Abstract：
:HIV-infected children (N=243), >or=5 to <18 years old, receiving stable antiretroviral therapy, were stratified by immunologic status and randomly assigned to receive intranasal live attenuated influenza vaccine (LAIV) or intramuscular trivalent inactivated influenza vaccine (TIV). The safety profile after LAIV or TIV closely resembled the previously reported tolerability to these vaccines in children without HIV infection. Post-vaccination hemagglutination inhibition (HAI) antibody responses and shedding of LAIV virus were also similar, regardless of immunological stratum, to antibody responses and shedding previously reported for children without HIV infection. LAIV should be further evaluated for a role in immunizing HIV-infected children.
journal_name
Vaccinejournal_title
Vaccineauthors
Levin MJ,Song LY,Fenton T,Nachman S,Patterson J,Walker R,Kemble G,Allende M,Hultquist M,Yi T,Nowak B,Weinberg Adoi
10.1016/j.vaccine.2008.05.054subject
Has Abstractpub_date
2008-08-05 00:00:00pages
4210-7issue
33eissn
0264-410Xissn
1873-2518pii
S0264-410X(08)00645-2journal_volume
26pub_type
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