joint National Committee, prehypertension has aroused people's great concern in recent years due to its associations with increased incidence of cardiovascular disease. However, there is little information about th...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e32834f9dd3
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:Melatonin, an endogenous neurohormone secreted predominately by the pineal gland, has a variety of physiological functions. However, its protective role in atherosclerosis is not clear. In this study, we sought to investigate the potential effects of melatonin in modulating atherosclerotic plaque stability in...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000001979
更新日期:2019-05-01 00:00:00
abstract::Experimental models of genetic hypertension are used to develop paradigms to study human essential hypertension while removing some of the complexity inherent in the study of human subjects. Since 1991 several quantitative trait loci responsible for blood pressure regulation have been identified in various rat crosses...
journal_title:Journal of hypertension
pub_type: 杂志文章,评审
doi:10.1097/00004872-199816121-00003
更新日期:1998-12-01 00:00:00
abstract:OBJECTIVE:Nifedipine, an L-type calcium channel blocker, is widely used in the treatment of hypertension and coronary heart diseases, and also exhibits an antiplatelet activity. Activation of peroxisome proliferator-activated receptors (PPARs; α, β/δ, and γ) inhibits the platelet aggregation. Therefore, the purpose of ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000000007
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The urinary isoflavonoid equol inhibits membrane Na-K-Cl cotransporters at similar concentrations to those at which furosemide inhibits them, but the significance of this action is not known. OBJECTIVE:To investigate the potential salidiuretic and vascular actions of equol in the rat. METHODS:Renal functio...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199715110-00015
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVE:Ethnic minority populations (EMPs) are disproportionally affected by hypertension-mediated complications compared with European host populations (EHPs), which might be due to disparities in hypertension awareness, treatment and control. We conducted a systematic review and meta-analysis to compare awareness, ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000002651
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVE:Different radiologists may show considerable variation in their interpretation of renal angiograms. We therefore wished to establish the reliability of their interpretation. DESIGN:Assessment of the intra- and inter-observer agreement of the interpretation of renal angiograms. SETTING:Tertiary referral univ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199917120-00011
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To compare blood pressure (BP) in adolescence (11-12 years) among the offspring of preeclamptic and normotensive pregnancies. METHOD:SBP and DBP of 181 girls and boys born after pregnancies with preeclampsia were measured and compared with the BP of 356 age-matched girls and boys of normotensive pregnancies....
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e328330052a
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that genetically determined alterations of maternal immune tolerance to a foetal semi-allograft are important for the pathogenesis of hypertensive disorders in pregnancy. DESIGN:A genetic association study was performed to analyse the impact of genetic polymorphisms known to be involve...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/01.hjh.0000188732.52722.5a
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Orthostatic hypotension, blood pressure (BP) variability, and arterial stiffness are three markers of cardiovascular risk beyond the average BP. However, the relationships between these three parameters are not well known. AIM:To examine the relationships between orthostatic hypotension, BP variability, and...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000002374
更新日期:2020-06-01 00:00:00