The treatment of obese hypertensive black women: a comparative study of chlorthalidone versus clonidine.

abstract：OBJECTIVE:To gain insight into the mechanisms which contribute to the development of vascular hypertrophy in the spontaneously hypertensive rat (SHR). DESIGN:These experiments were performed under conditions which most closely mimic the growth of smooth muscle in blood vessels, i.e. once cell-cell contact has been ach...

journal_title：Journal of hypertension

authors： Saltis J,Bobik A

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:The platelet GPIIIa plays a pivotal role in platelet aggregation. Previous studies showed an association between the GPIIIa Pl(A1/A2) polymorphism and coronary thrombosis, while there is only contrasting evidence about its role in stroke. We explored the possibility that this polymorphism represents a risk fa...

journal_title：Journal of hypertension

authors： Lanni F,Santulli G,Izzo R,Rubattu S,Zanda B,Volpe M,Iaccarino G,Trimarco B

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To determine the plasma cofactor which is required by diuretics (hydrochlorothiazide, chlorthalidone, indapamide, and furosemide) for direct vasorelaxant effects in vitro. DESIGN:A randomized, double-blind, vehicle-control design was used to avoid experimenter bias. METHODS:We plotted concentration-response...

journal_title：Journal of hypertension

authors： Abrahams Z,Pang MY,Lam EK,Wright JM

更新日期：1998-06-01 00:00:00

abstract：:The haemodynamic effects associated with the onset of hypertension induced by infusion of adrenocorticotrophin (ACTH) were investigated in sheep. Analysis of haemodynamic data collected over 24 h by a computer-based monitoring system revealed that mean arterial pressure (MAP) was significantly increased after 4 h. Car...

journal_title：Journal of hypertension

authors： Spence CD,Brown A,Coghlan JP,Parkes DG,Whitworth JA,Scoggins BA

更新日期：1989-04-01 00:00:00

abstract：:Plasma viscosity and fibrinogen concentrations were measured in 70 diabetics (35 hypertensive and 35 normotensive) and compared with those of 35 age- and sex-matched normotensive healthy subjects in relation to body weight. The body weight, body mass index, blood pressure (systolic and diastolic), mean arterial pressu...

journal_title：Journal of hypertension

authors： Memeh CU

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:To examine in older individuals at high cardiovascular risk whether following a Mediterranean diet decreased the necessity of antihypertensive drugs and modulated their associated cardiovascular risk. METHODS:In the PREvención con DIeta MEDiterránea study, we assessed whether volunteers randomly allocated to...

journal_title：Journal of hypertension

authors： Ribó-Coll M,Lassale C,Sacanella E,Ros E,Toledo E,Sorlí JV,Babio N,Lapetra J,Gómez-Gracia E,Alonso-Gómez ÁM,Fiol M,Serra-Majem L,Pinto X,Castañer O,Díez-Espino J,González JI,Becerra-Tomás N,Cofán M,Díaz-López A,Estru

更新日期：2021-01-25 00:00:00

abstract：OBJECTIVES:(1) To compare urinary guanosine 3',5' cyclic monophosphate (cyclic GMP) excretion between normotensive subjects and essential hypertensive patients; (2) to determine the influence of changes in sodium intake on urinary cyclic GMP excretion in response to the neutral endopeptidase inhibitor candoxatril in es...

journal_title：Journal of hypertension

authors： Sagnella GA,Singer DR,Markandu ND,Buckley MG,MacGregor GA

更新日期：1992-04-01 00:00:00

abstract：:: The aim of the current article is to review the current evidence on the role of morning blood pressure (BP) in the management of hypertension. Morning BP surge had been and will continue to be a hot topic of hypertension research. However, more evidence is needed to prove its clinical usefulness in the management of...

journal_title：Journal of hypertension

authors： Wang JG,Kario K,Park JB,Chen CH

更新日期：2017-08-01 00:00:00

abstract：:We studied 56 patients with essential hypertension to determine whether responses to standardized laboratory mental and physical challenges accurately reflect blood pressure variability during routine daily activities. Four activities were performed in the laboratory: mental arithmetic, a reaction time test, isometric...

journal_title：Journal of hypertension

authors： Floras JS,Hassan MO,Jones JV,Sleight P

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVE:To investigate the association between hypertension and musculoskeletal complaints among men and women selected by a population-based sample. METHODS:A cross-sectional study, with participants selected using a multistage sampling procedure and interviewed at home, was conducted to investigate the association...

journal_title：Journal of hypertension

authors： Kerkhoff AC,Moreira LB,Fuchs FD,Fuchs SC

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:Nephrin, a cytoskeletal protein which localizes to the slit pore of podocytes, may play a role in proteinuria. This study examines the possible relationship between nephrin expression and albuminuria in normotensive and hypertensive diabetic rats. METHODS:Streptozotocin diabetes was induced in both Wistar-Ky...

journal_title：Journal of hypertension

authors： Forbes JM,Bonnet F,Russo LM,Burns WC,Cao Z,Candido R,Kawachi H,Allen TJ,Cooper ME,Jerums G,Osicka TM

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:We studied the vasoconstrictor effects of the thromboxane A2 (TxA2) analogue U46619 in the perfused hind limb of rats under constant flow before and after intravenous injection of irbesartan, an angiotensin II AT1 receptor antagonist, to test whether irbesartan interacts in vivo with the thromboxane A2/prosta...

journal_title：Journal of hypertension

authors： Fukuhara M,Neves LA,Li P,Diz DI,Ferrario CM,Brosnihan KB

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVES:Rapid growth velocity in early life may be a risk factor for obesity, elevated blood pressure, and adverse metabolic markers in childhood, but results are not consistent. We analysed the association between peak growth velocity during the first 2 years of life and blood pressure, fasting glucose and insulin ...

journal_title：Journal of hypertension

authors： Thiering E,Brüske I,Kratzsch J,Hoffmann B,Herbarth O,von Berg A,Schaaf B,Wichmann HE,Heinrich J,LISAplus Study Group.

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:Preeclampsia is associated with an elevated risk of cardiovascular disease later in life. Women with a history of preeclampsia are at risk of developing hypertension as well as ischemic heart disease. Identification of women at the highest risk is important to initiate preventive strategies. We investigated w...

journal_title：Journal of hypertension

authors： Muijsers HEC,Westermann D,Birukov A,van der Heijden OWH,Drost JT,Kräker K,Haase N,Müller DN,Herse F,Maas AHEM,Dechend R,Zeller T,Roeleveld N

更新日期：2020-10-01 00:00:00

abstract：:Interstrain restriction fragment length polymorphism was detected after Southern blot hybridization of spontaneously hypertensive (SHR) and control (WKY) rat DNA digested by Bam HI restrictase with a v-fos probe. The SHR genome was characterized by an additional minor band of 4.0 kb. Other restriction fragment length ...

journal_title：Journal of hypertension

authors： Kotelevtsev YV,Brashishkite DA,Spitkovski DD,Kiselev FL,Postnov YV

更新日期：1988-10-01 00:00:00

abstract：:Left ventricular hypertrophy (LVH), despite its adaptive nature, increases cardiovascular morbidity and mortality. Novel approaches for protection against pathological heart remodelling are presented in this supplement. Melatonin diminishes myocardial fibrosis in rats exposed to continuous light and N-nitro-L-arginine...

journal_title：Journal of hypertension

authors： Simko F,Pechanova O

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:We aimed to investigate whether blood pressure (BP) in the subacute stage of ischemic stroke affects subsequent vascular events after acute ischemic stroke. METHODS:From a prospective stroke registry database, consecutive ischemic stroke patients arriving within 48 h of onset were identified. The mean and S...

journal_title：Journal of hypertension

authors： Kang J,Kim BJ,Yang MH,Jang MS,Han MK,Lee JS,Gorelick PB,Lee J,Bae HJ

更新日期：2019-10-01 00:00:00

abstract：AIM:The aim of this study was to assess the prevalence of ascending aortic dilatation and to evaluate the possible association between proximal aorta dilatation and structural or functional markers of cardiac organ damage in hypertensive patients. BACKGROUND:Dilatation of the sinus of valsalva (SoV) is a common findin...

journal_title：Journal of hypertension

authors： Milan A,Degli Esposti D,Salvetti M,Izzo R,Moreo A,Pucci G,Bruno G,Pareo I,Parini A,Paini A,Laurino FI,Sormani P,Sgariglia R,Avenatti E,De Luca N,Working Group on Heart and Hypertension of the Italian Society of Hypertension

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:Low insulin sensitivity is closely related to both cardiovascular diseases and diabetes development. Still, correlates of insulin sensitivity have mainly been examined in cross-sectional studies. As far as we are aware, the longitudinal stability of insulin sensitivity in young men is largely unknown. We aime...

journal_title：Journal of hypertension

authors： Skårn SN,Flaa A,Kjeldsen SE,Rostrup M,Brunborg C,Reims HM,Fossum E,Høieggen A,Aksnes TA

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on pneumonia hospitalization in patients with stroke history in Taiwan. METHODS:We conducted a case-crossover study using the National Health Insurance Research Database in Taiwan during the period from...

journal_title：Journal of hypertension

authors： Liu CL,Shau WY,Wu CS,Lai MS

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:Cardiac hypertrophy arises as an adaptive response to increased afterload. Studies in knockout mice have shown that catecholamines, but not alpha1-adrenergic receptors, are necessary for such an adaptation to occur. However, whether beta-adrenergic receptors are critical for the development of cardiac hypertr...

journal_title：Journal of hypertension

authors： Palazzesi S,Musumeci M,Catalano L,Patrizio M,Stati T,Michienzi S,Di Certo MG,Mattei E,Vitelli L,Marano G

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVES:Night-time blood pressure (BP) - prognostically more important than circadian BP variability - has not been evaluated for quantitative associations with objective sleep quality in large populations. METHODS:The cross-sectional study measured actigraphic sleep parameters and night-time BP for two nights in 1...

journal_title：Journal of hypertension

authors： Oume M,Obayashi K,Asai Y,Ogura M,Takeuchi K,Tai Y,Kurumatani N,Saeki K

更新日期：2018-03-01 00:00:00

abstract：:Systolic (SBP), diastolic (DBP) and mean [MBP = diastolic + 1/3 (systolic - diastolic)] blood pressures were compared as predictors of all causes of death (ALL) and of deaths from atherosclerotic cardiovascular disease (ACVD) in 2480 men, aged 40-59 years, belonging to three cohorts followed up for 20 years. Both univ...

journal_title：Journal of hypertension

authors： Menotti A,Seccareccia F,Giampaoli S,Giuli B

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:We investigated to what extent anthropometric and lifestyle factors contributed to the classification of Chinese individuals into groups with white-coat, masked and sustained hypertension (HT). METHODS:We measured the office and ambulatory blood pressure (BP) in 694 Chinese enrolled in the JingNing populatio...

journal_title：Journal of hypertension

authors： Wang GL,Li Y,Staessen JA,Lu L,Wang JG

更新日期：2007-12-01 00:00:00

abstract：:Atrial natriuretic peptide (ANP) plays a pivotal role in modulation of vascular function and it is also involved in the pathophysiology of several cardiovascular diseases. We provide an updated overview of the current appraisal of ANP vascular effects in both animal models and humans. We describe the physiological imp...

journal_title：Journal of hypertension

authors： Rubattu S,Calvieri C,Pagliaro B,Volpe M

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To investigate relationships between birth characteristics and blood pressure at age 20 years and to assess whether effects of birth weight on blood pressure are amplified from childhood to adulthood. DESIGN:A longitudinal study of 584 men and women from Adelaide, Australia, examined previously at 8 years an...

journal_title：Journal of hypertension

authors： Moore VM,Cockington RA,Ryan P,Robinson JS

更新日期：1999-07-01 00:00:00

abstract：AIM:To investigate same day repeated measures and diurnal variation of arterial stiffness, cardiac output (CO), stroke volume (SV) and total peripheral resistance (TPR) during the third trimester of normal pregnancy. METHODOLOGY:Pulse wave velocity (PWV) and augmentation index (AIx) were recorded using the Arteriograp...

journal_title：Journal of hypertension

authors： Osman MW,Leone F,Nath M,Khalil A,Webb DR,Robinson TG,Mousa HA

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:To determine the effects of angiotensin II (AII) (1-8) on cytosolic free calcium concentrations in the absence and in the presence of the selective angiotensin subtype 1 (AT1) receptor antagonist losartan and of the selective angiotensin subtype 2-receptor antagonist P-186 in human peripheral blood mononuclea...

journal_title：Journal of hypertension

authors： Lijnen P,Fagard R,Petrov V

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVE:To ascertain the relationships between the kinetic properties of erythrocyte Na+-H+ exchange [maximum kinetic energy (Vmax), Michaelis constant (Km) for internal H+ and Hill's coefficient], Na+-Li+ (Vmax and Km for external Na+), and metabolic parameters in normotensive controls and hypertensive subjects. MA...

journal_title：Journal of hypertension

authors： Semplicini A,Ceolotto G,Felice M,Reato S,Valle R,Gebbin A,Fontebasso A,Serena L,Pessina AC

更新日期：1995-12-01 00:00:00

abstract：:Nitric oxide formed by neuronal nitric oxide synthase (nNOS) in the brain, autonomic inhibitory (nitrergic) nerves, and heart plays important roles in the control of blood pressure. Activation of nitrergic nerves innervating the systemic vasculature elicits vasodilatation, decreases peripheral resistance, and lowers b...

journal_title：Journal of hypertension

authors： Toda N,Ayajiki K,Okamura T

更新日期：2009-10-01 00:00:00