Determinants of infant responses to vaccines in presence of maternal antibodies.

abstract：BACKGROUND:Human papillomavirus (HPV) vaccination offers potential for primary prevention of HPV-related pre-cancers and cancers as demonstrated in clinical trials. Mathematical models have estimated the potential real-life impact of vaccination on the burden of cervical cancer (CC). However, these are restricted to ev...

journal_title：Vaccine

authors： Van Kriekinge G,Castellsagué X,Cibula D,Demarteau N

更新日期：2014-02-03 00:00:00

abstract：:This report provides an overview of methods used to conduct systematic reviews for the US Food and Drug Administration (FDA) Mini-Sentinel project, which is designed to inform the development of safety monitoring tools for FDA-regulated products including vaccines. The objective of these reviews was to summarize the l...

journal_title：Vaccine

authors： McPheeters ML,Sathe NA,Jerome RN,Carnahan RM

更新日期：2013-12-30 00:00:00

abstract：:A phase II safety and immunogenicity study of an oral-formalin inactivated enterotoxigenic Escherichia coli (ETEC) vaccine containing six colonization factors (CFA/I, CS1, CS2, CS3, CS4, CS5) and 1mg of recombinant cholera toxin B subunit (the CF-BS-ETEC vaccine) was carried out in an urban slum of Dhaka city in Bangl...

journal_title：Vaccine

authors： Qadri F,Ahmed T,Ahmed F,Bradley Sack R,Sack DA,Svennerholm AM

更新日期：2003-06-02 00:00:00

abstract：:The outbreak of highly pathogenic avian influenza virus in North American poultry during 2014 and 2015 demonstrated the devastating effects of the disease and highlighted the need for effective emergency vaccine prevention and control strategies targeted at currently circulating strains. This study evaluated the effic...

journal_title：Vaccine

authors： Balzli CL,Bertran K,Lee DH,Killmaster L,Pritchard N,Linz P,Mebatsion T,Swayne DE

更新日期：2018-01-02 00:00:00

abstract：:The immunogenicity and safety of an HPV-16/18 AS04-adjuvanted vaccine were assessed in women aged 26-55 years and compared with women aged 15-25 years in a Phase III, non-randomised, open-label, age-stratified study. Overall the vaccine was well tolerated and 100% seropositivity was achieved 1 month after the third do...

journal_title：Vaccine

authors： Schwarz TF,Spaczynski M,Schneider A,Wysocki J,Galaj A,Perona P,Poncelet S,Zahaf T,Hardt K,Descamps D,Dubin G,HPV Study Group for Adult Women.

更新日期：2009-01-22 00:00:00

abstract：:Reconstituted influenza virus (A/PR/8 strain) envelopes (RIVE) and influenza virus (A/Sichuan/87 (H3N2) strain) surface antigens were entrapped in dehydration-rehydration vesicles (DRV liposomes) composed of egg phosphatidylcholine (PC) or distearoyl phosphatidylcholine (DSPC DRV) and equimolar (32 mumol) cholesterol....

journal_title：Vaccine

authors： Gregoriadis G,Tan L,Ben-Ahmeida ET,Jennings R

更新日期：1992-01-01 00:00:00

abstract：:The highly pathogenic avian H5N1 influenza virus has the potential to incite a global pandemic. Therefore, there is an urgent need to develop effective vaccines against these viruses. Because it is difficult to predict which strain of influenza will cause a pandemic, it is advantageous to develop vaccines that will co...

journal_title：Vaccine

authors： Ichinohe T,Ainai A,Tashiro M,Sata T,Hasegawa H

更新日期：2009-10-23 00:00:00

abstract：:Human metapneumovirus (HMPV) is an important cause of acute respiratory tract disease for which the development of vaccine candidates is warranted. We have previously described the generation of an iscom matrix-adjuvanted HMPV fusion protein subunit vaccine (Fsol) and a live-attenuated vaccine (HMPVM11). Here, we eval...

journal_title：Vaccine

authors： Herfst S,Schrauwen EJ,de Graaf M,van Amerongen G,van den Hoogen BG,de Swart RL,Osterhaus AD,Fouchier RA

更新日期：2008-08-05 00:00:00

abstract：:A WHO workshop organized following the 2009 H1N1 pandemic recommended development of alternative influenza vaccine potency assays as high priority that could expedite the release of vaccine lots in the face of future influenza pandemics. We have developed an antibody independent, simple, high throughput receptor-bindi...

journal_title：Vaccine

authors： Khurana S,King LR,Manischewitz J,Coyle EM,Golding H

更新日期：2014-04-17 00:00:00

abstract：:After introduction of a mono-component vaccine, containing only pertussis toxoid (PT), the incidence of pertussis was significantly higher in the Gothenburg area among children during the period October 1, 1997 until end of 2006 compared to the Rest of Sweden where a vaccine containing PT and two other pertussis antig...

journal_title：Vaccine

authors： Advani A,Gustafsson L,Ahrén C,Mooi FR,Hallander HO

更新日期：2011-04-18 00:00:00

abstract：:A recombinant fowlpox vaccine with an H5 hemagglutinin gene insert protected chickens against clinical signs and death following challenge by nine different highly pathogenic H5 avian influenza viruses. The challenge viruses had 87.3 to 100% deduced hemagglutinin amino acid sequence similarity with the recombinant vac...

journal_title：Vaccine

authors： Swayne DE,Garcia M,Beck JR,Kinney N,Suarez DL

更新日期：2000-01-06 00:00:00

abstract：:Viral hepatitis remains a major contributor to the global disease burden. Mass immunisation strategies against hepatitis B have been adopted by more than 90 developing and industrialised countries. Countries with low hepatitis A endemicity are experiencing cyclical outbreaks and an epidemiological shift, with larger n...

journal_title：Vaccine

authors： Lopalco PL,Salleras L,Barbuti S,Germinario C,Bruguera M,Buti M,Domínguez A

更新日期：2000-10-15 00:00:00

abstract：OBJECTIVE:Using qualitative methods, we explored the implementation of California's 2007 influenza immunization requirements of hospital-based health care personnel (HCP). METHODS:We conducted nine case studies of California hospitals with different HCP vaccination rates and policies. Case studies consisted of intervi...

journal_title：Vaccine

authors： Khodyakov D,Uscher-Pines L,Lorick SA,Lindley MC,Shier V,Harris K

更新日期：2014-05-23 00:00:00

abstract：BACKGROUND:Each year, approximately 1,066 Cambodian children under five years old die of diarrhea, and 51% of these deaths are due to rotavirus gastroenteritis. Quantifying childhood hospitalizations caused by severe rotavirus infections is also important in demonstrating disease burden caused by this virus. The object...

journal_title：Vaccine

authors： Angkeabos N,Rin E,Vichit O,Chea C,Tech N,Payne DC,Fox K,Heffelfinger JD,Grabovac V,Nyambat B,Diorditsa S,Samnang C,Hossain MS

更新日期：2018-12-14 00:00:00

abstract：:Respiratory syncytial virus (RSV) causes severe respiratory illness in infants. There are no licensed vaccines to prevent RSV infection. The neonate receives short-term protection from maternally derived antibodies, which, however, can also interfere with the active response to vaccination. A RSV vaccine consisting of...

journal_title：Vaccine

authors： Garg R,Latimer L,Gerdts V,Potter A,van Drunen Littel-van den Hurk S

更新日期：2015-03-10 00:00:00

abstract：:WHO is now celebrating more than 30 years of freedom from smallpox. What was originally seen as a victory over an ancient scourge can now be viewed as an epidemiologically driven programme to overcome governmental inertia and under-achievement in delivering an off-patent vaccine. Though efforts are accelerating global...

journal_title：Vaccine

authors： Music S

更新日期：2010-01-22 00:00:00

abstract：:A gene associated with lipopolysaccharide (LPS) transport was cloned from a local clinical Vibrio cholerae O1 strain of the Ogawa serotype by using the Lactococcus lactis nisin-controlled expression (NICE) system. The V. cholerae wzm gene, which codes for an integral membrane transporter protein, was expressed and tar...

journal_title：Vaccine

authors： Zamri HF,Shamsudin MN,Rahim RA,Neela V

更新日期：2012-05-02 00:00:00

abstract：:Children in public care have poor health outcomes despite statutory health assessments. Incomplete immunisation of children entering the care system has been reported. Does this health disadvantage persist for those established in the care system? The immunisation status of 119 children in public care for at least 6 m...

journal_title：Vaccine

authors： Barnes P,Price L,Maddocks A,Cheung WY,Williams J,Jackson S,Mason B

更新日期：2005-04-15 00:00:00

abstract：:The proteolytic enzyme bromelain has been traditionally used to cleave the hemagglutinin (HA) protein at the C-terminus of the HA2 region to release the HA proteins from influenza virions. The bromelain cleaved HA (BHA) has been routinely used as an antigen to generate antiserum that is essential for influenza vaccine...

journal_title：Vaccine

authors： Wang W,Suguitan AL Jr,Zengel J,Chen Z,Jin H

更新日期：2012-01-20 00:00:00

abstract：:The bacillus Calmette Guérin (BCG) vaccine, the only licensed vaccine against TB, displays partial and variable efficacy, thus making the exploitation of novel vaccination strategies a major priority. Most of the current vaccines in pre-clinical or clinical development are based on the induction of T cells recognizing...

journal_title：Vaccine

authors： Larrouy-Maumus G,Layre E,Clark S,Prandi J,Rayner E,Lepore M,de Libero G,Williams A,Puzo G,Gilleron M

更新日期：2017-03-07 00:00:00

abstract：:In this study we have investigated the immunogenicity and antigenicity of synthetic immunocontraceptive vaccine candidates containing T- and B-cell epitopes arranged in different geometries. Two epitopes were selected, a B-cell epitope from fox sperm lactate dehydrogenase C(4) and a B-cell epitope from murine zona pel...

journal_title：Vaccine

authors： Sadler K,Bird PH,Brown LE,Jackson DC

更新日期：1999-10-14 00:00:00

abstract：:The persistence of anti-HBs protective levels in groups of children who had been immunized against Hepatitis B 5 and 10 years earlier, in their first year of life, has been studied. The results were analyzed according to the type of vaccine (both plasma-derived and DNA recombinant) and the number of doses administered...

journal_title：Vaccine

authors： Da Villa G,Peluso F,Picciotto L,Bencivenga M,Elia S,Pelliccia MG

更新日期：1996-11-01 00:00:00

abstract：:In order to provide an estimation of the direct and indirect benefits of pneumococcal vaccination with three protein-conjugate pneumococcal vaccines (PCV) we described the epidemiology and mortality from invasive pneumococcal disease (IPD) in Denmark between 2000 and 2005. Approximately 1080 cases were registered annu...

journal_title：Vaccine

authors： Harboe ZB,Valentiner-Branth P,Benfield TL,Christensen JJ,Hjuler T,Kaltoft M,Krogfelt KA,Lambertsen L,Konradsen HB

更新日期：2008-07-04 00:00:00

abstract：:Assuming that the level of Bacille Calmette Guerin (BCG) coverage gives a measure of access to immunisation services, it is possible to derive what fraction of infants are not immunised against measles due to under-utilisation of existing services (rather than unavailability of services). According to the most recent ...

journal_title：Vaccine

authors： Edmunds WJ,Gay NJ,Henao Restrepo AM,Olivé JM,Bele O

更新日期：2001-10-12 00:00:00

abstract：:Whole killed meningococci (Nm) and pertussis bacteria (Bp) were tested for mucosal immunogenicity and as mucosal adjuvants for an inactivated influenza virus vaccine given intranasally to unanaesthetized mice. Virus was given alone, or simply mixed with one of the bacterial preparations, in four doses at weekly interv...

journal_title：Vaccine

authors： Berstad AK,Andersen SR,Dalseg R,Dromtorp S,Holst J,Namork E,Wedege E,Haneberg B

更新日期：2000-03-17 00:00:00

abstract：:The present work was carried out to develop an effective vaccine to control infectious bursal disease (IBD). The very virulent infectious bursal disease virus (vvIBDV) was adapted to grow in Vero-cell line after three serial passages. The virus was then attenuated by further serial passages and pathogenicity of differ...

journal_title：Vaccine

authors： Rasool MH,Hussain I

更新日期：2006-04-05 00:00:00

abstract：:We compared pertussis surveillance systems of 16 European countries in the period 1998-2002. In twelve out of sixteen countries the system covered the general population. Ten countries relied on WHO case definition for surveillance of pertussis. Eleven countries applied laboratory tests, and eight of them used PCR for...

journal_title：Vaccine

authors： Tozzi AE,Pandolfi E,Celentano LP,Massari M,Salmaso S,Ciofi degli Atti ML,EUVAC-NET Study Group.

更新日期：2007-01-04 00:00:00

abstract：:To evaluate the usefulness of a DNA vaccine for chickens, we constructed a plasmid vector expressing the Newcastle disease virus F protein (NDV-F) under the control of the human cytomegalovirus immediate early enhancer and chicken beta-actin gene promoter. One-week-old chickens injected intramusculary with the circula...

journal_title：Vaccine

authors： Sakaguchi M,Nakamura H,Sonoda K,Hamada F,Hirai K

更新日期：1996-06-01 00:00:00

abstract：:Outer membrane proteins (OMP) are expressed in Gram-negative bacterial cell wall. OmpA from Klebsiella pneumoniae (KpOmpA) has been shown to bind and to activate selectively antigen presenting cells (APCs), eliciting protective CTL responses. In this study, we investigated whether OmpX, another member of the OMP famil...

journal_title：Vaccine

authors： Maisnier-Patin K,Malissard M,Jeannin P,Haeuw JF,Corbière JC,Hoeffel G,Gauchat JF,Nguyen T,Saez JM,Delneste Y

更新日期：2003-09-08 00:00:00

abstract：:Epidemic influenza occurs annually throughout the world and is accompanied by excess morbidity and mortality. Increasing the antigen content and topical administration of vaccine are two strategies being explored to improve the immune responses to trivalent inactivated influenza vaccine (TIV). We conducted a randomize...

journal_title：Vaccine

authors： Atmar RL,Keitel WA,Cate TR,Munoz FM,Ruben F,Couch RB

更新日期：2007-07-20 00:00:00