Hydrogenation of polyunsaturated fatty acids by human colonic bacteria.

Abstract:

:Emulsions of the fatty acids linoleic (C18:2 n-6), alpha-linolenic (C18:3 n-3) and arachidonic acid (C20:4 n-6) were incubated for 4 h under anaerobic conditions with human faecal suspensions. Linoleic acid was significantly decreased (P < 0.001) and there was a significant rise (P < 0.05) in its hydrogenation product, stearic acid. Linolenic acid was also significantly decreased (P < 0.01), and significant increases in C18:3 cis-trans isomers (P < 0.01) and linoleic acid (P < 0.05) were seen. With each acid, there were non-significant increases in acids considered to be intermediates in biohydrogenation. The study provides evidence that bacteria from the human colon can hydrogenate C18 essential polyunsaturated fatty acids. However, with arachidonic acid there was no evidence of hydrogenation.

journal_name

Lett Appl Microbiol

authors

Howard FA,Henderson C

doi

10.1046/j.1365-2672.1999.00616.x

subject

Has Abstract

pub_date

1999-09-01 00:00:00

pages

193-6

issue

3

eissn

0266-8254

issn

1472-765X

journal_volume

29

pub_type

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