The relation of anxiety and cognition in Parkinson's disease.

Abstract:

OBJECTIVE:Parkinson's disease (PD) has long been conceptualized as a motor disorder, but nonmotor symptoms also manifest in the disease and significantly reduce quality of life. Anxiety and cognitive dysfunction are prevalent nonmotor symptoms, even in early disease stages, but the relation between these symptoms remains poorly understood. We examined self-reported anxiety and neurocognitive function, indexed by measures of executive function (set-shifting and phonemic fluency), categorical fluency, and attention/working memory. We hypothesized that anxiety would correlate with cognitive performance. METHOD:The Beck Anxiety Inventory and cognitive tests (Trail Making, Verbal Fluency, Digit Span) were administered to 77 nondemented adults with mild to moderate idiopathic PD (39 men, 38 women; Mage = 62.9 years). RESULTS:Higher anxiety was associated with more advanced disease stage and severity and with poorer set-shifting when using a derived metric to account for motoric slowing. Depression correlated with greater anxiety and disease severity, but not with cognitive performance. CONCLUSIONS:Our findings support the association of anxiety with a specific domain of executive function, set-shifting, in nondemented individuals with mild to moderate PD, raising the possibility that treatment of anxiety may alleviate aspects of executive dysfunction in this population. (PsycINFO Database Record

journal_name

Neuropsychology

journal_title

Neuropsychology

authors

Reynolds GO,Hanna KK,Neargarder S,Cronin-Golomb A

doi

10.1037/neu0000353

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

596-604

issue

6

eissn

0894-4105

issn

1931-1559

pii

2017-17707-001

journal_volume

31

pub_type

杂志文章
  • Diverse attention deficits in patients with neurologically symptomatic and asymptomatic Wilson's disease.

    abstract:OBJECTIVE:Cognitive deficits in patients with Wilson's disease (WD) have been reported in several studies, but there was no detailed analysis of the various components of attention, one of the most significant factors of the executive system. Our study determined the pattern of deficits in attention subsystems in WD pa...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000103

    authors: Iwański S,Seniów J,Leśniak M,Litwin T,Członkowska A

    更新日期:2015-01-01 00:00:00

  • Structural brain markers are differentially associated with neurocognitive profiles in socially marginalized people with multimorbid illness.

    abstract:OBJECTIVE:The authors examined associations between complementary fronto-temporal structural brain measures (gyrification, cortical thickness) and neurocognitive profiles in a multimorbid, socially marginalized sample. METHOD:Participants were recruited from single-room occupancy hotels and a downtown community courth...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000304

    authors: Gicas KM,Giesbrecht CJ,Panenka WJ,Lang DJ,Smith GN,Vila-Rodriguez F,Leonova O,Jones AA,Barr AM,Procyshyn RM,Buchanan T,MacEwan GW,Su W,Vertinsky AT,Rauscher A,Honer WG,Thornton AE

    更新日期:2017-01-01 00:00:00

  • Individual differences in reasoning and visuospatial attention are associated with prefrontal and parietal white matter tracts in healthy older adults.

    abstract:OBJECTIVE:Although reasoning and attention are 2 cognitive processes necessary for ensuring the efficiency of many everyday activities in older adults, the role of white matter integrity in these processes has been little studied. This is an important question due to the role of white matter integrity as a neural subst...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000264

    authors: Monge ZA,Greenwood PM,Parasuraman R,Strenziok M

    更新日期:2016-07-01 00:00:00

  • Attentional networks reveal executive function deficits in posttraumatic stress disorder.

    abstract::Executive function was assessed with the Trail Making Test (Army Individual Test Battery; M. D. Lezak, 1983), the Comprehensive Trail Making Test (C. Reynolds, 2002), and a neurocognitive measure of executive control (Attentional Network Task [ANT]; J. I. Fan, B. D. McCandliss, T. Somer, A. Raz, & M. I. Posner, 2002) ...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.21.3.275

    authors: Leskin LP,White PM

    更新日期:2007-05-01 00:00:00

  • Age-associated losses of brain volume predict longitudinal cognitive declines over 8 to 20 years.

    abstract::Absolute differences in global brain volume predict differences in cognitive ability among healthy older adults. However, absolute differences confound lifelong differences in brain size with amounts of age-related shrinkage. Measurements of cerebrospinal fluid (CSF) volume were made to estimate age-related shrinkage ...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.22.1.3

    authors: Rabbitt P,Ibrahim S,Lunn M,Scott M,Thacker N,Hutchinson C,Horan M,Pendleton N,Jackson A

    更新日期:2008-01-01 00:00:00

  • HIV-associated prospective memory impairment increases risk of dependence in everyday functioning.

    abstract::HIV infection is associated with impairments in prospective memory (ProM), an aspect of episodic memory that refers to the ability to execute a future intention, such as remembering to take a medication at a specific time. The current study sought to examine the relationship between HIV-associated ProM impairment and ...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.22.1.110

    authors: Woods SP,Iudicello JE,Moran LM,Carey CL,Dawson MS,Grant I,HIV Neurobehavioral Research Center Group.

    更新日期:2008-01-01 00:00:00

  • Recollection- and familiarity-based memory in healthy aging and amnestic mild cognitive impairment.

    abstract::Little is known about the cognitive mechanisms of the memory impairment associated with amnestic mild cognitive impairment (aMCI). We explored recollection and familiarity in 27 healthy young adults, 45 healthy older adults, and 17 individuals with aMCI. Relative to the younger adults, recollection was reduced in the ...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.22.2.177

    authors: Anderson ND,Ebert PL,Jennings JM,Grady CL,Cabeza R,Graham SJ

    更新日期:2008-03-01 00:00:00

  • Space-based inhibition of return in children with spina bifida.

    abstract::Inhibition of return (IOR) refers to an increase in time to react to a target in a previously attended location. Children with spina bifida meningomyelocele (SBM) and hydrocephalus have congenital dysmorphology of the midbrain, a brain region associated with the control of covert orienting in general and with IOR in p...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.19.4.456

    authors: Dennis M,Edelstein K,Copeland K,Frederick JA,Francis DJ,Hetherington R,Blaser SE,Kramer LA,Drake JM,Brandt ME,Fletcher JM

    更新日期:2005-07-01 00:00:00

  • Gender-related dissociations of categorical fluency in normal subjects and in subjects with Alzheimer's disease.

    abstract::Semantic fluency tasks, with the categories of birds and furniture as stimuli, were administered to normal subjects and patients with Alzheimer's disease (AD). Normal subjects showed a gender-related double dissociation consistent with the literature data because men were more fluent with the birds category and women ...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.21.2.207

    authors: Marra C,Ferraccioli M,Gainotti G

    更新日期:2007-03-01 00:00:00

  • Cerebral lateralization and cognitive functioning in patients with congenital adrenal hyperplasia.

    abstract::A battery of tests was administered to 17 patients with congenital adrenal hyperplasia (CAH) and 17 normal controls to investigate the effect of prenatal androgen exposure on cerebral lateralization and cognitive performance. Individuals were compared on measures of hand preference, verbal and performance IQ, and temp...

    journal_title:Neuropsychology

    pub_type: 临床试验,杂志文章

    doi:10.1037//0894-4105.14.3.370

    authors: Kelso WM,Nicholls ME,Warne GL,Zacharin M

    更新日期:2000-07-01 00:00:00

  • Depressive symptoms precede cognitive impairment in de novo Parkinson's disease patients: Analysis of the PPMI cohort.

    abstract:INTRODUCTION:Nonmotor symptoms, including depression, anxiety, apathy, and cognitive dysfunction, are common in Parkinson's disease (PD). Although a link between mood symptoms and cognitive impairment in PD has been theorized vis-à-vis striatal dopamine depletion, studies have been inconsistent regarding the relationsh...

    journal_title:Neuropsychology

    pub_type: 杂志文章,多中心研究

    doi:10.1037/neu0000583

    authors: Jones JD,Kurniadi NE,Kuhn TP,Szymkowicz SM,Bunch J,Rahmani E

    更新日期:2019-11-01 00:00:00

  • Influence of blast exposure on cognitive functioning in combat veterans.

    abstract:OBJECTIVE:We evaluated the contribution of blast-pressure severity to cognitive functioning beyond posttraumatic stress disorder (PTSD) severity and traumatic brain injury (TBI). METHOD:Post-9/11 veterans (N = 254, 86.22% male) completed the Wechsler Adult Intelligence Scale (WAIS-IV) and Trail Making Test (TMT). The ...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000672

    authors: Martindale SL,Ord AS,Rowland JA

    更新日期:2020-07-16 00:00:00

  • Cognition and daily life functioning among persons with serious mental illness: A cluster analytic examination of heterogeneity on the Test of Grocery Shopping Skills.

    abstract:OBJECTIVE:To characterize variability in daily life functioning among individuals with serious mental illness based on a naturalistic performance measure of grocery shopping and standard neuropsychological tasks using cluster analytic methods. METHODS:A naturalistic performance measure, the Test of Grocery Shopping Sk...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000700

    authors: Harris M,Blanco EA,Rempfer M

    更新日期:2021-01-01 00:00:00

  • Repetition priming and recognition memory in younger and older persons: temporal stability and performance.

    abstract::The dissociation between intact priming and reduced explicit memory in aging has been called into question on the basis of limited information that suggests that priming measures are less reliable than explicit memory measures. No aging study to date, however, has offered a comprehensive examination of the reliability...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.19.6.750

    authors: Fleischman DA,Gabrieli JD,Wilson RS,Moro TT,Bennett DA

    更新日期:2005-11-01 00:00:00

  • Chance guessing in a forced-choice recognition task and the detection of malingering.

    abstract::Guessing occurs on forced-choice (FC) tests for which responses cannot be based on relevant knowledge. Its importance is in inverse relation to the level of knowledge being measured, so that it becomes an increasing component of test scores as the level of knowledge decreases. It is also used as a benchmark to detect ...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.22.2.273

    authors: Flowers KA,Bolton C,Brindle N

    更新日期:2008-03-01 00:00:00

  • When memory does not fail: familiarity-based recognition in mild cognitive impairment and Alzheimer's disease.

    abstract::Recognition can be guided by familiarity, a restricted form of retrieval devoid of contextual recall, or by recollection, which occurs when retrieval is sufficient to support the full experience of remembering an episode. Recollection and familiarity were disentangled by testing recognition memory using silhouette obj...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.20.2.193

    authors: Westerberg CE,Paller KA,Weintraub S,Mesulam MM,Holdstock JS,Mayes AR,Reber PJ

    更新日期:2006-03-01 00:00:00

  • Faking bad: The neural correlates of feigning memory impairment.

    abstract:OBJECTIVE:The detection of malingering in cognitive performance is a challenge in clinical and legal environments. Neuroimaging may provide an objective method for delineation of malingering. METHOD:A heterogeneous with concern of gender and racial-ethnic identity of 22 healthy volunteers completed the Tombaugh Test o...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000251

    authors: Kosheleva E,Spadoni AD,Strigo IA,Buchsbaum MS,Simmons AN

    更新日期:2016-03-01 00:00:00

  • Intraindividual variability in neuropsychological performance predicts cognitive decline and death in HIV.

    abstract:OBJECTIVE:HIV-associated neurocognitive disorder (HAND) occurs in a significant percentage of HIV-infected (HIV+) adults. Increased intraindividual variability (IIV) in cognitive function may be an early marker of emerging neurocognitive disorder, which suggests that IIV may be a sensitive measure of neurologic comprom...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000482

    authors: Anderson AE,Jones JD,Thaler NS,Kuhn TP,Singer EJ,Hinkin CH

    更新日期:2018-11-01 00:00:00

  • Aging and implementation of encoding strategies in the generation of rhymes: the role of executive functions.

    abstract::This experiment examines whether the age-related decrease in the generation effect of rhymes is mediated by executive functioning. Young and elderly adults read and generated pairs of rhyming words for subsequent recall. Participants were also administered neuropsychological tests (executive and mnemonic functions). R...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.20.6.658

    authors: Taconnat L,Baudouin A,Fay S,Clarys D,Vanneste S,Tournelle L,Isingrini M

    更新日期:2006-11-01 00:00:00

  • Intraindividual cognitive variability before and after sports-related concussion.

    abstract:OBJECTIVE:Inconsistent performance is associated with cognitive dysfunction in a number of clinical populations. However, intraindividual cognitive variability in healthy individuals is poorly understood. Inconsistency poses a challenge to clinicians when interpreting change over time. This study examined intraindividu...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/a0033023

    authors: Rabinowitz AR,Arnett PA

    更新日期:2013-07-01 00:00:00

  • Time perception and reproduction in young adults with attention deficit hyperactivity disorder.

    abstract::Adults with attention deficit hyperactivity disorder (ADHD; n = 104) were compared with a control group (n = 64) on time estimation and reproduction tasks. Results were unaffected by ADHD subtype or gender. The ADHD group provided larger time estimations than the control group, particularly at long intervals. This bec...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037//0894-4105.15.3.351

    authors: Barkley RA,Murphy KR,Bush T

    更新日期:2001-07-01 00:00:00

  • Sustained attention in children with two etiologies of early hydrocephalus.

    abstract::Several studies have shown that children with spina bifida meningomyelocele (SBM) and hydrocephalus have attention problems on parent ratings and difficulties in stimulus orienting associated with a posterior brain attention system. Less is known about response control and inhibition associated with an anterior brain ...

    journal_title:Neuropsychology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1037/a0013373

    authors: Swartwout MD,Cirino PT,Hampson AW,Fletcher JM,Brandt ME,Dennis M

    更新日期:2008-11-01 00:00:00

  • Alpha event-related desynchronization preceding a go/no-go task: a high-resolution EEG study.

    abstract::The authors delineated the time evolution of alpha event-related desynchronization over human frontal, parietal, and primary sensorimotor areas during the expectancy of a go/no-go task. The main issue under investigation was whether anticipatory processes impinged upon cortical areas in sequential or parallel mode. Co...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.18.4.719

    authors: Babiloni C,Brancucci A,Arendt-Nielsen L,Babiloni F,Capotosto P,Carducci F,Cincotti F,Romano L,Chen AC,Rossini PM

    更新日期:2004-10-01 00:00:00

  • Phonological blocking during picture naming in dementia of the Alzheimer type.

    abstract::Individuals with dementia of the Alzheimer type (DAT; n = 53, ages 55-91), healthy older adults (n = 75, ages 59-91), and younger adults (n = 24, ages 18-24) performed a word-primed picture-naming task. Word primes were neutral (ready), semantically or phonologically related, or unrelated to the correct picture name. ...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/0894-4105.18.3.526

    authors: Faust ME,Balota DA,Multhaup KS

    更新日期:2004-07-01 00:00:00

  • Rhythmic auditory stimulation influences syntactic processing in children with developmental language disorders.

    abstract:OBJECTIVE:Children with developmental language disorders have been shown to be impaired not only in language processing (including syntax), but also in rhythm and meter perception. Our study tested the influence of external rhythmic auditory stimulation (i.e., musical rhythm) on syntax processing in children with speci...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/a0031277

    authors: Przybylski L,Bedoin N,Krifi-Papoz S,Herbillon V,Roch D,Léculier L,Kotz SA,Tillmann B

    更新日期:2013-01-01 00:00:00

  • Self-referencing and false memory in mild cognitive impairment due to Alzheimer's disease.

    abstract:OBJECTIVE:The present study explored the role of self-referencing on false alarm rates among people with mild cognitive impairment suggestive of the early signs of the Alzheimer's disease pathophysiologic process (MCI-AD). Given that people with MCI-AD demonstrate higher rates of false alarms and that false alarms have...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000186

    authors: Rosa NM,Deason RG,Budson AE,Gutchess AH

    更新日期:2015-09-01 00:00:00

  • Relationships among age, conditioned stimulus-unconditioned stimulus interval, and neuropsychological test performance.

    abstract::To evaluate the effect of age at various conditioned stimulus (CS)-unconditioned stimulus (US) intervals, 144 young, middle-aged, and older adults were tested on eyeblink classical conditioning at CS-US intervals of 500, 1,000, or 1,500 ms. Reaction time, response timing, motor learning, declarative memory, and attent...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037//0894-4105.13.1.90

    authors: Woodruff-Pak DS,Jaeger ME,Gorman C,Wesnes KA

    更新日期:1999-01-01 00:00:00

  • Beating their chests: University students with ADHD demonstrate greater attentional abilities on an inattentional blindness paradigm.

    abstract:OBJECTIVE:Adults diagnosed with attentional deficit disorder (ADHD) are easily distracted in many tasks. Yet ADHD performance on inattentional blindness (IB) tasks has not been examined. Such investigation may aid in discriminating between 3 ADHD models: the neurological model, the perceptual load theory, and the "hunt...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000189

    authors: Grossman ES,Hoffman YS,Berger I,Zivotofsky AZ

    更新日期:2015-11-01 00:00:00

  • Short-term memory for duration and distance in humans: role of the hippocampus.

    abstract::Control participants and hypoxic participants with bilateral hippocampal damage were tested for short-term memory (STM) for presentation duration of a single object, STM for a single object, STM for spatial distance information, and time estimation. Delays of 1, 4, 8, 12, or 16 s were used for all the STM and time est...

    journal_title:Neuropsychology

    pub_type: 临床试验,杂志文章

    doi:10.1037//0894-4105.15.1.58

    authors: Kesner RP,Hopkins RO

    更新日期:2001-01-01 00:00:00

  • Reading in developmental prosopagnosia: Evidence for a dissociation between word and face recognition.

    abstract:OBJECTIVE:Recent models suggest that face and word recognition may rely on overlapping cognitive processes and neural regions. In support of this notion, face recognition deficits have been demonstrated in developmental dyslexia. Here we test whether the opposite association can also be found, that is, impaired reading...

    journal_title:Neuropsychology

    pub_type: 杂志文章

    doi:10.1037/neu0000428

    authors: Starrfelt R,Klargaard SK,Petersen A,Gerlach C

    更新日期:2018-02-01 00:00:00