Genetic heterogeneity of familial hyperkalaemic hypertension.

abstract：OBJECTIVE:To evaluate endothelium-dependent vascular function in obstructive sleep apnoea patients. DESIGN AND METHODS:Forearm blood flow and vascular resistance were studied in eight normotensives and eight obstructive sleep apnoea patients and also in eight normotensive and eight hypertensive controls after graded b...

journal_title：Journal of hypertension

authors： Carlson JT,Rångemark C,Hedner JA

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:To gain insight into the mechanisms which contribute to the development of vascular hypertrophy in the spontaneously hypertensive rat (SHR). DESIGN:These experiments were performed under conditions which most closely mimic the growth of smooth muscle in blood vessels, i.e. once cell-cell contact has been ach...

journal_title：Journal of hypertension

authors： Saltis J,Bobik A

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine the optimal schedule for home blood pressure (HBP) measurement based on a clinical approach. METHODS:Four hundred and sixty-four participants underwent HBP measurement for 7 days (duplicate measurements in the morning and in the evening), ambulatory blood pressure (ABP)...

journal_title：Journal of hypertension

authors： Johansson JK,Niiranen TJ,Puukka PJ,Jula AM

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:We examined the relation between cardiovascular reactivity (the response of the cardiovascular system to psychological stress) and the severity and progression of carotid atherosclerosis. METHODS:Using duplex ultrasonography, we measured the change in the area of all detectable plaques in the extracranial c...

journal_title：Journal of hypertension

authors： Barnett PA,Spence JD,Manuck SB,Jennings JR

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVES:Recent studies in homogenized hearts suggest that chymase rather than angiotensin converting enzyme (ACE) is responsible for cardiac angiotensin I to angiotensin II conversion. We investigated in intact rat hearts whether (i) enzymes other than ACE contribute to angiotensin I to angiotensin II conversion and...

journal_title：Journal of hypertension

authors： de Lannoy LM,Schuijt MP,Saxena PR,Schalekamp MA,Danser AH

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:We aimed to investigate associations of childhood pulse pressure (PP) and change in PP status with adult subclinical vascular damage. METHODS:Data were obtained from a population-based cohort of children aged 6-18 years started in 1987. The study constituted 1254 participants who were followed up in 2010-201...

journal_title：Journal of hypertension

authors： Hou D,Yan Y,Liu J,Zhao X,Cheng H,Mi J

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:The present study aimed to characterize the influence of salt intake on the gene expression of the kidney specific chloride channels CLC-K1 and CLC-K2 in the kidneys of salt-resistant and salt-sensitive Dahl rats. DESIGN:For this purpose Dahl salt-resistant (Dahl-R) and Dahl salt-sensitive rats (Dahl-S) were...

journal_title：Journal of hypertension

authors： Castrop H,Krämer BK,Riegger GA,Kurtz A,Wolf K

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Constitutional hypotension (CHT) is defined as a SBP below 105 mmHg. As autonomic-related symptoms are frequently reported in CHT, these symptoms suggest that the cardiovascular autonomic control is perturbed in individuals with CHT. METHODS:We investigated the autonomic cardiovascular control of 15 women w...

journal_title：Journal of hypertension

authors： Jacob G,Barbic F,Glago M,Dipaola F,Porta A,Furlan R

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVES:Rapid growth velocity in early life may be a risk factor for obesity, elevated blood pressure, and adverse metabolic markers in childhood, but results are not consistent. We analysed the association between peak growth velocity during the first 2 years of life and blood pressure, fasting glucose and insulin ...

journal_title：Journal of hypertension

authors： Thiering E,Brüske I,Kratzsch J,Hoffmann B,Herbarth O,von Berg A,Schaaf B,Wichmann HE,Heinrich J,LISAplus Study Group.

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:(1) To compare urinary guanosine 3',5' cyclic monophosphate (cyclic GMP) excretion between normotensive subjects and essential hypertensive patients; (2) to determine the influence of changes in sodium intake on urinary cyclic GMP excretion in response to the neutral endopeptidase inhibitor candoxatril in es...

journal_title：Journal of hypertension

authors： Sagnella GA,Singer DR,Markandu ND,Buckley MG,MacGregor GA

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:Microalbuminuria (MA) is a marker of adverse outcome in hypertension. The aim of this study was to investigate the association of MA with cardiovascular risk factors and glomerular hyperfiltration in the early stage of hypertension and to assess its predictive value for the development of sustained hypertensi...

journal_title：Journal of hypertension

authors： Palatini P,Mormino P,Mos L,Mazzer A,Dorigatti F,Zanata G,Longo D,Garbelotto R,De Toni R,Graniero G,Pessina AC,HARVEST Study Group.

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Despite data from animal models and observational studies that are generally supportive for the soy/isoflavones lowering blood pressure (BP) and improving vascular function, the current findings from clinical trials are still inconclusive. OBJECTIVES:To examine whether soy protein with isoflavones or isofla...

journal_title：Journal of hypertension

authors： Liu ZM,Ho SC,Chen YM,Woo J

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To examine in a population with a high prevalence of hypertension, the association between six cardiovascular polymorphisms, arterial stiffness and medication use. METHODS:In this cross-sectional study (Hypertension: Interaction and Prevalence of POlymorphisms related to Cardiovascular Risk and the Associati...

journal_title：Journal of hypertension

authors： Plat AW,Stoffers HE,de Leeuw PW,van Schayck CP,Soomers FL,Kester AD,Aretz K,Kroon AA

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Urocortin 1 (Ucn1) and the sympathetic nervous system both participate in cardiac and circulatory regulation, but little is known about their possible interactions. METHODS:We report the effects of Ucn1 on the cardiac sympathetic nerve activity (CSNA), haemodynamics and plasma catecholamines in normal sheep...

journal_title：Journal of hypertension

authors： Charles CJ,Jardine DL,Nicholls MG,Rademaker MT,Richards AM

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Cross-sectional evidence indicates that eating frequency correlates with blood pressure, hypertension, and related target organ damage. The aim of the present study was to prospectively assess eating frequency as a predictor of arteriosclerosis progression and new onset hypertension over a follow-up period o...

journal_title：Journal of hypertension

authors： Karatzi K,Georgiopoulos G,Yannakoulia M,Efthimiou E,Voidonikola P,Mitrakou A,Manios E,Alevizaki M,Papamichael C,Stamatelopoulos K

更新日期：2016-03-01 00:00:00

abstract：:: We aimed to combine evidence from all heart failure trials that have investigated the effects of drugs with blood pressure (BP)-lowering properties to assess the extent to which such drugs reduce BP in heart failure, the association between the net change in BP between treatment arms and cause-specific outcomes and ...

journal_title：Journal of hypertension

authors： Pinho-Gomes AC,Azevedo L,Bidel Z,Nazarzadeh M,Canoy D,Copland E,Salam A,Rodgers A,Kotecha D,Rahimi K

更新日期：2019-09-01 00:00:00

abstract：:The postulated antihypertensive effect of dietary fish oil and the influence of dietary sodium on this effect were evaluated in young stroke-prone spontaneously hypertensive rats (SHRSP) by direct intra-arterial measurement of blood pressure. Weaning rats were fed synthetic diets containing olive oil or eicosapentaeno...

journal_title：Journal of hypertension

authors： Howe PR,Lungershausen YK,Rogers PF,Gerkens JF,Head RJ,Smith RM

更新日期：1991-07-01 00:00:00

abstract：OBJECTIVES:Local atrial tissue angiotensin II (AngII) level is elevated in atrial fibrillation (AF), but the mechanism is unknown. We hypothesized that atrial myocytes express all components of the renin-angiotensin system (RAS) and investigated whether rapid depolarization alone is sufficient to increase paracrine Ang...

journal_title：Journal of hypertension

authors： Tsai CT,Lai LP,Hwang JJ,Chen WP,Chiang FT,Hsu KL,Tseng CD,Tseng YZ,Lin JL

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To investigate predictors of left ventricular mass corrected for height2.7 (LVMI) and left ventricular hypertrophy in patients who were found to be normotensive with both office and 24-h ambulatory blood pressure (BP) measurements. METHODS:A total of 805 consecutive patients were analyzed. All patients under...

journal_title：Journal of hypertension

authors： Kotsis V,Stabouli S,Toumanidis S,Tsivgoulis G,Rizos Z,Trakateli C,Zakopoulos N,Sion M

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:In some patients with aortic stenosis left-ventricular hypertrophy exceeds what is needed to sustain the hemodynamic load imposed by the aortic stenosis, a condition named inappropriately high left-ventricular mass (iLVM). Although iLVM is associated with increased mortality after aortic valve replacement, pr...

journal_title：Journal of hypertension

authors： Cioffi G,de Simone G,Cramariuc D,Mureddu GF,Gerdts E

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:Traditional cardiovascular risk factors do not fully account for ethnic differences in cardiovascular disease. We tested if arterial function indices, particularly augmentation index (AIx), and their determinants from childhood could underlie such ethnic variability among young British adults in the 'DASH' lo...

journal_title：Journal of hypertension

authors： Faconti L,Silva MJ,Molaodi OR,Enayat ZE,Cassidy A,Karamanos A,Nanino E,Read UM,Dall P,Stansfield B,Harding S,Cruickshank KJ

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:There is a need for an easily accessible biomarker of sympathetic nervous activation in essential hypertension, but none exists. Heart rate (HR) has been suggested, but requires validation, now doubly important as an elevated HR in hypertension has emerged as an independent cardiovascular risk factor. METHO...

journal_title：Journal of hypertension

authors： Esler M,Lambert G,Esler D,Ika Sari C,Guo L,Jennings G

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVES:Several studies have shown lower carotid-femoral pulse wave velocity (cfPWV) levels in women compared to men, a difference that could partially explain the increased longevity in women. However, these studies have been performed in industrial countries while few data are available in emerging populations. We...

journal_title：Journal of hypertension

authors： Temmar M,Watfa G,Joly L,Kearney-Schwartz A,Youcef M,Bensalah S,Mustapha Y,Salvi P,Gautier S,Safar M,Labat C,Benetos A

更新日期：2013-11-01 00:00:00

abstract：:The activity of renal Na-K-ATPase was compared in hypertension-prone (SBH) and hypertension-resistant (SBN) Sabra rats on regular sodium intake and 2-3 weeks after a high sodium diet. ATPase activity was determined in single nephron segments by a micromethod. The activity profile was found to be similar in the two sub...

journal_title：Journal of hypertension

authors： Doucet A,Mekler J,el Mernissi G,Ben-Ishay D

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVE:Dietary sodium and potassium intakes are factors known to influence blood pressure (BP) through different pathways. These mechanisms likely result in differential effects on parameters characterizing BP. The aim of the study was to evaluate relationships between both sodium and potassium intake and all BP par...

journal_title：Journal of hypertension

authors： Buyck JF,Blacher J,Kesse-Guyot E,Castetbon K,Galan P,Safar M,Hercberg S,Czernichow S

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVES:The role of circadian rhythm of energy and macronutrient intake in influencing cardiometabolic risk factors is increasingly recognized. However, little is known of the association between time of energy intake and blood pressure. We examined the association between time-of-day of energy intake and subsequent...

journal_title：Journal of hypertension

authors： Almoosawi S,Prynne CJ,Hardy R,Stephen AM

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the prognostic significance of cardiovascular risk factors including 24-h ambulatory blood pressure level and rhythm for all-cause mortality in type 2 diabetic patients. METHODS:In a prospective observational study, 104 patients with type 2 diabetes were followed: 51 patients with diabetic nephro...

journal_title：Journal of hypertension

authors： Astrup AS,Nielsen FS,Rossing P,Ali S,Kastrup J,Smidt UM,Parving HH

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVES:Genetic variants that influence large conductance calcium-activated potassium channel's function may alter arterial function and contribute to the known heritability of arterial stiffness and blood pressure. The beta1-subunit (KCNMB1) of the large conductance calcium-activated potassium channel includes two ...

journal_title：Journal of hypertension

authors： Kelley-Hedgepeth A,Peter I,Montefusco MC,Levy D,Benjamin EJ,Vasan RS,Mendelsohn ME,Housman D,Huggins GS,Mitchell GF

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Uncontrolled hypertension notwithstanding the use of at least three drugs or hypertension controlled with at least four drugs, the widely accepted definition of treatment-resistant hypertension (TRH), is considered as a common problem in the hemodialysis population. However, to date there is no estimate of t...

journal_title：Journal of hypertension

authors： Mallamaci F,Torino C,Sarafidis P,Ekart R,Loutradis C,Siamopoulos K,Del Giudice A,Aucella F,Morosetti M,Raptis V,Bikos A,Papagianni A,Balafa O,Pappas E,Tripepi R,Marino C,Tripepi G,Ferro C,Malyszko J,Dekker FW,Jage

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To investigate the role of angiotensin II in the pathogenesis of hyperinsulinemia-induced hypertension in rats. MATERIALS AND METHODS:Chronic hyperinsulinemia was achieved by infusing insulin (3 mU/kg per min) subcutaneously by an osmotic minipump for 6 weeks. An angiotensin converting enzyme inhibitor (fosi...

journal_title：Journal of hypertension

authors： Fang TC,Huang WC

更新日期：1998-12-01 00:00:00