Regional variations in hypertension prevalence and management in Germany: results from the German Health Interview and Examination Survey (DEGS1).

abstract：OBJECTIVE:We aimed to investigate associations of childhood pulse pressure (PP) and change in PP status with adult subclinical vascular damage. METHODS:Data were obtained from a population-based cohort of children aged 6-18 years started in 1987. The study constituted 1254 participants who were followed up in 2010-201...

journal_title：Journal of hypertension

authors： Hou D,Yan Y,Liu J,Zhao X,Cheng H,Mi J

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Apoptosis or programmed cell death could be greater than normal in various cardiovascular disorders, particularly in the heart. Apoptosis might contribute to remodeling of blood vessels in hypertension and could participate in regulation of vascular hypertrophy/hyperplasia. OBJECTIVE:To investigate apoptosi...

journal_title：Journal of hypertension

authors： Sharifi AM,Schiffrin EL

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:Based on results of in vitro studies, it has been hypothesized that blockade of the renin-angiotensin system (RAS) promotes the recruitment and differentiation of pre-adipocytes and that increased formation of small insulin-sensitive adipocytes counteracts ectopic deposition of lipids, thereby improving insul...

journal_title：Journal of hypertension

authors： Furuhashi M,Ura N,Takizawa H,Yoshida D,Moniwa N,Murakami H,Higashiura K,Shimamoto K

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the wave reflection characteristics in the aortic arch and common carotid artery of ex-preterm adolescents and assess their relationship to central blood pressure in a cohort followed prospectively since birth. METHODS:Central blood pressures, pulse wave velocity, augmentation index, microvascula...

journal_title：Journal of hypertension

authors： Kowalski RR,Beare R,Mynard JP,Cheong JLY,Doyle LW,Smolich JJ,Cheung MMH

更新日期：2018-07-01 00:00:00

abstract：:The mechanisms resulting in the greater predisposition of male subjects towards hypertension were investigated in different strains of rats with genetic hypertension [spontaneously hypertensive rats of the stroke-prone strain (SHRSP) and spontaneously hypertensive rats (SHR)] and their respective normotensive controls...

journal_title：Journal of hypertension

authors： Ganten U,Schröder G,Witt M,Zimmermann F,Ganten D,Stock G

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Patients with type-2 diabetes have a high prevalence of hypertension and show an elevated incidence of cardiovascular events and nephropathy. OBJECTIVES:Recent randomized trials of antihypertensive therapy providing information about cardiovascular and renal risk in diabetes, blood pressure goals and best s...

journal_title：Journal of hypertension

authors： Zanchetti A,Ruilope LM

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:To investigate the characteristics and expression of transforming growth factor (TGF)-beta receptor subtypes on vascular smooth muscle cells (VSMC) from spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto (WKY) rats. METHODS:The effects of TGF-beta 1 on DNA synthesis were evaluated by [3H]-th...

journal_title：Journal of hypertension

authors： Fukuda N,Kubo A,Izumi Y,Soma M,Kanmatsuse K

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:In this study, we tested the hypothesis that long-term Rho-kinase inhibition would reverse nitro-L-arginine methyl ester-exacerbated nephrosclerosis in spontaneously hypertensive rats and attempted to elucidate the mechanism involved. METHODS:Five groups (each n = 8) were studied: untreated spontaneously hy...

journal_title：Journal of hypertension

authors： Koshikawa S,Nishikimi T,Inaba C,Akimoto K,Matsuoka H

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that insulin differently modifies vasoconstriction and recovery from vasoconstriction induced by endogenously released versus circulating norepinephrine, and to investigate the time-dependency of its effect METHODS:Healthy male subjects were studied. Norepinephrine was infused for 10 m...

journal_title：Journal of hypertension

authors： van Veen S,Chang PC

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:We attempted to determine a valid pharmacological approach for the control of high blood pressure in obese hypertensive patients using two antihypertensive agents with different pharmacological actions. DESIGN:Thirty-two obese hypertensive black women were randomly treated with chlorthalidone or clonidine to...

journal_title：Journal of hypertension

authors： Reisin E,Weed SG

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Chronic diabetes is associated with alterations in autonomic modulation of the cardiovascular system. Although the rat has been used extensively in studies of experimental diabetes, there have been no reports on the changes in autonomic modulation of the cardiovascular function in chronic diabetic rats. OBJ...

journal_title：Journal of hypertension

authors： Fazan R Jr,Dias da Silva VJ,Ballejo G,Salgado HC

更新日期：1999-04-01 00:00:00

abstract：:: Hypertension is a growing health concern worldwide. Established hypertension is a causative factor of heart failure, which is characterized by increased vascular resistance and intractable uncontrolled blood pressure. Hypertension and heart failure have multiple causes and complex pathophysiology but cellular immuni...

journal_title：Journal of hypertension

authors： Rai A,Narisawa M,Li P,Piao L,Li Y,Yang G,Cheng XW

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Dipeptidyl peptidase-4 (DPP4) is a key protein in glucose homeostasis and a pharmacological target in type 2 diabetes mellitus. This study explored whether the novel adipokine soluble DPP4 (sDPP4) can cause endothelial dysfunction, an early marker of impaired vascular reactivity. METHOD:Reactivity was studi...

journal_title：Journal of hypertension

authors： Romacho T,Vallejo S,Villalobos LA,Wronkowitz N,Indrakusuma I,Sell H,Eckel J,Sánchez-Ferrer CF,Peiró C

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:To examine the influence of genetic factors on plasma leptin levels. SUBJECTS AND METHODS:We measured plasma leptin levels, body mass index and body fat distribution in healthy young female monozygotic (n = 19) and dizygotic (n = 14) twins. The twin zygosity was verified by determination of short tandem repe...

journal_title：Journal of hypertension

authors： Narkiewicz K,Szczech R,Winnicki M,Chrostowska M,Pawlowski R,Lysiak-Szydlowska W,Choe I,Kato M,Sivitz WI,Krupa-Wojciechowska B,Somers VK

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:Caffeine is the most widely used pharmacologically active substance. Aortic elastic properties and arterial wave reflection are important factors for the efficient performance of the cardiovascular system, as well as prognosticators of cardiovascular risk. We investigated the effect of caffeine on aortic elas...

journal_title：Journal of hypertension

authors： Vlachopoulos C,Hirata K,O'Rourke MF

更新日期：2003-03-01 00:00:00

abstract：:The binding of 125I-angiotensin II to human blood cells was investigated. Blood was drawn from healthy volunteers and platelets prepared with minimal contamination of red cells and white blood cells (less than 0.1%). Using thin layer chromatography, degradation of 125I-angiotensin II by platelets could be demonstrated...

journal_title：Journal of hypertension

authors： Mann JF,Sis J,Ritz E

更新日期：1985-04-01 00:00:00

abstract：OBJECTIVES:Strong evidence has secured aging as a powerful predictor of both cardiovascular risk and endothelial dysfunction, yet specific treatment is not available. We tested the hypothesis that vascular responsiveness to flavanol-rich cocoa increases with advancing age. We have previously shown that flavanol-rich co...

journal_title：Journal of hypertension

authors： Fisher ND,Hollenberg NK

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:End-stage renal disease (ESRD) is characterized by markedly increased sympathetic outflow that contributes to increased cardiovascular mortality in these patients. The central sympatholytic drug moxonidine (MOX) has been shown to reduce muscle sympathetic nerve activity (MSNA) in initial stages of chronic kid...

journal_title：Journal of hypertension

authors： Hausberg M,Tokmak F,Pavenstädt H,Krämer BK,Rump LC

更新日期：2010-09-01 00:00:00

abstract：UNLABELLED:PURPOSE IDENTIFICATION: Inter-individual variability in blood pressure response to treatment is well documented, but a clinically useful means to distinguish responders from non-responders has been elusive. With the advent of new technologies and genomic knowledge, more investigators are seeking to identify ...

journal_title：Journal of hypertension

authors： Mellen PB,Herrington DM

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:Microalbuminuria (MA) is a marker of adverse outcome in hypertension. The aim of this study was to investigate the association of MA with cardiovascular risk factors and glomerular hyperfiltration in the early stage of hypertension and to assess its predictive value for the development of sustained hypertensi...

journal_title：Journal of hypertension

authors： Palatini P,Mormino P,Mos L,Mazzer A,Dorigatti F,Zanata G,Longo D,Garbelotto R,De Toni R,Graniero G,Pessina AC,HARVEST Study Group.

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE AND DESIGN:Remodelling in the media and decreases in connexin (Cx) expression and size of endothelial cells occur in the caudal artery of spontaneously hypertensive rats (SHR). The objective of this study was to determine whether similar changes are found in the aorta and whether effects in both aorta and cau...

journal_title：Journal of hypertension

authors： Rummery NM,Grayson TH,Hill CE

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In 68 randomized controlled trials (RCTs), blood pressure (BP) lowering was obtained by using drugs of different classes. We have investigated whether BP lowering by any of the major drug classes is effective in reducing the cardiovascular outcomes. METHODS:A total of 55 RCTs (19,5 267 indivi...

journal_title：Journal of hypertension

authors： Thomopoulos C,Parati G,Zanchetti A

更新日期：2015-02-01 00:00:00

abstract：:The effects on serum ionized calcium (ICa) and pH of different storage conditions of blood or serum, and of physiological influences such as over-ventilation, food intake and dietary sodium intake have been investigated. Temperature and time-related changes in ICa occurred with storage and were minimized by immediate ...

journal_title：Journal of hypertension

authors： Shore AC,Booker J,Sagnella GA,Markandu ND,MacGregor GA

更新日期：1987-08-01 00:00:00

abstract：OBJECTIVE:Hypertensive nephropathy is one of the major causes of chronic kidney disease (CKD). Bisphenol A (BPA) is associated with elevated blood pressure and urinary albuminuria. The aim of this study is to evaluate the association between serum BPA with the progression of CKD in patients with primary hypertension. ...

journal_title：Journal of hypertension

authors： Hu J,Wang Y,Xiang X,Peng C,Gao R,Goswami R,Zhou H,Zhang Y,Zhen Q,Cheng Q,Yang S,Li Q

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND AIM:Ambulatory blood pressure monitoring (ABPM) is superior to conventional BP measurement in predicting outcome, with baseline 24-h, daytime and night-time absolute values, as well as relative nocturnal decline, as powerful determinants of prognosis. We aimed to evaluate ABPM estimates on the appearance...

journal_title：Journal of hypertension

authors： de la Sierra A,Banegas JR,Segura J,Gorostidi M,Ruilope LM,CARDIORISC Event Investigators.

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:Recent studies have revealed an association between coronary risk factors and both the number and function of bone marrow-derived endothelial progenitor cell (EPC). We investigated the effect of angiotensin II (Ang II) on EPC senescence, leading to the impairment of proliferative activity. METHODS AND RESUL...

journal_title：Journal of hypertension

authors： Imanishi T,Hano T,Nishio I

更新日期：2005-01-01 00:00:00

abstract：:This study focuses on the relationship between some aspects of intra-erythrocytic sodium metabolism (intra-erythrocytic Na content, Na,Li-countertransport), blood pressure, and family history of hypertension, in a group of 84 randomly selected school children (45 males, 39 females). Na,Li-countertransport was signific...

journal_title：Journal of hypertension

authors： Trevisan M,Strazzullo P,Cappuccio FP,Di Muro MR,De Colle S,Franzese A,Iacone R,Krogh V

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVES:We aimed to determine the association of nonalcoholic fatty liver disease (NAFLD) with central and peripheral blood pressure (BP), in a general adolescent population and to examine whether associations are independent of adiposity. METHODS:Using cross-sectional data from a subsample (N = 1904) of a UK birth...

journal_title：Journal of hypertension

authors： Patel S,Lawlor DA,Ferreira DL,Hughes AD,Chaturvedi N,Callaway M,Day C,Sattar N,Fraser A

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:Age, hypertension, diabetes mellitus and a history of cardiovascular disease are the most important factors related to the presence of cerebral white matter lesions (WML), which are a common finding in elderly people. This study investigates which factors related to hypertension per se are associated with the...

journal_title：Journal of hypertension

authors： Sierra C,de La Sierra A,Mercader J,Gómez-Angelats E,Urbano-Márquez A,Coca A

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:To determine whether taurine reduces blood pressure by stimulating the renal kallikrein-kinin system. METHODS:The effects of taurine on blood pressure, urinary kallikrein activity and renal kallikrein gene expression were investigated in Dahl salt-sensitive (Dahl-S) rats. The specificity of the action of tau...

journal_title：Journal of hypertension

authors： Ideishi M,Miura S,Sakai T,Sasaguri M,Misumi Y,Arakawa K

更新日期：1994-06-01 00:00:00