Time-of-day of energy intake: association with hypertension and blood pressure 10 years later in the 1946 British Birth Cohort.

Abstract:

OBJECTIVES:The role of circadian rhythm of energy and macronutrient intake in influencing cardiometabolic risk factors is increasingly recognized. However, little is known of the association between time of energy intake and blood pressure. We examined the association between time-of-day of energy intake and subsequent hypertension and change in blood pressure. METHODS:The analysis included 517 men and 635 women from the 1946 British birth cohort. Diet was assessed using 5-day estimated diaries. Diaries were divided into seven meal slots: breakfast, mid-morning, lunch, mid-afternoon, dinner, late evening and extras. Time-of-day of energy intake at age 43 years was related to hypertension prevalence at 43 years and incidence at age 53 years and 10-year changes in SBP and DBP using logistic regression and censored regression controlling for medication use. RESULTS:Cohort members in the highest quintile of energy intake at breakfast at age 43 years had 30% lower odds of hypertension prevalence compared with those in the lowest. Cohort members in the highest quintile of energy intake at late evening had higher odds of incident hypertension at age 53 years [odds ratio = 1.55; 95% confidence interval (CI) 0.93-2.61; P for linear trend = 0.052]. Compared to the lowest quintile, the highest quintile of energy intake late in the evening was related to a greater rise in SBP (β = 5.09; 95% CI 1.25-8.93) and DBP (43-53 years) (β = 2.08; 95%CI 0.27-5.32). CONCLUSION:Higher energy intake at breakfast is associated with lower hypertension prevalence. Greater energy intake late in the evening is associated with higher hypertension prevalence, incidence and greater increases in blood pressure.

journal_name

J Hypertens

journal_title

Journal of hypertension

authors

Almoosawi S,Prynne CJ,Hardy R,Stephen AM

doi

10.1097/HJH.0b013e32835ecc06

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

882-92

issue

5

eissn

0263-6352

issn

1473-5598

journal_volume

31

pub_type

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