Protective immunity against herpes simplex virus generated by DNA vaccination compared to natural infection.

abstract：:Although vaccination against Streptococcus pneumoniae (S. pneumoniae) and Haemophilus influenzae type b (Hib) is recommended for immunocompromised patients, such as patients with B-cell chronic lymphocytic leukaemia (B-CLL), its protective effect is questionable. We studied antibody responses to pneumococcal polysacch...

journal_title：Vaccine

authors： Hartkamp A,Mulder AH,Rijkers GT,van Velzen-Blad H,Biesma DH

更新日期：2001-02-08 00:00:00

abstract：:Passive immunization of mice with a monoclonal IgE antibody to Schistosoma japonicum (SJ18 epsilon. 1) induces significant protection to a challenge infection and the target molecule of SJ18 epsilon. 1 is paramyosin. In the present study, we demonstrate the B cell epitope of paramyosin recognized by SJ18 epsilon. 1 by...

journal_title：Vaccine

authors： Nara T,Tanabe K,Mahakunkijcharoen Y,Osada Y,Matsumoto N,Kita K,Kojima S

更新日期：1997-01-01 00:00:00

abstract：:Virus-like particles (VLP) are inert, empty capsids of viruses, which contain no DNA/RNA from the virus itself. However they retain the structure of a virus and they can be engineered to have antigens attached. We have constructed VLP, derived from Rabbit hemorrhagic disease virus, and shown they are highly immunogeni...

journal_title：Vaccine

authors： Young SL,Wilson M,Wilson S,Beagley KW,Ward V,Baird MA

更新日期：2006-06-29 00:00:00

abstract：:The practicalities when applying the ICH GCPs (International Conference on Harmonization 1996 Good Clinical Practices [EU, MHLW, FDA. International Conference on Harmonization Guideline for Good Clinical Practice; 1997] in less developed countries (ldcs) are seldom discussed and we found no guidelines as how to "adapt...

journal_title：Vaccine

authors： Acosta CJ,Galindo CM,Ochiai RL,Danovaro-Holliday MC,Laure-Page A,Thiem VD,Jin Y,Khan MI,Sahito SM,Hamza HB,Park JK,Lee H,Bock H,Elyazeed RA,Albert MJ,Ascaso C,Robles TQ,Ali M,Ngai P,Puri MK,Koo YM,Agtini MD,So

更新日期：2007-04-12 00:00:00

abstract：:Confidence in vaccine safety is critical to national immunization strategies and to global public health. To meet the Millenium Development Goals, and buoyed by the success of new vaccines produced in developing countries, the World Health Organization has been developing a strategy to establish a global system for ef...

journal_title：Vaccine

authors： Graham JE,Borda-Rodriguez A,Huzair F,Zinck E

更新日期：2012-07-13 00:00:00

abstract：:We have demonstrated that the fibrinogen-albumin-IgG receptor of group C streptococci (FAI) targets B-cells in vivo. We exploited the targeting properties of FAI to improve the immune responses stimulated by soluble antigens administered by the mucosal route. Enhanced systemic and mucosal immune responses were observe...

journal_title：Vaccine

authors： Schulze K,Goldmann O,Toppel A,Medina E,Guzmán CA

更新日期：2005-02-03 00:00:00

abstract：:A gene encoding the mature Escherichia coli heat-labile enterotoxin B subunit (LTB) was introduced in a vector pNU212 and expressed at high levels in Bacillus brevis HPD31. The maximum amount of recombinant LTB (rLTB) secreted into the modified 5PY medium containing erythromycin was about 350 mg l(-1) when cultivated ...

journal_title：Vaccine

authors： Kozuka S,Yasuda Y,Isaka M,Masaki N,Taniguchi T,Matano K,Moriyama A,Ohkuma K,Goto N,Udaka S,Tochikubo K

更新日期：2000-03-06 00:00:00

abstract：INTRODUCTION:The present study summarizes evidences of the impact that varicella vaccination (VV) introduction and coverage can have on varicella attributable hospitalization rates. METHODS:A retrospective observational study was carried out by considering hospital discharge records and VV coverage at 24 months collec...

journal_title：Vaccine

authors： Amodio E,Casuccio A,Tramuto F,Costantino C,Marrella A,Maida CM,Vitale F,Restivo V

更新日期：2020-07-31 00:00:00

abstract：:The objective of this study was to evaluate the validity of information reported by the elderly on 23-valent pneumococcal polysaccharide vaccine (23vPPV) vaccination status. A cross-sectional, observational study was carried out in patients aged >or=65 years admitted to five Spanish hospitals. Data on 23vPPV vaccinati...

journal_title：Vaccine

authors： Bayas JM,Izquierdo C,Ruiz L,Sintes X,Sousa D,Celorrio JM,Varona W,Carratalà J,Nebot M,Batalla J,Sugrañes S,Manzur A,Terren A,García C,Clemente E,Rivera S,Justo I,Arévalo A,Salleras L,Domínguez A

更新日期：2009-07-23 00:00:00

abstract：:Development of effective new mucosal vaccine adjuvants has become a priority with the increase in emerging viral and bacterial pathogens. We previously reported that cationic liposomes complexed with non-coding plasmid DNA (CLDC) were effective parenteral vaccine adjuvants. However, little is known regarding the abili...

journal_title：Vaccine

authors： Henderson A,Propst K,Kedl R,Dow S

更新日期：2011-07-18 00:00:00

abstract：:Lyme disease (LD) accounts for over 70% of tick-borne disease reported in the United States. The disease in humans is characterized by skin rash, arthritis, cardiac and neurological signs. Vaccination is the most efficient preventive measure that could be taken to reduce the incidence of the LD worldwide; however, at ...

journal_title：Vaccine

authors： Hassan WS,Giaretta PR,Rech R,Ollivault-Shiflett M,Esteve-Gasent MD

更新日期：2019-09-03 00:00:00

abstract：:The level of antibody production induced by a vaccine involves a variety of host factors. One of these, insulin-like growth factor-1 (IGF-1), plays an important role in lymphocyte maturation and antibody expression. Here, we investigated the role of macrophage-derived IGF-1 in the induction of influenza vaccine-specif...

journal_title：Vaccine

authors： Yoon IS,Park H,Kwak HW,Woo Jung Y,Nam JH

更新日期：2017-08-24 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Parents' attitudes toward MMR vaccine and measles, mumps and rubella infections relate to their child's MMR status, therefore improving these attitudes is central to improving current suboptimal MMR uptake. However, no study has yet combined evidence-based, comprehensive and psychometrically va...

journal_title：Vaccine

authors： Brown KF,Shanley R,Cowley NA,van Wijgerden J,Toff P,Falconer M,Ramsay M,Hudson MJ,Green J,Vincent CA,Kroll JS,Fraser G,Sevdalis N

更新日期：2011-02-11 00:00:00

abstract：:The aims of this project were: (1) to determine the extent to which infant hepatitis B immunisation is preventing chronic hepatitis B infection in children living in a sample of Pacific Island countries; and (2) to identify factors associated with the successful prevention of hepatitis B infection in these populations...

journal_title：Vaccine

authors： Wilson N,Ruff TA,Rana BJ,Leydon J,Locarnini S

更新日期：2000-07-01 00:00:00

abstract：:The objectives of this research were to evaluate the risk of prolonged testicular infection as a consequence of vaccination of peri-pubertal bulls with a modified-live, noncytopathic strain of BVDV and to assess vaccine efficacy in preventing prolonged testicular infections after a subsequent acute infection. Seronega...

journal_title：Vaccine

authors： Givens MD,Riddell KP,Walz PH,Rhoades J,Harland R,Zhang Y,Galik PK,Brodersen BW,Cochran AM,Brock KV,Carson RL,Stringfellow DA

更新日期：2007-01-15 00:00:00

abstract：:HIV infection is characterized by chronic immune activation and the establishment of a pool of latently infected cells. Antiretroviral therapy (ART) can suppress viral load to undetectable levels in peripheral blood by standard measure, however immune activation/chronic inflammation and latent infection persist and af...

journal_title：Vaccine

authors： Pallikkuth S,Bolivar H,Fletcher MA,Babic DZ,De Armas LR,Gupta S,Termini JM,Arheart KL,Stevenson M,Tung FY,Fischl MA,Pahwa S,Stone GW

更新日期：2020-06-02 00:00:00

abstract：:Delayed-type hypersensitivity (DTH) response to arthropod vector salivary proteins is associated with protection against pathogen transmission. Massive cDNA sequencing, high-throughput DNA plasmid construction and DNA immunisation were used to identify twelve DTH inducing proteins isolated from a Phlebotomus ariasi sa...

journal_title：Vaccine

authors： Oliveira F,Kamhawi S,Seitz AE,Pham VM,Guigal PM,Fischer L,Ward J,Valenzuela JG

更新日期：2006-01-16 00:00:00

abstract：:In this article, we review three mechanisms that contribute to sustaining serum antibody levels: (i) long-lived plasma cells; (ii) persisting or cross-reactive antigen, and (iii) polyclonal activation of all memory B cells. We also present a quantitative analysis of the secondary immune response that reveals the relat...

journal_title：Vaccine

authors： Traggiai E,Puzone R,Lanzavecchia A

更新日期：2003-06-01 00:00:00

abstract：:Influenza virus causes acute upper and lower respiratory infections and is the most likely, among known pathogens, to cause a large epidemic in humans. Influenza virus mutates rapidly, enabling it to evade natural and vaccine-induced immunity. Furthermore, influenza viruses can cross from animals to humans, generating...

journal_title：Vaccine

authors： Berlanda Scorza F,Tsvetnitsky V,Donnelly JJ

更新日期：2016-06-03 00:00:00

abstract：:Human papilloma virus (HPV) found in 99.7% of cervical cancers represents an attractive immunotherapeutic target for novel adjuvant dendritic cell (DC) immunotherapy. DC primed with HPV antigens have been shown to be capable of inducing CTL responses powerful enough to eradicate established murine tumours expressing H...

journal_title：Vaccine

authors： Adams M,Navabi H,Jasani B,Man S,Fiander A,Evans AS,Donninger C,Mason M

更新日期：2003-01-30 00:00:00

abstract：INTRODUCTION:Streptococcus pneumoniae is a capsulated bacterium that can cause severe infection in patients with thalassemia major, particularly those who have undergone splenectomy. The absence of the spleen as well as zinc deficiency in splenectomized patients with thalassemia major increases the possibility of devel...

journal_title：Vaccine

authors： Sari TT,Akib AAP,Gatot D,Roswita Harahap A,Bardosono S,Hadinegoro SRS

更新日期：2017-08-16 00:00:00

abstract：:OprI is an outer membrane lipoprotein from Pseudomonas aeruginosa, and when fused to a recombinant antigen, will exert adjuvant properties by engaging Toll-like receptor 2, leading to dendritic cell activation. Previous studies have shown that the Neospora caninum (Nc) antigens NcPDI, NcROP2 and NcROP40 are implicated...

journal_title：Vaccine

authors： Aguado-Martínez A,Basto AP,Tanaka S,Ryser LT,Nunes TP,Ortega-Mora LM,Arranz-Solís D,Leitão A,Hemphill A

更新日期：2019-01-14 00:00:00

abstract：:Presence of maternally-derived antibodies at time of immunization is known to often interfere with active infant immunization, although with variable degrees of clinical significance. In order to progressively decipher the rules that form the basis for these inhibitory effects on infant vaccine responses, two antigens...

journal_title：Vaccine

authors： Siegrist CA,Córdova M,Brandt C,Barrios C,Berney M,Tougne C,Kovarik J,Lambert PH

更新日期：1998-08-01 00:00:00

abstract：:Porcine circovirus type-2b (PCV2b) is the primary global causative agent of porcine circovirus-associated disease (PCVAD). In this study, we first constructed a novel chimeric virus (PCV1-2b) with the PCV2b capsid gene cloned into the backbone of non-pathogenic PCV1. A pathogenicity study conducted in caesarean-derive...

journal_title：Vaccine

authors： Beach NM,Ramamoorthy S,Opriessnig T,Wu SQ,Meng XJ

更新日期：2010-12-16 00:00:00

abstract：BACKGROUND:Vaccinations are an effective choice to stop disease outbreaks, including COVID-19. There is little research on individuals' COVID-19 vaccination decision-making. OBJECTIVE:We aimed to determine individual preferences for COVID-19 vaccinations in China, and to assess the factors influencing vaccination deci...

journal_title：Vaccine

authors： Leng A,Maitland E,Wang S,Nicholas S,Liu R,Wang J

更新日期：2021-01-08 00:00:00

abstract：:Capsular polysaccharides of Streptococcus pneumoniae are used to formulate polyvalent pneumococcal vaccines. A sensitive method, using high-performance anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD), has been developed to quantify the contamination of pneumococcal capsular polysaccharides...

journal_title：Vaccine

authors： Talaga P,Bellamy L,Moreau M

更新日期：2001-04-06 00:00:00

abstract：:The immunological enhancement characteristics of the immunopotentiator CVC1302 were evaluated for foot-and-mouth disease virus (FMDV) inactivated vaccine in pigs. Eight-week-old piglets were vaccinated with the foot-and-mouth disease (FMD) vaccine alone (FMD-vaccine group) or with the addition of CVC1302 (FMD-CVC1302 ...

journal_title：Vaccine

authors： Chen J,Yu X,Zheng Q,Hou L,Du L,Zhang Y,Qiao X,Hou J,Huang K

更新日期：2018-12-18 00:00:00

abstract：:Japanese rabies vaccine, a purified chick embryo cell vaccine manufactured by Kaketsuken (PCEC-K), is normally given subcutaneously; however, this requires a large amount of vaccine, and the pre-exposure vaccination regimen requires 6 months to complete. These factors often hamper appropriate vaccination. Therefore, w...

journal_title：Vaccine

authors： Shiota S,Khawplod P,Ahmed K,Mifune K,Nishizono A

更新日期：2008-11-25 00:00:00

abstract：:To evaluate the usefulness of a DNA vaccine for chickens, we constructed a plasmid vector expressing the Newcastle disease virus F protein (NDV-F) under the control of the human cytomegalovirus immediate early enhancer and chicken beta-actin gene promoter. One-week-old chickens injected intramusculary with the circula...

journal_title：Vaccine

authors： Sakaguchi M,Nakamura H,Sonoda K,Hamada F,Hirai K

更新日期：1996-06-01 00:00:00

abstract：:Meningococci bind human fH to down-regulate complement, which enhances survival of the bacteria in serum. A major fH ligand is the vaccine candidate, factor H-binding protein (fHbp). Although fHbp has been considered an essential meningococcal virulence factor, rarely, invasive isolates with absent fHbp genes or frame...

journal_title：Vaccine

authors： Giuntini S,Vu DM,Granoff DM

更新日期：2013-08-28 00:00:00