Insulin resistance determines phagocytic nicotinamide adenine dinucleotide phosphate oxidase overactivation in metabolic syndrome patients.

abstract：:Several myosin isoforms are expressed in smooth muscle, based upon both heavy and light chain polymorphisms. These myosin isoenzymes reveal distinct detachment rate constants, thus regulating the responsiveness of the VSMC contractile apparatus to Ca2+, as well as its energetical and mechanical behavior. ...

journal_title：Journal of hypertension

authors： Morano IL

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:To estimate the sensitivity and specificity of self-reported hypertension (HTN) as compared with the clinical diagnosis in epidemiological studies. METHODS:We searched MEDLINE, Embase, Scopus, Web of Science, LILACS, Google Scholar, and ProQuest Dissertations & Theses Global: Health & Medicine databases. In ...

journal_title：Journal of hypertension

authors： Gonçalves VSS,Andrade KRC,Carvalho KMB,Silva MT,Pereira MG,Galvao TF

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:The pregnant spontaneously hypertensive rat (SHR) exhibits a decrease in arterial blood pressure shortly before delivery; however, the mechanisms are unknown. Nitric oxide may be involved. DESIGN:Blood pressure in stroke-prone SHR (SHRSP) and Wistar-Kyoto control rats (WKY) was telemetrically measured. Four ...

journal_title：Journal of hypertension

authors： Gompf H,Luft FC,Morano I

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVES:Lower parental education is associated with higher adolescent blood pressure (BP). We examined the contribution of modifiable risk factors from infancy to adolescence that could potentially explain the link between parental education and SBP and DBP in the offspring. METHODS:In a prospective Chinese birth c...

journal_title：Journal of hypertension

authors： Kwok MK,Schooling CM,Subramanian SV,Leung GM,Kawachi I

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:There are no studies that relate BsmI polymorphism of the vitamin D receptor (VDR) gene and with vitamin D to blood pressure (BP). OBJECTIVE:To analyze if this polymorphism and 25-hydroxyvitamin D levels (25OHD3) influence BP in a population of healthy subjects. DESIGN:Transversal study on healthy populati...

journal_title：Journal of hypertension

authors： Muray S,Parisi E,Cardús A,Craver L,Fernández E

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:Studies of experimental animals show glomerular hypertension to be important in the progression of glomerular disease. We evaluated this connection clinically by examining the relationship between glomerular hemodynamics and histological changes in patients with immunoglobulin (Ig)A nephropathy. METHODS:The ...

journal_title：Journal of hypertension

authors： Konishi Y,Imanishi M,Okamura M,Yoshioka K,Okumura M,Okada N,Tanaka S,Fujii S,Kimura G

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To investigate the interrelationship between arrhythmias provoked by acute pressure changes, and the presence of left ventricular hypertrophy and electrolyte imbalances. DESIGN:An isolated working rat heart model was used in a prospective comparison of the effects of acute pressure changes in hypertensive an...

journal_title：Journal of hypertension

authors： James MA,Jones JV

更新日期：1992-02-01 00:00:00

abstract：OBJECTIVE:Genome-wide association studies have linked variants of fat mass and obesity-associated protein (FTO) to obesity. However, the molecular function of FTO remains unclear. In this study, we sought to investigate the potential effects of FTO in modulating cholesterol deposition in macrophage foam cells, as well ...

journal_title：Journal of hypertension

authors： Mo C,Yang M,Han X,Li J,Gao G,Tai H,Huang N,Xiao H

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:Hypertension affects cerebrovascular autoregulation and increases the risk of cerebrovascular events and dementia. Notably, it is associated with cerebrovascular remodeling and lower resting cerebral blood flow (CBF). We wanted to determine, using arterial spin-labeling-MRI, the impact of a head-down tilt (HD...

journal_title：Journal of hypertension

authors： Seiller I,Pavilla A,Ognard J,Ozier-Lafontaine N,Colombani S,Cepeda Ibarra Y,Mejdoubi M

更新日期：2020-12-09 00:00:00

abstract：OBJECTIVE:To investigate the role of an activated endothelin system in the renal dysfunction observed in chronic heart failure after myocardial infarction. METHODS:In rats with heart failure after myocardial infarction and in sham-operated animals (Sham), we investigated the effect on renal function of long-term oral ...

journal_title：Journal of hypertension

authors： Bauersachs J,Braun C,Fraccarollo D,Widder J,Ertl G,Schilling L,Kirchengast M,Rohmeiss P

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:Adenosine dilates rabbit renal arteries by an endothelium-dependent, nitric oxide (NO)- and prostaglandin-independent mechanism. The aim was to identify the responsible P1-purinoceptor subtype and to investigate the involvement of K+-channels. METHODS:Rabbit renal arteries were perfused with medium containin...

journal_title：Journal of hypertension

authors： Rump LC,Jabbari-T J,von Kügelgen I,Oberhauser V

更新日期：1999-12-01 00:00:00

abstract：:A10 vascular smooth muscle cells were placed in a flow chamber and exposed to the circulation of foetal calf serum at different rates and pressures. Under unidirectional laminar flow, physiological flow rates and pressures had almost no effect on internal sodium content. Indeed, pressure values greater than 150 mmHg w...

journal_title：Journal of hypertension

authors： Rosati C,Garay R

更新日期：1991-11-01 00:00:00

abstract：:: Altered blood pressure (BP) is a common phenomenon in acute ischemic stroke (AIS), with high BP being the most frequent scenario. The pathophysiology of BP changes in AIS is complex and only partially understood. The available evidence indicates that extremely high BP during AIS is associated with a poor outcome. Im...

journal_title：Journal of hypertension

authors： Gąsecki D,Coca A,Cunha P,Hering D,Manios E,Lovic D,Zaninelli A,Sierra C,Kwarciany M,Narkiewicz K,Karaszewski B

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Arterial stiffness is an independent predictor of cardiovascular events and mortality in hypertensive patients. The influence of different antihypertensive drug classes on improving arterial stiffness beyond blood pressure reduction is not widely available. We aimed to determine whether the artery stiffness ...

journal_title：Journal of hypertension

authors： Ong KT,Delerme S,Pannier B,Safar ME,Benetos A,Laurent S,Boutouyrie P,investigators.

更新日期：2011-06-01 00:00:00

abstract：AIMS:Baroreflex activation therapy (BAT) has recently been shown to reduce muscle sympathetic nerve activity and hospitalization rate while improving clinical variables through 6 months of therapy in patients with heart failure and reduced ejection fraction (HFrEF). The objective of the present study is to extend the i...

journal_title：Journal of hypertension

authors： Gronda E,Seravalle G,Trevano FQ,Costantino G,Casini A,Alsheraei A,Lovett EG,Vanoli E,Mancia G,Grassi G

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:To determine whether the decision to treat uncomplicated mild hypertension with drugs, in accordance with the World Health Organization - International Society of Hypertension (WHO/ISH) guidelines based on a series of blood pressure (BP) measurements over 6 months, resulted in the treatment of patients at hig...

journal_title：Journal of hypertension

authors： Abergel E,Chatellier G,Battaglia C,Menard J

更新日期：1999-06-01 00:00:00

abstract：:Plasma viscosity and fibrinogen concentrations were measured in 70 diabetics (35 hypertensive and 35 normotensive) and compared with those of 35 age- and sex-matched normotensive healthy subjects in relation to body weight. The body weight, body mass index, blood pressure (systolic and diastolic), mean arterial pressu...

journal_title：Journal of hypertension

authors： Memeh CU

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:Construction of prognostically relevant endpoints for clinical trials in hypertension has increasingly included coronary revascularization with myocardial infarction (MI) as manifestations of coronary artery disease. However, whether coronary revascularization and MI predict other cardiovascular events simila...

journal_title：Journal of hypertension

authors： Cicala S,de Simone G,Gerdts E,Dahlöf B,Lindholm LH,Kjeldsen SE,Devereux RB

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:During the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial, patients with hypertension who received amlodipine had similar cardiovascular risks as those who received candesartan. We conducted a post-trial study, the Candesartan Antihypertensive Survival Evaluation in Japan 10-year fol...

journal_title：Journal of hypertension

authors： Liu J,Yasuno S,Oba K,Konda M,Ichihara C,Kitao H,Kuwabara Y,Ueshima K

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Secondary prevention of stroke with antihypertensive drugs is now standard practice, but it is unclear how soon after a cerebrovascular event antihypertensive therapy should be initiated or re-started. Due to impaired cerebral autoregulation, changes in systemic blood pressure may be reflected in cerebral pe...

journal_title：Journal of hypertension

authors： Nazir FS,Overell JR,Bolster A,Hilditch TE,Reid JL,Lees KR

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:High blood pressure is common in acute stroke and is associated independently with poor outcome. Lowering blood pressure might improve outcome, provided it does not reduce cerebral blood flow in the presence of dysfunctional cerebral autoregulation. METHODS:We performed a systematic review of clinical contro...

journal_title：Journal of hypertension

authors： Sare GM,Gray LJ,Bath PM

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:The present study aimed to characterize the influence of salt intake on the gene expression of the kidney specific chloride channels CLC-K1 and CLC-K2 in the kidneys of salt-resistant and salt-sensitive Dahl rats. DESIGN:For this purpose Dahl salt-resistant (Dahl-R) and Dahl salt-sensitive rats (Dahl-S) were...

journal_title：Journal of hypertension

authors： Castrop H,Krämer BK,Riegger GA,Kurtz A,Wolf K

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:We hypothesized that downregulation of the antioxidant thioredoxin system contributes to oxidative stress in angiotensin II-induced hypertension. As oestrogen may protect against oxidative stress, we also evaluated whether the thioredoxin system, particularly in the heart, is differentially regulated between ...

journal_title：Journal of hypertension

authors： Ebrahimian T,He Y,Schiffrin EL,Touyz RM

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVES:It is estimated that there are more than 16 million adults with drug-resistant hypertension in China. Nevertheless, the prevalence of and risk factors for primary aldosteronism, a highly curable condition among adults with drug-resistant hypertension, has not been fully investigated. METHODS:Between January...

journal_title：Journal of hypertension

authors： Sang X,Jiang Y,Wang W,Yan L,Zhao J,Peng Y,Gu W,Chen G,Liu W,Ning G

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:Reflection of the finger pulse wave form is a valid measure of arterial stiffness, which may be continuously assessed during sleep. We investigated the relationships between sleep, sleep-disordered breathing, hypertension, and pulse propagation time (PPT) in patients with suspected sleep apnea. METHODS:The ...

journal_title：Journal of hypertension

authors： Svedmyr S,Zou D,Sommermeyer D,Ficker JH,Randerath W,Fietze I,Sanner B,Hedner J,Grote L

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:Dietary sodium and potassium intakes are factors known to influence blood pressure (BP) through different pathways. These mechanisms likely result in differential effects on parameters characterizing BP. The aim of the study was to evaluate relationships between both sodium and potassium intake and all BP par...

journal_title：Journal of hypertension

authors： Buyck JF,Blacher J,Kesse-Guyot E,Castetbon K,Galan P,Safar M,Hercberg S,Czernichow S

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:We investigated the contribution of reduced nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase-dependent reactive oxygen species (ROS) generation to the pathogenesis of diastolic heart failure (DHF) in Dahl salt-sensitive (DS) hypertensive rats, with the aim of testing our hypothesis that the cardiop...

journal_title：Journal of hypertension

authors： Guo P,Nishiyama A,Rahman M,Nagai Y,Noma T,Namba T,Ishizawa M,Murakami K,Miyatake A,Kimura S,Mizushige K,Abe Y,Ohmori K,Kohno M

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:We previously showed that young transgenic mice overexpressing preproendothelin-1 specifically in endothelial cells had hypertrophic remodeling, endothelial dysfunction, increased vascular NADPH oxidase activity, and inflammation in mesenteric small arteries without blood pressure (BP) elevation compared to ...

journal_title：Journal of hypertension

authors： Amiri F,Ko EA,Javeshghani D,Reudelhuber TL,Schiffrin EL

更新日期：2010-06-01 00:00:00

abstract：:We have demonstrated high concentrations of inactive renin in mouse amniotic fluid compared with mouse plasma and other organs. Its molecular weight was similar to that of prorenin from the mouse submaxillary gland (42 000 daltons). The activated renin had a Km value of 1.48 greater than M which is identical to that o...

journal_title：Journal of hypertension

authors： Jacobsen J,Poulsen K

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVE:It is not well known which exercise intensity is needed to obtain blood pressure reductions in response to endurance training. We therefore compared the effect of training at lower and higher intensity on blood pressure, and, in addition on other cardiovascular risk factors, in at least 55-year-old sedentary ...

journal_title：Journal of hypertension

authors： Cornelissen VA,Arnout J,Holvoet P,Fagard RH

更新日期：2009-04-01 00:00:00