Autoimmunity in 2018.

abstract：:Tumor necrosis factor-α (TNF-α) is a central regulator of inflammation, and TNF-α antagonists may be effective in treating inflammatory disorders in which TNF-α plays a major pathogenic role. TNF-α has also been associated with inflammatory mechanisms related to implantation, placentation, and pregnancy outcome. TNF-α...

journal_title：Clinical reviews in allergy & immunology

authors： Alijotas-Reig J,Esteve-Valverde E,Ferrer-Oliveras R,Llurba E,Gris JM

更新日期：2017-08-01 00:00:00

abstract：:Wegener's granulomatosis (WG) is a chronic, relapsing, systemic necrotizing vasculitis with typical pathologic findings of granulomatous inflammation and pauci-immune vasculitis. Untreated, the condition has a very high mortality, and contemporary treatment strategies carry a high risk of treatment-related morbidity. ...

journal_title：Clinical reviews in allergy & immunology

authors： Hinze CH,Colbert RA

更新日期：2008-06-01 00:00:00

abstract：:As physiological pathways of intercellular communication produced by all cells, cytokines are involved in the pathogenesis of inflammatory insulitis as well as pivotal mediators of immune homeostasis. Proinflammatory cytokines including interleukins, interferons, transforming growth factor-β, tumor necrosis factor-α, ...

journal_title：Clinical reviews in allergy & immunology

authors： Kaminitz A,Ash S,Askenasy N

更新日期：2017-06-01 00:00:00

abstract：:Atherosclerosis is a disease of the vascular wall, which predominantly affects large and medium-sized arteries. It represents a leading cause of morbidity and mortality in the Western world. In the last few decades, it has been clearly shown that immune system plays a relevant role in atherogenesis. The effectors of b...

journal_title：Clinical reviews in allergy & immunology

authors： Bassi N,Zampieri S,Ghirardello A,Tonon M,Zen M,Cozzi F,Doria A

更新日期：2009-08-01 00:00:00

abstract：:Cashew plant (Anacardium occidentale L.) is the most relevant species of the Anacardium genus. It presents high economic value since it is widely used in human nutrition and in several industrial applications. Cashew nut is a well-appreciated food (belongs to the tree nut group), being widely consumed as snacks and in...

journal_title：Clinical reviews in allergy & immunology

authors： Mendes C,Costa J,Vicente AA,Oliveira MBPP,Mafra I

更新日期：2019-08-01 00:00:00

abstract：:Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of intracellular granule components that function by capturing and destroying microbes, including viral, fungal, bacterial, and protozoal pat...

journal_title：Clinical reviews in allergy & immunology

authors： Mutua V,Gershwin LJ

更新日期：2020-08-01 00:00:00

abstract：:Autoimmune diseases are immune disorders characterized by T cell hyperactivity and B cell overstimulation leading to overproduction of autoantibodies. Although the pathogenesis of various autoimmune diseases remains to be elucidated, environmental factors have been thought to contribute to the initiation and maintenan...

journal_title：Clinical reviews in allergy & immunology

authors： Liu Y,Yin H,Zhao M,Lu Q

更新日期：2014-10-01 00:00:00

abstract：:Airway remodeling is an established feature of asthma. Histologic examination is essential in the assessment of remodeling that is a pathologic concept. Examinations of autopsied or resected lung have enabled detailed morphologic and morphometric studies and have provided fundamental knowledge of airway remodeling in ...

journal_title：Clinical reviews in allergy & immunology

authors： Niimi A,Matsumoto H,Takemura M,Ueda T,Nakano Y,Mishima M

更新日期：2004-08-01 00:00:00

abstract：:Glatiramer acetate (GA) significantly ameliorates multiple sclerosis and was initially discovered through its effects on the animal model experimental autoimmune encephalomyelitis (EAE). Guillain-Barré syndrome (GBS) is a relatively common demyelinating disease of peripheral nerves for which there is a parallel animal...

journal_title：Clinical reviews in allergy & immunology

authors： Aronovich R,Katzav A,Chapman J

更新日期：2012-04-01 00:00:00

abstract：:This review includes a variety of extremely rare and unusual hymenoptera sting (HS) circumstances with regard to sting localization, geographic region, massivity of multiple stings, and particularly related to clinical symptoms. Such reactions occur in a temporal relationship to HS (s), differ from typical allergic sy...

journal_title：Clinical reviews in allergy & immunology

authors： Mingomataj EÇ,Bakiri AH,Ibranji A,Sturm GJ

更新日期：2014-08-01 00:00:00

abstract：:Calcium is the most abundant mineral in the human body and is central to many physiological processes, including immune system activation and maintenance. Studies continue to reveal the intricacies of calcium signalling within the immune system. Perhaps the most well-understood mechanism of calcium influx into cells i...

journal_title：Clinical reviews in allergy & immunology

authors： Froghi S,Grant CR,Tandon R,Quaglia A,Davidson B,Fuller B

更新日期：2021-01-06 00:00:00

abstract：:Asthma is the most common potentially serious medical problem to complicate pregnancy. Recent reports suggest that 7 of every 100 pregnant women suffer from asthma during pregnancy. Asthmatic women have been shown to be at an increased risk of complications during pregnancy. This may be secondary to inadequately contr...

journal_title：Clinical reviews in allergy & immunology

authors： Namazy JA,Schatz M

更新日期：2004-06-01 00:00:00

abstract：:G protein-coupled receptors (GPCRs) constitute the largest family of plasma membrane receptors in nature and mediate the effects of a variety of extracellular signals, such as hormone, neurotransmitter, odor, and light signals. Due to their involvement in a broad range of physiological and pathological processes and t...

journal_title：Clinical reviews in allergy & immunology

authors： Zhao M,Wang Z,Yang M,Ding Y,Zhao M,Wu H,Zhang Y,Lu Q

更新日期：2021-01-07 00:00:00

abstract：:The diagnosis of celiac disease (CD) remains a clinical challenge based on the incomplete specificity and sensitivity rates of current non-invasive tests. Furthermore, histological assessments fail to identify all overt cases and, in particular, do not manifest pathognomonic alterations in silent cases. Accordingly, t...

journal_title：Clinical reviews in allergy & immunology

authors： Matthias T,Pfeiffer S,Selmi C,Eric Gershwin M

更新日期：2010-04-01 00:00:00

abstract：:Hereditary angioedema (HAE) patients experience recurrent local swelling in various parts of the body including painful swelling of the intestine and life-threatening laryngeal oedema. Most HAE literature is about attacks located in one anatomical site, though it is mentioned that HAE attacks may also involve multiple...

journal_title：Clinical reviews in allergy & immunology

authors： Hofman ZL,Relan A,Hack CE

更新日期：2016-02-01 00:00:00

abstract：:Through the last decade, clinical immunology has witnessed a considerable progress in understanding the role of the innate immunity in human host defense, with Toll-like receptors (TLRs) being the most extensively innate immune receptors investigated. Growing literature documents the relevance of TLR signaling pathway...

journal_title：Clinical reviews in allergy & immunology

authors： Suhir H,Etzioni A

更新日期：2010-02-01 00:00:00

abstract：:Patients with immunodeficiencies or some types of autoimmune diseases are dependent on safe therapy with intravenous immunoglobulins. State-of-the-art manufacturing processes provide a high safety standard by incorporating virus elimination procedures into the manufacturing process. Based on their mechanism, these pro...

journal_title：Clinical reviews in allergy & immunology

authors： Boschetti N,Stucki M,Späth PJ,Kempf C

更新日期：2005-12-01 00:00:00

abstract：:Air pollution is defined as the presence of noxious substances in the air at levels that impose a health hazard. Thus, there has been long-standing interest in the possible role of indoor and outdoor air pollutants on the development of respiratory disease. In this regard, asthma has been of particular interest but ma...

journal_title：Clinical reviews in allergy & immunology

authors： Hassoun Y,James C,Bernstein DI

更新日期：2019-12-01 00:00:00

abstract：:Systemic vasculitides are a group of rare diseases characterized by inflammation of the arterial or venous vessel wall, causing stenosis or thrombosis. Clinical symptoms may be limited to skin or to other organs or may include multiple manifestations as systemic conditions. The pathogenesis is related to the presence ...

journal_title：Clinical reviews in allergy & immunology

authors： Chimenti MS,Ballanti E,Triggianese P,Perricone R

更新日期：2015-12-01 00:00:00

abstract：:Atherosclerosis is an inflammatory disease, and several antigens have been shown to activate the immune response and affect the development of atherogenesis. This suggests that modulation of the immune system could represent a useful approach to prevent and/or treat this disorder. A vaccination approach might be a use...

journal_title：Clinical reviews in allergy & immunology

authors： de Carvalho JF,Pereira RM,Shoenfeld Y

更新日期：2010-04-01 00:00:00

abstract：:Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene that results in abnormal viscous mucoid secretions in multiple organs and whose main clinical features are pancreatic insufficiency and chronic endobronchial infection. Although it was i...

journal_title：Clinical reviews in allergy & immunology

authors： Voter KZ,Ren CL

更新日期：2008-12-01 00:00:00

abstract：:During the last decade, B regulatory cells are appreciated to have a central role in preventing autoimmunity and maintaining self-tolerance. They are characterized by expressing different phenotypic markers and the production of either IL-10 or TGF-β or both. The recent recognition of Fas ligand expressing B regulator...

journal_title：Clinical reviews in allergy & immunology

authors： Vadasz Z,Toubi E

更新日期：2017-06-01 00:00:00

abstract：:Illicit stimulants, such as cocaine, amphetamine, and their derivatives (e.g., "ecstasy"), continue to exact heavy toll on health care in both developed and developing countries. The US Department of Health and Human Service reported over one million illicit drug-related emergency department visits in 2010, which was ...

journal_title：Clinical reviews in allergy & immunology

authors： Tseng W,Sutter ME,Albertson TE

更新日期：2014-02-01 00:00:00

abstract：:Acid anhydrides are used by chemical industries as plasticizers. Trimellitic acid (TMA) is an acid anhydride widely utilized in factories to produce paints, varnishes, and plastics. In addition to causing direct irritant effects, TMA can augment antibody responses in exposed factory workers leading to occupational ast...

journal_title：Clinical reviews in allergy & immunology

authors： Ghosh D,Bernstein JA

更新日期：2020-08-01 00:00:00

abstract：:Rheumatoid arthritis and spondyloarthritis are inflammatory joint disorders with an autoimmune pathogenesis and systemic involvement. The skin is one of the most frequently affected extraarticular sites with a number of manifestations or distinct diseases, including common conditions, such as rheumatoid nodules and ps...

journal_title：Clinical reviews in allergy & immunology

authors： Cugno M,Gualtierotti R,Meroni PL,Marzano AV

更新日期：2018-04-01 00:00:00

abstract：:Patients presenting to the emergency department (ED) or clinic with acute exacerbation of asthma (AEA) can be very challenging varying in both severity and response to therapy. High-dose, frequent or continuous nebulized short-acting beta2 agonist (SABA) therapy that can be combined with a short-acting muscarinic anta...

journal_title：Clinical reviews in allergy & immunology

authors： Albertson TE,Sutter ME,Chan AL

更新日期：2015-02-01 00:00:00

abstract：:Antityrosinase antibody is a newly detected antibody in the sera of patients with melanoma or vitiligo. The serum level of the antibody is measured by enzyme-linked immunosorbent assay (ELISA). The autoantigen is tyrosinase itself, the enzyme that participates in pigment (melanin) formation by both melanocytes and mel...

journal_title：Clinical reviews in allergy & immunology

authors： Merimsky O,Shoenfeld Y,Fishman P

更新日期：1998-10-01 00:00:00

abstract：:Pulmonary function testing is useful for the diagnosis and management of a variety of pulmonary conditions, and the most commonly obtained component is spirometry. Spirometry is most useful in the evaluation of obstructive airway disorders but can be a helpful tool in the management of patients with chest restriction ...

journal_title：Clinical reviews in allergy & immunology

authors： Liou TG,Kanner RE

更新日期：2009-12-01 00:00:00

abstract：:A bulk of literature demonstrated that respiratory allergy, and especially asthma, is prevalent in males during childhood, while it becomes more frequent in females from adolescence, i.e., after menarche, to adulthood. The mechanisms underlying the difference between females and males are the effects on the immune res...

journal_title：Clinical reviews in allergy & immunology

authors： Ridolo E,Incorvaia C,Martignago I,Caminati M,Canonica GW,Senna G

更新日期：2019-06-01 00:00:00

abstract：:Although allergic asthma was described to be associated with the presence of mucosal T helper (Th)2 cells, it is not entirely clear which factors are responsible for priming of T cells to differentiate into Th2 effector cells in this disease. Interleukin (IL)-6 has been recognized as important because it is secreted b...

journal_title：Clinical reviews in allergy & immunology

authors： Doganci A,Sauer K,Karwot R,Finotto S

更新日期：2005-06-01 00:00:00