Abstract:
:Skin tests by prick technique offer considerable guidance in the diagnosis of food allergy. Negative prick skin tests are powerful evidence against food allergy. Positive food skin tests are slightly to moderately predictive of reaction to a food on DBPCFC. Oral food challenge is necessary for confirmation of food allergy, except where the history is overwhelmingly convincing. Open, incremental food challenge as described is diagnostic if negative, but only 50% of all positive open challenges are confirmed on blinded challenge. DBPCFC can be designed for any food with simple blinding techniques. The technique of DBPCFC can be modified for investigation of atypical symptoms.
journal_name
Clin Rev Allergy Immunoljournal_title
Clinical reviews in allergy & immunologyauthors
Williams LW,Bock SAdoi
10.1007/BF02737614subject
Has Abstractpub_date
1999-10-01 00:00:00pages
323-38issue
3eissn
1080-0549issn
1559-0267journal_volume
17pub_type
杂志文章,评审abstract::Resolvins, belonging to the group of specialized proresolving mediators (SPMs), are metabolic products of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) and are synthesized during the initial phases of acute inflammatory responses to promote the resolution of inflammation. Resolvins are produced for termination of ne...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-019-08754-9
更新日期:2020-02-01 00:00:00
abstract::Pemphigus is a group of rare, potentially devastating autoimmune diseases of the skin and mucous membranes with high morbidity and potentially lethal outcome. The major clinical variant, pemphigus vulgaris (PV) is caused by a loss of intercellular adhesion of epidermal keratinocytes which is induced by IgG autoantibod...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-017-8662-z
更新日期:2018-02-01 00:00:00
abstract::Sarcoidosis is a systemic granulomatous disease that frequently involves the lung. Although classically thought of as a restrictive lung disease, airway obstruction has become a recognized feature of the disease in the past years. Sarcoidosis can affect the airway at any level and when the involvement includes small a...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1385/CRIAI:25:2:115
更新日期:2003-10-01 00:00:00
abstract::This review includes a variety of extremely rare and unusual hymenoptera sting (HS) circumstances with regard to sting localization, geographic region, massivity of multiple stings, and particularly related to clinical symptoms. Such reactions occur in a temporal relationship to HS (s), differ from typical allergic sy...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-014-8434-y
更新日期:2014-08-01 00:00:00
abstract::Primary sclerosing cholangitis (PSC) is a rare chronic cholestatic disease of the liver and bile ducts that is associated with inflammatory bowel disease, generally leads to end-stage liver disease, and is complicated by malignancies of the biliary tree and the large intestine. The pathogenesis of PSC remains enigmati...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-008-8085-y
更新日期:2009-02-01 00:00:00
abstract::Pruritus, fatigue, and metabolic bone disease are frequent complications of cholestatic liver diseases, which can be quite distressing for the patient and can considerably reduce the quality of life. The molecular pathogenesis of these extrahepatic manifestations of cholestasis is poorly understood, and hypotheses to ...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1385/CRIAI:28:2:147
更新日期:2005-04-01 00:00:00
abstract::Inflammatory bowel disease (IBD) is a chronic immune-mediated inflammatory condition primarily involving the gastrointestinal tract. It includes Crohn's disease (CD), ulcerative colitis (UC), and a less common phenotype-indeterminate colitis. It is thought to result from a complex interplay of environmental, microbial...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-018-8690-3
更新日期:2019-10-01 00:00:00
abstract::As summarized in Table 1, the literature consistently supports the hypothesis that allergic asthmatic patients have seasonal BHR changes that parallel allergen exposure. These seasonal changes appear to be preventable by treatment with corticosteroids (systemic, inhaled, or nasal), disodium cromoglycate, and immunothe...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/BF02826585
更新日期:1997-07-01 00:00:00
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journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1385/CRIAI:30:1:013
更新日期:2006-02-01 00:00:00
abstract::Antityrosinase antibody is a newly detected antibody in the sera of patients with melanoma or vitiligo. The serum level of the antibody is measured by enzyme-linked immunosorbent assay (ELISA). The autoantigen is tyrosinase itself, the enzyme that participates in pigment (melanin) formation by both melanocytes and mel...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/BF02737633
更新日期:1998-10-01 00:00:00
abstract::Atherosclerosis is an inflammatory disease, and several antigens have been shown to activate the immune response and affect the development of atherogenesis. This suggests that modulation of the immune system could represent a useful approach to prevent and/or treat this disorder. A vaccination approach might be a use...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-009-8145-y
更新日期:2010-04-01 00:00:00
abstract::In the vast database of peer-reviewed articles, the number of 2018 papers published retrieved using the "autoimmunity" keyword remained unchanged compared with the brilliant results of 2017 while returning above a 5% share within the immunology field, after the brisk decrease of this ratio in 2017. As in the past 12 y...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章
doi:10.1007/s12016-019-08745-w
更新日期:2019-06-01 00:00:00
abstract::Strategies to improve patients' adherence to treatment are essential to reduce the great health and economic burden of allergic rhinitis and asthma. Mobile phone applications (apps) for a better management of allergic diseases are growing in number, but their usefulness for doctors and patients is still debated. Contr...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s12016-016-8542-y
更新日期:2019-04-01 00:00:00
abstract::Chronic hyperplastic eosinophilic sinusitis (CHES) is a T-helper (Th)2-like, lymphocyteinitiated, eosinophil-rich inflammatory disease. The complex immune interactions required to orchestrate these processes begin with the presentation of antigen by mature dendritic cells to Th lymphocytes that display the appropriate...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1385/CRIAI:30:3:195
更新日期:2006-06-01 00:00:00
abstract::Although the relative contributions of T cells and B cells in Sjögren's syndrome (SS) are far from being settled, recent studies have suggested a crucial role for B cells in its pathophysiology. Early investigations have focused on the ability of B cells to produce autoantibodies, and new studies have enlarged the ran...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-007-8000-y
更新日期:2007-06-01 00:00:00
abstract::Bronchial hyperresponsiveness (BHR) is a characteristic feature of asthma, and individuals with this disease respond to a range of physiological and chemical insults that are otherwise innocuous to healthy subjects, suggesting that the mechanisms underlying this phenomenon are characteristic of the asthma phenotype. B...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1385/CRIAI:31:2:143
更新日期:2006-10-01 00:00:00
abstract::The provider's ability to judge the severity of a patient's illness is a vital part of the care of chronic disorders. In the treatment of asthma, it should extend beyond the objectively quantifiable measures of obstruction or inflammation. "Interference with activities of daily living" is a highly subjective assessmen...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1385/CRIAI:29:2:159
更新日期:2005-10-01 00:00:00
abstract::Pulmonary function testing is useful for the diagnosis and management of a variety of pulmonary conditions, and the most commonly obtained component is spirometry. Spirometry is most useful in the evaluation of obstructive airway disorders but can be a helpful tool in the management of patients with chest restriction ...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-009-8128-z
更新日期:2009-12-01 00:00:00
abstract::Prognosis of several autoimmune diseases, especially rheumatoid arthritis (RA), ankylosing spondylitis, Crohn's disease (CD), and psoriasis, usually refractory to conventional treatment improved considerably with the introduction of tumor necrosis factor alpha (TNF-alpha) antagonistic agents, which is now available (i...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-009-8140-3
更新日期:2010-04-01 00:00:00
abstract::Celiac disease is a complex immune-mediated gluten-sensitive enteropathy with protean clinical manifestations. It is manifest in genetically predisposed individuals who ingest gluten in varying amounts. In broad terms, it is thought to affect 1% of the population in the USA. More specifically, the prevalence increases...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-018-8691-2
更新日期:2019-10-01 00:00:00
abstract::Allergic diseases are surprisingly common, chronic health conditions. The primary location where the vast majority of people are exposed to allergens and other substances is in their home. This means it is important to understand home environments and how a home's systems function and interact-and that how we occupy t...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-018-8724-x
更新日期:2019-12-01 00:00:00
abstract::Air pollution is defined as the presence of noxious substances in the air at levels that impose a health hazard. Thus, there has been long-standing interest in the possible role of indoor and outdoor air pollutants on the development of respiratory disease. In this regard, asthma has been of particular interest but ma...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-019-08730-3
更新日期:2019-12-01 00:00:00
abstract::Asthma is the most common potentially serious medical problem to complicate pregnancy. Recent reports suggest that 7 of every 100 pregnant women suffer from asthma during pregnancy. Asthmatic women have been shown to be at an increased risk of complications during pregnancy. This may be secondary to inadequately contr...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1385/CRIAI:26:3:139
更新日期:2004-06-01 00:00:00
abstract::The expert panel report version 2 (EPR-2) is a comprehensive set of recommendations for the evaluation and treatment of asthma. However, physicians demonstrate scant adoption of many of the key evaluation and treatment components of the EPR-2, with primary care physicians being less likely to adopt EPR-2 recommendatio...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1385/CRIAI:27:2:065
更新日期:2004-10-01 00:00:00
abstract::Primary biliary cirrhosis (PBC) is characterized histologically by the presence of chronic non-suppurative destructive cholangitis of the small interlobular bile duct, leading to chronic progressive cholestasis. Most PBC patients are asymptomatic and have a reasonable prognosis, but a few develop esophageal varices or...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-015-8482-y
更新日期:2015-06-01 00:00:00
abstract::Autoimmune diseases are immune disorders characterized by T cell hyperactivity and B cell overstimulation leading to overproduction of autoantibodies. Although the pathogenesis of various autoimmune diseases remains to be elucidated, environmental factors have been thought to contribute to the initiation and maintenan...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-013-8402-y
更新日期:2014-10-01 00:00:00
abstract::Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of intracellular granule components that function by capturing and destroying microbes, including viral, fungal, bacterial, and protozoal pat...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-020-08804-7
更新日期:2020-08-01 00:00:00
abstract::Bronchial hyperresponsiveness (BHR) is an essential part of the definition of asthma. Although our understanding of the allergic inflammatory and immunologic mechanisms of asthma have markedly increased, the mechanism of BHR remains to be elucidated. Increased BHR is associated temporally with exposure to allergens, c...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1385/CRIAI:24:1:85
更新日期:2003-02-01 00:00:00
abstract::To investigate the prevalence of anti-third generation cyclic citrullinated peptide antibodies (anti-CCP3) in patients with systemic connective tissue diseases, we assembled a training set consisting of 115 patients with rheumatoid arthritis (RA), 52 with Calcinosis, Raynaud's phenomenon, oesophageal dysmotility, scle...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章
doi:10.1007/BF02686081
更新日期:2007-02-01 00:00:00
abstract::Sarcoidosis has innumerable clinical manifestations, as the disease may affect every body organ. Furthermore, the severity of sarcoidosis involvement may range from an asymptomatic state to a life-threatening condition. This manuscript reviews a wide variety of common and less common clinical characteristics of sarcoi...
journal_title:Clinical reviews in allergy & immunology
pub_type: 杂志文章,评审
doi:10.1007/s12016-014-8450-y
更新日期:2015-08-01 00:00:00