Increased aortic wave reflection contributes to higher systolic blood pressure in adolescents born preterm.

Abstract:

OBJECTIVE:To evaluate the wave reflection characteristics in the aortic arch and common carotid artery of ex-preterm adolescents and assess their relationship to central blood pressure in a cohort followed prospectively since birth. METHODS:Central blood pressures, pulse wave velocity, augmentation index, microvascular reactive hyperemia, arterial distensibility, compliance and stiffness index, and also aortic and carotid wave intensity were measured in 18-year-olds born extremely preterm at below 28 weeks' gestation (n = 76) and term-born controls (n = 42). RESULTS:Compared with controls, ex-preterm adolescents had higher central systolic (111 ± 11 vs. 105 ± 10 mmHg; P < 0.001) and diastolic blood pressures (73 ± 7 vs. 67 ± 7 mmHg; P < 0.001). Although conventional measures of arterial function and biomechanics such as pulse wave velocity and augmentation index were no different between groups, wave intensity analysis revealed elevated backward compression wave area (-0.39 ± 0.21 vs. -0.29 ± 0.17 W/m/s × 10; P = 0.03), backward compression wave pressure change (9.0 ± 3.5 vs. 6.6 ± 2.5 mmHg; P = 0.001) and reflection index (0.44 ± 0.15 vs. 0.32 ± 0.08; P < 0.001) in the aorta of ex-preterm adolescents compared with controls. These changes were less pronounced in the carotid artery. On multivariable analysis, forward and backward compression wave areas were the only biomechanical variables associated with central systolic pressure. CONCLUSIONS:Ex-preterm adolescents demonstrate elevated wave reflection indices in the aortic arch, which correlate with central systolic pressure. Wave intensity analysis may provide a sensitive novel marker of evolving vascular dysfunction in ex-preterm survivors.

journal_name

J Hypertens

journal_title

Journal of hypertension

authors

Kowalski RR,Beare R,Mynard JP,Cheong JLY,Doyle LW,Smolich JJ,Cheung MMH

doi

10.1097/HJH.0000000000001719

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

1514-1523

issue

7

eissn

0263-6352

issn

1473-5598

journal_volume

36

pub_type

杂志文章
  • Patterns of treatment modifications among newly treated hypertensive patients: does choice of modification strategy affect likelihood of treatment discontinuation?

    abstract:OBJECTIVES:Treatment modifications--addition, uptitration, switching, and downtitration--are necessary to address issues such as unattained blood pressure goals, adverse drug events, drug cost, or patient dissatisfaction which lead to treatment discontinuation. This study assessed the patterns of treatment modification...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000000806

    authors: Sonawane KB,Qian J,Garza KB,Wright BM,Zeng P,Ganduglia-Cazaban CM,Hansen RA

    更新日期:2016-03-01 00:00:00

  • Predictors of mortality in patients with type 2 diabetes with or without diabetic nephropathy: a follow-up study.

    abstract:OBJECTIVE:To evaluate the prognostic significance of cardiovascular risk factors including 24-h ambulatory blood pressure level and rhythm for all-cause mortality in type 2 diabetic patients. METHODS:In a prospective observational study, 104 patients with type 2 diabetes were followed: 51 patients with diabetic nephro...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e3282f06428

    authors: Astrup AS,Nielsen FS,Rossing P,Ali S,Kastrup J,Smidt UM,Parving HH

    更新日期:2007-12-01 00:00:00

  • The cardiovascular responses to sequential inhibition of alpha-adrenoceptors, the renin-angiotensin system and vasopressin in rats with adrenal regeneration hypertension.

    abstract::The cardiovascular responses to selective alpha 1- and alpha 2-adrenoceptor antagonism (with prazosin and idazoxan, respectively) were assessed in rats 4 weeks after unilateral nephro-adrenalectomy, contralateral adrenal enucleation and the provision of a 1% NaCl solution as drinking fluid (AEN rats) and in sham-opera...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:

    authors: Foulkes R,Gardiner SM,Bennett T

    更新日期:1988-04-01 00:00:00

  • Adrenocorticotrophin dose-response relationships in the rat: haemodynamic, metabolic and hormonal effects.

    abstract:OBJECTIVE:To determine adrenocorticotrophin dose-response relationships for increase of blood pressure and metabolic parameters of the Sprague-Dawley rat. METHODS:We injected 120 male Sprague-Dawley rats twice daily subcutaneously for 10 days with 0.5, 1, 5, 50, 100, 200 or 500 microg/kg synthetic adrenocorticotrophin...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199816050-00006

    authors: Turner SW,Wen C,Li M,Fraser TB,Whitworth JA

    更新日期:1998-05-01 00:00:00

  • Prediction of high blood pressure in young people: the limited usefulness of parental blood pressure data.

    abstract::Blood pressure was measured in 864 young people aged 16-24 years, 8 years after both of their parents had their blood pressures measured as part of the screening phase of the Medical Research Council Mild Hypertension Trial. Only 29% of offspring with a conventional 'family history of hypertension', defined in terms o...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章

    doi:

    authors: Watt GC,Foy CJ,Holton DW,Edwards HE

    更新日期:1991-01-01 00:00:00

  • Quinapril treatment enhances vascular sensitivity to insulin.

    abstract:OBJECTIVE:Insulin-mediated vasodilation has been shown to be impaired with hypertension and aggravated by dietary sodium restriction. Whether vascular insulin resistance in this setting could be improved by antihypertensive therapy was unknown. Therefore, we determined the effect of therapy with an angiotensin-converti...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004872-200101000-00015

    authors: Feldman RD,Schmidt ND

    更新日期:2001-01-01 00:00:00

  • Clinic-daytime blood pressure difference and cardiovascular damage.

    abstract:OBJECTIVE:To investigate whether the clinic-daytime blood pressure difference can provide information on vascular reactivity to stress comparable to that of simple noninvasive stimuli such as a cold pressor test and isometric exercise, and whether there is any relationship between this blood pressure difference and non...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199917030-00005

    authors: Guida L,Iannuzzi R,Crivaro M,Gaeta I,Pasanisi F,Celentano A,Marotta T,Ferrara LA

    更新日期:1999-03-01 00:00:00

  • Influence of irbesartan and enalapril on changes of renal function associated with the established phase of l-NAME hypertension.

    abstract:OBJECTIVE:Reversibility of the systemic and renal alterations induced by N(omega)-nitro-L-arginine-methyl ester(L-NAME) was assessed by treatment with irbesartan and enalapril (30 and 10 mg/kg per 24 h, respectively) alone or in combination. DESIGN:L-NAME (20 mg/kg per 24 h) was given to rats for 6 weeks and treatment...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200111000-00015

    authors: Jover B,Herizi A,Casellas D,Mimran A

    更新日期:2001-11-01 00:00:00

  • Is it time to measure microalbuminuria in hypertension?

    abstract::Former guidelines on hypertension never made a commitment to the detection of microalbuminuria for screening or follow-up of hypertensive patients. On the other hand, growing evidence support the contributory role of microalbuminuria in the prediction of absolute cardiovascular risk in hypertension and document the po...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1097/00004872-200307000-00001

    authors: Volpe M,Cosentino F,Ruilope LM

    更新日期:2003-07-01 00:00:00

  • Pressure overload causes cardiac hypertrophy in beta1-adrenergic and beta2-adrenergic receptor double knockout mice.

    abstract:OBJECTIVE:Cardiac hypertrophy arises as an adaptive response to increased afterload. Studies in knockout mice have shown that catecholamines, but not alpha1-adrenergic receptors, are necessary for such an adaptation to occur. However, whether beta-adrenergic receptors are critical for the development of cardiac hypertr...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/01.hjh.0000203843.41937.2a

    authors: Palazzesi S,Musumeci M,Catalano L,Patrizio M,Stati T,Michienzi S,Di Certo MG,Mattei E,Vitelli L,Marano G

    更新日期:2006-03-01 00:00:00

  • Increased vascular reactivity induced by essential fatty acid deficiency in rat autoperfused hindquarters.

    abstract::The effects of essential fatty acid deficiency (EFAD) on vascular reactivity to vasoconstrictor stimuli were studied in rat autoperfused hindquarters. Weanling male Sprague-Dawley rats (aged 21 days) were fed diets containing 8% (weight/weight) of stearax plus 2% safflower oil (control diet) or 10% stearax (EFAD diet)...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:

    authors: Kudo K,Dusting GJ,Loiacono RE,Sinclair AJ

    更新日期:1988-02-01 00:00:00

  • Blunted parasympathetic modulation in salt-sensitive patients with essential hypertension: evaluation by power-spectral analysis of heart-rate variability.

    abstract:OBJECTIVE:To evaluate autonomic nervous function by power-spectral analysis of heart-rate variability in salt-sensitive and non-salt-sensitive patients with essential hypertension under the conditions of low and high salt intakes. DESIGN AND METHODS:The blood pressures, heart rates, and electrocardiogram R-R intervals...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199715070-00004

    authors: Minami J,Kawano Y,Ishimitsu T,Takishita S

    更新日期:1997-07-01 00:00:00

  • Apoptosis in aorta of deoxycorticosterone acetate-salt hypertensive rats: effect of endothelin receptor antagonism.

    abstract:BACKGROUND:Apoptosis or programmed cell death could be greater than normal in various cardiovascular disorders, particularly in the heart. Apoptosis might contribute to remodeling of blood vessels in hypertension and could participate in regulation of vascular hypertrophy/hyperplasia. OBJECTIVE:To investigate apoptosi...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199715120-00011

    authors: Sharifi AM,Schiffrin EL

    更新日期:1997-12-01 00:00:00

  • Does the association between birth weight and blood pressure increase with age? A longitudinal study in young adults.

    abstract:OBJECTIVES:To assess whether the association between birth weight and blood pressure (BP) increases with age using three different statistical methods. METHODS:A representative sample of 1232 study participants born between 1974-1978 in Limache, Chile were assessed in 2000-2002, of whom 796 were reassessed in 2010-201...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000000912

    authors: Bustos P,Amigo H,Bangdiwala SI,Pizarro T,Rona RJ

    更新日期:2016-06-01 00:00:00

  • Vascular stiffness determined from a nocturnal digital pulse wave signal: association with sleep, sleep-disordered breathing, and hypertension.

    abstract:OBJECTIVES:Reflection of the finger pulse wave form is a valid measure of arterial stiffness, which may be continuously assessed during sleep. We investigated the relationships between sleep, sleep-disordered breathing, hypertension, and pulse propagation time (PPT) in patients with suspected sleep apnea. METHODS:The ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000001111

    authors: Svedmyr S,Zou D,Sommermeyer D,Ficker JH,Randerath W,Fietze I,Sanner B,Hedner J,Grote L

    更新日期:2016-12-01 00:00:00

  • Systemic and renal effects of a new angiotensin converting enzyme inhibitor, benazepril, in essential hypertension.

    abstract::Seventeen essential hypertensive patients with normal renal function were treated with a new non-sulphydryl orally active angiotensin converting enzyme (ACE) inhibitor, benazepril, 10 mg given once or twice daily, according to diastolic blood pressure levels, for 6 weeks. In all patients, changes in blood pressure, sy...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199011000-00003

    authors: Valvo E,Casagrande P,Bedogna V,Antiga L,Alberti D,Zamboni M,Perobelli L,Dal Santo F,Maschio G

    更新日期:1990-11-01 00:00:00

  • Renal protective effects of chronic exercise and antihypertensive therapy in hypertensive rats with chronic renal failure.

    abstract:OBJECTIVES:Patients with chronic renal failure are restricted to mild physical activity and tend to a lack of exercise. However, there have been few reports regarding the influence of chronic exercise on the progression of renal disease. Similarly, there are few animal models concerned with the effect of exercise train...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200110000-00024

    authors: Kohzuki M,Kamimoto M,Wu XM,Xu HL,Kawamura T,Mori N,Nagasaka M,Kurosawa H,Minami N,Kanazawa M,Saito T,Yoshida K

    更新日期:2001-10-01 00:00:00

  • A method of quantifying retinal microvascular alterations associated with blood pressure and age.

    abstract:OBJECTIVE:To find an objective, sensitive method for quantifying microvascular alterations associated with level of blood pressure and age. DESIGN:A prospective cross-sectional study. SUBJECTS AND METHODS:Seventy-four previously untreated hypertensive patients, referred to a hospital outpatients department, and 26 no...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:

    authors: Stanton AV,Mullaney P,Mee F,O'Brien ET,O'Malley K

    更新日期:1995-01-01 00:00:00

  • Persistence of antihypertensive efficacy after missed doses: comparison of amlodipine and nifedipine gastrointestinal therapeutic system.

    abstract:OBJECTIVE:In this randomized, double-blind, crossover study, the antihypertensive efficacy of amlodipine and nifedipine gastrointestinal therapeutic system (GITS) was compared following missed doses. Design and methods In a randomized crossover design, 42 patients were randomized to receive amlodipine (5-10 mg) or the ...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004872-200202000-00025

    authors: Elliott HL,Elawad M,Wilkinson R,Singh SP

    更新日期:2002-02-01 00:00:00

  • Effect of acute hyperglycemia on erythrocyte membrane ion transport in offspring of hypertensive parents.

    abstract:OBJECTIVE:Patients with essential hypertension exhibit several red blood cell (RBC) ion transport abnormalities, insulin resistance (IR) and increased risk of developing type 2 diabetes. The aims of this study were to assess RBC ion transport activities under basal conditions and to test the in vivo effect of acute hyp...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200307000-00021

    authors: Suchánková G,Vlasáková Z,Zicha J,Vokurková M,Dobesová Z,Pelikánová T

    更新日期:2003-07-01 00:00:00

  • Supplementation with tetrahydrobiopterin prevents the cardiovascular effects of angiotensin II-induced oxidative and nitrosative stress.

    abstract:OBJECTIVE:The pteridine cofactor tetrahydrobiopterin (BH4) has emerged as a critical determinant of endothelial nitric oxide synthase (eNOS) activity. When BH4 availability is limited, eNOS does not produce nitric oxide (NO) but instead generates superoxide. BH4 may reverse endothelial dysfunction due to cardiovascular...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/01.hjh.0000173520.13976.7d

    authors: Kase H,Hashikabe Y,Uchida K,Nakanishi N,Hattori Y

    更新日期:2005-07-01 00:00:00

  • Genetics of primary aldosteronism.

    abstract::Over the last few years, much progress has been made in understanding the genetic basis of primary aldosteronism. This has led to the diagnosis of the familial forms and has aided the understanding of the basis of sporadic forms of the disease. Such information can be exploited to improve the therapeutic approaches us...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1097/00004872-200404000-00001

    authors: Mulatero P,Morello F,Veglio F

    更新日期:2004-04-01 00:00:00

  • Platelet binding sites and plasma concentration of atrial natriuretic peptide in patients with essential hypertension.

    abstract::The plasma concentration of atrial natriuretic peptide (ANP) and the density and affinity of binding sites for ANP in platelets was investigated in patients with essential hypertension. Severe hypertensives were studied whilst still on medication. All subjects were ambulatory and were investigated after 3 days on a 13...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-198807000-00008

    authors: Schiffrin EL,St-Louis J,Essiambre R

    更新日期:1988-07-01 00:00:00

  • Evaluation of elevated heart rate as a sympathetic nervous system biomarker in essential hypertension.

    abstract:BACKGROUND:There is a need for an easily accessible biomarker of sympathetic nervous activation in essential hypertension, but none exists. Heart rate (HR) has been suggested, but requires validation, now doubly important as an elevated HR in hypertension has emerged as an independent cardiovascular risk factor. METHO...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000002407

    authors: Esler M,Lambert G,Esler D,Ika Sari C,Guo L,Jennings G

    更新日期:2020-08-01 00:00:00

  • Gender differences in artery wall biomechanical properties throughout life.

    abstract::Elevated large artery stiffness and pulse pressure have emerged as important risk factors for cardiovascular disease. The genders differ in large artery biomechanical properties throughout the lifespan with females displaying higher stiffness than males during the prepubertal years and a dramatic increase after menopa...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1097/HJH.0b013e328344da5e

    authors: Rossi P,Francès Y,Kingwell BA,Ahimastos AA

    更新日期:2011-06-01 00:00:00

  • Difference in SBP between arms is a predictor of chronic kidney disease development in the general Korean population.

    abstract:OBJECTIVE:An increased inter-arm SBP difference (IASBPD) is associated with mortality and cardiovascular events, as well as peripheral vascular disease, which is attributed to subclavian stenosis. The aim of the present study was to investigate the association between the IASBPD and incident chronic kidney disease (CKD...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000001931

    authors: Kim GS,Byun YS,Lee HY,Jung IH,Rhee KJ,Kim BO

    更新日期:2019-04-01 00:00:00

  • Left ventricular geometry and endogenous ouabain in a Flemish population.

    abstract:BACKGROUND:Endogenous ouabain, an endogenous digitalis-like steroid, is synthesized in the adrenal glands and possibly in the hypothalamus. In vitro and in vivo, endogenous ouabain triggers growth and proliferation of cardiomyocytes. OBJECTIVE:We therefore investigated the association between left ventricular structur...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e32832e49a8

    authors: Kuznetsova T,Manunta P,Casamassima N,Messaggio E,Jin Y,Thijs L,Richart T,Fagard RH,Bianchi G,Staessen JA

    更新日期:2009-09-01 00:00:00

  • Renal sodium handling in acute and chronic salt loading/depletion protocols: the confounding influence of acute water loading.

    abstract:OBJECTIVES:Renal tubular sodium handling was measured in healthy subjects submitted to acute and chronic salt-repletion/salt-depletion protocols. The goal was to compare the changes in proximal and distal sodium handling induced by the two procedures using the lithium clearance technique. METHODS:In nine subjects, acu...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004872-200018110-00018

    authors: Burnier M,Monod ML,Chioléro A,Maillard M,Nussberger J,Brunner HR

    更新日期:2000-11-01 00:00:00

  • Sodium-lithium countertransport: physiology and function.

    abstract::Current opinions on the relationships between erythrocyte sodium-lithium countertransport kinetics and primary hypertension, hyperlipidaemia and diabetic nephropathy are reviewed. Problems associated with the assay are analysed. Some possible mechanisms that could modify the kinetics of ion exchange are examined. The ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1097/00004872-199816010-00002

    authors: West IC,Rutherford PA,Thomas TH

    更新日期:1998-01-01 00:00:00

  • Prevalence and clinical characteristics of white-coat hypertension based on different definition criteria in untreated and treated patients.

    abstract:BACKGROUND AND AIM:The prevalence and associated risks of white-coat hypertension (WCH) are still a matter of debate. We aimed to assess differences in prevalence and associated conditions of WCH defined on the basis of the normality of all daytime, night-time, and 24-h blood pressure (BP), only daytime, or only 24-h B...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000001493

    authors: de la Sierra A,Vinyoles E,Banegas JR,Segura J,Gorostidi M,de la Cruz JJ,Ruilope LM

    更新日期:2017-12-01 00:00:00