Computerized and traditional stroop task dysfunction in HIV-1 infection.

Abstract:

:Controlled processing, response inhibition, and set adoption were examined in 51 HIV-1 infected participants and 21 uninfected controls who were administered a vocal reaction time (RT) version of the Stroop task (Stroop-RT; J. R. Stroop, 1935) as well as the traditional 100 item paper-and-pencil version. Response set expectancies on the Stroop-RT were manipulated by presenting 50% of trials in homogenous blocks and randomly varying the stimulus type during the remaining trials. As hypothesized, HIV seropositive (HIV+) participants were significantly slower than HIV seronegative controls on both versions of the Stroop. Significant interference effects were apparent on the paper-and-pencil version of the Stroop, but were not as prominent on the Stroop-RT. The HIV+ participants did profit from the blocking manipulation on the Stroop-RT, suggesting that set adoption is retained in HIV infection. These data suggest that HIV infection may result in deficient response inhibition, possibly secondary to frontostriatal dysfunction and dopaminergic alterations.

journal_name

Neuropsychology

journal_title

Neuropsychology

authors

Hinkin CH,Castellon SA,Hardy DJ,Granholm E,Siegle G

doi

10.1037//0894-4105.13.2.306

subject

Has Abstract

pub_date

1999-04-01 00:00:00

pages

306-16

issue

2

eissn

0894-4105

issn

1931-1559

journal_volume

13

pub_type

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