The role of haem oxygenase in renal vascular reactivity in normotensive and hypertensive rats.

abstract：BACKGROUND:Recent cross-sectional studies have suggested that higher serum sodium levels may be a marker of elevated blood pressure. It is unclear whether serum sodium levels are related to the risk of developing hypertension in the community. METHODS:We investigated the association of serum sodium with longitudinal b...

journal_title：Journal of hypertension

authors： Lago RM,Pencina MJ,Wang TJ,Lanier KJ,D'Agostino RB,Kannel WB,Vasan RS

更新日期：2008-11-01 00:00:00

abstract：:The fall in blood pressure that is commonly observed when groups of hypertensive individuals are followed without treatment is usually ascribed to two sources: regression towards the mean and increasing familiarity of the subject with the assessment process. Any effect of the latter process could bias the results of c...

journal_title：Journal of hypertension

authors： Haynes RB,Logan AG,Flanagan PT,Milne BJ

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVES:The present study aimed to assess the effect of the specific dipeptidyl peptidase IV (DPPIV) inhibitor sitagliptin on blood pressure and renal function in young prehypertensive (5-week-old) and adult spontaneously hypertensive rats (SHRs; 14-week-old). METHODS:Sitagliptin (40 mg/kg twice daily) was given by...

journal_title：Journal of hypertension

authors： Pacheco BP,Crajoinas RO,Couto GK,Davel AP,Lessa LM,Rossoni LV,Girardi AC

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Although 24-h urinary measure to estimate sodium and potassium excretion is the gold standard, it is not practical for large studies. We compared estimates of 24-h sodium and potassium excretion from a single morning fasting urine (MFU) using three different formulae in healthy individuals. M...

journal_title：Journal of hypertension

authors： Mente A,O'Donnell MJ,Dagenais G,Wielgosz A,Lear SA,McQueen MJ,Jiang Y,Xingyu W,Jian B,Calik KB,Akalin AA,Mony P,Devanath A,Yusufali AH,Lopez-Jaramillo P,Avezum A Jr,Yusoff K,Rosengren A,Kruger L,Orlandini A,Rangar

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:Remodeling of small resistance arteries is an early sign of target organ damage in hypertension. Peripheral capillary morphology abnormalities in hypertension are not well studied. The study objective was to determine whether altered capillary morphology is associated with SBP, DBP, or both in individuals wi...

journal_title：Journal of hypertension

authors： Cheng C,Daskalakis C,Falkner B

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:Urinary excretion of angiotensinogen [urine angiotensinogen (UAGT)] has been proposed as a biomarker of intrarenal renin-angiotensin system activity. We investigated the association between UAGT and salt-sensitivity and potassium-sensitivity of blood pressure (BP) among Genetic Epidemiology Network of Salt Se...

journal_title：Journal of hypertension

authors： Rebholz CM,Chen J,Zhao Q,Chen JC,Li J,Cao J,Gabriel Navar L,Lee Hamm L,Gu D,He J,GenSalt Collaborative Research Group.

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVES:This study presents a reliable index inspired by the total variability concept of real analysis in mathematics, called average real variability (ARV), for the prognostic significance of blood pressure variability (BPV) overcoming the pitfalls of the commonly used standard deviation (SD). BACKGROUND:Recent s...

journal_title：Journal of hypertension

authors： Mena L,Pintos S,Queipo NV,Aizpúrua JA,Maestre G,Sulbarán T

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To determine whether a diuretic can also reverse the clinical, systemic, renal and glomerular haemodynamic and pathological changes caused by nephrosclerosis. METHODS:Three groups of 20-week-old spontaneously hypertensive rats (SHR) were investigated: control male SHR; a similar group, administered 50 mg/l N...

journal_title：Journal of hypertension

authors： Ono Y,Ono H,Frohlich ED

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVES:Arterial stiffness is associated with excess morbidity and mortality, independently of other cardiovascular risk factors. Age is the main determinant responsible for arterial wall changes leading to arterial stiffening. Environmental and genetic factors may however influence the magnitude of the effects of a...

journal_title：Journal of hypertension

authors： Lajemi M,Labat C,Gautier S,Lacolley P,Safar M,Asmar R,Cambien F,Benetos A

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:The new arterial hypertension guidelines by the 2017 American College of Cardiology (ACC)/American Heart Association (AHA) changed the definition of isolated diastolic hypertension (IDH). We assessed and compared in a Chinese population the IDH prevalence, newly defined by the 2017 ACC/AHA guidelines versus t...

journal_title：Journal of hypertension

authors： Wu S,Ji C,Shi J,Chen S,Huang Z,Jonas JB

更新日期：2020-10-06 00:00:00

abstract：OBJECTIVES:When assessing arterial stiffness, heart rate (HR) and blood pressure (BP) are potential confounders. It appears that the HR/BP dependences of pulse wave velocity (PWV) and distensibility are different, even though both assess arterial stiffness. This study aims to compare aortic PWV as measured using pulse ...

journal_title：Journal of hypertension

authors： Spronck B,Tan I,Reesink KD,Georgevsky D,Delhaas T,Avolio AP,Butlin M

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:The objective of the present study was to assess the regression of left ventricular hypertrophy (LVH) during antihypertensive treatment, and its relationship with the changes in microalbuminuria. INDIVIDUALS AND METHODS:One hundred and sixty-eight previously untreated patients with echocardiographic LVH, 46 ...

journal_title：Journal of hypertension

authors： Rodilla E,Pascual JM,Costa JA,Martin J,Gonzalez C,Redon J

更新日期：2013-08-01 00:00:00

abstract：UNLABELLED:PURPOSE IDENTIFICATION: Inter-individual variability in blood pressure response to treatment is well documented, but a clinically useful means to distinguish responders from non-responders has been elusive. With the advent of new technologies and genomic knowledge, more investigators are seeking to identify ...

journal_title：Journal of hypertension

authors： Mellen PB,Herrington DM

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:Neuropeptide W (NPW), an endogenous ligand for the G protein-coupled receptor 7 (GPR7), was first found to make important roles in central nerve system. In periphery, NPW was also present and regulated intracellular calcium homeostasis by L-type calcium channels. This study was designed to discover the effect...

journal_title：Journal of hypertension

authors： Ji L,Zhu H,Chen H,Fan W,Chen J,Chen J,Zhu G,Wang J

更新日期：2015-12-01 00:00:00

abstract：:Fenoldopam, a dopamine-1 (D1) agonist, was administered by a 6-h intravenous infusion to patients with refractory hypertension [diastolic blood pressure (DBP) greater than 115 mmHg while on triple therapy] in order to achieve a fall in DBP of 30 mmHg. The evolution of blood pressure, heart rate, glomerular filtration ...

journal_title：Journal of hypertension

authors： Ruilope LM,Robles RG,Miranda B,Tovar J,Alcazar JM,Sancho J,Rodicio JL,Martinez A,Astorga A,Beck T

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVE:To investigate whether and how renin-angiotensin inhibition attenuates renal injury seen in salt-induced hypertension in Dahl salt-sensitive (Dahl-S) rats. METHODS:Dahl-S rats fed a high-salt (4% sodium chloride) diet for 6 weeks were treated with the angiotensin converting enzyme (ACE) inhibitor alacepril o...

journal_title：Journal of hypertension

authors： Hirawa N,Uehara Y,Kawabata Y,Ohshima N,Ono H,Nagata T,Gomi T,Ikeda T,Goto A,Yagi S

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:To explore the repercussion of cardiac denervation on the short-term blood pressure variability in humans, in order to assess the extent to which the variability of blood pressure is linked to the variability of heart rate. METHODS:Beat-to-beat blood pressure and RR interval time were recorded in 16 heart-tr...

journal_title：Journal of hypertension

authors： van de Borne P,Schintgen M,Niset G,Schoenfeld P,Nguyen H,Degré S,Degaute JP

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Left ventricular mass is associated with body size, obesity and blood pressure. Echocardiography is routinely used to estimate this parameter, which is usually indexed to body surface area to allow comparisons to be made between individuals and groups of different body size. However, in obese subjects, using...

journal_title：Journal of hypertension

authors： Whalley GA,Gamble GD,Doughty RN,Culpan A,Plank L,MacMahon S,Sharpe N

更新日期：1999-04-01 00:00:00

abstract：INTRODUCTION:Several renal denervation (RDN) systems are currently under investigation for treatment of hypertension by ablation of renal sympathetic nerves. The procedural efficacy of devices, however, is variable and incompletely understood. This study aimed at investigating procedural and anatomical predictors of RD...

journal_title：Journal of hypertension

authors： Wolf M,Hubbard B,Sakaoka A,Rousselle S,Tellez A,Jiang X,Kario K,Hohl M,Böhm M,Mahfoud F

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:The present study was designed to investigate the effect of nicardipine administration upon systolic blood pressure (SBP) and cardiac hypertrophy in spontaneously hypertensive rats (SHR). DESIGN:SBP, heart: and left ventricle: body weight ratios, the cross-sectional area of cardiocytes, and the ultrastructur...

journal_title：Journal of hypertension

authors： Ferrante F,Bronzetti E,Ciriaco E,Felici L,Amenta F

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVES:Advanced diabetic nephropathy (DN) is characterized by a marked development of cardiovascular and renal disease. These patients are frequently managed by different health professionals with the consequence that the quality of care may differ substantially. To compare the management of cardiovascular risk fac...

journal_title：Journal of hypertension

authors： Minutolo R,Sasso FC,Chiodini P,Cianciaruso B,Carbonara O,Zamboli P,Tirino G,Pota A,Torella R,Conte G,De Nicola L

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVES:Endothelial dysfunction is associated to cardiovascular risk factors and predicts cardiovascular events. Peripheral arterial tonometry (PAT) is a novel noninvasive method to assess endothelial function. However, there is a paucity of data about its reproducibility. The aim of this study was to assess the fea...

journal_title：Journal of hypertension

authors： Brant LC,Barreto SM,Passos VM,Ribeiro AL

更新日期：2013-10-01 00:00:00

abstract：:: Phaeochromocytoma and paraganglioma (PPGL) are chromaffin cell tumours that require timely diagnosis because of their potentially serious cardiovascular and sometimes life- threatening sequelae. Tremendous progress in biochemical testing, imaging, genetics and pathophysiological understanding of the tumours has far-...

journal_title：Journal of hypertension

authors： Lenders JWM,Kerstens MN,Amar L,Prejbisz A,Robledo M,Taieb D,Pacak K,Crona J,Zelinka T,Mannelli M,Deutschbein T,Timmers HJLM,Castinetti F,Dralle H,Widimský J,Gimenez-Roqueplo AP,Eisenhofer G

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:To examine a possible involvement of a regulatory protein of Na+/H+ exchanger (NHE) in the increased renal NHE activity in spontaneously hypertensive rats (SHR), we investigated mRNA expression of inhibitory members of the NHE regulatory protein family, NHERF1 and NHERF2, in the kidney. DESIGN:Prehypertensiv...

journal_title：Journal of hypertension

authors： Kobayashi K,Monkawa T,Hayashi M,Saruta T

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:In previous studies we demonstrated that the administration of furosemide associated with L-arginine contributes to enhanced hypotension and induces greater water than electrolyte excretion, in both normal and expansion conditions. The aim of the present study was to elucidate the interaction between furosemi...

journal_title：Journal of hypertension

authors： Costa MA,Loria A,Elesgaray R,Balaszczuk AM,Arranz C

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:Orthostatic hypotension is a common condition associated with adverse cardiovascular and cognitive prognosis. Screening for orthostatic hypotension consists of blood pressure measurements in supine (or sitting) and standing position during clinical consultations. As orthostatic hypotension is a poorly reprodu...

journal_title：Journal of hypertension

authors： Cremer A,Rousseau AL,Boulestreau R,Kuntz S,Tzourio C,Gosse P

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the consistency between a randomly recruited Western European population and the participants of the Framingham Heart Study, with respect to the rates and determinants of progression to hypertension. METHODS:Among the non-hypertensive individuals enrolled in the Flemish Study on Environment, Gene...

journal_title：Journal of hypertension

authors： Zhang H,Thijs L,Kuznetsova T,Fagard RH,Li X,Staessen JA

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:To compare the anti-hypertensive effect of combination therapy versus a single drug regimen schedule (dose-titration or switching to a different drug class) in type 2 diabetic hypertensive patients with inadequate blood pressure (BP) control on monotherapy. DESIGN:Prospective, randomized, open-fashion, paral...

journal_title：Journal of hypertension

authors： Ruilope LM,de la Sierra A,Moreno E,Fernández R,Garrido J,de la Figuera M,de la Cámara AG,Coca A,Luque-Otero M

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:A recent editorial published by Verma and Strauss, entitled 'Angiotensin receptor blockers and myocardial infarction', examined, through a partial analysis of individual trials, the use of angiotensin receptor blockers (ARBs) in a variety of clinical settings. This editorial was reported widely in the lay pr...

journal_title：Journal of hypertension

authors： Volpe M,Mancia G,Trimarco B

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:Data from the Multiple Risk Factor Intervention Trial show an independent direct association between starch intake and blood pressure in American men at higher risk of coronary heart disease. Cross-sectional data from the International Study of Macronutrients and Micronutrients and Blood Pressure (INTERMAP) w...

journal_title：Journal of hypertension

authors： Brown IJ,Elliott P,Robertson CE,Chan Q,Daviglus ML,Dyer AR,Huang CC,Rodriguez BL,Sakata K,Ueshima H,Van Horn L,Zhao L,Stamler J,INTERMAP Research Group.

更新日期：2009-02-01 00:00:00