Changes in the seroepidemiology of hepatitis B infection in Catalonia 1989-1996.

Abstract:

:The objective of this study was to investigate the prevalence of hepatitis B markers in a representative sample of 2142 subjects in Catalonia, Spain, and to compare it with previous studies. Multiple logistical regression analysis was carried out to determine variables associated with the markers studied. The prevalence of anti-HBc and HBsAg was 9.1% and 1.2%, respectively. Male gender, urban habitat, birth place outside Catalonia and lower social class were associated with the presence of anti-HBc. Carrier status was only associated with male gender. Between 1989 and 1996 there was a decrease of 46% in the prevalence of serum HBV markers mainly in the 25-44 (P<0.0001) and 35-64 year (P=0.0002) age groups, in those born in Catalonia (P=0.003) and in those in the higher social classes (P<0.0001). These decreases can be explained by the improved socioeconomic conditions and, partially, by the routine pre-adolescent and risk group programmes of immunization.

journal_name

Vaccine

journal_title

Vaccine

authors

Domínguez A,Bruguera M,Vidal J,Plans P,Salleras L

doi

10.1016/s0264-410x(00)00028-1

subject

Has Abstract

pub_date

2000-05-08 00:00:00

pages

2345-50

issue

22

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(00)00028-1

journal_volume

18

pub_type

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