Abstract:
:Glutathione S-transferase activity increased in rats with acute pancreatitis: 2.2 times on day 2, 2-fold on day 4, and 1.5 times on day 10. Inducers of microsomal enzymes aroclor 1254 and phenobarbital notably inhibited glutathione S-transferase activity in animals with experimental pancreatitis on days 2-4 of the disease (3.1-2.5 times in comparison with sham-operated induced animals). Hence, the activity of enzymes of phase II of liver xenobiotic metabolism is altered in acute pancreatitis.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Prokop'eva NV,Gulyaeva LFdoi
10.1007/BF02439801subject
Has Abstractpub_date
2000-05-01 00:00:00pages
458-9issue
5eissn
0007-4888issn
1573-8221journal_volume
129pub_type
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